BR112016002045A2 - Variantes de enzimas - Google Patents
Variantes de enzimasInfo
- Publication number
- BR112016002045A2 BR112016002045A2 BR112016002045A BR112016002045A BR112016002045A2 BR 112016002045 A2 BR112016002045 A2 BR 112016002045A2 BR 112016002045 A BR112016002045 A BR 112016002045A BR 112016002045 A BR112016002045 A BR 112016002045A BR 112016002045 A2 BR112016002045 A2 BR 112016002045A2
- Authority
- BR
- Brazil
- Prior art keywords
- variants
- glycosyl hydrolase
- methods
- glycosyl
- enzyme variants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
Abstract
VARIANTE DE ENZIMA PARENTAL GH61, POLINUCLEOTÍDEO, VETOR, CÉLULA HOSPEDEIRA, COMPOSIÇÃO, MÉTODO DE PRODUÇÃO DE UM POLIPEPTÍDEO VARIANTE GH61, MÉTODO PARA HIDROLISAR UM SUBSTRATO CELULÓSICO E MÉTODO DE PRODUÇÃO DE ETANOL. A presente invenção refere-se a variantes de enzimas glicosil hidrolases, em particular variantes de certas oxidorredutases da família 61 de glicosil hidrolase. Os ácidos nucleicos que codificam as variantes de glicosil hidrolase, composições incluindo as variantes de glicosil hidrolase, métodos de produção das variantes e métodos de uso das variantes são também descritos.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361859721P | 2013-07-29 | 2013-07-29 | |
US201361859630P | 2013-07-29 | 2013-07-29 | |
US201361859704P | 2013-07-29 | 2013-07-29 | |
US201361859680P | 2013-07-29 | 2013-07-29 | |
US201361859666P | 2013-07-29 | 2013-07-29 | |
US201361859735P | 2013-07-29 | 2013-07-29 | |
US201361859712P | 2013-07-29 | 2013-07-29 | |
PCT/US2014/048067 WO2015017254A1 (en) | 2013-07-29 | 2014-07-24 | Variant enzymes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016002045A2 true BR112016002045A2 (pt) | 2017-08-29 |
Family
ID=51299060
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016002045A BR112016002045A2 (pt) | 2013-07-29 | 2014-07-24 | Variantes de enzimas |
BR112016002067A BR112016002067A2 (pt) | 2013-07-29 | 2014-07-24 | Variantes de enzimas |
BR112016002038A BR112016002038A2 (pt) | 2013-07-29 | 2014-07-24 | Variantes de enzimas |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016002067A BR112016002067A2 (pt) | 2013-07-29 | 2014-07-24 | Variantes de enzimas |
BR112016002038A BR112016002038A2 (pt) | 2013-07-29 | 2014-07-24 | Variantes de enzimas |
Country Status (10)
Country | Link |
---|---|
US (4) | US10167460B2 (pt) |
EP (3) | EP3027741B1 (pt) |
JP (3) | JP2016533741A (pt) |
CN (3) | CN105916981A (pt) |
AU (3) | AU2014296572A1 (pt) |
BR (3) | BR112016002045A2 (pt) |
DK (2) | DK3027742T3 (pt) |
MX (3) | MX2016001317A (pt) |
WO (3) | WO2015017255A1 (pt) |
ZA (3) | ZA201600633B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2012116081A (ru) | 2009-09-23 | 2013-10-27 | ДАНИСКО ЮЭс ИНК. | Новые гликозилгидролазные ферменты и их применения |
EP2516663B1 (en) | 2009-12-23 | 2020-02-12 | Danisco US Inc. | Methods for improving the efficiency of simultaneous saccharification and fermentation reactions |
CA2830508A1 (en) | 2011-03-17 | 2012-09-20 | Danisco Us Inc. | Method for reducing viscosity in saccharification process |
DK3027742T3 (da) | 2013-07-29 | 2020-02-24 | Danisco Us Inc | Enzymvarianter |
WO2016138315A1 (en) | 2015-02-25 | 2016-09-01 | Danisco Us Inc | Alpha-glucosidase, compositions & methods |
JP6914250B2 (ja) | 2015-09-02 | 2021-08-04 | デュポン ニュートリション バイオサイエンシス エーピーエス | 動物における病原性感染症を予防および/または治療する際のグリコシドヒドラーゼおよびそれらの使用 |
