BR0213843A - Derivado de quinazolina, processo para a preparação de um derivado de quinazolina, composição farmacêutica, e, uso de um derivado de quinazolina - Google Patents

Derivado de quinazolina, processo para a preparação de um derivado de quinazolina, composição farmacêutica, e, uso de um derivado de quinazolina

Info

Publication number
BR0213843A
BR0213843A BR0213843-3A BR0213843A BR0213843A BR 0213843 A BR0213843 A BR 0213843A BR 0213843 A BR0213843 A BR 0213843A BR 0213843 A BR0213843 A BR 0213843A
Authority
BR
Brazil
Prior art keywords
quinazoline derivative
pharmaceutical composition
quinazoline
preparing
derivative
Prior art date
Application number
BR0213843-3A
Other languages
English (en)
Inventor
Laurent Francois And Hennequin
Jason Grant Kettle
Martin Pass
Robert Hugh Bradbury
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0213843A publication Critical patent/BR0213843A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

"DERIVADO DE QUINAZOLINA, PROCESSO PARA A PREPARAçãO DE UM DERIVADO DE QUINAZOLINA, COMPOSIçãO FARMACêUTICA, E, USO DE UM DERIVADO DE QUINAZOLINA". A invenção refere-se a derivados de quinazolina da fórmula (I); em que cada um de Q^ 1^, Q^ 2^, Z, R^ 1^, R^ 2^, R^ 3^, L e m possuem qualquer dos significados definidos na descrição; processos para a sua preparação, composições farmacêuticas contendo os mesmos e sua uso na manufatura de um medicamento para o uso na prevenção ou tratamento de tumores que são sensíveis à inibição de tirosina quinase do receptor erbB.
BR0213843-3A 2001-11-03 2002-10-31 Derivado de quinazolina, processo para a preparação de um derivado de quinazolina, composição farmacêutica, e, uso de um derivado de quinazolina BR0213843A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0126433.2A GB0126433D0 (en) 2001-11-03 2001-11-03 Compounds
PCT/GB2002/004932 WO2003040109A2 (en) 2001-11-03 2002-10-31 Quinazoline derivatives as antitumor agents

Publications (1)

Publication Number Publication Date
BR0213843A true BR0213843A (pt) 2004-08-31

Family

ID=9925096

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0213843-3A BR0213843A (pt) 2001-11-03 2002-10-31 Derivado de quinazolina, processo para a preparação de um derivado de quinazolina, composição farmacêutica, e, uso de um derivado de quinazolina

Country Status (25)

Country Link
US (2) US20050054662A1 (pt)
EP (1) EP1444211B1 (pt)
JP (1) JP2005511603A (pt)
KR (1) KR20050042058A (pt)
CN (1) CN1764651A (pt)
AR (1) AR037193A1 (pt)
AT (1) ATE421507T1 (pt)
BR (1) BR0213843A (pt)
CA (1) CA2465100A1 (pt)
CO (1) CO5580775A2 (pt)
DE (1) DE60230995D1 (pt)
ES (1) ES2319880T3 (pt)
GB (1) GB0126433D0 (pt)
HK (1) HK1065801A1 (pt)
HU (1) HUP0401994A2 (pt)
IL (1) IL161620A0 (pt)
IS (1) IS7241A (pt)
MX (1) MXPA04004220A (pt)
NO (1) NO20042288L (pt)
NZ (1) NZ532523A (pt)
PL (1) PL369833A1 (pt)
RU (1) RU2004116908A (pt)
TW (1) TW200302221A (pt)
WO (1) WO2003040109A2 (pt)
ZA (2) ZA200403203B (pt)

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JP2005511603A (ja) 2005-04-28
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ZA200403203B (en) 2005-07-28
ZA200403200B (en) 2005-07-28
WO2003040109A3 (en) 2003-06-26
PL369833A1 (en) 2005-05-02
MXPA04004220A (es) 2004-09-10
GB0126433D0 (en) 2002-01-02
KR20050042058A (ko) 2005-05-04
US20050054662A1 (en) 2005-03-10
HK1065801A1 (en) 2005-03-04
CO5580775A2 (es) 2005-11-30
CN1764651A (zh) 2006-04-26
ES2319880T3 (es) 2009-05-14
IS7241A (is) 2004-04-30
EP1444211B1 (en) 2009-01-21
NO20042288L (no) 2004-06-03
TW200302221A (en) 2003-08-01
US20070088044A1 (en) 2007-04-19
DE60230995D1 (de) 2009-03-12
WO2003040109A2 (en) 2003-05-15
RU2004116908A (ru) 2005-11-10
CA2465100A1 (en) 2003-05-15
AR037193A1 (es) 2004-10-27
HUP0401994A2 (hu) 2005-01-28
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IL161620A0 (en) 2004-09-27

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