BG98194A - Фибриногенни рецепторни антагонисти - Google Patents
Фибриногенни рецепторни антагонисти Download PDFInfo
- Publication number
- BG98194A BG98194A BG98194A BG9819493A BG98194A BG 98194 A BG98194 A BG 98194A BG 98194 A BG98194 A BG 98194A BG 9819493 A BG9819493 A BG 9819493A BG 98194 A BG98194 A BG 98194A
- Authority
- BG
- Bulgaria
- Prior art keywords
- agent
- mammal
- pharmaceutically acceptable
- administered
- inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69689391A | 1991-05-07 | 1991-05-07 | |
US72035791A | 1991-06-25 | 1991-06-25 | |
US87126292A | 1992-04-23 | 1992-04-23 | |
PCT/US1992/003463 WO1992019595A1 (fr) | 1991-05-07 | 1992-04-27 | Antagonistes de recepteur de fibrinogene |
Publications (1)
Publication Number | Publication Date |
---|---|
BG98194A true BG98194A (bg) | 1994-09-30 |
Family
ID=27418643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG98194A BG98194A (bg) | 1991-05-07 | 1993-11-02 | Фибриногенни рецепторни антагонисти |
Country Status (20)
Country | Link |
---|---|
US (2) | US5281585A (fr) |
EP (1) | EP0512831B1 (fr) |
JP (1) | JP2531562B2 (fr) |
KR (1) | KR920021531A (fr) |
CN (1) | CN1067883A (fr) |
AT (1) | ATE184874T1 (fr) |
AU (1) | AU647618B2 (fr) |
BG (1) | BG98194A (fr) |
CA (1) | CA2068064C (fr) |
DE (1) | DE69230013T2 (fr) |
ES (1) | ES2137175T3 (fr) |
FI (1) | FI934894A0 (fr) |
HU (1) | HUT68769A (fr) |
IE (1) | IE921463A1 (fr) |
IL (1) | IL101779A0 (fr) |
MX (1) | MXPA92002103A (fr) |
NO (1) | NO933999L (fr) |
NZ (1) | NZ242609A (fr) |
WO (1) | WO1992019595A1 (fr) |
YU (1) | YU47992A (fr) |
Families Citing this family (112)
Publication number | Priority date | Publication date | Assignee | Title |
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US5672585A (en) * | 1990-04-06 | 1997-09-30 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US6521594B1 (en) | 1990-04-06 | 2003-02-18 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US6017877A (en) * | 1990-04-06 | 2000-01-25 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
WO1993018058A1 (fr) * | 1992-03-06 | 1993-09-16 | G.D. Searle & Co. | Imitateurs peptidiques utiles comme inhibiteurs de l'agregation plaquettaire |
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DE4308034A1 (de) * | 1993-03-13 | 1994-09-15 | Cassella Ag | Neue Heterocyclen, ihre Herstellung und ihre Verwendung |
US5753659A (en) * | 1993-03-29 | 1998-05-19 | Zeneca Limited | Heterocyclic compouds |
US5652242A (en) * | 1993-03-29 | 1997-07-29 | Zeneca Limited | Heterocyclic derivatives |
GB9406143D0 (en) * | 1993-03-29 | 1994-05-18 | Zeneca Ltd | Heterocyclic derivatives |
CA2155307A1 (fr) * | 1993-03-29 | 1994-10-13 | Michael Garth Wayne | Composes heterocycliques, inhibiteurs de l'agregation des plaquettes |
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
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EP0725059B1 (fr) * | 1993-10-19 | 2001-01-17 | Sumitomo Pharmaceuticals Company, Limited | Derive d'acide 2,3-diaminopropionique |
DE4427979A1 (de) * | 1993-11-15 | 1996-02-15 | Cassella Ag | Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung |
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US5523302A (en) * | 1993-11-24 | 1996-06-04 | The Du Pont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
