BR9815081A - Compostos tricìclicos, um processo para a sua preparação e composições farmacêuticas contendo-os - Google Patents
Compostos tricìclicos, um processo para a sua preparação e composições farmacêuticas contendo-osInfo
- Publication number
- BR9815081A BR9815081A BR9815081-2A BR9815081A BR9815081A BR 9815081 A BR9815081 A BR 9815081A BR 9815081 A BR9815081 A BR 9815081A BR 9815081 A BR9815081 A BR 9815081A
- Authority
- BR
- Brazil
- Prior art keywords
- sym
- preparation
- pharmaceutical compositions
- compositions containing
- tricyclic compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/20—Acenaphthenes; Hydrogenated acenaphthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/28—Phenalenes; Hydrogenated phenalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Patente de Invenção: <B>"COMPOSTOS TRICìCLICOS, UM PROCESSO PARA A SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO-OS"<D>. A invenção refere-se a compostos de fórmula (I): em que: <sym> A forma um sistema tricíclico de fórmula A~ 1~, A~ 2~, A~ 3~ e A~ 4~, <sym> R~ 1~ representa um átomo de hidrogênio ou um grupo alquila, hidróxi, alcóxi ou oxo, <sym> (R²)~ m~ e (R³)~ m'~ são como definidos no relatório descritivo, <sym> n representa um número inteiro tal que 0 <243> n <243> 3, <sym> p representa um número inteiro como definido no relatório descritivo, e <sym> B representa um grupo
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9800424A FR2773798B1 (fr) | 1998-01-16 | 1998-01-16 | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR1998/002694 WO1999036392A1 (fr) | 1998-01-16 | 1998-12-11 | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9815081A true BR9815081A (pt) | 2000-10-17 |
Family
ID=9521844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9815081-2A BR9815081A (pt) | 1998-01-16 | 1998-12-11 | Compostos tricìclicos, um processo para a sua preparação e composições farmacêuticas contendo-os |
Country Status (20)
Country | Link |
---|---|
US (1) | US6423870B1 (pt) |
EP (1) | EP1047664B1 (pt) |
JP (1) | JP2002509130A (pt) |
CN (1) | CN1247528C (pt) |
AT (1) | ATE267163T1 (pt) |
AU (1) | AU739488B2 (pt) |
BR (1) | BR9815081A (pt) |
CA (1) | CA2318381C (pt) |
DE (1) | DE69824046T2 (pt) |
DK (1) | DK1047664T3 (pt) |
ES (1) | ES2221999T3 (pt) |
FR (1) | FR2773798B1 (pt) |
HK (1) | HK1033455A1 (pt) |
HU (1) | HUP0100283A3 (pt) |
NO (1) | NO20003604L (pt) |
NZ (1) | NZ505323A (pt) |
PL (1) | PL195664B1 (pt) |
PT (1) | PT1047664E (pt) |
WO (1) | WO1999036392A1 (pt) |
ZA (1) | ZA9811380B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6025355A (en) * | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
GB9726569D0 (en) * | 1997-12-16 | 1998-02-11 | Univ Southampton | Neuroprotective agents |
DE10133927A1 (de) * | 2001-07-12 | 2003-01-23 | Bayer Ag | Benzodioxinothiophene, deren Herstellung und Verwendung |
US6930190B2 (en) * | 2001-08-01 | 2005-08-16 | Basell Polyolefine Gmbh | Process for the preparation of heterocyclic pentalene derivatives |
MX2009007058A (es) * | 2006-12-28 | 2009-07-10 | Takeda Pharmaceutical | Compuesto triciclico y uso farmaceutico del mismo. |
FR2934857B1 (fr) * | 2008-08-05 | 2010-08-27 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
