BR0308929A - Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila - Google Patents

Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila

Info

Publication number
BR0308929A
BR0308929A BR0308929-0A BR0308929A BR0308929A BR 0308929 A BR0308929 A BR 0308929A BR 0308929 A BR0308929 A BR 0308929A BR 0308929 A BR0308929 A BR 0308929A
Authority
BR
Brazil
Prior art keywords
formula
dichloro
alkyl
nitrile
moles
Prior art date
Application number
BR0308929-0A
Other languages
English (en)
Inventor
Silvia Krich
Bernhard Holub
Original Assignee
Dsm Fine Chem Austria Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Fine Chem Austria Gmbh filed Critical Dsm Fine Chem Austria Gmbh
Publication of BR0308929A publication Critical patent/BR0308929A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/18—Preparation of carboxylic acid esters by conversion of a group containing nitrogen into an ester group
    • C07C67/22—Preparation of carboxylic acid esters by conversion of a group containing nitrogen into an ester group from nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

"PROCESSO PARA PREPARAR 2,2-DICLORO- OU DIBROMOFENILACETATOS DE ALQUILA". A invenção refere-se a um método melhorado para produzir acetatos de 2,2-dicloro- ou dibromo-fenil alquila da fórmula (1), em que X representa Cl ou Br, n representa um número inteiro de 1 a 5, R representa hidrogênio, C~ 1~-C~ 8~-alquila, arila, heteroadila, C~ 1~-C~ 8~-alcóxi, arilóxi ou halogênio, e R1 representa C~ 1~-C~ 8~-alquila. De acordo com o referido método, um 2,2-dicloro- ou dibromofenilacetonitrila da fórmula (II) é reagido em 0,8 a 2 moles de água por mol de nitrila da fórmula (II), de 1 a 8 moles de álcool de fórmula R1OH (III) por moL de nitrila da fórmula (II) e na presença de 1 a 3 moles de HCI ou HBr por mol de nitrila da fórmula (II), opcionalmente na presença de um solvente que é inerte nas condições de reação, para formar os acetatos de 2,2-dicloro- ou dibromofenil alquila correspondentes da fórmula (I), desse modo a temperatura de reação na primeira fase fica entre 30 e 60<198>C e, na segunda fase, entre 60 e 100<198>C. Uma vez que a reação tem ocorrido, a mistura de reação é resfriada a entre 20 e 40<198>C, diluída com água, e o acetato de 2,2-dicloro- ou dibromofenil alquila da fórmula (I) é isolado.
BR0308929-0A 2002-04-04 2003-03-10 Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila BR0308929A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0052302A AT500469B1 (de) 2002-04-04 2002-04-04 Verbessertes verfahren zur herstellung von 2,2-dichlorophenylessigsäurealkylestern
PCT/EP2003/002407 WO2003084918A1 (de) 2002-04-04 2003-03-10 Verfahren zur herstellung von 2,2-dichloro-oder dibromo-phenylessigsäurealkylestern

Publications (1)

Publication Number Publication Date
BR0308929A true BR0308929A (pt) 2005-01-04

Family

ID=28679361

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0308929-0A BRPI0308929B1 (pt) 2002-04-04 2003-03-10 Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila
BR0308929-0A BR0308929A (pt) 2002-04-04 2003-03-10 Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0308929-0A BRPI0308929B1 (pt) 2002-04-04 2003-03-10 Processo para preparar 2,2-dicloro- ou dibromofenilacetatos de alquila

Country Status (13)

Country Link
US (1) US20050131246A1 (pt)
EP (1) EP1490322B1 (pt)
JP (1) JP4686129B2 (pt)
CN (1) CN100516015C (pt)
AT (1) AT500469B1 (pt)
AU (1) AU2003212321B2 (pt)
BR (2) BRPI0308929B1 (pt)
CA (1) CA2479643C (pt)
ES (1) ES2549401T3 (pt)
IL (1) IL163964A (pt)
PL (1) PL215180B1 (pt)
RU (1) RU2320639C2 (pt)
WO (1) WO2003084918A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911057B (zh) * 2011-08-04 2016-01-27 浙江九洲药业股份有限公司 一种酮洛芬乙酯的制备方法
CN109020834A (zh) * 2018-08-30 2018-12-18 南平铭正医药化学有限公司 一种2,2-二氯苯乙腈的制备方法
CN109485566B (zh) * 2018-11-23 2019-10-11 宁波江润化工有限公司 一种氧代苯乙酸酯的新合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2827977A1 (de) * 1978-06-26 1980-01-17 Bayer Ag Verfahren zur herstellung von mandelsaeureestern
NL8104287A (nl) * 1981-09-17 1983-04-18 Stamicarbon De bereiding van derivaten van dichloorazijnzure esters.
NL8104286A (nl) * 1981-09-17 1983-04-18 Stamicarbon Werkwijze voor de bereiding van 2,2-dichloorfenylazijnzure esters.
NL9100979A (nl) * 1991-06-07 1993-01-04 Dsm Nv Werkwijze voor de alpha-chlorering van fenylacetonitrillen.

Also Published As

Publication number Publication date
PL215180B1 (pl) 2013-10-31
US20050131246A1 (en) 2005-06-16
JP4686129B2 (ja) 2011-05-18
CA2479643A1 (en) 2003-10-16
EP1490322A1 (de) 2004-12-29
RU2320639C2 (ru) 2008-03-27
PL374094A1 (en) 2005-09-19
ES2549401T3 (es) 2015-10-27
CA2479643C (en) 2011-01-25
CN1642898A (zh) 2005-07-20
AT500469A1 (de) 2006-01-15
IL163964A0 (en) 2005-12-18
IL163964A (en) 2011-02-28
RU2004132213A (ru) 2005-04-20
AU2003212321A1 (en) 2003-10-20
JP2006508024A (ja) 2006-03-09
AU2003212321B2 (en) 2009-05-28
CN100516015C (zh) 2009-07-22
WO2003084918A1 (de) 2003-10-16
BRPI0308929B1 (pt) 2019-04-24
EP1490322B1 (de) 2015-07-29
AT500469B1 (de) 2007-04-15

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 13 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ESIM CHEMICALS GMBH (AT)

B25A Requested transfer of rights approved

Owner name: ESIM CHEMICALS GMBH (AT)

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/04/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/04/2019, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 19A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2661 DE 04-01-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.