BR112012011478A2 - composições fosfolipídicas terapêuticas concentradas. - Google Patents

composições fosfolipídicas terapêuticas concentradas.

Info

Publication number
BR112012011478A2
BR112012011478A2 BR112012011478A BR112012011478A BR112012011478A2 BR 112012011478 A2 BR112012011478 A2 BR 112012011478A2 BR 112012011478 A BR112012011478 A BR 112012011478A BR 112012011478 A BR112012011478 A BR 112012011478A BR 112012011478 A2 BR112012011478 A2 BR 112012011478A2
Authority
BR
Brazil
Prior art keywords
concentrated therapeutic
therapeutic phospholipid
phospholipid compositions
diseases
compositions
Prior art date
Application number
BR112012011478A
Other languages
English (en)
Other versions
BR112012011478B1 (pt
Inventor
Sampalis Fotini
Harland Henri
Original Assignee
Acasti Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43921214&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012011478(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acasti Pharma Inc filed Critical Acasti Pharma Inc
Publication of BR112012011478A2 publication Critical patent/BR112012011478A2/pt
Publication of BR112012011478B1 publication Critical patent/BR112012011478B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composições fosfolipídicas terapêuticas concentradas. a invenção refere a composições fosfolípicas terapêuticas concentradas; métodos para tratar ou previnir doenças associadas com doença cardiovascular, síndrome metabólica, inflamação e doenças associadas com as mesmas, doenças de neurodesenvolvimento e doenças neurodegenerativas, compreendendo a administração de uma quantidade eficaz de uma composição fosfolipídica terapêutica concentrada.
BR112012011478-6A 2009-10-29 2010-10-29 Composições fosfolipídicas terapêuticas concentradas e uso das referidas composições BR112012011478B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25610609P 2009-10-29 2009-10-29
US61/256,106 2009-10-29
PCT/CA2010/001720 WO2011050474A1 (en) 2009-10-29 2010-10-29 Concentrated therapeutic phospholipid compositions

Publications (2)

Publication Number Publication Date
BR112012011478A2 true BR112012011478A2 (pt) 2018-04-03
BR112012011478B1 BR112012011478B1 (pt) 2021-12-21

Family

ID=43921214

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012011478-6A BR112012011478B1 (pt) 2009-10-29 2010-10-29 Composições fosfolipídicas terapêuticas concentradas e uso das referidas composições

Country Status (24)