KR20190018512A (ko) | 2016-06-15 | 2019-02-22 | 코덱시스, 인코포레이티드 | 조작된 베타-글루코시다아제 및 글루코실화 방법 |
WO2018005225A1 (en) | 2016-06-30 | 2018-01-04 | Danisco Us Inc | Aspartic proteases |
WO2018053058A1 (en) | 2016-09-14 | 2018-03-22 | Danisco Us Inc. | Lignocellulosic biomass fermentation-based processes |
JP2019534691A (ja) | 2016-09-23 | 2019-12-05 | デュポン ニュートリション バイオサイエンシス エーピーエス | デンプンの消化を促進するための、反芻動物用の飼料添加物としての、低pH活性アルファ−1,4;/1,6−グリコシドヒドロラーゼの使用 |
WO2018106656A1 (en) * | 2016-12-06 | 2018-06-14 | Danisco Us Inc | Truncated lpmo enzymes and use thereof |
EP3555301B1 (en) | 2016-12-15 | 2020-09-09 | Danisco US Inc. | Method for increasing the production of ethanol from corn fiber in a starch hydrolysis process by using gh31 alpha-glucosidases |
US20190330577A1 (en) | 2016-12-21 | 2019-10-31 | Dupont Nutrition Biosciences Aps | Methods of using thermostable serine proteases |
ES2680196B1 (es) * | 2017-02-01 | 2019-07-30 | Abengoa Bioenergia Nuevas Tecnologias Sa | Polipeptidos con actividad polisacarido monooxigenasa y su usopara la produccion de azucares fermentables |
BR112019018381A2 (pt) | 2017-03-06 | 2020-04-07 | Dupont Nutrition Biosci Aps | fucosidases fúngicas e seu uso na prevenção e/ou no tratamento de uma infecção patogênica em um animal |
WO2019074828A1 (en) | 2017-10-09 | 2019-04-18 | Danisco Us Inc | CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE |
CN111989400A (zh) | 2017-11-14 | 2020-11-24 | 丹尼斯科美国公司 | α-淀粉酶、组合物和方法 |
PE20211298A1 (es) | 2017-12-19 | 2021-07-20 | Dupont Nutrition Biosci Aps | Modificacion enzimatica mejorada de fosfolipidos en alimentos |
MX2021010234A (es) | 2019-02-25 | 2021-12-10 | Dupont Nutrition Biosci Aps | Hidrolizados proteicos con mayor rendimiento de aminoácido n-terminal. |
CN110747212B (zh) * | 2019-11-29 | 2022-05-17 | 怀化学院 | 一种新果胶酶的基因及其蛋白表达、载体和应用 |
CN110846332B (zh) * | 2019-11-29 | 2022-05-17 | 怀化学院 | 一种果胶酶人工序列及其表达方法和应用 |
CN110846294B (zh) * | 2019-11-29 | 2022-05-17 | 怀化学院 | 重组果胶酶及其基因、重组载体、制备方法和应用 |
CN111154743B (zh) * | 2020-04-01 | 2021-01-05 | 黑龙江省农业科学院畜牧兽医分院 | 突变型纤维素酶及其在玉米青贮中的应用 |
WO2022266456A2 (en) | 2021-06-18 | 2022-12-22 | Dupont Nutrition Biosciences Aps | Proteases for beer haze reduction |
CN113913412B (zh) * | 2021-10-13 | 2023-10-03 | 湖北大学 | 蛋白酶k突变体及其制备方法 |
CN114480146B (zh) * | 2022-04-15 | 2022-06-24 | 中国科学院天津工业生物技术研究所 | 一种米曲霉菌株在富集铜铁锰锌中的应用 |
WO2024015974A1 (en) | 2022-07-15 | 2024-01-18 | Dupont Nutrition Biosciences Aps | Improved enzymatic modification of phospholipids in food |
WO2024064653A1 (en) | 2022-09-20 | 2024-03-28 | Dupont Nutrition Biosciences Aps | Variant anti-viral polypeptides |
CN116121434B (zh) * | 2022-09-26 | 2023-12-12 | 四川农业大学 | 一种控制小麦zip3a锌转运功能的氨基酸位点及分子标记 |
Family Cites Families (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1368599A (en) | 1970-09-29 | 1974-10-02 | Unilever Ltd | Softening compositions |
GB1358599A (en) | 1970-12-22 | 1974-07-03 | Monacelli Umberto | Gun for firing tacks |
DK187280A (da) | 1980-04-30 | 1981-10-31 | Novo Industri As | Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode |
GB2095275B (en) | 1981-03-05 | 1985-08-07 | Kao Corp | Enzyme detergent composition |
GB2094826B (en) | 1981-03-05 | 1985-06-12 | Kao Corp | Cellulase enzyme detergent composition |
CA1338400C (en) | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
EP0406314B1 (en) | 1988-03-24 | 1993-12-01 | Novo Nordisk A/S | A cellulase preparation |
