BR0311126A - Composições e método para tratar infecção em gado bovino e em suìnos - Google Patents

Composições e método para tratar infecção em gado bovino e em suìnos

Info

Publication number
BR0311126A
BR0311126A BR0311126-1A BR0311126A BR0311126A BR 0311126 A BR0311126 A BR 0311126A BR 0311126 A BR0311126 A BR 0311126A BR 0311126 A BR0311126 A BR 0311126A
Authority
BR
Brazil
Prior art keywords
cattle
pigs
compositions
treating infection
swine
Prior art date
Application number
BR0311126-1A
Other languages
English (en)
Other versions
BRPI0311126B1 (pt
Inventor
Raul E Kohan
Kanwal J Varma
Robert D Simmons
Abu Huq
Keith A Freehauf
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of BR0311126A publication Critical patent/BR0311126A/pt
Publication of BRPI0311126B1 publication Critical patent/BRPI0311126B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"COMPOSIçõES E MéTODO PARA TRATAR INFECçãO EM GADO BOVINO E EM SUìNOS". A presente invenção refere-se a formulações inusitadas que combinam uma droga antiinfiamatória não-esteróide (NSAID), tal como flunixina, com um antibiótico derivado de cloranfenicol ou tianfenicol fluorado, tal como florfenicol. Refere-se também métodos para usar tais formulações no tratamento e prevenção de doenças infecciosas de bovinos e suínos, inclusive doença respiratória bovina doença respiratória suína.
BRPI0311126A 2002-05-20 2003-05-19 composições para o tratamento de infecção em gado bovino e suínos e uso das mesmas na preparação de um medicamento BRPI0311126B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38201502P 2002-05-20 2002-05-20
PCT/IB2003/002152 WO2003097054A1 (en) 2002-05-20 2003-05-19 Compositions and method for treating infection in cattle and swine

Publications (2)

Publication Number Publication Date
BR0311126A true BR0311126A (pt) 2005-03-08
BRPI0311126B1 BRPI0311126B1 (pt) 2016-11-08

Family

ID=29550174

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0311126A BRPI0311126B1 (pt) 2002-05-20 2003-05-19 composições para o tratamento de infecção em gado bovino e suínos e uso das mesmas na preparação de um medicamento

Country Status (29)

