BG64525B1 - Използване инхибиторите на карбоанхидразата за лечение на оток на макулата - Google Patents

Използване инхибиторите на карбоанхидразата за лечение на оток на макулата Download PDF

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Publication number
BG64525B1
BG64525B1 BG102797A BG10279798A BG64525B1 BG 64525 B1 BG64525 B1 BG 64525B1 BG 102797 A BG102797 A BG 102797A BG 10279798 A BG10279798 A BG 10279798A BG 64525 B1 BG64525 B1 BG 64525B1
Authority
BG
Bulgaria
Prior art keywords
alkoxy
alkyl
carbonic anhydrase
macular edema
halogen
Prior art date
Application number
BG102797A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102797A (en
Inventor
William Sponsel
Alon Harris
Original Assignee
Advanced Research And Technology Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605642.9A external-priority patent/GB9605642D0/en
Application filed by Advanced Research And Technology Institute filed Critical Advanced Research And Technology Institute
Publication of BG102797A publication Critical patent/BG102797A/xx
Publication of BG64525B1 publication Critical patent/BG64525B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Eye Examination Apparatus (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG102797A 1996-02-26 1998-09-25 Използване инхибиторите на карбоанхидразата за лечение на оток на макулата BG64525B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1225096P 1996-02-26 1996-02-26
GBGB9605642.9A GB9605642D0 (en) 1996-03-18 1996-03-18 Treatment of macular edema

Publications (2)

Publication Number Publication Date
BG102797A BG102797A (en) 1999-09-30
BG64525B1 true BG64525B1 (bg) 2005-06-30

Family

ID=26308946

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102797A BG64525B1 (bg) 1996-02-26 1998-09-25 Използване инхибиторите на карбоанхидразата за лечение на оток на макулата

Country Status (26)

Country Link
EP (1) EP0954305B9 (pt)
JP (1) JP4392481B2 (pt)
KR (1) KR100471586B1 (pt)
CN (1) CN1225582A (pt)
AT (1) ATE239468T1 (pt)
AU (1) AU727565B2 (pt)
BG (1) BG64525B1 (pt)
BR (1) BR9707674A (pt)
CA (1) CA2247063C (pt)
CZ (1) CZ299509B6 (pt)
DE (1) DE69721824T2 (pt)
DK (1) DK0954305T3 (pt)
EA (1) EA001681B1 (pt)
EE (1) EE03804B1 (pt)
ES (1) ES2199348T4 (pt)
HU (1) HU227161B1 (pt)
IL (1) IL125912A0 (pt)
IS (1) IS2053B (pt)
MX (1) MXPA98006961A (pt)
NO (1) NO320043B1 (pt)
NZ (1) NZ331843A (pt)
PT (1) PT954305E (pt)
SK (1) SK284371B6 (pt)
TR (1) TR199801665T2 (pt)
WO (1) WO1997030704A2 (pt)
YU (1) YU49422B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9803226D0 (en) 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
AU741525B2 (en) * 1998-03-06 2001-12-06 Board Of Regents, The University Of Texas System Composition and method for treating macular disorders
US5948801A (en) * 1998-03-09 1999-09-07 Alcon Laboratories, Inc. Treatment of retinal edema with brinzolamide
EP1104302A4 (en) * 1998-07-10 2006-08-09 Retmed Pty Ltd PROPHYLACTIC TREATMENTS OF BLOOD VESSEL NEOFORMATION IN MACULAR DEGENERATION
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902452D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902459D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902453D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000625D0 (en) 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
US20030100594A1 (en) * 2001-08-10 2003-05-29 Pharmacia Corporation Carbonic anhydrase inhibitor
EP2097421A2 (en) 2006-12-15 2009-09-09 Nicox S.A. Carbonic anhydrase inhibitors derivatives
AR084194A1 (es) * 2010-12-09 2013-04-24 Fovea Pharmaceuticals Derivados de arilsulfonamida para la prevencion o el tratamiento de trastornos oftalmologicos especificos
US10040804B2 (en) 2016-12-21 2018-08-07 Biotheryx, Inc. Compounds targeting proteins, compositions, methods, and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797413A (en) * 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
GB2223166B (en) * 1988-09-29 1992-03-18 American Cyanamid Co Stable ophthalmic preparations containing methazolamide
US5153192A (en) * 1990-04-09 1992-10-06 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors

Also Published As

Publication number Publication date
TR199801665T2 (xx) 1998-12-21
NO983906L (no) 1998-10-19
HU227161B1 (en) 2010-09-28
DE69721824T2 (de) 2004-03-11
YU35398A (sh) 2001-12-26
EP0954305A2 (en) 1999-11-10
KR19990087242A (ko) 1999-12-15
JP4392481B2 (ja) 2010-01-06
IS4829A (is) 1998-08-20
SK115198A3 (en) 2000-01-18
CA2247063C (en) 2004-01-06
WO1997030704A3 (en) 1997-09-25
ES2199348T3 (es) 2004-02-16
EA199800764A1 (ru) 1999-06-24
PT954305E (pt) 2003-09-30
MXPA98006961A (es) 2004-11-19
JP2000506833A (ja) 2000-06-06
CZ299509B6 (cs) 2008-08-20
YU49422B (sh) 2006-01-16
BG102797A (en) 1999-09-30
EP0954305B9 (en) 2010-08-04
HUP9902054A3 (en) 2001-07-30
ES2199348T4 (es) 2010-10-19
NO983906D0 (no) 1998-08-25
SK284371B6 (sk) 2005-02-04
EE03804B1 (et) 2002-08-15
EP0954305B1 (en) 2003-05-07
CA2247063A1 (en) 1997-08-28
DK0954305T3 (da) 2003-08-25
IL125912A0 (en) 1999-04-11
NZ331843A (en) 2000-09-29
KR100471586B1 (ko) 2005-07-11
WO1997030704A2 (en) 1997-08-28
CN1225582A (zh) 1999-08-11
BR9707674A (pt) 2000-01-04
IS2053B (is) 2005-10-14
EE9800263A (et) 1999-08-16
AU727565B2 (en) 2000-12-14
DE69721824D1 (de) 2003-06-12
AU1972197A (en) 1997-09-10
CZ269998A3 (cs) 2000-01-12
NO320043B1 (no) 2005-10-17
HUP9902054A1 (hu) 2000-03-28
ATE239468T1 (de) 2003-05-15
EA001681B1 (ru) 2001-06-25

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