Country Link
US (4) US8586567B2 (pt)
EP (2) EP2493478B8 (pt)
JP (3) JP5827625B2 (pt)
KR (1) KR101788342B1 (pt)
CN (2) CN102753182B (pt)
AR (1) AR078850A1 (pt)
AU (1) AU2010312238C1 (pt)
BR (1) BR112012011478B1 (pt)
CA (2) CA2989078C (pt)
CL (1) CL2012001124A1 (pt)
DK (1) DK2493478T3 (pt)
ES (1) ES2663714T3 (pt)
HK (1) HK1208800A1 (pt)
IL (2) IL219457B (pt)
MX (2) MX366175B (pt)
NO (1) NO2493478T3 (pt)
NZ (1) NZ600167A (pt)
PT (1) PT2493478T (pt)
RU (2) RU2642653C2 (pt)
SA (1) SA110310813B1 (pt)
TW (2) TWI573591B (pt)
UY (1) UY32989A (pt)
WO (1) WO2011050474A1 (pt)
ZA (1) ZA201203367B (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1417211T3 (da) * 2001-07-27 2007-10-08 Neptune Technologies & Bioress Naturlige phospholipider af marin oprindelse, der indeholder flavonoider og polyumættede phospholipider, og deres anvendelse
PT2144618E (pt) 2007-03-28 2013-07-08 Aker Biomarine Asa Composições bioeficazes de óleo de krill
US20130295171A1 (en) 2009-07-23 2013-11-07 U.S NUTRACEUTICALS, LLC d/b/a Valensa International Krill oil and reacted astaxanthin composition and associated method
RU2642653C2 (ru) 2009-10-29 2018-01-25 Акасти Фарма, Инк. Концентрированные терапевтические фосфолипидные композиции
US8974818B2 (en) * 2010-01-20 2015-03-10 Henry Wu Custom-formulated phospholipid microbubbles and methods and uses thereof
US8663704B2 (en) 2010-04-30 2014-03-04 U.S. Nutraceuticals, LLC Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans
US9763897B2 (en) 2010-04-30 2017-09-19 U.S. Nutraceuticals, LLC Therapeutic astaxanthin and phospholipid composition and associated method
US8952000B2 (en) * 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
CN102210764B (zh) * 2011-05-30 2013-04-17 陕西师范大学 甜杏仁油在制备治疗心肌缺血再灌注损伤药物中应用
WO2013033618A1 (en) 2011-09-02 2013-03-07 Arctic Nutrition As Lipid compositions with high dha content
RU2464986C1 (ru) * 2011-11-09 2012-10-27 Вячеслав Анатольевич Игнатьев Способ проф. игнатьева снижения массы тела человека
WO2013149384A1 (en) * 2012-04-05 2013-10-10 Nippon Suisan Kaisha, Ltd. Brain atrophy prevention agent
CA2916208A1 (en) * 2012-06-17 2013-12-27 Matinas Biopharma, Inc. Omega-3 pentaenoic acid compositions and methods of use
DE212013000066U1 (de) 2012-07-19 2014-09-25 U.S. Nutraceuticals Llc Dba Valensa International Krillöl und reagierte Astaxanthinzusammensetzung
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
WO2014143275A1 (en) * 2013-03-13 2014-09-18 Matinas Biopharma Inc. Omega-3 pentaenoic acid compositions and methods of use
AU2014229540A1 (en) * 2013-03-14 2015-10-08 Aker Biomarine Antarctic As Omega- 3 phospholipid supplements for improved brain maturity
AU2014203179C1 (en) * 2013-06-14 2017-05-04 Aker Biomarine Antarctic As Lipid extraction processes
