BR0109442A - Processo para a preparação de derivados de 4,6-bis(arilóxi) pirimidina assimétricos - Google Patents

Processo para a preparação de derivados de 4,6-bis(arilóxi) pirimidina assimétricos

Info

Publication number
BR0109442A
BR0109442A BR0109442-4A BR0109442A BR0109442A BR 0109442 A BR0109442 A BR 0109442A BR 0109442 A BR0109442 A BR 0109442A BR 0109442 A BR0109442 A BR 0109442A
Authority
BR
Brazil
Prior art keywords
asymmetric
bis
preparation
pyrimidine derivatives
aryloxy
Prior art date
Application number
BR0109442-4A
Other languages
English (en)
Other versions
BR0109442B1 (pt
Inventor
Holger Weintritt
Uwe Stelzer
Herbert Gayer
Walter Huebsch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR0109442A publication Critical patent/BR0109442A/pt
Publication of BR0109442B1 publication Critical patent/BR0109442B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE DERIVADOS DE 4,6-BIS(ARILóXI)PIRIMIDINA ASSIMéTRICOS". A invenção refere-se a um novo processo para a preparação de derivados de 4,6-bis(arilóxi)pirimidina conhecidos, assimétricos da fórmula geral (1), na qual Ar^ 1^ representa em cada caso arila ou heterociclila substituídas ou não substituídas, X representa hidrogênio, flúor, cloro ou bromo, e L^ 1^ - L^ 5^ possuem os significados dados na reivindicação 1, com adição de diazabiciclo[2.2.2]octano (DABCO).
BRPI0109442-4A 2000-03-24 2001-03-12 processo para a preparaÇço de derivados de 4,6-bis(arilàxi)pirimidina assimÉtricos. BR0109442B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10014607A DE10014607A1 (de) 2000-03-24 2000-03-24 Verfahren zur Herstellung von unsymmetrischen 4,6-Bis(aryloxy pyrimidin-Derivaten
PCT/EP2001/002731 WO2001072719A1 (de) 2000-03-24 2001-03-12 Verfahren zur herstellung von unsymmetrischen 4,6-bis(aryloxy)pyrimidin-derivaten

Publications (2)

Publication Number Publication Date
BR0109442A true BR0109442A (pt) 2002-12-10
BR0109442B1 BR0109442B1 (pt) 2013-02-19

Family

ID=7636165

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0109442-4A BR0109442B1 (pt) 2000-03-24 2001-03-12 processo para a preparaÇço de derivados de 4,6-bis(arilàxi)pirimidina assimÉtricos.

Country Status (17)

