BG64669B1 - Хидрофилни бинарни системи за приемане на циклоспорин - Google Patents

Хидрофилни бинарни системи за приемане на циклоспорин Download PDF

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Publication number
BG64669B1
BG64669B1 BG103790A BG10379099A BG64669B1 BG 64669 B1 BG64669 B1 BG 64669B1 BG 103790 A BG103790 A BG 103790A BG 10379099 A BG10379099 A BG 10379099A BG 64669 B1 BG64669 B1 BG 64669B1
Authority
BG
Bulgaria
Prior art keywords
weight
cyclosporine
composition according
propylene glycol
binary
Prior art date
Application number
BG103790A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103790A (en
Inventor
Laman Al-Razzak
Panayiotis Constantinides
Dilip Kaul
John Lipari
Lisa Mcchesney-Harris
Bashar Abdullah
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG103790A publication Critical patent/BG103790A/xx
Publication of BG64669B1 publication Critical patent/BG64669B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BG103790A 1997-03-12 1999-10-08 Хидрофилни бинарни системи за приемане на циклоспорин BG64669B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81637597A 1997-03-12 1997-03-12

Publications (2)

Publication Number Publication Date
BG103790A BG103790A (en) 2000-07-31
BG64669B1 true BG64669B1 (bg) 2005-11-30

Family

ID=25220436

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103790A BG64669B1 (bg) 1997-03-12 1999-10-08 Хидрофилни бинарни системи за приемане на циклоспорин

Country Status (25)

Country Link
US (1) US6008192A (ko)
EP (1) EP0969856B1 (ko)
JP (2) JP4718653B2 (ko)
KR (1) KR100966245B1 (ko)
CN (1) CN1309414C (ko)
AT (1) ATE286403T1 (ko)
AU (1) AU6461898A (ko)
BG (1) BG64669B1 (ko)
BR (1) BR9808656A (ko)
CA (1) CA2284000C (ko)
CZ (1) CZ301382B6 (ko)
DE (1) DE69828496T2 (ko)
DK (1) DK0969856T3 (ko)
ES (1) ES2236891T3 (ko)
HK (1) HK1026840A1 (ko)
HU (1) HU228855B1 (ko)
IL (2) IL131609A0 (ko)
NO (1) NO994266L (ko)
NZ (1) NZ337316A (ko)
PL (1) PL193414B1 (ko)
PT (1) PT969856E (ko)
SI (1) SI0969856T1 (ko)
SK (1) SK282714B6 (ko)
TR (1) TR199902199T2 (ko)
WO (1) WO1998040094A1 (ko)

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IT1294205B1 (it) * 1997-07-23 1999-03-24 Farmigea Spa Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
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DE19859910C2 (de) * 1998-12-23 2001-03-22 Ratiopharm Gmbh Orales Arzneimittel
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US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
WO1994023733A1 (de) * 1993-04-20 1994-10-27 Dr. Rentschler Arzneimittel Gmbh & Co. Neue pharmazeutische zubereitungen zur oralen verabreichung enthaltend cyclosporin

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Patent Citations (4)

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US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
WO1992009299A1 (en) * 1990-11-27 1992-06-11 BIOGAL Gyógyszergyár Rt. Oral pharmaceutical composition containing cyclosporin and process for preparing same
WO1994023733A1 (de) * 1993-04-20 1994-10-27 Dr. Rentschler Arzneimittel Gmbh & Co. Neue pharmazeutische zubereitungen zur oralen verabreichung enthaltend cyclosporin

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Publication number Publication date
BR9808656A (pt) 2000-05-23
CA2284000C (en) 2012-01-03
PL335575A1 (en) 2000-05-08
EP0969856B1 (en) 2005-01-05
ES2236891T3 (es) 2005-07-16
CZ301382B6 (cs) 2010-02-10
CN1309414C (zh) 2007-04-11
IL131609A0 (en) 2001-01-28
WO1998040094A1 (en) 1998-09-17
NO994266D0 (no) 1999-09-02
EP0969856A1 (en) 2000-01-12
BG103790A (en) 2000-07-31
DE69828496D1 (de) 2005-02-10
IL131609A (en) 2012-04-30
ATE286403T1 (de) 2005-01-15
JP2001516351A (ja) 2001-09-25
TR199902199T2 (xx) 2002-06-21
AU6461898A (en) 1998-09-29
SI0969856T1 (en) 2005-06-30
HUP0001782A3 (en) 2001-04-28
NO994266L (no) 1999-11-10
PT969856E (pt) 2005-04-29
SK119999A3 (en) 2000-02-14
CZ312999A3 (cs) 2000-01-12
US6008192A (en) 1999-12-28
HU228855B1 (en) 2013-06-28
DK0969856T3 (da) 2005-05-02
KR100966245B1 (ko) 2010-06-28
DE69828496T2 (de) 2006-03-23
HK1026840A1 (en) 2000-12-29
NZ337316A (en) 2001-06-29
PL193414B1 (pl) 2007-02-28
JP2011105754A (ja) 2011-06-02
CA2284000A1 (en) 1998-09-17
JP4718653B2 (ja) 2011-07-06
CN1250377A (zh) 2000-04-12
SK282714B6 (sk) 2002-11-06
KR20000076443A (ko) 2000-12-26
HUP0001782A2 (hu) 2000-12-28

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