Country Link
US (3) US6790867B2 (pt)
EP (1) EP1505975B1 (pt)
JP (2) JP4772324B2 (pt)
KR (1) KR101102176B1 (pt)
CN (1) CN100563655C (pt)
AR (1) AR039826A1 (pt)
AU (1) AU2003228042B2 (pt)
BR (1) BRPI0311126B1 (pt)
CA (1) CA2485491C (pt)
CY (1) CY1107176T1 (pt)
DE (1) DE60317662T2 (pt)
DK (1) DK1505975T3 (pt)
EC (1) ECSP045442A (pt)
ES (1) ES2295583T3 (pt)
HK (1) HK1072547A1 (pt)
IL (2) IL165252A0 (pt)
MX (1) MXPA04011516A (pt)
MY (1) MY135791A (pt)
NO (1) NO20045547L (pt)
NZ (1) NZ536476A (pt)
PE (1) PE20040041A1 (pt)
PL (1) PL213975B1 (pt)
PT (1) PT1505975E (pt)
RU (2) RU2330662C2 (pt)
SI (1) SI1505975T1 (pt)
TW (1) TWI355266B (pt)
UA (1) UA81629C2 (pt)
WO (1) WO2003097054A1 (pt)
ZA (1) ZA200409296B (pt)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11097058B2 (en) 2018-06-15 2021-08-24 James T. Doubet Syringe adapter for medication
US11090444B2 (en) 2018-06-15 2021-08-17 James T. Doubet Syringe adapter for medication
US10709850B2 (en) 2018-06-15 2020-07-14 James T. Doubet Syringe adapter for medication
US11337894B2 (en) 2018-06-15 2022-05-24 James T. Doubet Syringe adapter for animal medication
US6432203B1 (en) * 1997-03-17 2002-08-13 Applied Komatsu Technology, Inc. Heated and cooled vacuum chamber shield
US20070003508A1 (en) * 2005-07-01 2007-01-04 Wooley Richard E Methods and compositions for promoting wound healing
US20040208842A1 (en) * 2001-09-18 2004-10-21 Ritchie Branson W. Antimicrobial cleansing compositions and methods of use
US6787568B1 (en) * 2000-11-27 2004-09-07 Phoenix Scientific, Inc. Antibiotic/analgesic formulation and a method of making this formulation
AU2002335077B2 (en) * 2001-10-19 2006-09-07 Idexx Laboratories, Inc. Injectable compositions for the controlled delivery of pharmacologically active compound
US6790867B2 (en) * 2002-05-20 2004-09-14 Schering-Plough Animal Health Corporation Compositions and method for treating infection in cattle and swine
UA82359C2 (uk) * 2003-04-03 2008-04-10 Schering Plough Ltd Композиція (варіанти) і спосіб лікування мікробних і паразитних інфекцій у великої рогатої худоби і інших тварин
PE20050386A1 (es) * 2003-05-29 2005-06-23 Schering Plough Ltd Composiciones farmaceuticas de florfenicol
US7439268B2 (en) * 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
EP1677781A4 (en) * 2003-10-29 2008-11-19 Idexx Lab Inc SALTS OF PHARMACOLOGICALLY ACTIVE COMPOUNDS
KR100548948B1 (ko) * 2003-11-24 2006-02-02 주식회사 한동 플로르페니콜의 약제학적 조성물
US20070185202A1 (en) * 2004-03-03 2007-08-09 University Of Georgia Research Foundation, Inc. Methods and compositions for ophthalmic treatment of fungal and bacterial infections
EP1836162A2 (en) * 2004-09-02 2007-09-26 IDEXX Laboratories Inc Antibacterial agents
CA2591307C (en) * 2004-12-21 2012-12-04 Intervet International B.V. Injectable veterinary composition
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
WO2008076259A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
WO2008076256A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
KR20090090387A (ko) * 2006-12-19 2009-08-25 쉐링-프라우 리미티드 음료수 시스템 내에 추가하기 위한 플로르페니콜의 비등성 제형
PE20081406A1 (es) * 2006-12-20 2008-10-17 Schering Plough Ltd Composiciones farmaceuticas de flunixina
RU2009143731A (ru) * 2007-04-27 2011-06-10 Шеринг-Плоу Лтд. (CH) Соединения и способы улучшения растворимости флорфеникола и структурно родственных антибиотиков с помощью циклодекстринов
US7550625B2 (en) 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
US20090170954A1 (en) * 2007-12-14 2009-07-02 Schering-Plough Ltd. Process for Recovering Florfenicol and Florfenicol Analogs
ES2384903T3 (es) * 2007-12-14 2012-07-13 Intervet International B.V. Proceso para recuperar flunixina a partir de composiciones farmacéuticas
FR2925334A1 (fr) * 2007-12-21 2009-06-26 Ceva Sante Animale Sa Nouvelles compositions antibacteriennes
WO2009143558A1 (en) * 2008-05-26 2009-12-03 Silphion Pty Limited Injectable formulations
CN101461821B (zh) * 2008-07-04 2011-05-18 青岛康地恩药业有限公司 一种用于治疗猪、牛呼吸道疾病的复方口服药物组合物
UA103774C2 (uk) 2008-07-23 2013-11-25 Амбркс, Інк. Модифіковані поліпептиди бичачого гранулоцитарного колонієстимулювального фактора (g-csf) та їх застосування
JP2011529895A (ja) * 2008-07-30 2011-12-15 インターベツト・インターナシヨナル・ベー・ベー フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
BRPI1002021A2 (pt) * 2010-01-21 2012-05-22 Nanocore Biotecnologia S A composições farmacêuticas para tratamento de infecções bacterianas
AR083006A1 (es) 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
CN102188422B (zh) * 2011-01-11 2013-11-06 广东大华农动物保健品股份有限公司 一种复方氟苯尼考注射液及其制备方法和应用
EA019956B1 (ru) * 2011-02-24 2014-07-30 Закрытое Акционерное Общество "Нита-Фарм" Фармацевтическая композиция для лечения заболеваний бактериальной и микоплазменной этиологии
UA110436C2 (en) * 2012-03-06 2015-12-25 Zoetis Llc Antibacterial phenol compounds
AU2013324198C1 (en) * 2012-09-26 2017-08-10 Zoetis Services Llc Phenicol antibacterial agents
CN102920701A (zh) * 2012-11-02 2013-02-13 青岛康地恩药业股份有限公司 一种用于治疗猪呼吸道感染疾病的复方氟苯尼考制剂及其制备方法
CN104208062A (zh) * 2013-06-03 2014-12-17 中国农业科学院兰州畜牧与兽药研究所 一种高浓度复方氟苯尼考注射液及其制备方法和应用
CN104188901A (zh) * 2014-08-12 2014-12-10 河南迪冉生物科技有限公司 一种兽用氟苯尼考注射液及其制备方法
CN104095996A (zh) * 2014-08-12 2014-10-15 王忠亮 一种治疗急性脓肿期乳腺炎的药物组合物
CN104370782A (zh) * 2014-11-29 2015-02-25 郑州后羿制药有限公司 一种氟苯尼考的精制方法
RU2655772C1 (ru) * 2016-12-26 2018-05-29 Федеральное государственное бюджетное научное учреждение "Курский научно-исследовательский институт агропромышленного производства" Йодсодержащий состав для лечения мастита у коров
USD890925S1 (en) 2018-06-15 2020-07-21 James T. Doubet Syringe adapter for medication
US20190388625A1 (en) 2018-06-15 2019-12-26 James T. Doubet Syringe adapter for medication
CN108904442B (zh) * 2018-08-09 2021-04-06 山西瑞象生物药业有限公司 一种氟苯尼考溶液剂及其制备方法
JP7532341B2 (ja) * 2018-09-06 2024-08-13 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド 注射可能な徐放性の抗生物質製剤
CN110208397B (zh) * 2019-05-17 2022-08-19 河北远征药业有限公司 一种同时测定土霉素氟尼辛注射液中两种主药含量的高效液相色谱法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3025325A1 (de) * 1980-07-04 1982-02-04 Merck Patent Gmbh, 6100 Darmstadt Neue 13-thiaprostaglandin-zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von 13-thiaprostaglandin-derivaten
US5082863A (en) * 1990-08-29 1992-01-21 Schering Corporation Pharmaceutical composition of florfenicol
US5082653A (en) * 1990-10-31 1992-01-21 Warner-Lambert Company Anti-plaque compositions comprising a combination of morpholinoamino alcohol and antibiotic
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
SK124099A3 (en) 1997-05-06 2000-12-11 Norbrook Lab Ltd A method for producing a veterinary product
JP2003512290A (ja) * 1997-09-10 2003-04-02 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての8a−アザライド
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
JP2002544210A (ja) * 1999-05-14 2002-12-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 炎症で仲介される感染症に対する抗炎症性治療方法
US6787568B1 (en) 2000-11-27 2004-09-07 Phoenix Scientific, Inc. Antibiotic/analgesic formulation and a method of making this formulation
US6790867B2 (en) * 2002-05-20 2004-09-14 Schering-Plough Animal Health Corporation Compositions and method for treating infection in cattle and swine
PE20050386A1 (es) * 2003-05-29 2005-06-23 Schering Plough Ltd Composiciones farmaceuticas de florfenicol