US5446056A (en) * | 1993-11-24 | 1995-08-29 | The Du Pont Merck Pharmaceutical Company | Isoxazoline compounds useful as fibrinogen receptor antagonists |
US5563158A (en) * | 1993-12-28 | 1996-10-08 | The Dupont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
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US5064814A (en) * | 1990-04-05 | 1991-11-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Anti-thrombotic peptide and pseudopeptide derivatives |
IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical preparations containing them |
NZ239876A (en) * | 1990-09-27 | 1993-12-23 | Merck & Co Inc | Glycyl-b-alanine derivatives and pharmaceutical compositions thereof. |
-
1992
- 1992-04-27 HU HU9303145A patent/HUT68769A/hu unknown
- 1992-04-27 WO PCT/US1992/003463 patent/WO1992019595A1/fr not_active Application Discontinuation
- 1992-05-05 IL IL101779A patent/IL101779A0/xx unknown
- 1992-05-05 NZ NZ242609A patent/NZ242609A/en unknown
- 1992-05-06 YU YU47992A patent/YU47992A/sh unknown
- 1992-05-06 CA CA002068064A patent/CA2068064C/fr not_active Expired - Fee Related
- 1992-05-06 CN CN92104545A patent/CN1067883A/zh active Pending
- 1992-05-06 MX MXPA92002103A patent/MXPA92002103A/es unknown
- 1992-05-07 AU AU16111/92A patent/AU647618B2/en not_active Ceased
- 1992-05-07 JP JP4158496A patent/JP2531562B2/ja not_active Expired - Lifetime
- 1992-05-07 KR KR1019920007683A patent/KR920021531A/ko not_active Application Discontinuation
- 1992-05-07 DE DE69230013T patent/DE69230013T2/de not_active Expired - Fee Related
- 1992-05-07 AT AT92304113T patent/ATE184874T1/de active
- 1992-05-07 EP EP92304113A patent/EP0512831B1/fr not_active Expired - Lifetime
- 1992-05-07 ES ES92304113T patent/ES2137175T3/es not_active Expired - Lifetime
- 1992-07-01 IE IE146392A patent/IE921463A1/en not_active Application Discontinuation
- 1992-11-06 US US07/972,668 patent/US5281585A/en not_active Expired - Fee Related
-
1993
- 1993-11-02 BG BG98194A patent/BG98194A/bg unknown
- 1993-11-05 NO NO933999A patent/NO933999L/no unknown
- 1993-11-05 FI FI934894A patent/FI934894A0/fi unknown
- 1993-12-20 US US08/169,947 patent/US5455243A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69230013T2 (de) | 2000-04-27 |
HUT68769A (en) | 1995-07-28 |
US5455243A (en) | 1995-10-03 |
EP0512831B1 (fr) | 1999-09-22 |
US5281585A (en) | 1994-01-25 |
MXPA92002103A (es) | 2005-08-25 |
JPH069525A (ja) | 1994-01-18 |
CA2068064C (fr) | 2001-01-02 |
YU47992A (sh) | 1995-03-27 |
NO933999D0 (no) | 1993-11-05 |
CN1067883A (zh) | 1993-01-13 |
FI934894A (fi) | 1993-11-05 |
FI934894A0 (fi) | 1993-11-05 |
AU647618B2 (en) | 1994-03-24 |
ATE184874T1 (de) | 1999-10-15 |
DE69230013D1 (de) | 1999-10-28 |
AU1611192A (en) | 1992-11-12 |
HU9303145D0 (en) | 1994-01-28 |
IE921463A1 (en) | 1992-11-18 |
EP0512831A1 (fr) | 1992-11-11 |
NZ242609A (en) | 1995-04-27 |
JP2531562B2 (ja) | 1996-09-04 |
ES2137175T3 (es) | 1999-12-16 |
WO1992019595A1 (fr) | 1992-11-12 |
CA2068064A1 (fr) | 1992-11-08 |
NO933999L (no) | 1993-11-05 |
IL101779A0 (en) | 1992-12-30 |
KR920021531A (ko) | 1992-12-18 |
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