US5776757A (en) | 1988-03-24 | 1998-07-07 | Novo Nordisk A/S | Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof |
DK115890D0 (da) | 1990-05-09 | 1990-05-09 | Novo Nordisk As | Enzym |
DE69133352T2 (de) | 1990-10-05 | 2004-11-04 | Genencor International, Inc., Palo Alto | Methoden zur behandlung baumwolle-enthaltender fasern mit zellulase |
US5246853A (en) | 1990-10-05 | 1993-09-21 | Genencor International, Inc. | Method for treating cotton-containing fabric with a cellulase composition containing endoglucanase components and which composition is free of exo-cellobiohydrolase I |
US5475101A (en) | 1990-10-05 | 1995-12-12 | Genencor International, Inc. | DNA sequence encoding endoglucanase III cellulase |
FI932521A0 (fi) | 1993-06-02 | 1993-06-02 | Alko Ab Oy | Nytt endoglukanasenzym |
US5861271A (en) | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
US6268196B1 (en) | 1993-12-17 | 2001-07-31 | Genencor International, Inc. | Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions |
US7005128B1 (en) | 1993-12-17 | 2006-02-28 | Genencor International, Inc. | Enzyme feed additive and animal feed including it |
AU7626196A (en) | 1995-11-27 | 1997-06-19 | Unilever N.V. | Enzymatic detergent compositions |
TW552268B (en) | 1997-10-08 | 2003-09-11 | Yun-Ru Chen | Chimeric proteins with a cellulose binding domain (CBD) |
AR016969A1 (es) * | 1997-10-23 | 2001-08-01 | Procter & Gamble | VARIANTE DE PROTEASA, ADN, VECTOR DE EXPRESIoN, MICROORGANISMO HUESPED, COMPOSICIoN DE LIMPIEZA, ALIMENTO PARA ANIMALES Y COMPOSICIoN PARA TRATAR UN TEXTIL |
JP2002176979A (ja) | 2000-12-12 | 2002-06-25 | Gencom Co | セルロース結合ドメインを細胞表層に提示する形質転換酵母 |
US7045331B2 (en) | 2001-12-18 | 2006-05-16 | Genencor International, Inc. | EGVII endoglucanase and nucleic acids encoding the same |
MXPA04011011A (es) * | 2002-05-14 | 2005-02-14 | Novozymes As | Variantes de pectato liasa. |
GB2389584A (en) | 2002-06-14 | 2003-12-17 | Norsk Hydro As | A fusion protein |
DK2295559T3 (en) | 2002-08-16 | 2015-12-14 | Danisco Us Inc | Hitherto UNKNOWN HYPROCREA JECORINA CBH1 CELLULASE VARIETY WITH INCREASED THERMAL STABILITY COMPREHENSIVE SUBSTITUTION OR DELETION AT POSITION T255 |
US7273738B2 (en) * | 2002-10-01 | 2007-09-25 | Novozymes A/S | Family GH-61 polypeptides |
WO2005030998A2 (en) | 2003-09-25 | 2005-04-07 | Novozymes Inc. | Methods for monitoring gene expression in filamentous fungal cells |
CN104726431B (zh) | 2004-01-30 | 2018-06-01 | 诺维信股份有限公司 | 具有分解纤维增强活性的多肽及其编码多核苷酸 |
JP5015610B2 (ja) | 2004-02-06 | 2012-08-29 | ノボザイムス,インコーポレイティド | セルロース分解増強活性を有するポリペプチド及びそれをコードするポリヌクレオチド |
US7413887B2 (en) | 2004-05-27 | 2008-08-19 | Genecor International, Inc. | Trichoderma reesei glucoamylase and homologs thereof |
US7781191B2 (en) | 2005-04-12 | 2010-08-24 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
EP1869202B1 (en) | 2005-04-12 | 2018-02-14 | E. I. du Pont de Nemours and Company | Treatment of biomass to obtain fermentable sugars |
FR2885365B1 (fr) | 2005-05-04 | 2007-06-08 | Adisseo France Sas Soc Par Act | Gene abfb-2 de penicillium funiculosum |
CN101321857A (zh) | 2005-09-30 | 2008-12-10 | 诺维信股份有限公司 | 用于增强纤维素材料降解或转化的方法 |
BRPI0707753A2 (pt) | 2006-02-13 | 2011-05-10 | Donaldson Co Inc | trama de filtro compreendendo fibra fina e particulando reativo, adsortivo ou absortivo |
CA2698765A1 (en) | 2007-09-07 | 2009-03-19 | Danisco Us Inc. | Beta-glucosidase enhanced filamentous fungal whole cellulase compositions and methods of use |