Also Published As

Publication number Publication date
US6790867B2 (en) 2004-09-14
EP1505975B1 (en) 2007-11-21
RU2008107582A (ru) 2009-09-10
ZA200409296B (en) 2005-07-27
NO20045547L (no) 2004-12-17
DE60317662T2 (de) 2008-10-30
MY135791A (en) 2008-06-30
HK1072547A1 (en) 2005-09-02
CN1652783A (zh) 2005-08-10
US8044102B2 (en) 2011-10-25
SI1505975T1 (sl) 2008-06-30
CY1107176T1 (el) 2012-10-24
KR101102176B1 (ko) 2012-01-02
BRPI0311126B1 (pt) 2016-11-08
US20030216447A1 (en) 2003-11-20
WO2003097054A1 (en) 2003-11-27
PL374575A1 (en) 2005-10-31
RU2466726C2 (ru) 2012-11-20
KR20050010818A (ko) 2005-01-28
ES2295583T3 (es) 2008-04-16
MXPA04011516A (es) 2005-02-14
RU2330662C2 (ru) 2008-08-10
DE60317662D1 (de) 2008-01-03
US20030220302A1 (en) 2003-11-27
JP2005526849A (ja) 2005-09-08
JP4772324B2 (ja) 2011-09-14
PL213975B1 (pl) 2013-05-31
AU2003228042B2 (en) 2006-09-21
RU2004137273A (ru) 2005-07-10
JP2006213731A (ja) 2006-08-17
CN100563655C (zh) 2009-12-02
AU2003228042A1 (en) 2003-12-02
TW200307536A (en) 2003-12-16
EP1505975A1 (en) 2005-02-16
AR039826A1 (es) 2005-03-02
IL165252A0 (en) 2005-12-18
ECSP045442A (es) 2005-01-03
PT1505975E (pt) 2008-01-31
TWI355266B (en) 2012-01-01
CA2485491A1 (en) 2003-11-27
PE20040041A1 (es) 2004-01-24
DK1505975T3 (da) 2008-01-14
UA81629C2 (ru) 2008-01-25
US20050288261A1 (en) 2005-12-29
IL165252A (en) 2011-11-30
NZ536476A (en) 2008-10-31
CA2485491C (en) 2012-12-04

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