EA201290107A1 - Способ определения пациента как восприимчивого или не восприимчивого к иммунотерапии - Google Patents
Способ определения пациента как восприимчивого или не восприимчивого к иммунотерапииInfo
- Publication number
- EA201290107A1 EA201290107A1 EA201290107A EA201290107A EA201290107A1 EA 201290107 A1 EA201290107 A1 EA 201290107A1 EA 201290107 A EA201290107 A EA 201290107A EA 201290107 A EA201290107 A EA 201290107A EA 201290107 A1 EA201290107 A1 EA 201290107A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- sustainable
- methods
- gene expression
- expression profiles
- determining
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000009169 immunotherapy Methods 0.000 title 1
- 230000014509 gene expression Effects 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 101150010487 are gene Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 238000002493 microarray Methods 0.000 abstract 1
- 238000012737 microarray-based gene expression Methods 0.000 abstract 1
- 238000012243 multiplex automated genomic engineering Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27704609P | 2009-09-18 | 2009-09-18 | |
| US27838709P | 2009-10-06 | 2009-10-06 | |
| GBGB0917457.4A GB0917457D0 (en) | 2009-10-06 | 2009-10-06 | Method |
| PCT/EP2010/063751 WO2011033095A1 (en) | 2009-09-18 | 2010-09-17 | Method for identifying whether a patient will be responder or not to immunotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201290107A1 true EA201290107A1 (ru) | 2012-10-30 |
Family
ID=41393894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201290107A EA201290107A1 (ru) | 2009-09-18 | 2010-09-17 | Способ определения пациента как восприимчивого или не восприимчивого к иммунотерапии |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20110070268A1 (enExample) |
| EP (1) | EP2478116A1 (enExample) |
| JP (1) | JP2013505008A (enExample) |
| KR (1) | KR20130055553A (enExample) |
| CN (1) | CN102597269A (enExample) |
| AU (1) | AU2010297248A1 (enExample) |
| BR (1) | BR112012006088A2 (enExample) |
| CA (1) | CA2773666A1 (enExample) |
| EA (1) | EA201290107A1 (enExample) |
| GB (1) | GB0917457D0 (enExample) |
| IL (1) | IL218313A0 (enExample) |
| MX (1) | MX2012003329A (enExample) |
| SG (1) | SG179129A1 (enExample) |
| WO (1) | WO2011033095A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2906523A1 (en) * | 2013-03-15 | 2014-09-25 | Myriad Genetics, Inc. | Genes and gene signatures for diagnosis and treatment of melanoma |
| ES2946681T3 (es) | 2014-07-02 | 2023-07-24 | Myriad Mypath Llc | Genes y firmas génicas para el diagnóstico y tratamiento del melanoma |
| WO2016109546A2 (en) * | 2014-12-30 | 2016-07-07 | Genentech, Inc. | Methods and compositions for prognosis and treatment of cancers |
| KR20180126085A (ko) * | 2016-05-05 | 2018-11-26 | 난토믹스, 엘엘씨 | 체크포인트 부전 및 그 방법(checkpoint failure and methods therefor) |
| KR102169901B1 (ko) * | 2019-05-17 | 2020-10-26 | 연세대학교 산학협력단 | Dna 메틸화를 이용한 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트 |
| IL296568A (en) * | 2020-03-17 | 2022-11-01 | Regeneron Pharma | Methods and systems for determining responders to treatment |
| EP4161658A4 (en) * | 2020-06-01 | 2024-10-02 | Dana-Farber Cancer Institute, Inc. | Methods for modulating mhc-i expression and immunotherapy uses thereof |