JP2009085831A (ja) | 2007-10-01 | 2009-04-23 | Canon Inc | 捕捉体部材及びバイオセンサー素子 |
EP2479265B1 (en) | 2007-10-09 | 2014-06-11 | Danisco US Inc. | Glucoamylase variants with altered properties |
RU2378372C2 (ru) | 2008-03-03 | 2010-01-10 | ООО НПК "Фермтек" | Генетическая конструкция для обеспечения экспрессии целевых гомологичных и гетерологичных генов в клетках мицелиального гриба penicillium verruculosum, используемого в качестве хозяина, способ получения штамма гриба penicillium verruculosum и способ получения ферментного препарата |
CN101978050A (zh) | 2008-03-21 | 2011-02-16 | 丹尼斯科美国公司 | 用于增加生物量水解的富含半纤维素酶的组合物 |
CA2722189A1 (en) | 2008-04-21 | 2009-10-29 | Chromatin, Inc. | Methods and materials for processing a feedstock |
WO2009138877A2 (en) | 2008-05-11 | 2009-11-19 | Universiteit Stellenbosch | Heterologous expression of fungal cellobiohydrolases in yeast |
JP5507062B2 (ja) | 2008-06-16 | 2014-05-28 | 月桂冠株式会社 | 高発現プロモーター |
US8658398B2 (en) | 2008-07-07 | 2014-02-25 | Mascoma Corporation | Heterologous expression of termite cellulases yeast |
JP2010046034A (ja) | 2008-08-22 | 2010-03-04 | Toyota Central R&D Labs Inc | 変異体のスクリーニング方法 |
US8104512B2 (en) | 2008-09-25 | 2012-01-31 | Masco Corporation Of Indiana | Spout tip retention method |
EP2358872A2 (en) | 2008-11-18 | 2011-08-24 | Novozymes Inc. | Methods and compositions for degrading cellulosic material |
US9506046B2 (en) | 2008-11-20 | 2016-11-29 | Novozymes, Inc. | Polypeptides having amylolytic enhancing activity and polynucleotides encoding same |
EP2358878B1 (en) | 2008-11-20 | 2014-10-15 | Novozymes Inc. | Polypeptides having amylolytic enhancing activity and polynucleotides encoding same |
WO2010080407A2 (en) | 2008-12-19 | 2010-07-15 | Novozymes, Inc. | Methods for increasing hydrolysis of cellulosic material |
DK2379712T3 (en) | 2008-12-19 | 2017-05-08 | Novozymes Inc | Methods for Increasing Hydrolysis of Cellulosic Material in the Presence of Cellobiose Dehydrogenase |
WO2010080408A2 (en) | 2008-12-19 | 2010-07-15 | Novozymes, Inc. | Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase |
FI122028B (fi) * | 2008-12-30 | 2011-07-29 | Ab Enzymes Oy | Sieniperäiset endoglukanaasit, niiden tuotto ja käyttö |
KR20110124242A (ko) | 2009-02-20 | 2011-11-16 | 다니스코 유에스 인크. | 발효 브로쓰 제형물 |
CN102333865A (zh) * | 2009-02-27 | 2012-01-25 | 埃欧金能源公司 | 新的木质素抗性纤维素酶 |
WO2010138754A1 (en) | 2009-05-29 | 2010-12-02 | Novozymes, Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
CN104862293A (zh) | 2009-06-03 | 2015-08-26 | 丹尼斯科美国公司 | 具有改善的表达、活性和/或稳定性的纤维素酶变体,及其用途 |
BR112012000078A2 (pt) | 2009-07-03 | 2017-03-01 | Dsm Ip Assets Bv | cepas de talaromyces e composições de enzima. |
EA023194B1 (ru) * | 2009-08-19 | 2016-05-31 | Даниско А/С | Варианты глюкоамилазы |
RU2012116081A (ru) | 2009-09-23 | 2013-10-27 | ДАНИСКО ЮЭс ИНК. | Новые гликозилгидролазные ферменты и их применения |
US20110086236A1 (en) | 2009-10-13 | 2011-04-14 | The Penn State Research Foundation | Composites containing polypeptides attached to polysaccharides and molecules |
DK2602317T3 (da) | 2009-11-20 | 2017-11-13 | Danisco Us Inc | Beta-glucosidasevarianter med forbedrede egenskaber |
BR112012013468A2 (pt) | 2009-12-04 | 2016-05-17 | Georgia Tech Res Inst | processo para tratar uma carga de alimentação compreendendo holocelulose, e, composição adequada para reduzir a cristalinidade da celulose |
