BR0209138A - Utilização de derivados de piridoindolona para a preparação de medicamentos - Google Patents

Utilização de derivados de piridoindolona para a preparação de medicamentos

Info

Publication number
BR0209138A
BR0209138A BR0209138-0A BR0209138A BR0209138A BR 0209138 A BR0209138 A BR 0209138A BR 0209138 A BR0209138 A BR 0209138A BR 0209138 A BR0209138 A BR 0209138A
Authority
BR
Brazil
Prior art keywords
drug preparation
derivatives
preparation
pyridoindolone derivatives
pyridoindolone
Prior art date
Application number
BR0209138-0A
Other languages
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Jean-Marie Derocq
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of BR0209138A publication Critical patent/BR0209138A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"UTILIZAçãO DE DERIVADOS DE PIRIDOINDOLONA PARA A PREPARAçãO DE MEDICAMENTOS". A presente invenção refere-se a uma nova utilização dos compostos de fórmula (I) para a preparação de medicamentos úteis como anticancerígenos.
BR0209138-0A 2001-04-27 2002-04-26 Utilização de derivados de piridoindolona para a preparação de medicamentos BR0209138A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105843A FR2823975B1 (fr) 2001-04-27 2001-04-27 Nouvelle utilisation de pyridoindolone
PCT/FR2002/001449 WO2002087574A2 (fr) 2001-04-27 2002-04-26 Utilisation de derives de pyridoindolone pour la preparation de medicaments anticancereux

Publications (1)

Publication Number Publication Date
BR0209138A true BR0209138A (pt) 2004-06-08

Family

ID=8862882

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209138-0A BR0209138A (pt) 2001-04-27 2002-04-26 Utilização de derivados de piridoindolona para a preparação de medicamentos

Country Status (34)