| CN115495026B (zh) * | 2022-11-21 | 2023-03-10 | 杭州字节方舟科技有限公司 | 一种优化内存处理方法、装置、设备及存储介质 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| EP0671948B1 (en) | 1992-06-25 | 1997-08-13 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine composition containing adjuvants |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| JP3468773B2 (ja) | 1994-07-15 | 2003-11-17 | ザ ユニバーシティ オブ アイオワ リサーチ ファウンデーション | 免疫調節オリゴヌクレオチド |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US6303347B1 (en) | 1997-05-08 | 2001-10-16 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| CA2319309C (en) | 1998-02-05 | 2010-08-10 | Smithkline Beecham Biologicals S.A. | Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccination |
| DE69929444T2 (de) | 1998-08-10 | 2006-09-28 | Antigenics Inc., Woburn | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| CA2361009C (en) | 1999-01-29 | 2012-10-23 | Corixa Corporation | Her-2/neu fusion proteins |
| CN100430478C (zh) | 1999-03-11 | 2008-11-05 | 史密丝克莱恩比彻姆生物有限公司 | Casb618多核苷酸和多肽及其用途 |
| DK1187629T3 (da) | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| PL209127B1 (pl) | 2000-02-23 | 2011-07-29 | Smithkline Beecham Biolog | Środek farmaceutyczny do stosowania w immunoterapeutycznym leczeniu raka i sposób diagnozowania u pacjenta obecności lub podatności na raka |
| US20020076469A1 (en) * | 2000-10-31 | 2002-06-20 | Colgate-Palmolive Company | Composition and method |
| DE10127572A1 (de) * | 2001-05-30 | 2002-12-05 | Pathoarray Gmbh | Werkzeuge zur Diagnostik, molekularen Definition und Therapieentwicklung chronischer entzündlicher Gelenkerkrankungen |
| US7229774B2 (en) * | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| WO2003050257A2 (en) * | 2001-12-06 | 2003-06-19 | University Of Florida | Targeting leukemia cells |
| EP1482795B1 (en) | 2002-02-04 | 2009-11-11 | Corixa Corporation | New immunoeffector compounds |
| US20040248151A1 (en) * | 2002-04-05 | 2004-12-09 | Ventana Medical Systems, Inc. | Method for predicting the response to HER2-directed therapy |
| MXPA04012443A (es) | 2002-06-11 | 2005-04-19 | Glaxosmithkline Biolog Sa | Composiciones inmunogenicas. |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| WO2004076565A2 (en) * | 2003-02-25 | 2004-09-10 | Technical Knockout, Inc. | Improved coated weight plates, dumbbells and method of manufacture |
| EP1605811A4 (en) * | 2003-02-28 | 2008-06-11 | Bayer Pharmaceuticals Corp | EXPRESSION PROFILES FOR BREAST CANCER AND METHODS OF USE |
| US20050095607A1 (en) * | 2003-03-07 | 2005-05-05 | Arcturus Bioscience, Inc. University Of Louisville | Breast cancer signatures |
| EP1608964A4 (en) | 2003-03-14 | 2009-07-15 | Peter Maccallum Cancer Inst | CREATING AN EXPRESSION PROFILE OF TUMORS |
| US20040241725A1 (en) * | 2003-03-25 | 2004-12-02 | Wenming Xiao | Lung cancer detection |
| US7598287B2 (en) * | 2003-04-01 | 2009-10-06 | Medical College Of Georgia Research Institute, Inc. | Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities |
| JP2007507222A (ja) * | 2003-05-28 | 2007-03-29 | ゲノミック ヘルス， インコーポレイテッド | 化学療法に対する応答を予測するための遺伝子発現マーカー |
| EP2348110B1 (en) | 2003-05-30 | 2013-03-27 | OncoTherapy Science, Inc. | Process for screening a drug response in cancer patients |
| EP1651775A2 (en) * | 2003-06-18 | 2006-05-03 | Arcturus Bioscience, Inc. | Breast cancer survival and recurrence |
| EP1980629A3 (en) * | 2003-08-28 | 2008-12-17 | Ipsogen | Identification of an erbb2 gene expression signature in breast cancers |
| WO2005032495A2 (en) * | 2003-10-03 | 2005-04-14 | Bayer Pharmaceuticals Corporation | Gene expression profiles and methods of use |
| US20070110710A1 (en) * | 2003-11-05 | 2007-05-17 | New England Medical Center Hospitals, Inc. | Treatment with immunoregulatory t cells |
| WO2005075680A1 (ja) * | 2004-02-09 | 2005-08-18 | Fuso Pharmaceutical Industries, Ltd. | 核酸検出方法およびその利用 |
