BR0317481A - Processo para a produção de produtos farmacêuticos revestidos e de suplementos alimentìcios com gradientes de concentração no revestimento - Google Patents

Processo para a produção de produtos farmacêuticos revestidos e de suplementos alimentìcios com gradientes de concentração no revestimento

Info

Publication number
BR0317481A
BR0317481A BR0317481-6A BR0317481A BR0317481A BR 0317481 A BR0317481 A BR 0317481A BR 0317481 A BR0317481 A BR 0317481A BR 0317481 A BR0317481 A BR 0317481A
Authority
BR
Brazil
Prior art keywords
food supplements
pharmaceutical products
parts
production
substance
Prior art date
Application number
BR0317481-6A
Other languages
English (en)
Inventor
Hans-Ulrich Petereit
Christian Meier
Erna Roth
Original Assignee
Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Gmbh filed Critical Roehm Gmbh
Publication of BR0317481A publication Critical patent/BR0317481A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/24—Cellulose or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/25—Synthetic polymers, e.g. vinylic or acrylic polymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

"PROCESSO PARA A PRODUçãO DE PRODUTOS FARMACêUTICOS REVESTIDOS E DE SUPLEMENTOS ALIMENTìCIOS COM GRADIENTES DE CONCENTRAçãO NO REVESTIMENTO". A presente invenção refere-se a um processo para a produção de produtos farmacêuticos ou de partes dos mesmos ou de suplementos alimentícios ou de partes dos mesmos por aplicação de revestimentos para usos farmacêuticos ou para a utilização como suplementos alimentícios para seres humanos ou animais, com um agente de revestimento de formação de filme misturado com pelo menos uma outra substância adequada para as ditas finalidades citadas. O agente de revestimento formador de filme e a outra substância primeiro constituem partes individuais líquidas, separadas e são borrifadas por meio de pelo menos um dispositivo de spray - que são dotados, individualmente ou em conjunto, pelo menos dois bocais separados para líquidos e têm seus jatos de spray que se sobrepõem - de uma maneira tal que as partes individuais borrifadas pelos bocais separados se misturam durante o processo de borrifação e a mistura forma um revestimento em filme contínuo sobre o substrato, formando o suplemento alimentício, o produto farmacêutico ou parte dos mesmos. A invenção é caracterizada pelo fato de que o agente de revestimento e a outra substância estão em um gradiente de concentração de dentro para fora.
BR0317481-6A 2002-12-20 2003-10-18 Processo para a produção de produtos farmacêuticos revestidos e de suplementos alimentìcios com gradientes de concentração no revestimento BR0317481A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10260919A DE10260919A1 (de) 2002-12-20 2002-12-20 Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug
PCT/EP2003/011540 WO2004058225A1 (de) 2002-12-20 2003-10-18 Verfahren zur herstellung von überzogenen arzneiformen und nahrungsergänzungsmitteln mit konzentrationsgradienten im überzug

Publications (1)

Publication Number Publication Date
BR0317481A true BR0317481A (pt) 2005-11-16

Family

ID=32404270

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317481-6A BR0317481A (pt) 2002-12-20 2003-10-18 Processo para a produção de produtos farmacêuticos revestidos e de suplementos alimentìcios com gradientes de concentração no revestimento

Country Status (11)

