BR0116229A - Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas - Google Patents
Etapa de processo de ciclização na fabricação de quinolonas e naftiridinasInfo
- Publication number
- BR0116229A BR0116229A BR0116229-2A BR0116229A BR0116229A BR 0116229 A BR0116229 A BR 0116229A BR 0116229 A BR0116229 A BR 0116229A BR 0116229 A BR0116229 A BR 0116229A
- Authority
- BR
- Brazil
- Prior art keywords
- quinolones
- manufacture
- process step
- naphthyridines
- cyclization process
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 150000005054 naphthyridines Chemical class 0.000 title 1
- 150000007660 quinolones Chemical class 0.000 title 1
- 238000007363 ring formation reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
"ETAPA DE PROCESSO DE CICLIZAçãO NA FABRICAçãO DE QUINOLONAS E NAFTIRIDINAS". A presente invenção refere-se a um processo de fabricação de um composto que tem uma estrutura de acordo com a Fórmula (I): sendo que o processo compreende a reação de um ou mais reagentes de organossilícios com um composto que tem a estrutura da fórmula (A).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25563300P | 2000-12-14 | 2000-12-14 | |
PCT/US2001/048536 WO2002048113A1 (en) | 2000-12-14 | 2001-12-07 | Cyclization process step in the making of quinolones and naphthyridines |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0116229A true BR0116229A (pt) | 2003-11-04 |
Family
ID=22969207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0116229-2A BR0116229A (pt) | 2000-12-14 | 2001-12-07 | Etapa de processo de ciclização na fabricação de quinolonas e naftiridinas |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1343766B1 (pt) |
JP (2) | JP4417007B2 (pt) |
KR (1) | KR100603163B1 (pt) |
CN (1) | CN1232508C (pt) |
AT (1) | ATE300522T1 (pt) |
AU (2) | AU2905702A (pt) |
BR (1) | BR0116229A (pt) |
CA (1) | CA2427831C (pt) |
CZ (1) | CZ20031379A3 (pt) |
DE (1) | DE60112325T2 (pt) |
DK (1) | DK1343766T3 (pt) |
ES (1) | ES2247190T3 (pt) |
HU (1) | HUP0303991A3 (pt) |
IL (2) | IL155677A0 (pt) |
MX (1) | MXPA03005338A (pt) |
NO (1) | NO325236B1 (pt) |
NZ (1) | NZ525569A (pt) |
PL (1) | PL207394B1 (pt) |
WO (1) | WO2002048113A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100735587B1 (ko) * | 2002-08-05 | 2007-07-04 | 더 프록터 앤드 갬블 캄파니 | 퀴놀론계 항생제 중간체의 제조 방법 |
US6803469B2 (en) * | 2002-08-05 | 2004-10-12 | The Procter & Gamble Company | Process for preparing quinolone antibiotic intermediates |
EP2272516A3 (en) * | 2002-11-20 | 2011-03-16 | Japan Tobacco, Inc. | 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor |
US7402674B2 (en) | 2004-01-31 | 2008-07-22 | Sanofi-Aventis Deutschland Gmbh, | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments |
EP1992607B9 (en) | 2006-03-06 | 2015-07-01 | Japan Tobacco, Inc. | Method for producing 4-oxoquinoline compound |
IN2014CN00532A (pt) | 2006-03-06 | 2015-04-03 | Japan Tobacco Inc | |
AP3004A (en) * | 2006-09-12 | 2014-10-31 | Gilead Sciences Inc | Process and intermediates for preparing integrase inhibitors |
US8658183B2 (en) | 2007-08-09 | 2014-02-25 | Taigen Biotechnology Company, Ltd. | Antimicrobial parenteral formulation |
AR068403A1 (es) | 2007-09-11 | 2009-11-18 | Gilead Sciences Inc | Proceso e intermediarios para la preparacion de inhibidores de integrasa |
