BR0111458A - Métodos de tratamento ou profilaxia de condição inflamatória, de imunoproteção e de imunopotencialização de um indivìduo, composição, computador e produto de programa de computador - Google Patents

Métodos de tratamento ou profilaxia de condição inflamatória, de imunoproteção e de imunopotencialização de um indivìduo, composição, computador e produto de programa de computador

Info

Publication number
BR0111458A
BR0111458A BR0111458-1A BR0111458A BR0111458A BR 0111458 A BR0111458 A BR 0111458A BR 0111458 A BR0111458 A BR 0111458A BR 0111458 A BR0111458 A BR 0111458A
Authority
BR
Brazil
Prior art keywords
chemical
treatment
inflammatory condition
prophylaxis
computer
Prior art date
Application number
BR0111458-1A
Other languages
English (en)
Inventor
James Harrison Aylward
Peter Gordon Parsons
Andreas Suhrbier
Kathleen Anne Turner
Original Assignee
Peplin Research Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peplin Research Pty Ltd filed Critical Peplin Research Pty Ltd
Publication of BR0111458A publication Critical patent/BR0111458A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)

Abstract

"MéTODOS DE TRATAMENTO OU PROFILAXIA DE CONDIçãO INFLAMATóRIA, DE IMUNOPROTEçãO E DE IMUNOPOTENCIALIZAçãO DE UM INDIVìDUO, COMPOSIçãO, COMPUTADOR E PRODUTO DE PROGRAMA DE COMPUTADOR". A presente invenção refere-se, de forma geral, a agentes químicos úteis no tratamento e na profilaxia de condições inflamatórias ou na melhoria de sintomas resultantes ou facilitados por condição inflamatória nos mamíferos, inclusive humanos e primatas, animais não mamíferos e espécies de aves. Mais especificamente, a presente invenção proporciona um agente químico da família dos diterpenos macrocíclicos, cuja obtenção é possível a partir de um membro da família de plantas Euforbiáceas ou de seus derivados botânicos ou de horticultura ou de derivados ou análogos químicos ou formas quimicamente sintéticas dos agentes usados no tratamento ou na profilaxia de condição inflamatória ou na melhoria de sintomas resultantes ou facilitados por condição inflamatória nos mamíferos, animais e aves. A presente invenção também contempla um método para profilaxia ou tratamento de indivíduos mamíferos, animais e aves que exibem condições inflamatórias que incluem condições inflamatórias crónicas ou transitórias ou para melhoria dos sintomas de uma condição inflamatória pela administração tópica ou sistêmica de diterpenos macrocíclicos, passíveis de serem obtidos a partir de um membro da família de plantas Euforbiáceas ou de seus derivados botânicos ou de horticultura ou de um derivado, análogo químico ou forma quimicamente sintética do agente. O agente químico da presente invenção pode estar na forma de um composto purificado, de uma mistura de compostos, de uma forma precursora de um ou mais dos compostos capazes de causar transformação química num agente terapeuticamente ativo ou estar na forma de uma fração química, subtração, preparação ou extrato da planta.
BR0111458-1A 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de condição inflamatória, de imunoproteção e de imunopotencialização de um indivìduo, composição, computador e produto de programa de computador BR0111458A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPQ8017A AUPQ801700A0 (en) 2000-06-07 2000-06-07 Enzyme and viral activation
PCT/AU2001/000680 WO2001093885A1 (en) 2000-06-07 2001-06-07 Therapeutic agents - ii

Publications (1)

Publication Number Publication Date
BR0111458A true BR0111458A (pt) 2003-06-24

Family

ID=3822089

Family Applications (3)

Application Number Title Priority Date Filing Date
BR0111423-9A BR0111423A (pt) 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de condição inflamatória e de imunoproteção de um indivìduo, composição, computador e produto de programa de computador, processo de separação de diterpenos macrocìclicos de uma biomassa e uso de agente quìmico ou derivado ou análogo quìmico daquele
BR0111458-1A BR0111458A (pt) 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de condição inflamatória, de imunoproteção e de imunopotencialização de um indivìduo, composição, computador e produto de programa de computador
BR0111375-5A BR0111375A (pt) 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de uma condição ou distúrbio relacionada com pkc, de modulação da expressão de uma seq ência genética e de estimulação da ativação ou função de um promotor, computador e produto de programa de computador