| US20060195266A1 (en) | 2005-02-25 | 2006-08-31 | Yeatman Timothy J | Methods for predicting cancer outcome and gene signatures for use therein |
| US20070237717A1 (en) * | 2004-04-05 | 2007-10-11 | Roland Martin | Methods for Selection of Subjects for Multiple Sclerosis Therapy |
| US7332281B2 (en) * | 2004-04-27 | 2008-02-19 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
| WO2006054129A1 (en) | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
| BRPI0518734A2 (pt) | 2004-11-30 | 2008-12-02 | Veridex Llc | prognàstico de cÂncer de pulmço |
| US20070059720A9 (en) * | 2004-12-06 | 2007-03-15 | Suzanne Fuqua | RNA expression profile predicting response to tamoxifen in breast cancer patients |
| US7666595B2 (en) | 2005-02-25 | 2010-02-23 | The Brigham And Women's Hospital, Inc. | Biomarkers for predicting prostate cancer progression |
| GB0504302D0 (en) | 2005-03-02 | 2005-04-06 | Univ Dublin | Markers for melanoma |
| EP1863930A2 (en) | 2005-04-01 | 2007-12-12 | NCC Technology Ventures Pte Limited | Materials and methods relating to breast cancer classification |
| WO2006124836A1 (en) | 2005-05-13 | 2006-11-23 | Duke University | Gene expression signatures for oncogenic pathway deregulation |
| US20070111257A1 (en) * | 2005-07-07 | 2007-05-17 | Kohne David E | Improved protein expression comparison assay results and applications |
| JP5171812B2 (ja) * | 2006-04-27 | 2013-03-27 | ユニベルシテ ドゥ モントリオール | 移植片対宿主病のリスクの評価および低減 |
| KR20090017655A (ko) * | 2006-06-02 | 2009-02-18 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 환자가 면역치료제에 대한 반응자일지의 여부를 확인하는 방법 |
| WO2009034055A1 (en) * | 2007-09-10 | 2009-03-19 | Novartis Forschungsstiftung, Zweigniederlassung | Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy |
| WO2009068621A1 (en) * | 2007-11-30 | 2009-06-04 | Glaxosmithkline Biologicals S.A. | Method for classifying cancer patients as responder or non-responder to immunotherapy |
-
2009
- 2009-10-06 GB GBGB0917457.4A patent/GB0917457D0/en not_active Ceased
-
2010
- 2010-09-17 MX MX2012003329A patent/MX2012003329A/es not_active Application Discontinuation
- 2010-09-17 SG SG2012017869A patent/SG179129A1/en unknown
- 2010-09-17 CA CA2773666A patent/CA2773666A1/en not_active Abandoned
- 2010-09-17 EP EP10757757A patent/EP2478116A1/en not_active Ceased
- 2010-09-17 EA EA201290107A patent/EA201290107A1/ru unknown
- 2010-09-17 JP JP2012529295A patent/JP2013505008A/ja not_active Ceased
- 2010-09-17 KR KR1020127009956A patent/KR20130055553A/ko not_active Withdrawn
- 2010-09-17 WO PCT/EP2010/063751 patent/WO2011033095A1/en not_active Ceased
- 2010-09-17 AU AU2010297248A patent/AU2010297248A1/en not_active Abandoned
- 2010-09-17 BR BR112012006088-0A patent/BR112012006088A2/pt not_active IP Right Cessation
- 2010-09-17 US US12/884,407 patent/US20110070268A1/en not_active Abandoned
- 2010-09-17 CN CN2010800494497A patent/CN102597269A/zh active Pending
-
2012
- 2012-02-26 IL IL218313A patent/IL218313A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013505008A (ja) | 2013-02-14 |
| AU2010297248A1 (en) | 2012-04-12 |
| CN102597269A (zh) | 2012-07-18 |
| KR20130055553A (ko) | 2013-05-28 |
| MX2012003329A (es) | 2012-04-20 |
| US20110070268A1 (en) | 2011-03-24 |
| BR112012006088A2 (pt) | 2020-08-11 |
| IL218313A0 (en) | 2012-04-30 |
| CA2773666A1 (en) | 2011-03-24 |
| GB0917457D0 (en) | 2009-11-18 |
| WO2011033095A1 (en) | 2011-03-24 |
| EP2478116A1 (en) | 2012-07-25 |
| SG179129A1 (en) | 2012-05-30 |
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