Country Link
US (1) US20050271778A1 (pt)
EP (1) EP1572162A1 (pt)
JP (1) JP2006515852A (pt)
KR (1) KR20050088189A (pt)
AU (1) AU2003280390A1 (pt)
BR (1) BR0317481A (pt)
CA (1) CA2509913A1 (pt)
DE (1) DE10260919A1 (pt)
MX (1) MXPA05006285A (pt)
PL (1) PL375917A1 (pt)
WO (1) WO2004058225A1 (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1476138E (pt) 2002-02-21 2012-02-14 Valeant Internat Barbados Srl Formulações de libertação modificada de pelo menos uma forma de tramadol
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
WO2006095819A1 (ja) * 2005-03-10 2006-09-14 Taisho Pharmaceutical Co., Ltd. 糖衣剤
DE102005032806A1 (de) * 2005-07-12 2007-01-18 Röhm Gmbh Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten
SI2051704T1 (sl) * 2006-08-18 2012-08-31 Evonik Roehm Gmbh Farmacevtski sestavek s kontroliranim sproščanjem aktivne učinkovine za aktivne učinkovine z dobro topnostjo v vodi
SI2459634T1 (sl) * 2009-07-30 2017-07-31 Evonik Roehm Gmbh Praškast ali granuliran sestavek, ki vsebuje kopolimer, dikarboksilno kislino in maščobno monokarboksilno kislino
GR1007237B (el) * 2009-12-07 2011-04-08 Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, Νεα διαδικασια παραγωγης σταθερης φαρμακευτικης συνθεσης επικαλυμμενων με γαστροανθεκτικο υμενιο εντεροδιαλυτων δισκιων ακετυλοσαλικυλικου οξεος
SI2627684T1 (sl) * 2010-10-13 2014-10-30 Evonik Roehm Gmbh Postopek priprave kopolimera met(akrilata), ki vsebuje kvaternarne amonijeve skupine s polimerizacijo prostih radikalov v raztopini
US8962064B2 (en) 2011-02-28 2015-02-24 Basf Se Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
EP2681263B1 (de) * 2011-02-28 2018-09-12 Basf Se Herstellung von pulverförmigen überzugsmitteln für stabile protektive überzüge für pharmazeutische dosierungsformen
JP5864513B2 (ja) * 2013-10-31 2016-02-17 進一 上田 焼き菓子の着色装置
US11220582B2 (en) * 2017-03-03 2022-01-11 Harland Medical Systems, Inc. Coating composition comprised of a hydrophilic crosslinker, a hydrophobic crosslinker and optionally a hydrogel and methods of making and using the same
WO2020114714A1 (en) * 2018-12-05 2020-06-11 Evonik Operations Gmbh Process for preparing polymeric particles
KR20220128362A (ko) 2019-12-27 2022-09-20 에벨로 바이오사이언시즈, 인크. 박테리아 및 미생물 세포외 소포체를 함유하는 고체 투여 형태
WO2021146523A1 (en) 2020-01-17 2021-07-22 Evelo Biosciences, Inc. Solid dosage forms with improved disintegration profiles
EP4135670A1 (en) 2020-04-17 2023-02-22 Evelo Biosciences, Inc. Solid dosage forms with improved disintegration profiles
AU2021342481A1 (en) 2020-09-18 2023-05-04 Evelo Biosciences, Inc. Solid dosage forms of bacteria
WO2022061123A1 (en) 2020-09-21 2022-03-24 Evelo Biosciences, Inc. Solid dosage forms with improved disintegration profiles
KR20230127985A (ko) 2020-10-29 2023-09-01 에벨로 바이오사이언시즈, 인크. 스피룰리나 성분을 포함하는 조성물
EP4259806A1 (en) 2020-12-14 2023-10-18 Evelo Biosciences, Inc. Extracellular vesicle preparations
EP4267154A1 (en) 2020-12-22 2023-11-01 Evelo Biosciences, Inc. Compositions comprising animal hemoglobin
KR20230137968A (ko) 2021-01-26 2023-10-05 에벨로 바이오사이언시즈, 인크. 프레보텔라 세포외 소포체 제제
EP4297762A1 (en) 2021-02-26 2024-01-03 Evelo Biosciences, Inc. Compositions and methods for reducing cytokine expression
TW202302125A (zh) 2021-03-05 2023-01-16 美商艾弗洛生物科技股份有限公司 固體劑型
TW202304415A (zh) 2021-04-08 2023-02-01 美商艾弗洛生物科技股份有限公司 含有細菌的藥物製劑
WO2022221183A1 (en) 2021-04-12 2022-10-20 Evelo Biosciences, Inc. Fournierella extracellular vesicle preparations
WO2022251166A2 (en) 2021-05-25 2022-12-01 Evelo Biosciences, Inc. Bacterial compositions comprising soy hemoglobin
WO2023049268A1 (en) 2021-09-24 2023-03-30 Evelo Biosciences, Inc. Solid dosage forms containing bacteria and microbial extracellular vesicles
WO2023114293A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Extracellular vesicle assays
WO2023114300A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Fournierella massiliensis bacteria extracellular vesicle preparations
WO2023114295A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Veillonella parvula bacteria extracellular vesicle preparations
WO2023146843A1 (en) 2022-01-25 2023-08-03 Evelo Biosciences, Inc. Extracellular vesicle compositions and methods of use
WO2023183396A1 (en) 2022-03-22 2023-09-28 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
WO2023200837A1 (en) 2022-04-13 2023-10-19 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
WO2023239728A1 (en) 2022-06-07 2023-12-14 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles
WO2024102226A1 (en) 2022-10-14 2024-05-16 Evelo Biosciences, Inc. Methods for assaying drug substances and drug products by using cell lines with nf-kb- inducible reporter genes