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR0111423-9A BR0111423A (pt) 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de condição inflamatória e de imunoproteção de um indivìduo, composição, computador e produto de programa de computador, processo de separação de diterpenos macrocìclicos de uma biomassa e uso de agente quìmico ou derivado ou análogo quìmico daquele

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0111375-5A BR0111375A (pt) 2000-06-07 2001-06-07 Métodos de tratamento ou profilaxia de uma condição ou distúrbio relacionada com pkc, de modulação da expressão de uma seq ência genética e de estimulação da ativação ou função de um promotor, computador e produto de programa de computador

Country Status (8)

Country Link
US (6) US20030195168A1 (pt)
EP (3) EP1296697A4 (pt)
JP (3) JP5822417B2 (pt)
AU (1) AUPQ801700A0 (pt)
BR (3) BR0111423A (pt)
CA (3) CA2411596C (pt)
NZ (3) NZ522425A (pt)
WO (3) WO2001093884A1 (pt)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO864097A0 (en) 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
AUPQ801700A0 (en) 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
AUPQ923100A0 (en) 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
EP2189473A3 (en) 2000-10-27 2010-08-11 Novartis Vaccines and Diagnostics S.r.l. Nucleic and proteins from streptococcus groups A & B
US20050065205A1 (en) 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
EP1597348A4 (en) * 2002-08-26 2010-03-31 Novartis Vaccines & Diagnostic GENES OF STREPTOCOCCUS PRESERVED OR SPECIFIC
US7220357B2 (en) * 2003-07-24 2007-05-22 Teva Gyógyszergyár Zártkörúen Múkó´dó´Résvénytársaság Method of purifying macrolides
CA2532369C (en) 2003-07-31 2016-07-26 Chiron Corporation Immunogenic compositions for streptococcus pyogenes
US8945589B2 (en) * 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
US20050070565A1 (en) * 2003-09-26 2005-03-31 Arnsten Amy F.T. Chelerythrine, analogs thereof and their use in the treatment of bipolar disorder and other cognitive disorders
TW200538181A (en) 2004-05-18 2005-12-01 Brni Neurosciences Inst Treatment of depressive disorders
US20060165716A1 (en) 2004-07-29 2006-07-27 Telford John L Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
DE102004044428A1 (de) * 2004-09-14 2006-03-30 Toximed Gmbh Verfahren und pharmazeutischer Wirkstoff zur Bekämpfung von Plasmodien
CA2583803C (en) * 2004-10-08 2014-11-25 Giuliano Bensi Immunogenic and therapeutic compositions for streptococcus pyogenes
EP1807038A1 (en) * 2004-11-03 2007-07-18 Cognis France, S.A.S. An extract of a plant belonging to the genus plukenetia volubilis and its cosmetic use
US8106092B2 (en) * 2004-12-13 2012-01-31 Leo Laboratories Limited Treatment of solid cancers
US20090076132A1 (en) * 2005-03-11 2009-03-19 Gary Pekoe Antiviral compositions and methods of treatment
US20060204600A1 (en) * 2005-03-11 2006-09-14 Paul Konz Dragon's blood anti-viral materials and methods
WO2007016202A1 (en) 2005-07-29 2007-02-08 Blanchette Rockefeller Neurosciences Institute Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory
JP2009516651A (ja) * 2005-11-14 2009-04-23 ペプリン リサーチ プロプライエタリー リミティッド 癌を治療するための他の薬剤と組み合わせたアンゲロイル置換インゲナンの使用
US20090215884A1 (en) * 2005-11-25 2009-08-27 Peplin Research Pty Ltd. Method for wound healing
GB0525680D0 (en) 2005-12-16 2006-01-25 Peplin Ltd Therapeutic compositions
PL2054431T3 (pl) * 2006-06-09 2012-07-31 Novartis Ag Konformery adhezyn bakteryjnych
EP2094297A2 (en) * 2006-10-30 2009-09-02 Novartis AG Immunogenic and therapeutic compositions for streptococcus pyogenes
CA2873179A1 (en) 2007-02-09 2008-08-21 Blanchette Rockefeller Neurosciences Institute Use of bryostatins and neristatins in the treatment of cognitive impairment due to head trauma
