BR0001602A - Composto de aminotriazol, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos - Google Patents
Composto de aminotriazol, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmosInfo
- Publication number
- BR0001602A BR0001602A BR0001602-0A BR0001602A BR0001602A BR 0001602 A BR0001602 A BR 0001602A BR 0001602 A BR0001602 A BR 0001602A BR 0001602 A BR0001602 A BR 0001602A
- Authority
- BR
- Brazil
- Prior art keywords
- heteroarylalkyl
- group
- optionally substituted
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- -1 Aminotriazole compound Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000001072 heteroaryl group Chemical group 0.000 abstract 3
- 125000004447 heteroarylalkenyl group Chemical group 0.000 abstract 2
- 125000005312 heteroarylalkynyl group Chemical group 0.000 abstract 2
- QOJFGOPBBIUODB-UHFFFAOYSA-N 3h-1,2,4-triazol-3-amine Chemical class NC1N=CN=N1 QOJFGOPBBIUODB-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005015 aryl alkynyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004957 naphthylene group Chemical group 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Patente de Invenção: <B>"COMPOSTOS DE AMINOTRIAZOL, PROCESSO PARA A PREPARAçãO DOS MESMOS E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS"<D>. O composto da fórmula (I): em que: n é 0 ou 1, W representa -CO- ou S(O)~ q~ e q é 0, 1 ou 2, G representa um grupo G~ 1~, G~ 2~, G~ 3~ ou G~ 4~ como definidos na descrição, Z representa um grupo alquil, ou um grupo aril, heteroaril, arilalquil, arilalquenil, arilalquinil, heteroarilalquenil, heteroarilalquinil ou heteroarilalquil, cada um substituído opcionalmente, A representa um grupamento selecionado de -A~ 2~-, -A~ 1~<sym>A~ 2~-, -A~ 2~-A~ 1~- e -A~ 1~-A~ 2~-A~ 1~- em que A~ 1~ é um grupo alquileno e A~ 2~ representa um grupo fenileno, cicloalquileno, naftileno ou heteroarileno, cada um substituído opcionalmente, R representa um átomo de hidrogênio, um grupo alquil ou um grupo aril, heteroaril, arilalquil, arilalquenil, arilalquinil, heteroarilalquenil, heteroarilalquinil ou heteroarilalquil, cada um substituído opcionalmente, R~ 1~ representa um grupo alquil ou um grupo aril, heteroaril, arilalquil, arilalquenil, arilalquinil, heteroarilalquenil, heteroarilalquinil ou heteroarilalquil, cada um substituído opcionalmente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9904721A FR2792314B1 (fr) | 1999-04-15 | 1999-04-15 | Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0001602A true BR0001602A (pt) | 2001-08-21 |
Family
ID=9544433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0001602-0A BR0001602A (pt) | 1999-04-15 | 2000-04-13 | Composto de aminotriazol, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos |
Country Status (19)
Country | Link |
---|---|
US (2) | US6245916B1 (pt) |
EP (1) | EP1044970B1 (pt) |
JP (1) | JP2000309579A (pt) |
KR (1) | KR20010020732A (pt) |
CN (1) | CN1145616C (pt) |
AT (1) | ATE231133T1 (pt) |
BR (1) | BR0001602A (pt) |
CA (1) | CA2305940A1 (pt) |
DE (1) | DE60001190T2 (pt) |
DK (1) | DK1044970T3 (pt) |
EA (1) | EA003023B1 (pt) |
ES (1) | ES2190396T3 (pt) |
FR (1) | FR2792314B1 (pt) |
HU (1) | HUP0001562A3 (pt) |
NO (1) | NO20001964L (pt) |
NZ (1) | NZ504023A (pt) |
PL (1) | PL339690A1 (pt) |
SI (1) | SI1044970T1 (pt) |
ZA (1) | ZA200001908B (pt) |
Families Citing this family (60)
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MXPA02010231A (es) | 2001-11-27 | 2004-12-13 | Warner Lambert Co | Inhibidores aminotransferasa dependientes de aminoacidos de cadena ramificada y su uso en el tratamiento de las enfermedades neurodegenerativas. |
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US8394765B2 (en) | 2004-11-01 | 2013-03-12 | Amylin Pharmaceuticals Llc | Methods of treating obesity with two different anti-obesity agents |