TW202220965A (zh) * | 2020-08-06 | 2022-06-01 | 美商塔朵根公司 | 用於心理疾患或心理增強之2-胺基茚滿化合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9407919D0 (en) * | 1994-04-21 | 1994-06-15 | Glaxo Group Ltd | Chemical compounds |
DE69517433T2 (de) | 1994-09-12 | 2001-02-08 | Takeda Chemical Industries Ltd | Benzozykloalkenverbindungen, deren herstellung und verwendung |
FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2732964B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
FR2734815B1 (fr) * | 1995-05-31 | 1997-07-04 | Adir | Nouveaux composes arylalkyl (thio) carboxamides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
SK283970B6 (sk) * | 1996-03-08 | 2004-06-08 | Takeda Chemical Industries, Ltd. | Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci |
-
1998
- 1998-01-16 FR FR9800424A patent/FR2773798B1/fr not_active Expired - Fee Related
- 1998-12-11 WO PCT/FR1998/002694 patent/WO1999036392A1/fr active IP Right Grant
- 1998-12-11 HU HU0100283A patent/HUP0100283A3/hu unknown
- 1998-12-11 JP JP2000540110A patent/JP2002509130A/ja active Pending
- 1998-12-11 ES ES98959957T patent/ES2221999T3/es not_active Expired - Lifetime
- 1998-12-11 CA CA002318381A patent/CA2318381C/fr not_active Expired - Fee Related
- 1998-12-11 BR BR9815081-2A patent/BR9815081A/pt not_active Application Discontinuation
- 1998-12-11 AU AU15676/99A patent/AU739488B2/en not_active Ceased
- 1998-12-11 PL PL98341837A patent/PL195664B1/pl not_active IP Right Cessation
- 1998-12-11 CN CNB988131374A patent/CN1247528C/zh not_active Expired - Fee Related
- 1998-12-11 US US09/600,373 patent/US6423870B1/en not_active Expired - Fee Related
- 1998-12-11 NZ NZ505323A patent/NZ505323A/xx unknown
- 1998-12-11 ZA ZA9811380A patent/ZA9811380B/xx unknown
- 1998-12-11 EP EP98959957A patent/EP1047664B1/fr not_active Expired - Lifetime
- 1998-12-11 PT PT98959957T patent/PT1047664E/pt unknown
- 1998-12-11 DK DK98959957T patent/DK1047664T3/da active
- 1998-12-11 AT AT98959957T patent/ATE267163T1/de not_active IP Right Cessation
- 1998-12-11 DE DE69824046T patent/DE69824046T2/de not_active Expired - Fee Related
-
2000
- 2000-07-13 NO NO20003604A patent/NO20003604L/no not_active Application Discontinuation
-
2001
- 2001-06-18 HK HK01104169A patent/HK1033455A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ505323A (en) | 2002-10-25 |
AU1567699A (en) | 1999-08-02 |
HUP0100283A3 (en) | 2002-05-28 |
ZA9811380B (pt) | 1999-06-14 |
PL341837A1 (en) | 2001-05-07 |
CN1285817A (zh) | 2001-02-28 |
JP2002509130A (ja) | 2002-03-26 |
DE69824046D1 (de) | 2004-06-24 |
WO1999036392A1 (fr) | 1999-07-22 |
DK1047664T3 (da) | 2004-09-13 |
ES2221999T3 (es) | 2005-01-16 |
NO20003604D0 (no) | 2000-07-13 |
CN1247528C (zh) | 2006-03-29 |
EP1047664B1 (fr) | 2004-05-19 |
CA2318381A1 (fr) | 1999-07-22 |
EP1047664A1 (fr) | 2000-11-02 |
PT1047664E (pt) | 2004-08-31 |
DE69824046T2 (de) | 2005-06-30 |
US6423870B1 (en) | 2002-07-23 |
FR2773798B1 (fr) | 2001-02-02 |
HK1033455A1 (en) | 2001-08-31 |
HUP0100283A2 (hu) | 2002-04-29 |
NO20003604L (no) | 2000-09-12 |
FR2773798A1 (fr) | 1999-07-23 |
AU739488B2 (en) | 2001-10-11 |
ATE267163T1 (de) | 2004-06-15 |
PL195664B1 (pl) | 2007-10-31 |
CA2318381C (fr) | 2007-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer |
Free format text: LES LABORATOIRES SERVIER (FR) |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |