BR112014005873A2 - enzimas, constructo de dna, vetor de expressão, célula, preparação, composição, uso e produto - Google Patents

enzimas, constructo de dna, vetor de expressão, célula, preparação, composição, uso e produto

Info

Publication number
BR112014005873A2
BR112014005873A2 BR112014005873A BR112014005873A BR112014005873A2 BR 112014005873 A2 BR112014005873 A2 BR 112014005873A2 BR 112014005873 A BR112014005873 A BR 112014005873A BR 112014005873 A BR112014005873 A BR 112014005873A BR 112014005873 A2 BR112014005873 A2 BR 112014005873A2
Authority
BR
Brazil
Prior art keywords
enzymes
cell
preparation
composition
product
Prior art date
Application number
BR112014005873A
Other languages
English (en)
Other versions
BR112014005873B1 (pt
Inventor
Frisbaek Sorensen Jens
Brond Miller Lone
Original Assignee
Dupont Nutrition Biosci Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Nutrition Biosci Aps filed Critical Dupont Nutrition Biosci Aps
Publication of BR112014005873A2 publication Critical patent/BR112014005873A2/pt
Publication of BR112014005873B1 publication Critical patent/BR112014005873B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12H—PASTEURISATION, STERILISATION, PRESERVATION, PURIFICATION, CLARIFICATION OR AGEING OF ALCOHOLIC BEVERAGES; METHODS FOR ALTERING THE ALCOHOL CONTENT OF FERMENTED SOLUTIONS OR ALCOHOLIC BEVERAGES
    • C12H1/00—Pasteurisation, sterilisation, preservation, purification, clarification, or ageing of alcoholic beverages
    • C12H1/12—Pasteurisation, sterilisation, preservation, purification, clarification, or ageing of alcoholic beverages without precipitation
    • C12H1/14—Pasteurisation, sterilisation, preservation, purification, clarification, or ageing of alcoholic beverages without precipitation with non-precipitating compounds, e.g. sulfiting; Sequestration, e.g. with chelate-producing compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/248—Xylanases
    • C12N9/2482—Endo-1,4-beta-xylanase (3.2.1.8)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
    • C12C11/00—Fermentation processes for beer
    • C12C11/003—Fermentation of beerwort
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
    • C12C12/00—Processes specially adapted for making special kinds of beer
    • C12C12/002—Processes specially adapted for making special kinds of beer using special microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01008—Endo-1,4-beta-xylanase (3.2.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • D—TEXTILES; PAPER
    • D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21H—PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
    • D21H17/00—Non-fibrous material added to the pulp, characterised by its constitution; Paper-impregnating material characterised by its constitution
    • D21H17/005—Microorganisms or enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fodder In General (AREA)
  • General Preparation And Processing Of Foods (AREA)
BR112014005873-3A 2011-09-14 2012-09-14 Composição, uso de uma composição, método de alteração da filtrabilidade, método de redução da pressão acumulada, método para a produção de um alimento, método para a produção de uma pasta de brassagem e método para a produção de um biocombustível BR112014005873B1 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161534574P 2011-09-14 2011-09-14
EP11181241 2011-09-14
US61/534,574 2011-09-14
EP11181241.8 2011-09-14
US201261676535P 2012-07-27 2012-07-27
US61/676,535 2012-07-27
PCT/EP2012/068041 WO2013037933A2 (en) 2011-09-14 2012-09-14 Enzymes

Publications (2)

Publication Number Publication Date
BR112014005873A2 true BR112014005873A2 (pt) 2018-08-07
BR112014005873B1 BR112014005873B1 (pt) 2021-11-16

Family

ID=47883847

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014005873-3A BR112014005873B1 (pt) 2011-09-14 2012-09-14 Composição, uso de uma composição, método de alteração da filtrabilidade, método de redução da pressão acumulada, método para a produção de um alimento, método para a produção de uma pasta de brassagem e método para a produção de um biocombustível

Country Status (15)