BRPI0610580B8 (pt) | 2005-05-30 | 2021-05-25 | Banyu Pharma Co Ltd | composto derivado de piperidina |
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PT3004138T (pt) | 2013-06-05 | 2024-06-18 | Bausch Health Ireland Ltd | Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos |
CA2959208C (en) | 2014-08-29 | 2023-09-19 | Tes Pharma S.R.L. | Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase |
EP3526199B1 (en) | 2016-10-14 | 2022-04-13 | Tes Pharma S.r.l. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
CA3119509A1 (en) | 2018-11-20 | 2020-05-28 | Tes Pharma S.R.L | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxxylase |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4326465A1 (de) * | 1993-01-20 | 1995-02-09 | Thomae Gmbh Dr K | Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
WO1997036859A1 (en) * | 1996-03-29 | 1997-10-09 | G.D. Searle & Co. | Para-substituted phenylpropanoic acid derivatives as integrin antagonists |
US6180653B1 (en) * | 1996-12-16 | 2001-01-30 | Banyu Pharmaceutical Co., Ltd. | Aminopyrazole derivatives |
PE20000127A1 (es) * | 1997-12-22 | 2000-03-14 | Novartis Ag | Derivado de bencenosulfonamida |
-
1999
- 1999-04-15 FR FR9904721A patent/FR2792314B1/fr not_active Expired - Fee Related
-
2000
- 2000-04-12 KR KR1020000019224A patent/KR20010020732A/ko active IP Right Grant
- 2000-04-13 BR BR0001602-0A patent/BR0001602A/pt not_active IP Right Cessation
- 2000-04-14 NO NO20001964A patent/NO20001964L/no not_active Application Discontinuation
- 2000-04-14 CA CA002305940A patent/CA2305940A1/fr not_active Abandoned
- 2000-04-14 DE DE60001190T patent/DE60001190T2/de not_active Expired - Fee Related
- 2000-04-14 CN CNB001065793A patent/CN1145616C/zh not_active Expired - Fee Related
- 2000-04-14 ZA ZA200001908A patent/ZA200001908B/xx unknown
- 2000-04-14 JP JP2000113113A patent/JP2000309579A/ja active Pending
- 2000-04-14 PL PL00339690A patent/PL339690A1/xx not_active Application Discontinuation
- 2000-04-14 DK DK00401039T patent/DK1044970T3/da active
- 2000-04-14 AT AT00401039T patent/ATE231133T1/de not_active IP Right Cessation
- 2000-04-14 ES ES00401039T patent/ES2190396T3/es not_active Expired - Lifetime
- 2000-04-14 HU HU0001562A patent/HUP0001562A3/hu unknown
- 2000-04-14 EP EP00401039A patent/EP1044970B1/fr not_active Expired - Lifetime
- 2000-04-14 NZ NZ504023A patent/NZ504023A/xx unknown
- 2000-04-14 US US09/549,745 patent/US6245916B1/en not_active Expired - Fee Related
- 2000-04-14 EA EA200000327A patent/EA003023B1/ru not_active IP Right Cessation
- 2000-04-14 SI SI200030042T patent/SI1044970T1/xx unknown
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2001
- 2001-03-05 US US09/799,199 patent/US6596749B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2792314A1 (fr) | 2000-10-20 |
DE60001190D1 (de) | 2003-02-20 |
HUP0001562A2 (hu) | 2001-04-28 |
CN1145616C (zh) | 2004-04-14 |
ATE231133T1 (de) | 2003-02-15 |
NZ504023A (en) | 2000-10-27 |
DE60001190T2 (de) | 2003-10-09 |
NO20001964D0 (no) | 2000-04-14 |
JP2000309579A (ja) | 2000-11-07 |
US6596749B2 (en) | 2003-07-22 |
KR20010020732A (ko) | 2001-03-15 |
EA200000327A2 (ru) | 2000-10-30 |
EA003023B1 (ru) | 2002-12-26 |
CA2305940A1 (fr) | 2000-10-15 |
US20010018522A1 (en) | 2001-08-30 |
DK1044970T3 (da) | 2003-04-22 |
CN1272493A (zh) | 2000-11-08 |
HU0001562D0 (en) | 2000-06-28 |
HUP0001562A3 (en) | 2003-05-28 |
EP1044970A1 (fr) | 2000-10-18 |
PL339690A1 (en) | 2000-10-23 |
SI1044970T1 (en) | 2003-06-30 |
ZA200001908B (en) | 2000-10-31 |
EP1044970B1 (fr) | 2003-01-15 |
NO20001964L (no) | 2000-10-16 |
US6245916B1 (en) | 2001-06-12 |
ES2190396T3 (es) | 2003-08-01 |
FR2792314B1 (fr) | 2001-06-01 |
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