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049179A1 (de) * 1975-03-20 1982-07-29 Röhm GmbH, 6100 Darmstadt Bindemittel fuer arzneimittelueberzuege.
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
GB1576075A (en) * 1976-04-12 1980-10-01 Union Carbide Australia Portable sprying device
HU202120B (en) * 1988-06-29 1991-02-28 Egyt Gyogyszervegyeszeti Gyar Process for film coating of medical compositions with polymer dispersions
JP2813809B2 (ja) * 1989-06-19 1998-10-22 武田薬品工業株式会社 有核顆粒製剤およびその製造法
US5292522A (en) * 1989-06-20 1994-03-08 Rohm Gmbh Aqueous film coating agent for solid medicaments
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
DK136595A (da) * 1995-12-01 1997-03-17 Aeromatic Fielder Ag An apparatus and a method for treating particulate materials
US6296876B1 (en) * 1997-10-06 2001-10-02 Isa Odidi Pharmaceutical formulations for acid labile substances
DE19809719A1 (de) * 1998-03-06 1999-09-09 Roehm Gmbh Wäßrige Dispersion geeignet zur Herstellung von Überzugs- und Bindemitteln für feste orale Arzneiformen
DE19918435A1 (de) * 1998-07-23 2000-01-27 Roehm Gmbh Überzugs- und Bindemittel für orale oder dermale Arzneiformen
ES2295062T3 (es) * 1999-09-02 2008-04-16 Nostrum Pharmaceuticals, Inc. Formulacion granulada de liberacion sostenida.
US6378789B1 (en) * 2000-06-01 2002-04-30 S. C. Johnson Commercial Markets, Inc. Combination spray apparatus
HU229344B1 (en) * 2001-02-27 2013-11-28 Evonik Roehm Gmbh Coating and binding agent for pharmaceutical formulations with improved storage stability
EP1240826A3 (de) * 2001-03-15 2003-11-05 Wissler, Erhard Sprühvorrichtung
DE10239999A1 (de) * 2002-08-27 2004-03-04 Röhm GmbH & Co. KG Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil

Also Published As

Publication number Publication date
AU2003280390A1 (en) 2004-07-22
WO2004058225A1 (de) 2004-07-15
CA2509913A1 (en) 2004-07-15
EP1572162A1 (de) 2005-09-14
DE10260919A1 (de) 2004-07-01
PL375917A1 (en) 2005-12-12
US20050271778A1 (en) 2005-12-08
MXPA05006285A (es) 2005-08-19
KR20050088189A (ko) 2005-09-02
JP2006515852A (ja) 2006-06-08

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Legal Events

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