BR112012008033A2 - sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo subcutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação do nervo trigêmeo - Google Patents

sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo subcutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação do nervo trigêmeo

Info

Publication number
BR112012008033A2
BR112012008033A2 BR112012008033A BR112012008033A BR112012008033A2 BR 112012008033 A2 BR112012008033 A2 BR 112012008033A2 BR 112012008033 A BR112012008033 A BR 112012008033A BR 112012008033 A BR112012008033 A BR 112012008033A BR 112012008033 A2 BR112012008033 A2 BR 112012008033A2
Authority
BR
Brazil
Prior art keywords
trigeminal nerve
condition
treating
neurological disorder
nerve stimulation
Prior art date
Application number
BR112012008033A
Other languages
English (en)
Inventor
Christopher M Degiorgio
Ian A Cook
Leon Ekchian
Original Assignee
Neurosigma Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosigma Inc, Univ California filed Critical Neurosigma Inc
Publication of BR112012008033A2 publication Critical patent/BR112012008033A2/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0504Subcutaneous electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36057Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36064Epilepsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067Movement disorders, e.g. tremor or Parkinson disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071Pain
    • A61N1/36075Headache or migraine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36096Mood disorders, e.g. depression, anxiety or panic disorder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • A61N1/3615Intensity
    • A61N1/3616Voltage density or current density
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • A61N1/36167Timing, e.g. stimulation onset
    • A61N1/36171Frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • A61N1/36167Timing, e.g. stimulation onset
    • A61N1/36175Pulse width or duty cycle

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Social Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Electroluminescent Light Sources (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio ou condição neutológicos, de um dist´rubio ou condição neurológicos, unidade de eletrodo subcutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação fo nervo trigêmeo a presente invenção divulgação dis respeito a métodos, dispositivos e sistemas usados para o tratamento de distúrbios neurológicos por intermédio da estimulação dos elementos superficiais do nervo trigêmeo (''tns''). mais especificamente, métodos minimamente invasivos de estimulação das ramificações superficiais do nervo trigêmeo localizadas extracraniamente na face, a saber os nervos supraorbital, supratraclear, infratraclear, auriculotemporal, zigomaticotemporal, zigomaticcorbital, zigomaticofacial, nasal, infraorbital, e mentoniana (também aludido coletivamente como o nervo trigêmeo superficial) são aqui divulgados. sistemas e dispositivos configurados para a estimulação terapêutica das ramificações dos nervos trigêmeos, tais como o nervo trigêmeo superficial, e seus métodos de aplicação também são descritos.
BR112012008033A 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo subcutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação do nervo trigêmeo BR112012008033A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24882709P 2009-10-05 2009-10-05
US28982909P 2009-12-23 2009-12-23
US30551410P 2010-02-17 2010-02-17
US35464110P 2010-06-14 2010-06-14
PCT/US2010/051544 WO2011044178A1 (en) 2009-10-05 2010-10-05 Extracranial implantable devices, systems and methods for the treatment of neurological disorders

Publications (1)

Publication Number Publication Date
BR112012008033A2 true BR112012008033A2 (pt) 2016-04-19

Family

ID=43857099

Family Applications (4)

Application Number Title Priority Date Filing Date
BR112012008033A BR112012008033A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo subcutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação do nervo trigêmeo
BR112012008038A BR112012008038A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico, unidade de eletrodo subcutâneo, método para tratar um distúrbio neuropsiquiátrico, e, kit para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico
BR112012008028A BR112012008028A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsquiátrico, unidade de eletrodo cutâneo, método para tratar um distúrbio neuropsquiátrico, e, kit para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico
BR112012008029A BR112012008029A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação de nervo trigêmeo para o tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo cutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação de nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos

Family Applications After (3)

Application Number Title Priority Date Filing Date
BR112012008038A BR112012008038A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico, unidade de eletrodo subcutâneo, método para tratar um distúrbio neuropsiquiátrico, e, kit para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico
BR112012008028A BR112012008028A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsquiátrico, unidade de eletrodo cutâneo, método para tratar um distúrbio neuropsquiátrico, e, kit para estimulação do nervo trigêmeo para tratamento de um distúrbio neuropsiquiátrico
BR112012008029A BR112012008029A2 (pt) 2009-10-05 2010-10-05 sistema para estimulação de nervo trigêmeo para o tratamento de um distúrbio ou condição neurológicos, unidade de eletrodo cutâneo, método para tratar um distúrbio ou condição neurológicos, e, kit para estimulação de nervo trigêmeo para tratamento de um distúrbio ou condição neurológicos

Country Status (9)

Country Link
US (17) US8688220B2 (pt)
EP (4) EP2485800B1 (pt)
JP (8) JP2013506533A (pt)
KR (6) KR20170127056A (pt)
AU (4) AU2010303586B2 (pt)
BR (4) BR112012008033A2 (pt)
CA (4) CA2776696C (pt)
MX (4) MX2012004053A (pt)
WO (4) WO2011044173A1 (pt)

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