EP2516663B1 (en) | 2009-12-23 | 2020-02-12 | Danisco US Inc. | Methods for improving the efficiency of simultaneous saccharification and fermentation reactions |
DK2529013T3 (en) * | 2010-01-28 | 2016-09-12 | Academia Sinica | Novel beta-glucosidase and uses thereof |
BR112012020804A2 (pt) | 2010-02-11 | 2015-09-15 | Iogen Energy Corp | módulos de ligação de carboidrato com ligação reduzida à lignina |
FR2957922A1 (fr) | 2010-03-26 | 2011-09-30 | Inst Francais Du Petrole | Nouvelles proteines de fusion cbh1-eg1 et leur utilisation |
DK2588603T3 (en) | 2010-06-29 | 2017-07-03 | Dsm Ip Assets Bv | POLYPEPTIDE THAT HAS OR CONTRIBUTES TO CARBOHYDRATE MATERIAL DEGRADING ACTIVITIES AND APPLICATIONS THEREOF |
EP2591119B2 (en) | 2010-07-07 | 2022-09-28 | Novozymes North America, Inc. | Fermentation process with GH61 polypeptides |
CN107435058A (zh) | 2010-08-06 | 2017-12-05 | 诺维信公司 | 降解或水解多糖的方法 |
US9458483B2 (en) | 2010-08-12 | 2016-10-04 | Novozymes, Inc. | Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof |
JP5810489B2 (ja) | 2010-08-20 | 2015-11-11 | 株式会社豊田中央研究所 | セルラーゼ活性を有するタンパク質及びその利用 |
US9493802B2 (en) * | 2010-08-20 | 2016-11-15 | Codexis, Inc. | Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose |
JP2013539971A (ja) | 2010-09-15 | 2013-10-31 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | Trichodermareeseiのエンドグルカナーゼiの好熱性変異体 |
MX2013003236A (es) | 2010-09-30 | 2013-05-30 | Novozymes Inc | Variantes de polipeptidos que tienen actividad potenciadora celulolitica y polinucleotidos que codifican a los mismos. |
DK2635671T3 (en) | 2010-11-02 | 2016-10-24 | Codexis Inc | Improved fungi strains |
DK2640833T3 (en) | 2010-11-18 | 2016-11-28 | Novozymes Inc | Chimeric polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM |
US9399764B2 (en) | 2010-11-24 | 2016-07-26 | Novartis International Pharmaceutical, Ltd. | Fusion enzymes |
KR20130131417A (ko) | 2010-12-28 | 2013-12-03 | 니뽄 다바코 산교 가부시키가이샤 | 개변형 타마비딘 |
GB2487299B (en) | 2011-01-13 | 2013-09-18 | Echogen Inc | Method of performing a site-specific chiral inversion in a tripeptide |
BR112013023737A2 (pt) | 2011-03-17 | 2016-12-13 | Danisco Us Inc | enzimas de glicosil hidrolase e utilização das mesmas para a hidrólise de biomassa |
CA2830508A1 (en) | 2011-03-17 | 2012-09-20 | Danisco Us Inc. | Method for reducing viscosity in saccharification process |
BR112013023715A2 (pt) * | 2011-03-17 | 2016-09-13 | Danisco Us Inc | "polipeptídeo, polinucleotídeo, vetor, célula hospedeira, e composição para uso em hidrólise de biomassa, bem como métodos para hidrolisar material de biomassa celulósica e para produzir composição de mistura de cultura ou caldo de fermentação" |
WO2012135719A1 (en) | 2011-03-31 | 2012-10-04 | Novozymes, Inc. | Cellulose binding domain variants and polynucleotides encoding same |
CA2831954A1 (en) | 2011-04-04 | 2012-10-11 | The Regents Of The University Of California | Enhanced cellulose degradation |
CA2835606A1 (en) | 2011-04-07 | 2012-10-11 | Synaptic Research, Llc | Single chain antibodies for photosynthetic microorganisms and methods of use |
DK2702162T3 (da) | 2011-04-29 | 2020-05-18 | Novozymes Inc | Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale |
BR112014004171A2 (pt) | 2011-08-22 | 2018-11-06 | Codexis Inc | variantes da proteína glicósideo hidrolase gh61 e cofatores que aumentam a atividade de gh61 |
EP2748314B1 (en) | 2011-08-24 | 2016-12-28 | Novozymes, Inc. | Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof |
