UY33776A - Ácidos 1-bencilcicloalquilcarboxílicos sustituidos y su uso - Google Patents

Ácidos 1-bencilcicloalquilcarboxílicos sustituidos y su uso

Info

Publication number
UY33776A
UY33776A UY33776A UY33776A UY33776A UY 33776 A UY33776 A UY 33776A UY 33776 A UY33776 A UY 33776A UY 33776 A UY33776 A UY 33776A UY 33776 A UY33776 A UY 33776A
Authority
UY
Uruguay
Prior art keywords
bencilcicloalquilcarboxílicos
acids substituted
prevention
treatment
diseases
Prior art date
Application number
UY33776A
Other languages
English (en)
Inventor
Lampe Dr Thomas
Dr Michael G Hahn
Stasch Prof Dr Johannes-Peter
Schlemmer Dr Karl-Heinz
Wunder Dr Frank
El Sheikh Dr Sherif
Li Dr Volkhart Min Jian
Becker Dr Eva-Maria
Stoll Dr Friederike
Knorr Dr Andreas
Kolkhof Dr Peter
Woltering Dr Elisabeth
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102010062544A external-priority patent/DE102010062544A1/de
Priority claimed from DE102011006974A external-priority patent/DE102011006974A1/de
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of UY33776A publication Critical patent/UY33776A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton

Abstract

La presente solicitud se refiere a nuevos derivados de ácido 1-bencilcicloalquilcarboxílico sustituidos, procedimientos para su preparación, su uso para el tratamiento y/o la prevención de enfermedades así como su uso para la preparación de medicamentos para el tratamiento y/o la prevención de enfermedades, especialmente para el tratamiento y/o la prevención enfermedades cardiovasculares.
UY33776A 2010-12-07 2011-12-07 Ácidos 1-bencilcicloalquilcarboxílicos sustituidos y su uso UY33776A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010062544A DE102010062544A1 (de) 2010-12-07 2010-12-07 Substituierte 1-Benzylcycloalkylcarbonsäuren und ihre Verwendung
DE102011006974A DE102011006974A1 (de) 2011-04-07 2011-04-07 Substituierte 1-Benzylcycloalkylcarbonsäuren und ihre Verwendung

Publications (1)

Publication Number Publication Date
UY33776A true UY33776A (es) 2012-06-29

Family

ID=45463539

Family Applications (1)

Application Number Title Priority Date Filing Date
UY33776A UY33776A (es) 2010-12-07 2011-12-07 Ácidos 1-bencilcicloalquilcarboxílicos sustituidos y su uso

Country Status (26)

Country Link
US (1) US9018258B2 (es)
EP (1) EP2649045B1 (es)
JP (1) JP5989660B2 (es)
KR (1) KR20130136504A (es)
CN (1) CN103492361B (es)
AP (1) AP2013006953A0 (es)
AR (1) AR084220A1 (es)
AU (1) AU2011340721A1 (es)
BR (1) BR112013013663A2 (es)
CA (1) CA2819880C (es)
CL (1) CL2013001600A1 (es)
CO (1) CO6771409A2 (es)
CR (1) CR20130259A (es)
DO (1) DOP2013000125A (es)
EA (1) EA201300669A1 (es)
EC (1) ECSP13012668A (es)
ES (1) ES2544532T3 (es)
HK (1) HK1192879A1 (es)
IL (1) IL226422A0 (es)
MA (1) MA34721B1 (es)
MX (1) MX2013006053A (es)
SG (1) SG190296A1 (es)
TW (1) TW201249782A (es)
UY (1) UY33776A (es)
WO (1) WO2012076466A2 (es)
ZA (1) ZA201305076B (es)

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CN112055584A (zh) 2018-04-30 2020-12-08 拜耳公司 sGC活化剂和sGC刺激剂用于治疗认知障碍的用途
SG11202011018PA (en) 2018-05-15 2020-12-30 Bayer Ag 1,3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization
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US10905667B2 (en) 2018-07-24 2021-02-02 Bayer Pharma Aktiengesellschaft Orally administrable modified-release pharmaceutical dosage form
CA3126778A1 (en) 2019-01-17 2020-07-23 Bayer Aktiengesellschaft Methods to determine whether a subject is suitable of being treated with an agonist of soluble guanylyl cyclase (sgc)
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WO2020245342A1 (en) 2019-06-07 2020-12-10 Bayer Aktiengesellschaft The use of sgc activators for the treatment of ophthalmologic diseases
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Also Published As

Publication number Publication date
EP2649045A2 (de) 2013-10-16
EA201300669A1 (ru) 2013-11-29
WO2012076466A2 (de) 2012-06-14
ECSP13012668A (es) 2013-08-30
CN103492361B (zh) 2015-07-15
US20120172448A1 (en) 2012-07-05
AR084220A1 (es) 2013-05-02
CO6771409A2 (es) 2013-10-15
JP5989660B2 (ja) 2016-09-07
US9018258B2 (en) 2015-04-28
EP2649045B1 (de) 2015-05-27
TW201249782A (en) 2012-12-16
CL2013001600A1 (es) 2013-10-25
CR20130259A (es) 2013-06-28
ES2544532T3 (es) 2015-09-01
AP2013006953A0 (en) 2013-06-30
IL226422A0 (en) 2013-07-31
MX2013006053A (es) 2013-06-18
SG190296A1 (en) 2013-06-28
CN103492361A (zh) 2014-01-01
AU2011340721A1 (en) 2013-06-20
MA34721B1 (fr) 2013-12-03
ZA201305076B (en) 2014-12-23
CA2819880C (en) 2019-01-22
HK1192879A1 (zh) 2014-09-05
DOP2013000125A (es) 2013-11-15
JP2014510017A (ja) 2014-04-24
WO2012076466A3 (de) 2012-08-30
KR20130136504A (ko) 2013-12-12
CA2819880A1 (en) 2012-06-14
BR112013013663A2 (pt) 2016-09-06

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