BR0311687A - composições farmacêuticas estabilizadas com base em óleo de rìcino polioxietilado e método para a fabricação das mesmas - Google Patents

composições farmacêuticas estabilizadas com base em óleo de rìcino polioxietilado e método para a fabricação das mesmas

Info

Publication number
BR0311687A
BR0311687A BRPI0311687-5A BR0311687A BR0311687A BR 0311687 A BR0311687 A BR 0311687A BR 0311687 A BR0311687 A BR 0311687A BR 0311687 A BR0311687 A BR 0311687A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
manufacture
stabilized pharmaceutical
stabilized
compositions based
Prior art date
Application number
BRPI0311687-5A
Other languages
English (en)
Inventor
Vladimir Kysilka
Libuse Zatloukalova
Borek Zaludek
Karel Pospisilik
Marie Cigankova
Martin Kubat
Ales Cirkva
Original Assignee
Pliva Lachema As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema As filed Critical Pliva Lachema As
Publication of BR0311687A publication Critical patent/BR0311687A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS ESTABILIZADAS COM BASE EM óLEO DE RìCINO POLIOXIETILADO E MéTODO PARA A FABRICAçãO DAS MESMAS. A invenção se refere a uma composição farmacêutica estabilizada compreendendo uma substância farmaceuticamente ativa fracamente solúvel em água, um agente de solubilização com um baixo teor de compostos básicos e ácidos e um solvente orgânico polar, em particular um concentrado para injeção estabilizado, a métodos para o preparo de tais composições farmacêuticas estabilizadas e ao uso de um agente de solubilização com um baixo teor de compostos básicos e ácidos para estabilizar composições farmacêuticas com relação às substâncias farmaceuticamente ativas.
BRPI0311687-5A 2002-06-10 2003-05-16 composições farmacêuticas estabilizadas com base em óleo de rìcino polioxietilado e método para a fabricação das mesmas BR0311687A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20022027A CZ294371B6 (cs) 2002-06-10 2002-06-10 Stabilizovaná farmaceutická kompozice na bázi polyoxyethylovaného ricinového oleje a způsob její přípravy
PCT/EP2003/005153 WO2003103714A1 (en) 2002-06-10 2003-05-16 Stabilised pharmaceutical compositions on the basis of polyoxyethylated castor oil and method for manufacturing the same

Publications (1)

Publication Number Publication Date
BR0311687A true BR0311687A (pt) 2008-01-15

Family

ID=29721409

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0311687-5A BR0311687A (pt) 2002-06-10 2003-05-16 composições farmacêuticas estabilizadas com base em óleo de rìcino polioxietilado e método para a fabricação das mesmas

Country Status (19)

Country Link
US (1) US20050142225A1 (pt)
EP (1) EP1515751A1 (pt)
JP (1) JP2005534656A (pt)
KR (1) KR20050010030A (pt)
CN (1) CN1655824A (pt)
AU (1) AU2003240661A1 (pt)
BR (1) BR0311687A (pt)
CA (1) CA2487889A1 (pt)
CZ (1) CZ294371B6 (pt)
EA (1) EA007223B1 (pt)
HR (1) HRP20041107A2 (pt)
IL (2) IL165027A0 (pt)
IS (1) IS7551A (pt)
MX (1) MXPA04011990A (pt)
NZ (1) NZ537150A (pt)
PL (1) PL372071A1 (pt)
RS (1) RS106704A (pt)
WO (1) WO2003103714A1 (pt)
ZA (1) ZA200408892B (pt)

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JP2007532629A (ja) 2004-04-15 2007-11-15 キアスマ， インコーポレイテッド 生物学的障壁を横切る透過を促進し得る組成物
GT200500310A (es) * 2004-11-19 2006-06-19 Compuestos organicos
AU2006212177A1 (en) * 2005-02-10 2006-08-17 Sindan Pharma Srl Method of purifying a surfactant by ultrafiltration
EP1690551A3 (en) * 2005-02-10 2006-10-18 Sindan Pharma Srl Method of purifying a surfactant by ultrafiltration
SA06270147B1 (ar) 2005-06-09 2009-12-22 نوفارتيس ايه جي عملية لتخليق 5-(مثيل–1h–إيميدازول–1-يل )–3-(ثلاثي فلـورو مثيل)–بنزامـين
DE102007055341A1 (de) * 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
DE102008011691A1 (de) * 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilisierte, antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
CN101596159B (zh) * 2008-06-03 2012-12-19 哈药集团生物工程有限公司 一种紫杉醇注射液及其制备方法
JP5623406B2 (ja) 2008-09-17 2014-11-12 キアズマ インコーポレイテッド 医薬組成物および関連する送達方法
EP2358355B1 (en) * 2008-11-21 2013-11-06 Boehringer Ingelheim International GmbH Pharmaceutical composition of a potent hcv inhibitor for oral administration
PL2451438T3 (pl) 2009-07-07 2014-07-31 Boehringer Ingelheim Int Kompozycja farmaceutyczna inhibitora proteazy wirusowego zapalenia wątroby typu C
CN101829051B (zh) * 2010-05-31 2012-09-12 南昌弘益科技有限公司 1’-乙酰氧基胡椒酚乙酸酯注射液
WO2016126830A1 (en) 2015-02-03 2016-08-11 Chiasma Inc. Method of treating diseases
CN105497905A (zh) * 2015-12-30 2016-04-20 钟术光 一种供注射或口服用的辅料
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods
CN112778513A (zh) * 2020-12-30 2021-05-11 江苏优仿医药科技有限公司 一种聚氧乙烯蓖麻油的精制方法及其应用
CN113281425B (zh) * 2021-04-15 2023-06-06 四川汇宇制药股份有限公司 一种聚氧乙烯(35)蓖麻油中游离脂肪酸的检测方法

