AU739488B2 - New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents
New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- AU739488B2 AU739488B2 AU15676/99A AU1567699A AU739488B2 AU 739488 B2 AU739488 B2 AU 739488B2 AU 15676/99 A AU15676/99 A AU 15676/99A AU 1567699 A AU1567699 A AU 1567699A AU 739488 B2 AU739488 B2 AU 739488B2
- Authority
- AU
- Australia
- Prior art keywords
- formula
- group
- compounds
- compound
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/20—Acenaphthenes; Hydrogenated acenaphthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/28—Phenalenes; Hydrogenated phenalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR98/00424 | 1998-01-16 | ||
FR9800424A FR2773798B1 (fr) | 1998-01-16 | 1998-01-16 | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR1998/002694 WO1999036392A1 (fr) | 1998-01-16 | 1998-12-11 | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
AU1567699A AU1567699A (en) | 1999-08-02 |
AU739488B2 true AU739488B2 (en) | 2001-10-11 |
Family
ID=9521844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU15676/99A Ceased AU739488B2 (en) | 1998-01-16 | 1998-12-11 | New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them |
Country Status (20)
Country | Link |
---|---|
US (1) | US6423870B1 (pt) |
EP (1) | EP1047664B1 (pt) |
JP (1) | JP2002509130A (pt) |
CN (1) | CN1247528C (pt) |
AT (1) | ATE267163T1 (pt) |
AU (1) | AU739488B2 (pt) |
BR (1) | BR9815081A (pt) |
CA (1) | CA2318381C (pt) |
DE (1) | DE69824046T2 (pt) |
DK (1) | DK1047664T3 (pt) |
ES (1) | ES2221999T3 (pt) |
FR (1) | FR2773798B1 (pt) |
HK (1) | HK1033455A1 (pt) |
HU (1) | HUP0100283A3 (pt) |
NO (1) | NO20003604L (pt) |
NZ (1) | NZ505323A (pt) |
PL (1) | PL195664B1 (pt) |
PT (1) | PT1047664E (pt) |
WO (1) | WO1999036392A1 (pt) |
ZA (1) | ZA9811380B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6025355A (en) * | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
GB9726569D0 (en) * | 1997-12-16 | 1998-02-11 | Univ Southampton | Neuroprotective agents |
DE10133927A1 (de) * | 2001-07-12 | 2003-01-23 | Bayer Ag | Benzodioxinothiophene, deren Herstellung und Verwendung |
EP1412347B1 (en) * | 2001-08-01 | 2006-01-11 | Basell Polyolefine GmbH | Process for the preparation of heterocyclic pentalene derivatives |
US8247429B2 (en) * | 2006-12-28 | 2012-08-21 | Takeda Pharmaceutical Company Limited | Tricyclic compound and pharmaceutical use thereof |
FR2934857B1 (fr) * | 2008-08-05 | 2010-08-27 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
TW202220965A (zh) * | 2020-08-06 | 2022-06-01 | 美商塔朵根公司 | 用於心理疾患或心理增強之2-胺基茚滿化合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9407919D0 (en) * | 1994-04-21 | 1994-06-15 | Glaxo Group Ltd | Chemical compounds |
WO1996008466A1 (en) | 1994-09-12 | 1996-03-21 | Takeda Chemical Industries, Ltd. | Benzocycloalkene compounds, their production and use |
FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2732964B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
FR2734815B1 (fr) * | 1995-05-31 | 1997-07-04 | Adir | Nouveaux composes arylalkyl (thio) carboxamides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
HU224220B1 (hu) * | 1996-03-08 | 2005-06-28 | Takeda Pharmaceutical Company Limited | Triciklusos vegyületek, eljárás előállításukra és alkalmazásuk |
-
1998
- 1998-01-16 FR FR9800424A patent/FR2773798B1/fr not_active Expired - Fee Related
- 1998-12-11 EP EP98959957A patent/EP1047664B1/fr not_active Expired - Lifetime
- 1998-12-11 CN CNB988131374A patent/CN1247528C/zh not_active Expired - Fee Related
- 1998-12-11 DE DE69824046T patent/DE69824046T2/de not_active Expired - Fee Related
- 1998-12-11 US US09/600,373 patent/US6423870B1/en not_active Expired - Fee Related
- 1998-12-11 PL PL98341837A patent/PL195664B1/pl not_active IP Right Cessation
- 1998-12-11 CA CA002318381A patent/CA2318381C/fr not_active Expired - Fee Related
- 1998-12-11 JP JP2000540110A patent/JP2002509130A/ja active Pending
- 1998-12-11 AU AU15676/99A patent/AU739488B2/en not_active Ceased
- 1998-12-11 ES ES98959957T patent/ES2221999T3/es not_active Expired - Lifetime
- 1998-12-11 AT AT98959957T patent/ATE267163T1/de not_active IP Right Cessation
- 1998-12-11 PT PT98959957T patent/PT1047664E/pt unknown
- 1998-12-11 NZ NZ505323A patent/NZ505323A/xx unknown
- 1998-12-11 ZA ZA9811380A patent/ZA9811380B/xx unknown
- 1998-12-11 HU HU0100283A patent/HUP0100283A3/hu unknown
- 1998-12-11 WO PCT/FR1998/002694 patent/WO1999036392A1/fr active IP Right Grant
- 1998-12-11 DK DK98959957T patent/DK1047664T3/da active
- 1998-12-11 BR BR9815081-2A patent/BR9815081A/pt not_active Application Discontinuation
-
2000
- 2000-07-13 NO NO20003604A patent/NO20003604L/no not_active Application Discontinuation
-
2001
- 2001-06-18 HK HK01104169A patent/HK1033455A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUP0100283A2 (hu) | 2002-04-29 |
DE69824046T2 (de) | 2005-06-30 |
ES2221999T3 (es) | 2005-01-16 |
HUP0100283A3 (en) | 2002-05-28 |
PT1047664E (pt) | 2004-08-31 |
CN1285817A (zh) | 2001-02-28 |
WO1999036392A1 (fr) | 1999-07-22 |
FR2773798A1 (fr) | 1999-07-23 |
DK1047664T3 (da) | 2004-09-13 |
PL195664B1 (pl) | 2007-10-31 |
JP2002509130A (ja) | 2002-03-26 |
NZ505323A (en) | 2002-10-25 |
BR9815081A (pt) | 2000-10-17 |
ATE267163T1 (de) | 2004-06-15 |
CA2318381C (fr) | 2007-04-17 |
FR2773798B1 (fr) | 2001-02-02 |
HK1033455A1 (en) | 2001-08-31 |
AU1567699A (en) | 1999-08-02 |
EP1047664B1 (fr) | 2004-05-19 |
CA2318381A1 (fr) | 1999-07-22 |
US6423870B1 (en) | 2002-07-23 |
NO20003604D0 (no) | 2000-07-13 |
NO20003604L (no) | 2000-09-12 |
EP1047664A1 (fr) | 2000-11-02 |
DE69824046D1 (de) | 2004-06-24 |
PL341837A1 (en) | 2001-05-07 |
ZA9811380B (pt) | 1999-06-14 |
CN1247528C (zh) | 2006-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1 | Assignment before grant (sect. 113) |
Owner name: LES LABORATOIRES SERVIER Free format text: THE FORMER OWNER WAS: ADIR ET COMPAGNIE |
|
FGA | Letters patent sealed or granted (standard patent) |