Country Link
US (1) US6734304B2 (pt)
EP (1) EP1268446B1 (pt)
JP (1) JP5008242B2 (pt)
KR (1) KR100758615B1 (pt)
CN (1) CN1280278C (pt)
AR (1) AR034693A1 (pt)
AT (1) ATE483691T1 (pt)
AU (1) AU2001242454A1 (pt)
BR (1) BR0109442B1 (pt)
DE (2) DE10014607A1 (pt)
DK (1) DK1268446T3 (pt)
ES (1) ES2353271T3 (pt)
HU (1) HUP0300267A3 (pt)
IL (1) IL151678A (pt)
MX (1) MXPA02009286A (pt)
TW (1) TWI296621B (pt)
WO (1) WO2001072719A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1758456B1 (de) * 2004-06-17 2008-03-05 Basf Se Verwendung von (e)-5-(4-chlorbenzyliden)-2,2-dimethyl-1-(1h-1,2,4-triazol-1-ylmethyl)cyclopentanol zur bekämpfung des rostbefalls an sojapflanzen
GB0508422D0 (en) * 2005-04-26 2005-06-01 Syngenta Ltd Chemical process
JP5061565B2 (ja) 2006-04-24 2012-10-31 住友化学株式会社 ピリミジン化合物の新規製造方法
US7847111B2 (en) * 2006-06-19 2010-12-07 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III
GB0619942D0 (en) * 2006-10-09 2006-11-15 Syngenta Ltd Chemical process
GB0619941D0 (en) * 2006-10-09 2006-11-15 Syngenta Ltd Chemical process
JP2015083541A (ja) * 2012-02-03 2015-04-30 アグロカネショウ株式会社 対称性４，６−ビス（アリールオキシ）ピリミジン化合物の製造方法
TWI621614B (zh) 2013-05-28 2018-04-21 科麥農股份有限公司 4,6-雙(芳氧基)嘧啶衍生物的製備方法
AR100015A1 (es) 2013-07-08 2016-09-07 Arysta Lifescience Corp Procedimiento para preparar fluoxastrobin
ES2960228T3 (es) 2015-05-29 2024-03-01 Arysta Lifescience Corp Proceso de preparación de (E)-(5,6-dihidro-1,4,2-dioxazin-3-il)(2-hidroxifenil)metanona O-metil oxima
CN107428704A (zh) 2015-10-06 2017-12-01 Gsp作物科学有限公司 制备嘧菌酯的方法
CN105536873B (zh) * 2016-02-05 2017-11-28 帕潘纳(北京)科技有限公司 一种复合催化剂及其应用
CN110294716B (zh) 2018-03-23 2021-05-07 帕潘纳(北京)科技有限公司 一种嘧菌酯及其中间体的制备方法
TWI705961B (zh) * 2018-11-28 2020-10-01 興農股份有限公司 亞托敏的製備方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69114743T2 (de) * 1990-03-19 1996-05-30 Rohm & Haas Verfahren zur Herstellung von Fluormethyl-substituierten Dihydropyridin-carbodithioaten.
IL106324A (en) 1992-07-17 1998-09-24 Shell Int Research Transformed pyrimidine compounds, their preparation and use as pesticides
ZW8594A1 (en) 1993-08-11 1994-10-12 Bayer Ag Substituted azadioxacycbalkenes
DE4327596A1 (de) 1993-08-17 1995-02-23 Bayer Ag 3-Methoxy-2-phenyl-acrylsäuremethylester
GB9404375D0 (en) 1994-03-07 1994-04-20 Zeneca Ltd Fungicides
DE19531299A1 (de) 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen
CN1070189C (zh) 1995-10-18 2001-08-29 拜尔公司 氟代甲氧基丙烯酸衍生物
DE19602095A1 (de) * 1996-01-22 1997-07-24 Bayer Ag Halogenpyrimidine
UA53611C2 (uk) 1996-03-07 2003-02-17 Амерікан Ціанамід Компані Спосіб одержання несиметричних 4,6-біс(арилокси)піримідинових сполук
US5977363A (en) 1996-03-07 1999-11-02 American Cyanamid Company Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds
DE19642533A1 (de) 1996-10-15 1998-04-16 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin
DE19646407A1 (de) 1996-11-11 1998-05-14 Bayer Ag Halogenpyrimidine
WO1998023155A1 (en) 1996-11-26 1998-06-04 E.I. Du Pont De Nemours And Company Arthropodicidal and fungicidal cyclic amides
DE19710609A1 (de) 1997-03-14 1998-09-17 Bayer Ag Substituierte Aminosalicylsäureamide
DE19723195A1 (de) 1997-06-03 1998-12-10 Bayer Ag Fluormethoximinoverbindungen
US6251899B1 (en) 1997-08-14 2001-06-26 Bayer Aktiengesellschaft Methoximinomethyloxadiazines
US5849910A (en) * 1997-09-05 1998-12-15 American Cyanamid Company Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds
DE19819828A1 (de) 1998-05-04 1999-11-11 Bayer Ag Methoximinomethyloxathiazine