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JPS55108823A (en) * 1979-02-13 1980-08-21 Takemoto Oil & Fat Co Ltd Purification of alkylene oxide addition compound
US5112750A (en) * 1985-06-25 1992-05-12 Asama Chemical Co., Ltd. Immobilized cells and culture method utilizing the same
JPH02157274A (ja) * 1988-12-07 1990-06-18 Sumitomo Heavy Ind Ltd 植物油からビタミンｅを分離濃縮する方法
US6150398A (en) * 1991-05-08 2000-11-21 The United States Of America As Represented By The Department Of Health And Human Services Methods for the treatment of cancer
CA2086874E (en) * 1992-08-03 2000-01-04 Renzo Mauro Canetta Methods for administration of taxol
AU680441B2 (en) * 1992-09-22 1997-07-31 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Use of taxol for treating lymphomas and breast cancer
EP1500393A1 (en) * 1992-11-27 2005-01-26 Mayne Pharma (USA) Inc. Injectable composition containing taxol
KR100371062B1 (ko) * 1992-11-27 2003-04-21 에프.에이치.포울딩 앤드 컴퍼니 리미티드 안정성이향상된주사가능한택솔조성물및이를제형화하는방법
CA2092271C (en) * 1993-03-09 2009-10-13 Eddie Reed Use of g-csf for treating taxol side-effects
DE69434048T2 (de) * 1993-07-19 2005-10-06 Angiotech Pharmaceuticals, Inc., Vancouver Anti-angiogene Mittel und Verfahren zu deren Verwendung
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
DE69613273T2 (de) * 1995-04-28 2001-10-31 Loders Croklaan B.V., Wormerveer An polyungesättigten Fettsäuren reiche Triglyceride
DE19536165A1 (de) * 1995-09-28 1997-04-03 Basf Ag Verfahren zur Reinigung von alkoxylierten Fetten
US5925776A (en) * 1997-12-24 1999-07-20 Schein Pharmacetical, Inc. Polyethoxylated castor oil, process of making the same and formulations thereof
JP2000044840A (ja) * 1998-07-28 2000-02-15 Mitsubishi Heavy Ind Ltd 燃料ガス漏洩検知塗膜
DE19983660T1 (de) * 1998-10-20 2001-09-13 Ben Venue Lab Inc Verfahren zur Aufreinigung von Lösungsmitteln, die bei der Herstellung von pharmazeutischen Zusammensetzungen nützlich sind
JP4697569B2 (ja) * 1999-09-22 2011-06-08 日本アエロジル株式会社 表面改質シリカ微粉末とその用途
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US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability

Also Published As

Publication number Publication date
KR20050010030A (ko) 2005-01-26
IL165027A0 (en) 2005-12-18
ZA200408892B (en) 2006-01-25
EP1515751A1 (en) 2005-03-23
JP2005534656A (ja) 2005-11-17
RS106704A (en) 2006-12-15
US20050142225A1 (en) 2005-06-30
PL372071A1 (en) 2005-07-11
HRP20041107A2 (en) 2005-02-28
MXPA04011990A (es) 2005-08-16
EA200401625A1 (ru) 2005-06-30
WO2003103714A1 (en) 2003-12-18
CA2487889A1 (en) 2003-12-18
CZ294371B6 (cs) 2004-12-15
CZ20022027A3 (cs) 2004-01-14
EA007223B1 (ru) 2006-08-25
CN1655824A (zh) 2005-08-17
NZ537150A (en) 2006-09-29
IL165027A (en) 2009-12-24
IS7551A (is) 2004-11-25
AU2003240661A1 (en) 2003-12-22

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2157 DE 08/05/2012.