DK2152261T3 (en) * 2007-04-30 2016-03-07 Leo Lab Ltd TREATMENT OF virus-induced INJURY
US8287885B2 (en) 2007-09-12 2012-10-16 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
KR100926408B1 (ko) 2007-10-09 2009-11-12 고려대학교 산학협력단 감마허피스바이러스 재활성을 유도하는 감수 및 이를포함하는 약제학적 조성물
WO2009081274A2 (en) 2007-12-21 2009-07-02 Novartis Ag Mutant forms of streptolysin o
KR101089314B1 (ko) 2010-06-07 2011-12-02 한국식품연구원 유포비아스테로이드를 유효성분으로 함유하는 비만 예방, 치료 또는 개선용 조성물
CN107011167A (zh) 2010-07-20 2017-08-04 利奥实验室有限公司 制备巨大戟二萜醇‑3‑当归酸酯的方法
WO2012080466A2 (en) 2010-12-17 2012-06-21 Leo Pharma A/S Ingenols for treating seborrheic keratosis
NZ710133A (en) * 2010-12-22 2016-08-26 Leo Lab Ltd Ingenol-3-acylates iii and ingenol-3-carbamates
AU2011348638B2 (en) 2010-12-22 2015-05-21 Leo Laboratories Limited 3-acyl-ingenols II
BR112013015877A2 (pt) 2010-12-22 2018-06-05 Leo Laboratories Ltd composto, uso de um composto, métodos de prevenção. tratamento, melhora ou profilaxia de distúrbios fisiológicos ou doenças, e de tratamento ou melhora de indicações cosméticas, e, composição farmacêutica.
CN102977019A (zh) * 2011-09-06 2013-03-20 高峰 汉源乌头中一种新型c19二萜生物碱及其在制备抗肿瘤药物中的应用
JP2013063938A (ja) * 2011-09-20 2013-04-11 Kao Corp メラニン産生促進剤
KR101406201B1 (ko) * 2011-10-19 2014-06-12 한국생명공학연구원 인제난 타입의 디테르펜 화합물 및 이를 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물
WO2013088375A1 (en) 2011-12-12 2013-06-20 Leo Laboratories Limited A topical composition comprising an ingenol derivative and an oily solvent
EP2790672A1 (en) 2011-12-12 2014-10-22 Leo Laboratories Limited Gel compositions
US20140343141A1 (en) 2011-12-12 2014-11-20 Leo Laboratories Limited Topical composition comprising an ingenol derivative and a surfactant-cosolvent mixture
US20130251782A1 (en) 2012-03-22 2013-09-26 Leo Laboratories Limited Topical application of ingenol mebutate with occlusion
WO2013182688A1 (en) 2012-06-08 2013-12-12 Leo Laboratories Limited A topical gel composition comprising an ingenol derivative and a solvent mixture
US9624157B2 (en) 2012-07-16 2017-04-18 Leo Laboratories Limited Process for the preparation of ingenol-3-angelate from 20-deoxy-ingenol
CN103086882B (zh) * 2013-02-05 2015-04-15 中国科学院新疆理化技术研究所 对叶大戟果实中的大环二萜类化合物及其制备方法和用途
US9526714B2 (en) 2014-03-24 2016-12-27 Leo Laboratories Limited Method for treating skin lesions with ingenol mebutate
EP3145903A4 (en) 2014-05-23 2018-01-03 Alphora Research Inc. A continuous flow process for the preparation of ingenol-3-mebutate
WO2016022358A1 (en) 2014-08-08 2016-02-11 The Regents Of The University Of California Compositions and methods for reactivating latent viral infections
CN104649901B (zh) * 2015-02-09 2017-03-29 中国科学院昆明植物研究所 一种治疗光化性角化病的原料药物巨大戟醇甲基丁烯酸酯的制备方法
KR101735784B1 (ko) * 2015-06-15 2017-05-15 대한민국(환경부 국립생물자원관장) 트리고노스테몬 레이디오이데스 추출물을 이용한 항염증용 조성물
KR101735785B1 (ko) 2015-06-15 2017-05-15 대한민국(환경부 국립생물자원관장) 트리고노스테몬 레이디오이데스 추출물을 이용한 항알러지용 조성물
CN105348095A (zh) * 2015-12-07 2016-02-24 西宁意格知识产权咨询服务有限公司 一种新的二萜类化合物及其制备方法和医药用途
US10275356B2 (en) * 2015-12-11 2019-04-30 Quanta Computer Inc. Component carrier with converter board
KR101755017B1 (ko) 2016-08-10 2017-07-06 호서대학교 산학협력단 선녀배(Dudleya brittonii) 추출물의 제조방법 및 선녀배 추출물을 유효성분으로 함유하는 항암 또는 항산화용 조성물
JP7154539B2 (ja) * 2016-08-18 2022-10-18 国立大学法人 奈良先端科学技術大学院大学 免疫調節剤
US10425485B2 (en) * 2016-11-21 2019-09-24 Cisco Technology, Inc. Integrating information centric networking (ICN) over low power and lossy networks (LLNs)
CN109912419A (zh) * 2017-12-13 2019-06-21 复旦大学 巨大戟烷型二萜及其在制备抗艾滋病毒药物中的用途
KR101978915B1 (ko) * 2018-08-08 2019-05-15 애경산업(주) 포인세티아 추출물을 포함하는 여드름 예방 및 개선용 조성물
KR102508255B1 (ko) * 2021-02-15 2023-03-09 연세대학교 산학협력단 비정형 pkc 활성화제를 함유하는 당 조절용 조성물