Country Link
US (2) US9683224B2 (pt)
EP (2) EP2756078B9 (pt)
JP (1) JP6084617B2 (pt)
CN (2) CN106434246A (pt)
AR (1) AR087885A1 (pt)
AU (1) AU2012307299C1 (pt)
BR (1) BR112014005873B1 (pt)
DK (1) DK2756078T3 (pt)
EA (2) EA027084B1 (pt)
ES (1) ES2645921T3 (pt)
HU (1) HUE037237T2 (pt)
MX (1) MX353745B (pt)
PL (1) PL2756078T3 (pt)
WO (1) WO2013037933A2 (pt)
ZA (1) ZA201400889B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150337247A1 (en) * 2012-08-03 2015-11-26 Dupont Nutrition Biosciences Aps Enzymes
EP2994529B1 (en) 2013-05-10 2018-11-21 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
BR112016002045A2 (pt) 2013-07-29 2017-08-29 Danisco Us Inc Variantes de enzimas
EP3017706A1 (en) 2014-11-05 2016-05-11 Dupont Nutrition Biosciences ApS Enzymes for malting
CN106906198B (zh) * 2015-12-23 2019-12-13 东莞泛亚太生物科技有限公司 提升耐温性的纤维素酶
CA3010581C (en) * 2016-02-18 2023-06-27 Biopract Gmbh Arabinanase and uses thereof
DK3419991T3 (da) 2016-03-04 2023-01-16 Danisco Us Inc Modificerede ribosomale genpromotorer til proteinproduktion i mikroorganismer
US20180072972A1 (en) * 2016-09-09 2018-03-15 Alpha Revolution, Inc. Systems, devices and methods for fermenting beverages
WO2019089898A1 (en) 2017-11-02 2019-05-09 Danisco Us Inc Freezing point depressed solid matrix compositions for melt granulation of enzymes
CN110714037A (zh) * 2019-11-29 2020-01-21 江南大学 一种木聚糖酶的制备方法及其在啤酒生产中的应用
CN116286751B (zh) * 2023-05-15 2023-07-25 北京市科学技术研究院 催化效率提高的双功能纤维素酶突变体及其应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD282028A5 (de) * 1989-02-16 1990-08-29 Akad Wissenschaften Ddr Verfahren zur herstellung einer thermostabilen, hybriden bacillus-beta-1,3-1,4-glukanase
ES2202320T3 (es) 1992-12-23 2004-04-01 Novozymes A/S Enzima con actividad de endoglucanasa.
NZ259372A (en) * 1992-12-24 1996-09-25 Gist Brocades Nv Cloning and expression of xylanase-b
ES2316882T3 (es) 1993-03-10 2009-04-16 Novozymes A/S Enzimas de aspergillus aculeatus con una actividad xilanasa.
EP0759073A1 (en) 1994-05-11 1997-02-26 Novo Nordisk A/S AN ENZYME WITH ENDO-1,3(4)-$g(b)-GLUCANASE ACTIVITY
AU7294396A (en) * 1995-10-13 1997-04-30 Gist-Brocades B.V. Protein detection
JP2000510336A (ja) 1996-05-03 2000-08-15 ギスト ブロカデス ベスローテン フェンノートシャップ 改善された濾過性及び／又は増加した収率を有する麦汁の製造方法
EA000002B1 (ru) 1996-05-07 1997-09-30 Владимир Михайлович Шемякин Алкогольный напиток и способ его получения
CN1230225A (zh) * 1996-08-05 1999-09-29 莫根国际股份有限公司 使用转基因麦芽种生产酒精性饮料的改进工艺
US6103511A (en) * 1996-10-04 2000-08-15 University Of Georgia Research Foundation, Inc. Lichenase and coding sequences
WO1998028410A1 (en) 1996-12-20 1998-07-02 Novo Nordisk A/S A novel endoglucanase
EP0976838A1 (en) 1998-05-06 2000-02-02 Rhone-Poulenc Nutrition Animale Enzymes mixture
EP1142491A3 (en) * 2000-04-06 2002-04-03 Kyowa Hakko Kogyo Co., Ltd. Method of removing off-flavor from foods and deodorizer
EP1613729A1 (en) 2003-04-04 2006-01-11 Novozymes A/S Mash viscosity reduction
CN103484486B (zh) * 2003-07-02 2018-04-24 维莱尼姆公司 葡聚糖酶，编码它们的核酸以及制备和使用它们的方法
DE10358535A1 (de) * 2003-12-13 2005-07-14 Henkel Kgaa Hybridenzyme mit kationischer Bindedomäne
CN1918277A (zh) * 2003-12-19 2007-02-21 诺维信公司 糖化工艺
EP1735454B1 (en) 2004-03-25 2017-05-10 Novozymes, Inc. Methods for degrading or converting plant cell wall polysaccharides
CN1942705A (zh) 2004-04-13 2007-04-04 萨夫配件有限责任公司 用于热水龙头的产生彩色液体流的方法及装置
EP1812547A1 (en) 2004-06-03 2007-08-01 Novozymes A/S Mashing process and enzyme composition useful therein
US20090117630A1 (en) 2004-12-22 2009-05-07 Novozymes A/S Fermentation product processes
CA2605258C (en) 2005-04-26 2016-01-05 Novozymes A/S Hydrolysis of arabinoxylan
WO2007056321A1 (en) 2005-11-08 2007-05-18 Novozymes North America, Inc. Dewatering whole stillage
USRE45660E1 (en) * 2006-02-14 2015-09-01 Bp Corporation North America Inc. Xylanases, nucleic acids encoding them and methods for making and using them
WO2008023060A1 (en) 2006-08-25 2008-02-28 Novozymes A/S Fermentation process
CN102016041A (zh) * 2008-02-29 2011-04-13 中央佛罗里达大学研究基金会有限公司 植物降解材料的合成和应用
GB0805360D0 (en) * 2008-03-25 2008-04-30 Univ Leuven Kath Arabinoxylan oligosaccharide preparation
US8518684B2 (en) 2008-11-18 2013-08-27 Novozymes, Inc. Methods and compositions for degrading cellulosic material
EP2382310B1 (en) 2008-12-23 2016-08-24 DuPont Nutrition Biosciences ApS Polypeptides with xylanase activity
CN102317451A (zh) 2008-12-23 2012-01-11 丹尼斯科公司 具有木聚糖酶活性的多肽
KR20110104539A (ko) 2008-12-23 2011-09-22 대니스코 에이/에스 자일라나제 활성을 갖는 폴리펩타이드
JP2010148485A (ja) * 2008-12-26 2010-07-08 Kirin Brewery Co Ltd フェルラ酸高含有発酵アルコール飲料
JP5876823B2 (ja) * 2009-05-07 2016-03-02 デュポン ニュートリション バイオサイエンシーズ エーピーエスＤｕＰｏｎｔ Ｎｕｔｒｉｔｉｏｎ Ｂｉｏｓｃｉｅｎｃｅｓ ＡｐＳ 酵素複合体