Country Link
US (3) US7524857B2 (pt)
EP (2) EP1385512B1 (pt)
JP (2) JP2004528343A (pt)
KR (1) KR100847413B1 (pt)
CN (2) CN1505511A (pt)
AR (1) AR034313A1 (pt)
AT (2) ATE314070T1 (pt)
BG (2) BG108260A (pt)
BR (1) BR0209138A (pt)
CA (2) CA2443012C (pt)
CY (1) CY1105813T1 (pt)
CZ (2) CZ299465B6 (pt)
DE (2) DE60214533T2 (pt)
DK (2) DK1385512T3 (pt)
EA (1) EA005930B1 (pt)
EE (2) EE200300465A (pt)
ES (2) ES2254683T3 (pt)
FR (1) FR2823975B1 (pt)
HK (2) HK1059895A1 (pt)
HU (2) HUP0400744A2 (pt)
IL (4) IL158312A0 (pt)
IS (1) IS2441B (pt)
MX (1) MXPA03009639A (pt)
NO (2) NO20034787L (pt)
NZ (1) NZ528671A (pt)
PL (2) PL366910A1 (pt)
PT (2) PT1385513E (pt)
RS (2) RS50791B (pt)
RU (1) RU2292888C9 (pt)
SK (2) SK13252003A3 (pt)
TW (1) TWI252104B (pt)
UA (1) UA74876C2 (pt)
WO (2) WO2002087575A1 (pt)
ZA (1) ZA200307785B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) * 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
FR2846329B1 (fr) * 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) * 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) * 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) * 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
SU833972A1 (ru) 1979-10-26 1981-05-30 Институт Физико-Органической Химиии Углехимии Ah Украинской Ccp Имидазо(4,5-с)пиридиний иодиды вКАчЕСТВЕ пРОМЕжуТОчНыХ пРОдуКТОВ дл СиНТЕзА фуНгицидОВ
FR2595701B1 (fr) * 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
US5035252A (en) * 1990-12-14 1991-07-30 Mondre Steven J Nicotine-containing dental floss
JPH10501686A (ja) * 1994-04-13 1998-02-17 ザ ロックフェラー ユニヴァーシティ 神経系の細胞へのｄｎａのａａｖ仲介送達
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
FR2765581B1 (fr) * 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
CA2326319A1 (en) * 1998-04-02 1999-10-14 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino[2,3-b]indole and 5,6,7,8-tetrahydro-9h-pyrimidino[4,5-b]indole derivatives: crf1 specific ligands
IT1313592B1 (it) 1999-08-03 2002-09-09 Novuspharma Spa Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) * 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) * 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
FR2846329B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2846330B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
US6958347B2 (en) 2002-12-18 2005-10-25 Pfizer Inc. Aminophenanthridinone and aminophenanthridine as NPY-5 antagonists
FR2869316B1 (fr) 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
US20040122027A1 (en) 2004-06-24
NO20034787L (no) 2003-12-23
RS50791B (sr) 2010-08-31
PL366916A1 (en) 2005-02-07
JP2004531538A (ja) 2004-10-14
CN1505510A (zh) 2004-06-16
MXPA03009639A (es) 2004-06-30
NO20034785L (no) 2003-12-23
RU2292888C9 (ru) 2007-06-20
US7524857B2 (en) 2009-04-28
ZA200307785B (en) 2004-10-06
CY1105813T1 (el) 2011-02-02
EP1385512B1 (fr) 2005-12-28
DK1385512T3 (da) 2006-05-22
PT1385512E (pt) 2006-05-31
CA2443012A1 (en) 2002-11-07
CZ295224B6 (cs) 2005-06-15
CZ20032909A3 (en) 2004-06-16
SK13252003A3 (sk) 2004-03-02
IL158312A (en) 2009-09-01
DE60214533T2 (de) 2007-06-21
US20050272760A1 (en) 2005-12-08
CN1240382C (zh) 2006-02-08
EP1385512A2 (fr) 2004-02-04
FR2823975B1 (fr) 2003-05-30
DE60208365D1 (de) 2006-02-02
HK1060066A1 (en) 2004-07-30
RU2003130376A (ru) 2005-04-10
EA200301062A1 (ru) 2004-04-29
US7160895B2 (en) 2007-01-09
IL158266A0 (en) 2004-05-12
UA74876C2 (en) 2006-02-15
EE200300466A (et) 2003-12-15
YU83903A (sh) 2006-08-17
WO2002087575A1 (fr) 2002-11-07
CN1505511A (zh) 2004-06-16
EP1385513A1 (fr) 2004-02-04
CZ299465B6 (cs) 2008-08-06
NZ528671A (en) 2004-06-25
NO20034785D0 (no) 2003-10-24
YU83403A (sh) 2006-08-17
IL158266A (en) 2009-09-01
DK1385513T3 (da) 2007-01-15
JP2004528343A (ja) 2004-09-16
BG108260A (bg) 2004-12-30
EP1385513B1 (fr) 2006-09-06
HUP0400745A2 (hu) 2004-08-30
ES2254683T3 (es) 2006-06-16
RU2292888C2 (ru) 2007-02-10
ES2271264T3 (es) 2007-04-16
PT1385513E (pt) 2007-01-31
WO2002087574A3 (fr) 2003-02-13
KR100847413B1 (ko) 2008-07-18
EE200300465A (et) 2003-12-15
TWI252104B (en) 2006-04-01
WO2002087574A2 (fr) 2002-11-07
US20040122036A1 (en) 2004-06-24
RS50790B (sr) 2010-08-31
ATE314070T1 (de) 2006-01-15
HK1059895A1 (en) 2004-07-23
PL366910A1 (en) 2005-02-07
ATE338548T1 (de) 2006-09-15
BG108261A (bg) 2004-12-30
CA2444334A1 (fr) 2002-11-07
HUP0400744A2 (hu) 2004-06-28
US6967203B2 (en) 2005-11-22
DE60214533D1 (de) 2006-10-19
NO20034787D0 (no) 2003-10-24
CA2443012C (fr) 2009-07-28
KR20040015138A (ko) 2004-02-18
DE60208365T2 (de) 2006-09-07
IS2441B (is) 2008-11-15
IL158312A0 (en) 2004-05-12
AR034313A1 (es) 2004-02-18
CZ20032910A3 (en) 2004-07-14
EA005930B1 (ru) 2005-08-25
SK13242003A3 (sk) 2004-03-02
FR2823975A1 (fr) 2002-10-31
IS6984A (is) 2003-10-09

