BG64707B1 - 2-хало-6-о-заместени кетолидни производни - Google Patents

2-хало-6-о-заместени кетолидни производни Download PDF

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Publication number
BG64707B1
BG64707B1 BG104434A BG10443400A BG64707B1 BG 64707 B1 BG64707 B1 BG 64707B1 BG 104434 A BG104434 A BG 104434A BG 10443400 A BG10443400 A BG 10443400A BG 64707 B1 BG64707 B1 BG 64707B1
Authority
BG
Bulgaria
Prior art keywords
compound
formula
quinolinyl
xef
hydrogen
Prior art date
Application number
BG104434A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG104434A (en
Inventor
Ly Phan
Yat Sun Or
Daniel Chu
Jacob Plattner
Yan Chen
Richard Clark
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG104434A publication Critical patent/BG104434A/xx
Publication of BG64707B1 publication Critical patent/BG64707B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
BG104434A 1997-10-29 2000-05-15 2-хало-6-о-заместени кетолидни производни BG64707B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95988197A 1997-10-29 1997-10-29
US15423998A 1998-09-16 1998-09-16

Publications (2)

Publication Number Publication Date
BG104434A BG104434A (en) 2001-01-31
BG64707B1 true BG64707B1 (bg) 2005-12-30

Family

ID=26851273

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104434A BG64707B1 (bg) 1997-10-29 2000-05-15 2-хало-6-о-заместени кетолидни производни

Country Status (25)

Country Link
EP (1) EP1027362B1 (da)
JP (1) JP2001521039A (da)
KR (1) KR100536420B1 (da)
CN (1) CN1240707C (da)
AR (1) AR015994A1 (da)
AT (1) ATE298760T1 (da)
AU (1) AU751448B2 (da)
BG (1) BG64707B1 (da)
BR (1) BR9813319A (da)
CA (1) CA2307788C (da)
CO (1) CO4990960A1 (da)
CZ (1) CZ300063B6 (da)
DE (1) DE69830739T2 (da)
DK (1) DK1027362T3 (da)
ES (1) ES2244094T3 (da)
HK (1) HK1031383A1 (da)
HU (1) HUP0004282A3 (da)
IL (1) IL135519A0 (da)
NO (1) NO20002190L (da)
NZ (1) NZ503822A (da)
PL (1) PL191453B1 (da)
PT (1) PT1027362E (da)
SK (1) SK286397B6 (da)
TR (1) TR200001142T2 (da)
WO (1) WO1999021871A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39743E1 (en) * 1998-10-15 2007-07-24 Aventis Pharma S.A. 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use
FR2784682B1 (fr) * 1998-10-15 2002-12-06 Hoechst Marion Roussel Inc Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
CN1241931C (zh) * 1999-04-16 2006-02-15 高山生物科学股份有限公司 大环内酯抗感染药物
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
JP2003527347A (ja) * 1999-12-02 2003-09-16 アボット・ラボラトリーズ ６−ｏ−アルキル−２−ノル−２−置換ケトリド誘導体
US6569836B2 (en) 1999-12-02 2003-05-27 Abbott Laboratories 6-O-alkyl-2-nor-2-substituted ketolide derivatives
JP2001261694A (ja) * 2000-03-06 2001-09-26 Pfizer Prod Inc ケトライド抗生物質
US6605707B1 (en) 2000-03-23 2003-08-12 Abbott Laboratories Process for the preparation of 6-O-propargyl erythromycin derivatives
ATE271062T1 (de) 2000-06-30 2004-07-15 Pfizer Prod Inc Makrolid-antibiotika
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
EP1430068A1 (en) 2001-09-17 2004-06-23 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
BR0214748A (pt) 2001-12-05 2004-11-23 Ortho Mcneil Pharm Inc Derivados 6-oacil-cetolidas de eritromicina, úteis como antibacterianos
WO2003068790A2 (en) * 2002-02-13 2003-08-21 Abbott Laboratories Macrolide antibacterial compounds
MXPA04010556A (es) * 2002-04-25 2005-02-17 Abbott Lab Antibacterianos oxalida.
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
JPWO2004078771A1 (ja) * 2003-03-07 2006-06-08 大正製薬株式会社 ２−フルオロ−６−ｏ−置換ケトライド誘導体
JP2007254285A (ja) * 2004-03-16 2007-10-04 Taisho Pharmaceut Co Ltd ２−フルオロ−６−ｏ−置換ケトライド誘導体
NZ596628A (en) * 2009-05-27 2013-03-28 Ketolide compounds having antimicrobial activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
AU662420B2 (en) * 1992-04-22 1995-08-31 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide A derivative
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
NO20002190L (no) 2000-06-29
DE69830739D1 (de) 2005-08-04
ES2244094T3 (es) 2005-12-01
CN1240707C (zh) 2006-02-08
BR9813319A (pt) 2000-08-22
CO4990960A1 (es) 2000-12-26
IL135519A0 (en) 2001-05-20
CZ20001525A3 (cs) 2000-10-11
HK1031383A1 (en) 2001-06-15
AR015994A1 (es) 2001-05-30
SK286397B6 (sk) 2008-09-05
PT1027362E (pt) 2005-08-31
PL340290A1 (en) 2001-01-29
CA2307788A1 (en) 1999-05-06
DK1027362T3 (da) 2005-10-31
EP1027362B1 (en) 2005-06-29
SK6332000A3 (en) 2000-09-12
HUP0004282A2 (hu) 2001-04-28
WO1999021871A1 (en) 1999-05-06
CZ300063B6 (cs) 2009-01-21
TR200001142T2 (tr) 2000-09-21
JP2001521039A (ja) 2001-11-06
CN1283199A (zh) 2001-02-07
AU1288199A (en) 1999-05-17
KR100536420B1 (ko) 2005-12-16
ATE298760T1 (de) 2005-07-15
DE69830739T2 (de) 2006-04-20
BG104434A (en) 2001-01-31
CA2307788C (en) 2008-05-20
KR20010015793A (ko) 2001-02-26
EP1027362A1 (en) 2000-08-16
HUP0004282A3 (en) 2001-10-29
NO20002190D0 (no) 2000-04-27
NZ503822A (en) 2002-12-20
PL191453B1 (pl) 2006-05-31
AU751448B2 (en) 2002-08-15

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