US9233114B2 (en) 2013-12-05 2016-01-12 Buriva, LLC Dietary supplement containing phospholipid-DHA derived from eggs
US9216199B2 (en) 2013-12-05 2015-12-22 Buriva, LLC Nutritional supplement containing phospholipid-DHA derived from eggs
US9549937B2 (en) 2013-12-05 2017-01-24 Burvia, LLC. Composition containing phospholipid-DHA and folate
US9610302B2 (en) 2013-12-05 2017-04-04 Buriva, LLC. Composition containing phospholipid-DHA and B vitamins
GB201400431D0 (en) * 2014-01-10 2014-02-26 Aker Biomarine As Phospholipid compositions and their preparation
GB201402457D0 (en) * 2014-02-12 2014-03-26 Aker Biomarine As Capsules containing high doses of phospholipids
GB201402450D0 (en) 2014-02-12 2014-03-26 Aker Biomarine As Liquid phospholipid-containing compositions for preperation of pharmaceuticals
WO2015142999A1 (en) * 2014-03-19 2015-09-24 U.S. Nutraceuticals, Llc D/B/A Valensa International Composition and method to improve blood lipid profiles and reduce low density lipoprotein (ldl) per-oxidation in humans using algae based oils and astaxanthin
GB201407345D0 (en) 2014-04-25 2014-06-11 Aker Biomarine As Krill Phospholipid compositions
EP3232798A1 (en) 2014-12-19 2017-10-25 Aker Biomarine Antarctic AS Enhanced omega-3 formulations
KR102079747B1 (ko) * 2015-02-11 2020-02-20 에이커 바이오마린 앤탁틱 에이에스 지질 조성물
DE102015106095A1 (de) * 2015-04-21 2016-10-27 K. D. Pharma Bexbach Gmbh Neue Anwendung von Omega-3-Fettsäure(n)
US10328105B2 (en) * 2015-05-27 2019-06-25 Rimfrost Technologies As Flowable concentrated phospholipid krill oil composition
WO2017031502A1 (en) * 2015-08-20 2017-02-23 Avoca, Inc. Method for increasing muscle growth using krill extract
WO2017211780A1 (en) * 2016-06-06 2017-12-14 Ludwig-Maximilians-Universitaet Muenchen Kaempferol for the treatment of cardiac diseases
CN106336433B (zh) * 2016-08-22 2018-04-27 浙江大学 一种拟南芥活性组分提取物及其制备方法和应用
RS64705B1 (sr) * 2017-12-22 2023-11-30 Pharmalink International Ltd Kompozicije koje sadrže ekstrakt lipida dagnјi i ulje krila, i nјihove medicinske primene
CN109198628A (zh) * 2018-10-10 2019-01-15 陶燃 一种治疗抑郁症及焦虑症的组合物及其用途
JP2022521181A (ja) * 2019-02-12 2022-04-06 アカスティ ファーマ インコーポレイティド 高レベルの遊離脂肪酸を含むオキアミ抽出物から濃縮された治療用リン脂質組成物を製造する方法
CN113543776A (zh) 2019-03-05 2021-10-22 四川国为制药有限公司 脂肪酸组合物及其应用
EP3958973A4 (en) * 2019-04-26 2023-06-07 Cytosolve, Inc. COMPOSITIONS TO IMPROVE BRAIN HEALTH AND MEMORY
WO2021138742A1 (en) * 2020-01-10 2021-07-15 Acasti Pharma Inc. Composition that promote pro-resolving mediators
WO2022140580A1 (en) * 2020-12-24 2022-06-30 Orn Almarsson Xanthophyll derivatives
WO2023107415A1 (en) * 2021-12-06 2023-06-15 The Children's Medical Center Corporation Compositions comprising modified phospholipids and uses thereof