US9279163B2 (en) | 2011-08-31 | 2016-03-08 | Iogen Energy Corporation | Cellobiohydrolase enzymes |
EA027084B1 (ru) | 2011-09-14 | 2017-06-30 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Ферменты |
US10351834B2 (en) * | 2011-11-21 | 2019-07-16 | Novozymes, Inc. | GH61 polypeptide variants and polynucleotides encoding same |
WO2013110242A1 (en) | 2012-01-29 | 2013-08-01 | Novozymes A/S | Methods for degrading or converting cellulosic material |
KR102064025B1 (ko) | 2012-04-17 | 2020-01-08 | 에프. 호프만-라 로슈 아게 | 수식된 핵산을 사용하는 폴리펩티드의 발현 방법 |
US20130280764A1 (en) | 2012-04-19 | 2013-10-24 | Dyadic International (Usa) Ltd. | Method of improving the activity of cellulase enzyme mixtures in the saccharification (ligno)cellulosic material |
CA2868308A1 (en) | 2012-04-27 | 2013-10-31 | Novozymes, Inc. | Gh61 polypeptide variants and polynucleotides encoding same |
WO2013177714A1 (en) | 2012-05-31 | 2013-12-05 | Iogen Energy Corporation | Cellulose-degrading enzyme composition comprising gh16 |
EA201590312A1 (ru) | 2012-08-03 | 2015-10-30 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Ферменты |
EP2898068A2 (en) * | 2012-09-19 | 2015-07-29 | Novozymes, Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
CA2892021A1 (en) | 2012-11-20 | 2014-05-30 | Pronutria, Inc. | Engineered secreted proteins and methods |
CN103966252A (zh) | 2013-01-28 | 2014-08-06 | 北大工学院绍兴技术研究院 | 纤维素结合域在棒状杆菌分泌表达系统中的应用 |
EP2959004B1 (en) | 2013-02-21 | 2021-01-13 | Novozymes A/S | Methods of saccharifying and fermenting a cellulosic material |
AR096670A1 (es) | 2013-06-21 | 2016-01-27 | Dupont Nutrition Biosci Aps | Método para preparar una composición de aditivos para alimentos para animales |
WO2014202711A1 (en) | 2013-06-21 | 2014-12-24 | Dupont Nutrition Biosciences Aps | Method of preparing feed additive |
WO2015004098A1 (en) | 2013-07-11 | 2015-01-15 | Dsm Ip Assets B.V. | Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars |
DK3027742T3 (da) | 2013-07-29 | 2020-02-24 | Danisco Us Inc | Enzymvarianter |
EP3052620B1 (en) | 2013-09-04 | 2020-07-15 | Novozymes A/S | Processes for increasing enzymatic hydrolysis of cellulosic material |
AU2014324901A1 (en) | 2013-09-25 | 2016-05-19 | Axcella Health Inc. | Compositions and formulations for prevention and treatment of diabetes and obesity, and methods of production and use thereof in glucose and caloric control |
MY186318A (en) | 2014-01-07 | 2021-07-08 | Novozymes As | Process for degrading mannan-containing cellulosic materials |
CA2944957C (en) | 2014-04-30 | 2022-03-29 | Dsm Ip Assets B.V. | Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars |
WO2015175308A1 (en) | 2014-05-13 | 2015-11-19 | Danisco Us Inc. | Improved enzymatic hydrolysis of biomass |
MY183472A (en) | 2014-05-14 | 2021-02-19 | Esteve Labor Dr | Adenoassociated virus vectors for the treatment of lysosomal storage disorders |
EP3180354A1 (en) | 2014-08-15 | 2017-06-21 | Danisco US Inc. | Compositions and methods for improved protein production |
US10793887B2 (en) | 2014-08-21 | 2020-10-06 | Novozymes A/S | Process for saccharifying cellulosic material under oxygen addition |
EP2993230A1 (en) | 2014-09-02 | 2016-03-09 | Clariant Produkte (Deutschland) GmbH | Polypeptides having xylanase activity with a high conversion rate of xylose-containing polysaccharides |
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