Similar Documents

Publication Publication Date Title
BR0112589A (pt) Derivados de heteroarila e sua aplicação como medicamento
BR0112591A (pt) Derivados de acridina e sua aplicação como medicamento
BR0312513A (pt) Derivados de glicosìdeo de tiofeno, processos para a produção dos mesmos, medicamentos que contêm esses compostos e uso dos mesmos
CU23105A3 (es) DERIVADOS NOVEDOSOS DEL áCIDO AMINODICARBOXILICO CON PROPIEDADES FARMACéUTICAS
BR0116607A (pt) Derivados de glicopiranosiloxipirazol e uso dos mesmos em medicamentos
AR025444A1 (es) Derivados de sulfonil-carboxamida, procedimientos para su preparacion y su utilizacion como medicamentos
BR0014827A (pt) Derivados de terc-butil-(7-metil-imidazo (1,2-a) piridin-3-il) amina, procedimento de sua preparação, medicamentos que os contém, sua utilização para a preparação de medicamento para inibição de no-sintase e composições farmacêuticas que os contém
AR029175A1 (es) Derivados 2-amino-fenilpurina, un proceso para su preparacion, composicion farmaceutica que los comprende, y el uso de los mismos para la preparacion de un medicamento
BR0108395A (pt) Derivados de pirrolopirimidinona, processos de preparação e uso
AU2002218167A1 (en) N-phenyl-2-pyrimidine-amine derivatives
BR0013667A (pt) Derivados de glucopiranosiloxipirazol, composições medicinais contendo os mesmos derivados e seus intermediários na produção dos mesmos
BR0314302A (pt) Compostos de pirazol como inibidores do fator de crescimento trnasformante (tgf)
BR0014178A (pt) Derivados de ácido dicarboxìlico com propriedades farmacêuticas
CY1113269T1 (el) Παραγωγα ινδαζολυλ αμιδιου για τη θεραπευτικη αγωγη διαταραχων διαμεσολαβουμενων υπο υποδοχεα γλυκοκορτικοειδων
BRPI0610850A2 (pt) derivados de Ácido aril alquila, composiÇço farmacÊutica, medicamento, bem como uso dos referidos derivados
BR0314577A (pt) Derivados de triazol como inibidores do fator de crescimento de transformação (tgf)
BR0309083A (pt) Compostos derivados de benzoxazinona, sua preparação e uso como medicamentos
EE200200207A (et) Kinoliiniderivaatide kasutamine vähivastase ravimi valmistamiseks, ühendite saamine ning neid sisaldavad farmatseutilised kompositsioonid
MY124146A (en) Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same
MY123193A (en) Novel 2-(iminomethyl)amino-phenyl derivatives,preparation,application as medicines and compositions containing same
BR0211601A (pt) Polimorfo estável de flibanserina, processo técnico para a preparação do mesmo e o uso do mesmo para a preparação de medicamentos
SE9901573D0 (sv) New compounds
AR012504A1 (es) Utilizacion de derivados de tetrahidropiridina, para la preparacion de medicamentos para el tratamiento de las enfermedades que provocan unadesmielinizacion.
BR0112807A (pt) Derivados de indol e sua aplicação como medicamento
EA200501870A1 (ru) Новые производные имидазолов, способ их получения и их применение в качестве лекарственного средства

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS (FR)

Free format text: ALTERADO DE: SANOFI-SYNTHELABO

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 9A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.