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT331374B (de) * 1972-12-22 1976-08-25 Studiengesellschaft Kohle Mbh Verfahren zur gewinnung von fetten und olen aus pflanzlichen und tierischen produkten
JPS5248191B2 (pt) 1974-12-27 1977-12-08
JPS53112195A (en) 1977-03-10 1978-09-30 Nippon Paint Co Ltd Method for producing food for fish
CA1098900A (en) 1977-12-14 1981-04-07 Sergei V. Rogozhin Method for the processing of krill to produce protein, lipids and chitin
JPS6029463B2 (ja) 1978-08-09 1985-07-10 味の素株式会社 オキアミエキスの品質改善法
NO147365C (no) 1980-11-27 1983-03-30 Jan Raa Fremgangsmaate til fremstilling av astaxanthin i en form som er egnet for innlemmelse i for for oppdrettfisk.
WO1984001715A1 (en) 1982-10-25 1984-05-10 Hellgren Lars G I Enzyme composition for therapeutical and/or non-therapeutical cleaning, the use thereof and preparation of the composition
JPS59196032A (ja) 1983-04-23 1984-11-07 Fumio Nishikawa オキアミの変性防止及び鮮度保持の方法
JPS603507A (ja) 1983-06-21 1985-01-09 Hitachi Ltd 配線パタ−ン検出装置
JPS60153779A (ja) 1984-01-24 1985-08-13 Hohnen Oil Co Ltd 栄養補助食品
JPS6035057A (ja) 1984-06-27 1985-02-22 San Ei Chem Ind Ltd 黄橙色ないし赤橙色色素の製法
US5006281A (en) * 1985-03-26 1991-04-09 Century Laboratories, Inc. Process for the production of a marine animal oil
IT1187687B (it) 1985-07-17 1987-12-23 Inverni Della Beffa Spa Composizioni farmaceutiche contenenti come principi attivi flavanolignani e fosfolipidi
IT1215291B (it) 1985-07-17 1990-01-31 Inverni Della Beffa Spa Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.
JPS6323819A (ja) 1986-07-16 1988-02-01 Kao Corp 血小板凝集抑制剤
IT1201149B (it) 1987-01-14 1989-01-27 Indena Spa Complessi di bioflavonoidi con fosfolipidi,loro preparazione,uso e composizioni farmaceutici e cosmetiche
IT1201151B (it) 1987-01-14 1989-01-27 Indena Spa Complessi fosfolipidici con estratti da vitis vinifera,procedimento per la loro preparazione e composizioni che li cntengono
JPS63295698A (ja) 1987-05-27 1988-12-02 Showa Denko Kk α−リノレン酸の分離精製法
US4915876A (en) * 1987-07-20 1990-04-10 General Mills, Inc. Process for the deodorization and stabilization of polyunsaturated oils
JPS6450890A (en) 1987-08-20 1989-02-27 Nippon Oils & Fats Co Ltd Production of docosahexaenoic acid-containing phosphatidyl choline
JPH02167055A (ja) 1988-12-19 1990-06-27 Seiji Nojima 機能性練製品
JP2909508B2 (ja) * 1989-02-14 1999-06-23 マルハ株式会社 オキアミリン脂質の分取方法
JP2963152B2 (ja) 1990-06-28 1999-10-12 クロリンエンジニアズ株式会社 オキアミからの色素の抽出分離方法
JP3092180B2 (ja) 1991-02-27 2000-09-25 日本油脂株式会社 低密度リポ蛋白受容体活性化剤
EP0507363B1 (en) 1991-04-02 1993-05-19 N.V. Vandemoortele International Process for the continuous removal of a gum phase from triglyceride oil
SE9101642D0 (sv) * 1991-05-30 1991-05-30 Kabi Pharmacia Ab Phospholipids
DE4219360C2 (de) 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
GB9301629D0 (en) 1993-01-27 1993-03-17 Scotia Holdings Plc Formulations containing unsaturated fatty acids
JP2558050B2 (ja) 1993-02-18 1996-11-27 イセ食品株式会社 鶏用飼料
GB2290965A (en) * 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
JPH08198754A (ja) 1995-01-23 1996-08-06 Yakult Honsha Co Ltd 脳機能改善剤
ES2088750B1 (es) 1995-01-24 1997-03-01 Cruz Bartolome A Grillo Procedimiento para la preparacion y conservacion de un suplemento alimenticio natural a base del crustaceo euphasia superba del antartico aplicable para el consumo humano.
JP3398248B2 (ja) 1995-03-16 2003-04-21 新日本石油株式会社 キサントフィル化合物の精製方法
JPH08302382A (ja) 1995-05-09 1996-11-19 Nippon Synthetic Chem Ind Co Ltd:The 魚油の精製法
GB9510636D0 (en) 1995-05-25 1995-07-19 Scotia Holdings Plc Fatty acid treatment
JPH09124470A (ja) * 1995-10-26 1997-05-13 Suntory Ltd 抗ストレス組成物
JP2815562B2 (ja) 1995-11-13 1998-10-27 植田製油株式会社 高度不飽和脂肪酸含有油脂の精製方法
WO1997039759A2 (en) 1996-04-24 1997-10-30 Brigham And Women's Hospital Omega-3 fatty acids and omega-3 phosphatidylcholine in the treatment of bipolar disorder
JPH10155459A (ja) 1996-11-27 1998-06-16 Suntory Ltd アスタキサンチン含有飲食物
US6055936A (en) * 1997-01-21 2000-05-02 Collin; Peter Donald Sea cucumber carotenoid lipid fractions and process
US6852870B2 (en) 1999-03-22 2005-02-08 Andrew Stoll Omega-3 fatty acids in the treatment of depression
US7906153B2 (en) 1998-04-08 2011-03-15 Theta Biomedical Consulting & Development Co., Inc. Anti-inflammatory compositions for treating multiple sclerosis
CA2334022C (en) 1998-06-05 2008-12-02 Merck Patent Gesellschaft Mit Beschraenkter Haftung Contaminant reduced marine oil
