BR0315597A - Processos de baixa dose para tratamento de distúrbios em que a atividade de tnf(alfa)é prejudicial - Google Patents

Processos de baixa dose para tratamento de distúrbios em que a atividade de tnf(alfa)é prejudicial

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Publication number
BR0315597A
BR0315597A BR0315597-8A BR0315597A BR0315597A BR 0315597 A BR0315597 A BR 0315597A BR 0315597 A BR0315597 A BR 0315597A BR 0315597 A BR0315597 A BR 0315597A
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BR
Brazil
Prior art keywords
tnf
low
harmful
activity
alpha
Prior art date
Application number
BR0315597-8A
Other languages
English (en)
Inventor
Zehra Kaymakcalan
Robert Kamen
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of BR0315597A publication Critical patent/BR0315597A/pt

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

"PROCESSOS DE BAIXA DOSE PARA TRATAMENTO DE DISTúRBIOS EM QUE A ATIVIDADE DE TNF<244> é PREJUDICIAL". Descreve-se um processo para tratamento de distúrbios de TNF<244>, em que o processo compreende a administração de uma quantidade de baixa dose de um inibidor de TNF<244>.
BR0315597-8A 2002-10-24 2003-10-24 Processos de baixa dose para tratamento de distúrbios em que a atividade de tnf(alfa)é prejudicial BR0315597A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42126202P 2002-10-24 2002-10-24
PCT/US2003/033973 WO2004037205A2 (en) 2002-10-24 2003-10-24 LOW DOSE METHODS FOR TREATING DISORDERS IN WHICH TNFα ACTIVITY IS DETRIMENTAL

Publications (1)

Publication Number Publication Date
BR0315597A true BR0315597A (pt) 2005-09-06

Family

ID=32176690

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315597-8A BR0315597A (pt) 2002-10-24 2003-10-24 Processos de baixa dose para tratamento de distúrbios em que a atividade de tnf(alfa)é prejudicial

Country Status (24)

Country Link
US (2) US8846046B2 (pt)
EP (3) EP2332565A1 (pt)
JP (3) JP5594803B2 (pt)
KR (4) KR20140117697A (pt)
CN (2) CN103623408A (pt)
AR (2) AR045710A1 (pt)
AT (1) ATE517632T1 (pt)
AU (2) AU2003301522B8 (pt)
BR (1) BR0315597A (pt)
CA (1) CA2497909A1 (pt)
DK (1) DK1578439T3 (pt)
ES (1) ES2370351T3 (pt)
MX (1) MXPA05004344A (pt)
MY (1) MY150740A (pt)
NZ (3) NZ596945A (pt)
PE (1) PE20040751A1 (pt)
PL (2) PL213215B1 (pt)
PT (1) PT1578439E (pt)
SA (1) SA04240497A (pt)
SI (1) SI1578439T1 (pt)
TW (3) TW201345552A (pt)
UY (1) UY28041A1 (pt)
WO (1) WO2004037205A2 (pt)
ZA (1) ZA200502983B (pt)

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US20140200332A1 (en) 2014-07-17
CN1732015A (zh) 2006-02-08
CN103623408A (zh) 2014-03-12
PT1578439E (pt) 2011-10-19
EP2295071A1 (en) 2011-03-16
PL398520A1 (pl) 2012-06-04
NZ539332A (en) 2009-10-30
EP1578439A4 (en) 2006-04-26
EP2332565A1 (en) 2011-06-15
KR20140117697A (ko) 2014-10-07
JP2012021001A (ja) 2012-02-02
NZ585493A (en) 2012-04-27
KR20120013443A (ko) 2012-02-14
NZ596945A (en) 2013-06-28
MXPA05004344A (es) 2005-08-02
TWI423817B (zh) 2014-01-21
JP2015028040A (ja) 2015-02-12
ES2370351T3 (es) 2011-12-14
PL376705A1 (pl) 2006-01-09
JP5676386B2 (ja) 2015-02-25
WO2004037205A3 (en) 2004-10-28
AU2003301522B2 (en) 2010-07-08
KR20050083805A (ko) 2005-08-26
US20040166111A1 (en) 2004-08-26
ATE517632T1 (de) 2011-08-15
TWI361696B (en) 2012-04-11
KR20110000757A (ko) 2011-01-05
TW201345552A (zh) 2013-11-16
SA04240497A (ar) 2005-12-03
AU2010206042A1 (en) 2010-08-19
TW201119679A (en) 2011-06-16
PL213215B1 (pl) 2013-01-31
UY28041A1 (es) 2004-05-31
AU2003301522A1 (en) 2004-05-13
TW200412999A (en) 2004-08-01
EP1578439A2 (en) 2005-09-28
DK1578439T3 (da) 2011-10-31
PE20040751A1 (es) 2004-11-18
WO2004037205A8 (en) 2005-04-14
ZA200502983B (en) 2006-09-27
SI1578439T1 (sl) 2011-12-30
EP1578439B1 (en) 2011-07-27
AR077573A2 (es) 2011-09-07
JP2006507286A (ja) 2006-03-02
CA2497909A1 (en) 2004-05-06
US8846046B2 (en) 2014-09-30
JP5594803B2 (ja) 2014-09-24
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AU2010206042B2 (en) 2012-12-13
WO2004037205A2 (en) 2004-05-06

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