Also Published As

Publication number Publication date
CN1280278C (zh) 2006-10-18
IL151678A0 (en) 2003-04-10
EP1268446B1 (de) 2010-10-06
ES2353271T3 (es) 2011-02-28
US6734304B2 (en) 2004-05-11
MXPA02009286A (es) 2003-05-23
BR0109442B1 (pt) 2013-02-19
HUP0300267A2 (hu) 2003-06-28
US20030092723A1 (en) 2003-05-15
WO2001072719A1 (de) 2001-10-04
AU2001242454A1 (en) 2001-10-08
CN1419549A (zh) 2003-05-21
KR20030011779A (ko) 2003-02-11
JP2003528862A (ja) 2003-09-30
ATE483691T1 (de) 2010-10-15
IL151678A (en) 2005-08-31
KR100758615B1 (ko) 2007-09-13
HUP0300267A3 (en) 2005-11-28
TWI296621B (en) 2008-05-11
EP1268446A1 (de) 2003-01-02
JP5008242B2 (ja) 2012-08-22
AR034693A1 (es) 2004-03-17
DE50115655D1 (de) 2010-11-18
DE10014607A1 (de) 2001-09-27
DK1268446T3 (da) 2011-01-31

Similar Documents

Publication Publication Date Title
BR0109442A (pt) Processo para a preparação de derivados de 4,6-bis(arilóxi) pirimidina assimétricos
BR0211404A (pt) Aminas, ácidos, aminoácidos e tioéter ácidos substituìdos com perfluoroalquil
FI903331A0 (fi) Substituerade kinazolinoner, vilka aer anvaendbara som angiotensin-ii-antagonister.
BR9814300A (pt) Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos
BR0008056A (pt) Pirrolocarbazóis e isoindolonas cìclicas fundidas substituìdas
FI961196A (fi) Aktiviinin reseptoreita muistuttava kinaasi(alk), joka kuuluu TGF-reseptoriperheeseen ja/tai BMP-reseptoriperheeseen
EP1390490A4 (en) MUSCLE-SPECIFIC EXPRESSION VECTORS
DK0539086T3 (da) Kondenserede pyrimidinderivater og deres anvendelse som angiotensin II-antagonister
PT1083903E (pt) Indenopirrolocarbazoles em ponte
BR0209149A (pt) Ftalazinonas
DK0929547T3 (da) Benzamidinderivater substitueret af cykliske aminosyrederivater eller cykliske hydroxysyrederivater og deres anvendelse som antikoagulantia
TR200201270T2 (tr) Epinastin içeren çözeltiler.
TR199900486T2 (xx) Aziniloksi ve fenoksi-diaril-karbonasit t�revleri.
BR0014199A (pt) Derivados de bifenila como inibidores de nhe-3
DE68911197D1 (de) Kondensierte Pyrimidine, ihre Herstellung und Verwendung.
BR0213990A (pt) Derivados de piperazina tendo atividade antagonìstica de sst1
BRPI0410758A (pt) composições, dispositivos e métodos para estabilizar o dióxido de halogênio e aumentar sua eficácia
YU3802A (sh) Tableta za sisanje, koja sadrži ambroksol
BR0012736A (pt) Processo para a preparação de pirimidinas substituìdas, e, composto
DE10108995A1 (de) Substituierte Pyrimidinon-Derivate als Liganden von Integrinrezeptoren
DK0608693T3 (da) Fremgangsmåde til fremstilling af folinsyre
MXPA03008248A (es) Agentes colorantes para fibras de queratina que contienen derivados de n-heteroarilmetil-m-fenilendiamina, asi como nuevos derivados de n-heteroarilmetil-m-fenilendiamina.
DE60142330D1 (de) Verwendung von gamma-tocotrienol als diuretika
ES2188273T3 (es) Farmacos anticarcinogenos a base de antraquinona.
ATE410164T1 (de) Wässrige flüssige preparation von pranoprofen

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/02/2013, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved
B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 19/02/2023