BR112012006088A2 - métodos para caracterizar um paciente como respondedor ou não respondedor a uma terapia, para tratar um paciente, para determinar se um paciente é um respondedor ou um não respondedor a uma imunoterapêutica, uso de uma lista de gene, microarranjo, kit de diagnostic, composição, uso de uma composição, e, superfície sólida - Google Patents

métodos para caracterizar um paciente como respondedor ou não respondedor a uma terapia, para tratar um paciente, para determinar se um paciente é um respondedor ou um não respondedor a uma imunoterapêutica, uso de uma lista de gene, microarranjo, kit de diagnostic, composição, uso de uma composição, e, superfície sólida Download PDF

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Publication number
BR112012006088A2
BR112012006088A2 BR112012006088-0A BR112012006088A BR112012006088A2 BR 112012006088 A2 BR112012006088 A2 BR 112012006088A2 BR 112012006088 A BR112012006088 A BR 112012006088A BR 112012006088 A2 BR112012006088 A2 BR 112012006088A2
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Prior art keywords
genes
gene
patient
responder
identified
Prior art date
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BR112012006088-0A
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English (en)
Portuguese (pt)
Inventor
Vincent Brichard
Benjamin Georges Elie Lea Ghislain Dizier
Oliver Gruselle
Jamila Louahed
Fernando Ulloa-Montoya
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Glaxosmithkline Biologicals S.A.
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Publication of BR112012006088A2 publication Critical patent/BR112012006088A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BR112012006088-0A 2009-09-18 2010-09-17 métodos para caracterizar um paciente como respondedor ou não respondedor a uma terapia, para tratar um paciente, para determinar se um paciente é um respondedor ou um não respondedor a uma imunoterapêutica, uso de uma lista de gene, microarranjo, kit de diagnostic, composição, uso de uma composição, e, superfície sólida BR112012006088A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US27704609P 2009-09-18 2009-09-18
US61/277046 2009-09-18
US27838709P 2009-10-06 2009-10-06
GBGB0917457.4A GB0917457D0 (en) 2009-10-06 2009-10-06 Method
GB0917457.4 2009-10-06
US61/278387 2009-10-06
PCT/EP2010/063751 WO2011033095A1 (en) 2009-09-18 2010-09-17 Method for identifying whether a patient will be responder or not to immunotherapy

Publications (1)

Publication Number Publication Date
BR112012006088A2 true BR112012006088A2 (pt) 2020-08-11

Family

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Family Applications (1)

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BR112012006088-0A BR112012006088A2 (pt) 2009-09-18 2010-09-17 métodos para caracterizar um paciente como respondedor ou não respondedor a uma terapia, para tratar um paciente, para determinar se um paciente é um respondedor ou um não respondedor a uma imunoterapêutica, uso de uma lista de gene, microarranjo, kit de diagnostic, composição, uso de uma composição, e, superfície sólida

Country Status (14)

Country Link
US (1) US20110070268A1 (enExample)
EP (1) EP2478116A1 (enExample)
JP (1) JP2013505008A (enExample)
KR (1) KR20130055553A (enExample)
CN (1) CN102597269A (enExample)
AU (1) AU2010297248A1 (enExample)
BR (1) BR112012006088A2 (enExample)
CA (1) CA2773666A1 (enExample)
EA (1) EA201290107A1 (enExample)
GB (1) GB0917457D0 (enExample)
IL (1) IL218313A0 (enExample)
MX (1) MX2012003329A (enExample)
SG (1) SG179129A1 (enExample)
WO (1) WO2011033095A1 (enExample)

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Also Published As

Publication number Publication date
EA201290107A1 (ru) 2012-10-30
JP2013505008A (ja) 2013-02-14
AU2010297248A1 (en) 2012-04-12
CN102597269A (zh) 2012-07-18
KR20130055553A (ko) 2013-05-28
MX2012003329A (es) 2012-04-20
US20110070268A1 (en) 2011-03-24
IL218313A0 (en) 2012-04-30
CA2773666A1 (en) 2011-03-24
GB0917457D0 (en) 2009-11-18
WO2011033095A1 (en) 2011-03-24
EP2478116A1 (en) 2012-07-25
SG179129A1 (en) 2012-05-30

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