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809749A (en) 1971-03-05 1974-05-07 Amazon Natural Drug Co Topical pharmaceutical composition and method employing sap from the tree croton lechleri
DE2902506A1 (de) 1979-01-23 1980-07-24 Deutsches Krebsforsch Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel
US4418064A (en) * 1982-09-29 1983-11-29 The United States Of America As Represented By The Secretary Of Agriculture Chemotherapeutically active maytansinoids: treflorine, trenudine, and N-methyltrenudone
US4560774A (en) * 1982-11-17 1985-12-24 Arizona State University Macrocyclic lactones
US5886019A (en) * 1986-06-11 1999-03-23 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. F.
US5145842A (en) * 1986-06-11 1992-09-08 Alder Research Center Limited Partnership Protein kinase c. modulators. d.
IL82811A0 (en) 1986-06-11 1987-12-20 Alder Res Center Corp Anti-inflammatory compositions containing methanol derivatives and novel compounds contained therein
US5750568A (en) * 1986-06-11 1998-05-12 Procyon Pharmaceuticals, Inc. Protein kinase C Modulators. L.
US5643948A (en) * 1986-06-11 1997-07-01 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. K.
US5891906A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Polyacetate-derived phorboids having anti-inflammatory and other uses
US5891870A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Protein kinase C modulators Q
US5886017A (en) * 1986-06-11 1999-03-23 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. E.
US5962498A (en) 1986-06-11 1999-10-05 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US5716968A (en) 1986-06-11 1998-02-10 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. H.
DE3805965A1 (de) 1988-02-25 1989-09-07 Tamas Geb Szenasi Eszter Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe
DE4102054A1 (de) 1991-01-24 1992-07-30 Geb Szenasi Tamas Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe
US5317009A (en) * 1991-08-26 1994-05-31 New York University Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof
HU208790B (en) 1991-12-05 1994-01-28 Tamas Process for producing pharmaceutical compositions against arc and aids, comprising euphorbia hirta l. plant or its parts or their extracts
CN1047084C (zh) 1993-03-30 1999-12-08 刘振宪 人参口服液及其制造方法
US6593371B1 (en) * 1993-05-19 2003-07-15 Jeff J. Staggs Treatment for wart and related disorders
CN1048164C (zh) 1993-08-24 2000-01-12 吴雪姣 复方菝葜口服液
JP2913451B2 (ja) 1994-06-22 1999-06-28 株式会社イナックス 防水パンの高さ調整構造
JPH08245505A (ja) 1994-09-09 1996-09-24 Tosoh Corp ジテルペン誘導体、その製造法及びそれを有効成分として含有する抗腫瘍剤
JPH08176004A (ja) 1994-12-21 1996-07-09 Lion Corp 生体老化防止剤及び皮膚用組成物
JPH08176002A (ja) 1994-12-27 1996-07-09 Kao Corp 細胞接着抑制剤
US5874464A (en) * 1995-01-13 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Conformationally constrained diacylglycerol analogues
