BR0116229A - Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas - Google Patents

Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas

Info

Publication number
BR0116229A
BR0116229A BR0116229-2A BR0116229A BR0116229A BR 0116229 A BR0116229 A BR 0116229A BR 0116229 A BR0116229 A BR 0116229A BR 0116229 A BR0116229 A BR 0116229A
Authority
BR
Brazil
Prior art keywords
quinolones
manufacture
process step
naphthyridines
cyclization process
Prior art date
Application number
BR0116229-2A
Other languages
English (en)
Inventor
Sreenivasa Reddy Mundla
Jared Lynn Randall
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR0116229A publication Critical patent/BR0116229A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"ETAPA DE PROCESSO DE CICLIZAçãO NA FABRICAçãO DE QUINOLONAS E NAFTIRIDINAS". A presente invenção refere-se a um processo de fabricação de um composto que tem uma estrutura de acordo com a Fórmula (I): sendo que o processo compreende a reação de um ou mais reagentes de organossilícios com um composto que tem a estrutura da fórmula (A).
BR0116229-2A 2000-12-14 2001-12-07 Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas BR0116229A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25563300P 2000-12-14 2000-12-14
PCT/US2001/048536 WO2002048113A1 (en) 2000-12-14 2001-12-07 Cyclization process step in the making of quinolones and naphthyridines

Publications (1)

Publication Number Publication Date
BR0116229A true BR0116229A (pt) 2003-11-04

Family

ID=22969207

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116229-2A BR0116229A (pt) 2000-12-14 2001-12-07 Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas

Country Status (19)

Country Link
EP (1) EP1343766B1 (pt)
JP (2) JP4417007B2 (pt)
KR (1) KR100603163B1 (pt)
CN (1) CN1232508C (pt)
AT (1) ATE300522T1 (pt)
AU (2) AU2905702A (pt)
BR (1) BR0116229A (pt)
CA (1) CA2427831C (pt)
CZ (1) CZ20031379A3 (pt)
DE (1) DE60112325T2 (pt)
DK (1) DK1343766T3 (pt)
ES (1) ES2247190T3 (pt)
HU (1) HUP0303991A3 (pt)
IL (2) IL155677A0 (pt)
MX (1) MXPA03005338A (pt)
NO (1) NO325236B1 (pt)
NZ (1) NZ525569A (pt)
PL (1) PL207394B1 (pt)
WO (1) WO2002048113A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100735587B1 (ko) * 2002-08-05 2007-07-04 더 프록터 앤드 갬블 캄파니 퀴놀론계 항생제 중간체의 제조 방법
US6803469B2 (en) * 2002-08-05 2004-10-12 The Procter & Gamble Company Process for preparing quinolone antibiotic intermediates
EP1564210B9 (en) * 2002-11-20 2010-03-31 Japan Tobacco Inc. 4-oxoquinoline compounds and utilization thereof as hiv integrase inhibitors
US7402674B2 (en) 2004-01-31 2008-07-22 Sanofi-Aventis Deutschland Gmbh, 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
US8420821B2 (en) 2006-03-06 2013-04-16 Japan Tobacco Inc. Process for production of 4-oxoquinoline compound
KR101023635B1 (ko) 2006-03-06 2011-03-22 니뽄 다바코 산교 가부시키가이샤 4-옥소퀴놀린 화합물 제조 방법
AR063710A1 (es) 2006-09-12 2009-02-11 Gilead Sciences Inc Proceso para la preparacion de acido 6-(3-cloro-2-fluorbencil)-1-[(s)-1-hidroximetil-2-metilpropil]-7-metoxi-4-oxo-1, 4-dihidroquinolon-3-carboxilico como inhibidores de integrasa del hiv e intermediarios de sintesis del mismo y composiciones que lo comprenden.
US8658183B2 (en) 2007-08-09 2014-02-25 Taigen Biotechnology Company, Ltd. Antimicrobial parenteral formulation
AR068403A1 (es) * 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
KR20110044168A (ko) 2008-07-01 2011-04-28 타이젠 바이오테크놀러지 컴퍼니 리미티드 항생제 내성 세균 감염의 치료
BR112015002275A2 (pt) 2012-08-03 2017-07-04 Gilead Sciences Inc processos e intermediários para a preparação de inibidores da integrase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10503521A (ja) * 1994-08-02 1998-03-31 ザ、プロクター、エンド、ギャンブル、カンパニー キノロニルラクタム抗微生物剤の製造方法及び新規中間化合物
WO1996004247A1 (en) * 1994-08-02 1996-02-15 The Procter & Gamble Company Process for making antimicrobial compounds

Also Published As

Publication number Publication date
PL363355A1 (en) 2004-11-15
CN1481365A (zh) 2004-03-10
JP4417007B2 (ja) 2010-02-17
HUP0303991A3 (en) 2012-09-28
NZ525569A (en) 2004-09-24
JP2004515542A (ja) 2004-05-27
CA2427831C (en) 2009-08-18
HUP0303991A2 (hu) 2004-04-28
AU2002229057B2 (en) 2005-04-21
CN1232508C (zh) 2005-12-21
PL207394B1 (pl) 2010-12-31
DE60112325T2 (de) 2006-05-24
AU2905702A (en) 2002-06-24
JP2010001315A (ja) 2010-01-07
EP1343766B1 (en) 2005-07-27
WO2002048113A1 (en) 2002-06-20
DE60112325D1 (de) 2005-09-01
ES2247190T3 (es) 2006-03-01
KR100603163B1 (ko) 2006-07-24
DK1343766T3 (da) 2005-10-31
NO20032667D0 (no) 2003-06-12
KR20030063420A (ko) 2003-07-28
EP1343766A1 (en) 2003-09-17
IL155677A (en) 2009-02-11
CA2427831A1 (en) 2002-06-20
IL155677A0 (en) 2003-11-23
ATE300522T1 (de) 2005-08-15
MXPA03005338A (es) 2003-10-06
NO20032667L (no) 2003-08-14
CZ20031379A3 (cs) 2003-11-12
NO325236B1 (no) 2008-03-03

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2258 DE 15/04/2014.