JP2000060432A (ja) * 1998-08-27 2000-02-29 Nippon Kagaku Shiryo Kk 高度不飽和脂肪酸を多量に含有する高品質リン脂質の製造法
CA2251265A1 (en) 1998-10-21 2000-04-21 Universite De Sherbrooke Process for lipid extraction of aquatic animal tissues producing a dehydrated residue
US20030113432A1 (en) 1998-11-02 2003-06-19 Nippon Suisan Kaisha, Ltd. Process for making dried powdery and granular krill
CA2260397A1 (en) 1999-01-29 2000-07-29 Atlantis Marine Inc. Method of converting rendered triglyceride oil from marine sources into bland, stable food oil
CA2290885A1 (fr) * 1999-12-02 2001-06-02 Universite De Sherbrooke Methode pour la transformation des tissus du loup marin
KR100344907B1 (ko) 1999-12-13 2002-07-20 네오메가(주) 정제 어유 제조방법
KR20020037140A (ko) 2000-11-13 2002-05-18 권승룡 지질 저하 활성을 갖는 플라보노이드를 포함하는 터몹시스알터니플로라 추출물 및 이를 유효 성분으로 하는 약학적조성물
CA2325377A1 (en) * 2000-11-14 2002-05-14 Adrien R. Beaudoin Process for the extraction of lipids from bird's skin and fat tissues
IL142952A (en) * 2001-05-03 2005-12-18 Enzmotec Ltd Process for enzyme-catalyzed production of 1,2 diacylated phospholipids
WO2002092540A1 (en) 2001-05-14 2002-11-21 Martek Biosciences Corporation Production and use of a polar lipid-rich fraction containing omega-3 and/or omega-6 highly unsatruated fatty acids from microbes, genetically modified plant seeds and marine organisms
EP1406641B1 (en) 2001-06-18 2009-01-07 Neptune Technologies & Bioressources Inc. Krill extracts for prevention and/or treatment of cardiovascular diseases
DK1417211T3 (da) 2001-07-27 2007-10-08 Neptune Technologies & Bioress Naturlige phospholipider af marin oprindelse, der indeholder flavonoider og polyumættede phospholipider, og deres anvendelse
ITMI20012384A1 (it) * 2001-11-12 2003-05-12 Quatex Nv Uso di acidi grassi poliinsaturi per la prevenzione primaria di eventi cardiovascolari maggiori
US7488503B1 (en) 2003-03-31 2009-02-10 Mccormick & Company, Inc. Encapsulation compositions and processes for preparing the same
EP1684776A1 (en) * 2003-07-25 2006-08-02 Washington State University Research Foundation Natural astaxanthin extract reduces dna oxidation
WO2005025586A1 (en) 2003-09-12 2005-03-24 Access Business Group International Llc Cytokine modulators and related method of use
IL158552A0 (en) 2003-10-22 2004-05-12 Enzymotec Ltd Lipids containing omega-3 fatty acids
US7935365B2 (en) 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US8052992B2 (en) 2003-10-22 2011-11-08 Enzymotec Ltd. Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions
US8673634B2 (en) 2003-11-13 2014-03-18 Massachusetts Eye & Ear Infirmary Method for the treatment of hearing loss
US7572464B2 (en) * 2004-01-30 2009-08-11 Bionovate Limited Solvent extraction of lipids such as essential fatty acids
AU2007241642B2 (en) 2006-04-20 2013-01-31 Callaghan Innovation Process for separating lipid materials
WO2008149177A2 (en) 2006-05-05 2008-12-11 Natural Asa Marine lipid compositions and uses thereof
US20080021000A1 (en) 2006-07-19 2008-01-24 Su Chen Mixtures of and methods of use for polyunsaturated fatty acid-containing phospholipids and alkyl ether phospholipids species
CA2669847A1 (en) 2006-11-16 2008-05-22 Pronova Biopharma Norge As Process for production of omega-3 rich marine phospholipids from krill
US8697138B2 (en) * 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
PT2144618E (pt) 2007-03-28 2013-07-08 Aker Biomarine Asa Composições bioeficazes de óleo de krill
US20090118227A1 (en) * 2007-11-07 2009-05-07 Bristol-Myers Squibb Company Carotenoid-containing compositions and methods
EP2085089A1 (en) 2008-02-01 2009-08-05 KTB-Tumorforschungs GmbH Phospholipids Containing omega-3-Fatty Acids for the Treatment of Overweight, Obesity and Addictive Behavior
WO2009132463A1 (en) 2008-05-02 2009-11-05 Neptune Technologies & Bioressources Inc. New deodorization method and organoleptic improvement of marine oil extracts
CN101333229A (zh) 2008-05-10 2008-12-31 中国海洋大学 一种提取富含二十碳五烯酸及二十二碳六烯酸磷脂的方法
EP2405902B1 (en) 2009-03-09 2021-07-21 Basf As Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
WO2010109330A2 (en) * 2009-03-27 2010-09-30 University Of Oxford Cholesterol level lowering liposomes
RU2642653C2 (ru) * 2009-10-29 2018-01-25 Акасти Фарма, Инк. Концентрированные терапевтические фосфолипидные композиции
WO2011137160A2 (en) * 2010-04-30 2011-11-03 U.S. Nutraceuticals, Llc D/B/A Valensa International Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (ldl) per-oxidation in humans