Also Published As

Publication number Publication date
EP2756078A2 (en) 2014-07-23
PL2756078T3 (pl) 2017-12-29
BR112014005873B1 (pt) 2021-11-16
EP2756078B9 (en) 2018-09-12
EA201490624A1 (ru) 2014-06-30
WO2013037933A2 (en) 2013-03-21
JP2014527813A (ja) 2014-10-23
EP3061816A1 (en) 2016-08-31
AR087885A1 (es) 2014-04-23
DK2756078T3 (da) 2017-11-27
US9683224B2 (en) 2017-06-20
US20170314004A1 (en) 2017-11-02
AU2012307299B2 (en) 2018-03-22
HUE037237T2 (hu) 2018-08-28
ES2645921T3 (es) 2017-12-11
EA027084B1 (ru) 2017-06-30
EA201790153A3 (ru) 2017-09-29
CN106434246A (zh) 2017-02-22
EP2756078B1 (en) 2017-08-16
AU2012307299A1 (en) 2014-02-20
EA201790153A2 (ru) 2017-06-30
AU2012307299C1 (en) 2018-10-25
JP6084617B2 (ja) 2017-02-22
MX353745B (es) 2018-01-26
US20140329283A1 (en) 2014-11-06
CN103814129A (zh) 2014-05-21
WO2013037933A3 (en) 2013-05-30
MX2014002950A (es) 2014-07-09
ZA201400889B (en) 2017-06-28

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