CN1070372C (zh) 1995-02-15 2001-09-05 赵国强 强力抗癌膏及其制造方法
WO1997015575A1 (en) 1995-10-27 1997-05-01 Procyon Pharmaceuticals, Inc. Protein kinase c modulators. y.
CN1058620C (zh) 1995-11-12 2000-11-22 卢颖 一种治疗癌症的外用中成药及配备生产工艺
US5749111A (en) * 1996-02-14 1998-05-12 Teksource, Lc Gelatinous cushions with buckling columns
US5932613A (en) * 1996-07-03 1999-08-03 Millennium Pharmaceuticals, Inc. Anticancer agents
US6329459B1 (en) * 1996-09-23 2001-12-11 Bridgestone Corporation Extended syndiotactic polystyrene-elastomeric block copolymers
AUPO864097A0 (en) * 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
WO1999009884A1 (fr) * 1997-08-26 1999-03-04 Seiko Epson Corporation Procede et appareil de mesure, de detection et de diagnostic d'un signal impulsionnel, de la fonction cardiaque et de l'intensite de mouvement
US6228939B1 (en) * 1999-05-19 2001-05-08 Bridgestone Corporation Thermoreversible gels comprising near gelation polymers
EP1218420B1 (en) * 1999-08-16 2005-01-26 Dow Global Technologies Inc. Hydrogenated block copolymers and optical media discs produced therefrom
JP2001139468A (ja) * 1999-11-11 2001-05-22 Lead Chemical Co Ltd 抗ウイルス作用を有するホルボール誘導体
AUPQ801700A0 (en) 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
AUPQ923100A0 (en) 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
JP4880816B2 (ja) 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
US6923993B2 (en) * 2001-12-12 2005-08-02 Nicholas J. Donato Process of isolating extract from the Euphorbia obesa plant and methods for using the same
JP3935360B2 (ja) 2002-01-22 2007-06-20 丸善製薬株式会社 ヒアルロン酸産生促進剤並びに皮膚化粧料及び美容用飲食品
EP1676132B1 (en) * 2003-10-21 2014-01-22 Cedars-Sinai Medical Center Combination of chemotherapy and administration of glioma-antigen-pulsed dendritic cells in the treatment of glioma
EA009669B1 (ru) 2004-01-01 2008-02-28 Панацея Биотек Лтд. Фармацевтические композиции, содержащие экстракт euphorbia prostrata
US8106092B2 (en) 2004-12-13 2012-01-31 Leo Laboratories Limited Treatment of solid cancers
US7378455B2 (en) * 2005-06-30 2008-05-27 General Electric Company Molding composition and method, and molded article
BRPI0504797B1 (pt) * 2005-10-27 2020-02-04 Pele Nova Biotecnologia S A formulação tópica, método de tratamento cosmético para rejuvenescimento da pele, método de tratamento cosmético e uso de uma formulação
JP2009516651A (ja) 2005-11-14 2009-04-23 ペプリン リサーチ プロプライエタリー リミティッド 癌を治療するための他の薬剤と組み合わせたアンゲロイル置換インゲナンの使用
US20090215884A1 (en) 2005-11-25 2009-08-27 Peplin Research Pty Ltd. Method for wound healing
GB0525680D0 (en) 2005-12-16 2006-01-25 Peplin Ltd Therapeutic compositions
DK2152261T3 (en) 2007-04-30 2016-03-07 Leo Lab Ltd TREATMENT OF virus-induced INJURY