WO2010002415A1 (en) | 2008-07-01 | 2010-01-07 | Taigen Biotechnology Co., Ltd. | Treatment of antibiotic-resistant bacteria infection |
US8877931B2 (en) | 2012-08-03 | 2014-11-04 | Gilead Sciences, Inc. | Process and intermediates for preparing integrase inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10503521A (ja) * | 1994-08-02 | 1998-03-31 | ザ、プロクター、エンド、ギャンブル、カンパニー | キノロニルラクタム抗微生物剤の製造方法及び新規中間化合物 |
NZ290721A (en) * | 1994-08-02 | 1999-03-29 | Procter & Gamble | Process for making quinolone-containing antimicrobial compounds |
-
2001
- 2001-12-07 CN CNB018207146A patent/CN1232508C/zh not_active Expired - Lifetime
- 2001-12-07 DK DK01990192T patent/DK1343766T3/da active
- 2001-12-07 DE DE60112325T patent/DE60112325T2/de not_active Expired - Lifetime
- 2001-12-07 AU AU2905702A patent/AU2905702A/xx active Pending
- 2001-12-07 JP JP2002549644A patent/JP4417007B2/ja not_active Expired - Fee Related
- 2001-12-07 EP EP01990192A patent/EP1343766B1/en not_active Expired - Lifetime
- 2001-12-07 NZ NZ525569A patent/NZ525569A/en not_active IP Right Cessation
- 2001-12-07 BR BR0116229-2A patent/BR0116229A/pt not_active IP Right Cessation
- 2001-12-07 WO PCT/US2001/048536 patent/WO2002048113A1/en active IP Right Grant
- 2001-12-07 AT AT01990192T patent/ATE300522T1/de active
- 2001-12-07 AU AU2002229057A patent/AU2002229057B2/en not_active Ceased
- 2001-12-07 KR KR1020037007905A patent/KR100603163B1/ko not_active IP Right Cessation
- 2001-12-07 IL IL15567701A patent/IL155677A0/xx active IP Right Grant
- 2001-12-07 PL PL363355A patent/PL207394B1/pl not_active IP Right Cessation
- 2001-12-07 HU HU0303991A patent/HUP0303991A3/hu unknown
- 2001-12-07 CZ CZ20031379A patent/CZ20031379A3/cs unknown
- 2001-12-07 ES ES01990192T patent/ES2247190T3/es not_active Expired - Lifetime
- 2001-12-07 CA CA002427831A patent/CA2427831C/en not_active Expired - Fee Related
- 2001-12-07 MX MXPA03005338A patent/MXPA03005338A/es active IP Right Grant
-
2003
- 2003-04-30 IL IL155677A patent/IL155677A/en not_active IP Right Cessation
- 2003-06-12 NO NO20032667A patent/NO325236B1/no not_active IP Right Cessation
-
2009
- 2009-10-05 JP JP2009231801A patent/JP2010001315A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2002229057B2 (en) | 2005-04-21 |
IL155677A0 (en) | 2003-11-23 |
WO2002048113A1 (en) | 2002-06-20 |
JP2010001315A (ja) | 2010-01-07 |
DE60112325D1 (de) | 2005-09-01 |
CA2427831A1 (en) | 2002-06-20 |
ES2247190T3 (es) | 2006-03-01 |
HUP0303991A3 (en) | 2012-09-28 |
IL155677A (en) | 2009-02-11 |
JP2004515542A (ja) | 2004-05-27 |
DE60112325T2 (de) | 2006-05-24 |
HUP0303991A2 (hu) | 2004-04-28 |
MXPA03005338A (es) | 2003-10-06 |
EP1343766A1 (en) | 2003-09-17 |
KR100603163B1 (ko) | 2006-07-24 |
AU2905702A (en) | 2002-06-24 |
CN1232508C (zh) | 2005-12-21 |
CN1481365A (zh) | 2004-03-10 |
PL363355A1 (en) | 2004-11-15 |
CA2427831C (en) | 2009-08-18 |
NZ525569A (en) | 2004-09-24 |
KR20030063420A (ko) | 2003-07-28 |
ATE300522T1 (de) | 2005-08-15 |
NO20032667L (no) | 2003-08-14 |
PL207394B1 (pl) | 2010-12-31 |
EP1343766B1 (en) | 2005-07-27 |
JP4417007B2 (ja) | 2010-02-17 |
NO325236B1 (no) | 2008-03-03 |
DK1343766T3 (da) | 2005-10-31 |
NO20032667D0 (no) | 2003-06-12 |
CZ20031379A3 (cs) | 2003-11-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07F | Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette] |
Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2258 DE 15/04/2014. |