BR112012001653A2 - partícula de vetor lentiviral, genoma de vetor lentiviral pseudotipado em um envelope, sistema de acondicionamento de vetor lentiviral para produzir uma partícula de vetor lentiviral pesudotipado, célula, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, métodos para fazer uma partícula de vetor lentiviral, e para distribuir partículas de vetor lentiviral para células invitro, e vacina terapêutica ou profilática - Google Patents
partícula de vetor lentiviral, genoma de vetor lentiviral pseudotipado em um envelope, sistema de acondicionamento de vetor lentiviral para produzir uma partícula de vetor lentiviral pesudotipado, célula, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, métodos para fazer uma partícula de vetor lentiviral, e para distribuir partículas de vetor lentiviral para células invitro, e vacina terapêutica ou profiláticaInfo
- Publication number
- BR112012001653A2 BR112012001653A2 BR112012001653A BR112012001653A BR112012001653A2 BR 112012001653 A2 BR112012001653 A2 BR 112012001653A2 BR 112012001653 A BR112012001653 A BR 112012001653A BR 112012001653 A BR112012001653 A BR 112012001653A BR 112012001653 A2 BR112012001653 A2 BR 112012001653A2
- Authority
- BR
- Brazil
- Prior art keywords
- lentiviral vector
- particle
- vector
- cell
- lentiviral
- Prior art date
Links
- 239000013598 vector Substances 0.000 title 6
- 239000002245 particle Substances 0.000 title 4
- 239000013604 expression vector Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000004806 packaging method and process Methods 0.000 title 1
- 229940021993 prophylactic vaccine Drugs 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 229940021747 therapeutic vaccine Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/50—Colon
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36145—Special targeting system for viral vectors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22849109P | 2009-07-24 | 2009-07-24 | |
| PCT/US2010/042870 WO2011011584A1 (en) | 2009-07-24 | 2010-07-22 | Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012001653A2 true BR112012001653A2 (pt) | 2016-11-08 |
Family
ID=42727669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012001653A BR112012001653A2 (pt) | 2009-07-24 | 2010-07-22 | partícula de vetor lentiviral, genoma de vetor lentiviral pseudotipado em um envelope, sistema de acondicionamento de vetor lentiviral para produzir uma partícula de vetor lentiviral pesudotipado, célula, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, métodos para fazer uma partícula de vetor lentiviral, e para distribuir partículas de vetor lentiviral para células invitro, e vacina terapêutica ou profilática |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20110064763A1 (https=) |
| EP (2) | EP2770061B1 (https=) |
| JP (4) | JP2013500015A (https=) |
| KR (1) | KR101790187B1 (https=) |
| CN (1) | CN102482329B (https=) |
| AU (1) | AU2010276194B2 (https=) |
| BR (1) | BR112012001653A2 (https=) |
| CA (1) | CA2768938C (https=) |
| CY (1) | CY1121159T1 (https=) |
| DK (2) | DK2770061T3 (https=) |
| EA (1) | EA032403B1 (https=) |
| ES (2) | ES2702274T3 (https=) |
| HR (2) | HRP20140327T4 (https=) |
| HU (1) | HUE043032T2 (https=) |
| IL (1) | IL217679A (https=) |
| LT (1) | LT2770061T (https=) |
| ME (1) | ME01720B (https=) |
| MX (1) | MX2012001075A (https=) |
| NZ (1) | NZ597804A (https=) |
| PL (2) | PL2770061T3 (https=) |
| PT (2) | PT2770061T (https=) |
| RS (2) | RS53257B2 (https=) |
| SG (1) | SG177744A1 (https=) |
| SI (2) | SI2456786T2 (https=) |
| SM (2) | SMT201800656T1 (https=) |
| TR (1) | TR201819229T4 (https=) |
| WO (1) | WO2011011584A1 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2657737T3 (es) * | 2009-07-15 | 2018-03-06 | Calimmune Inc. | Vector dual para la inhibición del virus de la inmunodeficiencia humana |
| WO2012112691A1 (en) * | 2011-02-15 | 2012-08-23 | Immune Design Corp. | Methods for enhancing immunogen specific immune responses by vectored vaccines |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| WO2013116656A1 (en) * | 2012-02-03 | 2013-08-08 | Emory University | Immunostimulatory compositions, particles, and uses related thereto |
| EP2844746A4 (en) | 2012-03-26 | 2016-07-20 | Univ California | PSEUDOTYPIZED LENTIVIRES WITH NIPAH VIRUS COVERS AND METHOD OF USE THEREOF |
| US9713635B2 (en) * | 2012-03-30 | 2017-07-25 | Immune Design Corp. | Materials and methods for producing improved lentiviral vector particles |
| WO2013149167A1 (en) * | 2012-03-30 | 2013-10-03 | Immune Design Corp. | Lentiviral vector particles having improved transduction efficiency for cells expressing dc- sign |
| US8323662B1 (en) * | 2012-03-30 | 2012-12-04 | Immune Design Corp. | Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| EP2943203A4 (en) * | 2013-01-11 | 2016-08-24 | Scripps Research Inst | METHOD AND COMPOSITIONS FOR INCREASING THE TRANSDUCTION EFFICIENCY OF RETROVIRAL VECTORS |
| GB201308772D0 (en) * | 2013-05-15 | 2013-06-26 | Imp Innovations Ltd | Vectors |
| SMT202000531T1 (it) | 2014-03-09 | 2020-11-10 | Univ Pennsylvania | Composizioni utili in trattamento di deficit di ornitina transcarbamilasi(otc) |
| KR20170032373A (ko) | 2014-07-15 | 2017-03-22 | 이뮨 디자인 코포레이션 | Tlr4 작용제 보조제 및 렌티바이러스 벡터를 이용한 프라임-부스트 요법 |
| WO2016118715A1 (en) * | 2015-01-21 | 2016-07-28 | Cornell University | Viral vectors for prophylaxis and therapy of hemoglobinopathies |
| US20180112180A1 (en) * | 2015-01-26 | 2018-04-26 | Fate Therapeutics, Inc. | Cells with increased immuno-regulatory properties and methods for their use and manufacture |
| CN114262380A (zh) | 2015-03-18 | 2022-04-01 | 欧姆尼赛特有限公司 | 包含经修饰的α病毒表面糖蛋白与肿瘤相关抗原的融合蛋白及其方法 |
| DK3283658T3 (da) | 2015-05-18 | 2020-05-18 | Calimmune Inc | Fremgangsmåder til at diskriminere mellem HIV-1 og lentivirus-vektorer |
| US20190119350A1 (en) | 2015-09-09 | 2019-04-25 | Immune Design Corp. | Ny-eso-1 specific tcrs and methods of use thereof |
| WO2017083291A1 (en) * | 2015-11-09 | 2017-05-18 | Immune Design Corp. | Compositions comprising lentiviral vectors expressing il-12 and methods of use thereof |
| AU2016354102B2 (en) | 2015-11-09 | 2022-05-12 | Immune Design Corp. | A retroviral vector for the administration and expression of replicon RNA expressing heterologous nucleic acids |
| JP2019509275A (ja) * | 2016-02-23 | 2019-04-04 | イミューン デザイン コーポレイション | マルチゲノムレトロウイルスベクター調製物ならびにそれらを産生および使用するための方法およびシステム |
| WO2017152042A2 (en) * | 2016-03-04 | 2017-09-08 | New York University | Virus vectors expressing multiple epitopes of tumor associated antigens for inducing antitumor immunity |
| MX2018012472A (es) | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| EP3235908A1 (en) | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
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