Also Published As

Publication number Publication date
EP1296698B1 (en) 2015-01-14
JP2003535137A (ja) 2003-11-25
EP1296698A4 (en) 2005-02-16
CA2411642A1 (en) 2001-12-13
WO2001093884A1 (en) 2001-12-13
CA2411642C (en) 2011-05-17
CA2411596C (en) 2014-08-19
EP1296699A4 (en) 2005-02-16
US20110213002A1 (en) 2011-09-01
JP5822417B2 (ja) 2015-11-24
EP1296699B1 (en) 2015-08-12
JP2003535138A (ja) 2003-11-25
NZ522427A (en) 2004-05-28
US20030166613A1 (en) 2003-09-04
BR0111375A (pt) 2003-06-10
EP1296697A4 (en) 2005-02-16
JP5822418B2 (ja) 2015-11-24
NZ522425A (en) 2004-05-28
JP5339662B2 (ja) 2013-11-13
EP1296699A1 (en) 2003-04-02
AUPQ801700A0 (en) 2000-06-29
US7838555B2 (en) 2010-11-23
US20030195168A1 (en) 2003-10-16
CA2411726A1 (en) 2001-12-13
US20100048698A1 (en) 2010-02-25
EP1296697A1 (en) 2003-04-02
CA2411726C (en) 2011-09-20
US20030171337A1 (en) 2003-09-11
US9314458B2 (en) 2016-04-19
BR0111423A (pt) 2003-04-29
EP1296698A1 (en) 2003-04-02
WO2001093885A1 (en) 2001-12-13
WO2001093883A1 (en) 2001-12-13
JP2003535136A (ja) 2003-11-25
US20050209192A1 (en) 2005-09-22
US7449492B2 (en) 2008-11-11
NZ522426A (en) 2004-05-28
CA2411596A1 (en) 2001-12-13

Similar Documents

Publication Publication Date Title
BR0111458A (pt) Métodos de tratamento ou profilaxia de condição inflamatória, de imunoproteção e de imunopotencialização de um indivìduo, composição, computador e produto de programa de computador
Mahajan et al. A phytopharmacological overview on Ocimum species with special emphasis on Ocimum sanctum
EP1713490B1 (en) Compositions for the treatment of atopic dermatitis, skin allergic conditions and acne
Okeniyi et al. Phytochemical screening, cytotoxicity, antioxidant and antimicrobial activities of stem and leave extracts of Euphorbia heterophylla
Patil et al. Hepatoprotective activity of Mentha arvensis Linn. leaves against CCl4 induced liver damage in rats
Varma et al. The antiplaque efficacy of two herbal-based toothpastes: a clinical intervention
KR950000142A (ko) 피부질환치료용 약제조성물 제조에 사용되는 히드록시산함유 l-카르니틴에스테르 및 아실 l-카르니틴에스테르의 용도
Hussain et al. Anti-inflammatory and antioxidant activities of Cordia dichotoma Forst
Yalcin et al. Inhibition of catechol-O-methyltransferase (COMT) by some plant-derived alkaloids and phenolics
US20120316144A1 (en) Antifungal agent
Germann et al. Antioxidative properties of the gastrointestinal phytopharmaceutical remedy STW 5 (Iberogast®)
Adedoyin et al. Cytotoxicity, antioxidant and antimicrobial activities of essential oil extracted from Euphorbia heterophylla plant
US11109607B2 (en) Oil-based compositions for enhancing oral health and general wellness in humans
Bosly Larvicidal potential of Thuja orientalis leaves and fruits extracts against Culex pipiens (Diptera: Culicidae)
Selles et al. Chemical composition, antioxidant and in vitro antibacterial activities of essential oils of mentha spicata leaf from tiaret area (Algeria)
Oghenejoboh et al. Chemical composition, cytotoxicity and antioxidant activities of essential oils of Parquetina nigrescens (Afz.) bullock from ibadan, Nigeria
LA BASY et al. A Review: Activity Study of Itchy Leaves (Laportea decumana Roxb Wadd) as a Medicinal Plant.
Ramezani et al. Effect of Geum kokanicum total extract on induced nociception and inflammation in male mice
Antia et al. Wound healing, phytochemical and antimicrobial properties of Luffa cylindrica (Linn.) seed extracts
IT201800010241A1 (it) Composizione contenente cannella per il trattamento coadiuvante di affezioni delle vie respiratorie e di malattie da raffreddamento in genere
Chebbac et al. Research Article Chemical Analysis and Antioxidant and Antimicrobial Activity of Essential oils from Artemisia negrei L. against Drug-Resistant Microbes
NDUKWE et al. Afzelia africana Seed Extract: Toxicity, Antidiarrhoeal and Chemical Assays.
Zulkurnain et al. The Phytochemical and Pharmacological Effects of Hibiscus rosa-sinensis: A Review.
Andavarapu Assessment of Antibacterial, Anti-Inflammatory and Antioxidant Activity of Allium Sativum (Garlic) Cloves Extracts–An in Vitro Study
MA51937B1 (fr) Formulation médicale contre staphylococcus aureus résistant à la méticilline responsable des infections invasives

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/455 (2006.01), A61K 31/22 (2006.01), A61K