Also Published As

Publication number Publication date
US20110160161A1 (en) 2011-06-30
SA110310813B1 (ar) 2014-06-17
CA2989078A1 (en) 2011-05-05
JP2018138612A (ja) 2018-09-06
WO2011050474A1 (en) 2011-05-05
CL2012001124A1 (es) 2013-03-15
US20140141074A1 (en) 2014-05-22
DK2493478T3 (en) 2018-03-26
CN102753182A (zh) 2012-10-24
CN104434935A (zh) 2015-03-25
CA2989078C (en) 2020-06-30
IL262567B (en) 2021-08-31
TW201603813A (zh) 2016-02-01
US20160375043A1 (en) 2016-12-29
CA2779162C (en) 2018-02-06
UY32989A (es) 2011-04-29
AU2010312238A1 (en) 2012-06-14
BR112012011478B1 (pt) 2021-12-21
IL262567A (en) 2018-12-31
NO2493478T3 (pt) 2018-07-21
KR20130006589A (ko) 2013-01-17
CA2779162A1 (en) 2011-05-05
JP5827625B2 (ja) 2015-12-02
JP2015147793A (ja) 2015-08-20
US10617702B2 (en) 2020-04-14
RU2017139767A3 (pt) 2020-02-28
NZ600167A (en) 2014-06-27
ES2663714T3 (es) 2018-04-16
US8586567B2 (en) 2013-11-19
TW201119658A (en) 2011-06-16
CN104434935B (zh) 2019-07-16
EP3335713A1 (en) 2018-06-20
MX2012004977A (es) 2012-11-06
CN102753182B (zh) 2014-10-29
US9475830B2 (en) 2016-10-25
PT2493478T (pt) 2018-04-03
RU2017139767A (ru) 2019-02-12
JP6346121B2 (ja) 2018-06-20
EP2493478B8 (en) 2018-03-28
TWI494110B (zh) 2015-08-01
JP2013508431A (ja) 2013-03-07
KR101788342B1 (ko) 2017-10-19
EP2493478A1 (en) 2012-09-05
HK1208800A1 (en) 2016-03-18
IL219457A0 (en) 2012-06-28
AU2010312238C1 (en) 2017-03-23
EP3335713B1 (en) 2022-08-31
EP2493478A4 (en) 2013-02-27
US20190060332A1 (en) 2019-02-28
AU2010312238B2 (en) 2016-08-11
RU2642653C2 (ru) 2018-01-25
EP2493478B1 (en) 2018-02-21
MX366175B (es) 2019-07-01
RU2755902C2 (ru) 2021-09-22
ZA201203367B (en) 2013-08-28
US10130644B2 (en) 2018-11-20
AR078850A1 (es) 2011-12-07
RU2012122059A (ru) 2013-12-10
TWI573591B (zh) 2017-03-11
IL219457B (en) 2019-05-30

Similar Documents

Publication Publication Date Title
BR112012011478A2 (pt) composições fosfolipídicas terapêuticas concentradas.
BR112012016879A2 (pt) Derivados de fumarato de acido graxo e seus usos
EA201200551A1 (ru) Фармацевтическая композиция, фармацевтическая дозированная форма, способы их получения и применения для лечения
UA96441C2 (ru) Фармацевтическая композиция, которая содержит аналог тиазолидиндиона митоглитазон, для лечения заболеваний, опосредованных метаболическим воспалением
EA201001639A1 (ru) Композиции и способы их получения и применения
EA201491060A1 (ru) Новые производные трифторметилоксадиазола и их применение для лечения заболевания
EA201490228A1 (ru) Новые производные трифторметилоксадиазола и их применение для лечения заболевания
EA201290919A1 (ru) Индазольные соединения и их применение
NZ618734A (en) Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas
EA201490748A1 (ru) Лечение рассеянного склероза комбинацией лахинимода и финголимода
BR112012016853A2 (pt) "composições farmacêuticas para administração oral de peptídeos de insulina".
EA201491358A1 (ru) Вводимые перорально кортикостероидные композиции
UY31228A1 (es) Ariloxazoles sustituidos y su uso
BR112014031394A2 (pt) composições e métodos para absorção transmucosa
CR20110255A (es) Nuevos compuestos 578
MX2013003635A (es) Compuestos de n-heteroarilo.
MX360554B (es) Composiciones que comprenden y metodos que utilizan inhibidores de co-transportadores de glucosa-sodio 1 y 2.
BR112014005025A2 (pt) composição farmacêutica para uso no tratamento de uma doença neurodegenerativa
BR112013018286A2 (pt) derivados d azetidina úteis para o tratamento de doenças metabólicas e inflamatórias
MX2016000294A (es) Composicion farmaceutica para liberacion sostenida de lanreotida.
EA201201296A1 (ru) Способы лечения диабетических язв стопы
MX2022001796A (es) Metodos y composiciones para inhibir los sintomas asociados con la veisalgia.
TN2014000046A1 (en) Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one
BR112014030534A2 (pt) composições de galacto-ramnogalacturonato para o tratamento de doenças associadas com óxido nítrico sintase induzível elevada
BR112013026680A2 (pt) composto, método de tratamento de uma doença inflamatória e composição farmacêutica

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25G Requested change of headquarter approved

Owner name: ACASTI PHARMA, INC. (CA)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/10/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.