BG62754B1 - Мукоадхезивна емулсия, съдържаща циклодекстрин - Google Patents

Мукоадхезивна емулсия, съдържаща циклодекстрин Download PDF

Info

Publication number
BG62754B1
BG62754B1 BG100955A BG10095596A BG62754B1 BG 62754 B1 BG62754 B1 BG 62754B1 BG 100955 A BG100955 A BG 100955A BG 10095596 A BG10095596 A BG 10095596A BG 62754 B1 BG62754 B1 BG 62754B1
Authority
BG
Bulgaria
Prior art keywords
cyclodextrin
composition
amount
itraconazole
emulsion
Prior art date
Application number
BG100955A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100955A (en
Inventor
Peter Putteman
Marc Francois
Eric Snoeckx
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of BG100955A publication Critical patent/BG100955A/xx
Publication of BG62754B1 publication Critical patent/BG62754B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
BG100955A 1994-05-18 1996-11-04 Мукоадхезивна емулсия, съдържаща циклодекстрин BG62754B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94201402 1994-05-18
PCT/EP1995/001760 WO1995031178A1 (en) 1994-05-18 1995-05-10 Mucoadhesive emulsions containing cyclodextrin

Publications (2)

Publication Number Publication Date
BG100955A BG100955A (en) 1998-04-30
BG62754B1 true BG62754B1 (bg) 2000-07-31

Family

ID=8216883

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100955A BG62754B1 (bg) 1994-05-18 1996-11-04 Мукоадхезивна емулсия, съдържаща циклодекстрин

Country Status (30)

Country Link
US (1) US5814330A (zh)
EP (1) EP0759741B1 (zh)
JP (1) JP3862748B2 (zh)
KR (1) KR100369703B1 (zh)
CN (1) CN1091590C (zh)
AP (1) AP731A (zh)
AT (1) ATE174790T1 (zh)
AU (1) AU680767B2 (zh)
BG (1) BG62754B1 (zh)
BR (1) BR9507873A (zh)
CZ (1) CZ285606B6 (zh)
DE (1) DE69506857T2 (zh)
DK (1) DK0759741T3 (zh)
EE (1) EE03304B1 (zh)
ES (1) ES2127529T3 (zh)
FI (1) FI964589A0 (zh)
HK (1) HK1010688A1 (zh)
HU (1) HU218082B (zh)
IL (1) IL113742A (zh)
MY (1) MY113846A (zh)
NO (1) NO309507B1 (zh)
NZ (1) NZ285761A (zh)
OA (1) OA10321A (zh)
PL (1) PL179619B1 (zh)
RO (1) RO117145B1 (zh)
RU (1) RU2164418C2 (zh)
SK (1) SK282623B6 (zh)
TW (1) TW438601B (zh)
WO (1) WO1995031178A1 (zh)
ZA (1) ZA954023B (zh)

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JP2002505661A (ja) * 1996-10-24 2002-02-19 ザ、プロクター、エンド、ギャンブル、カンパニー 体臭軽減方法及び組成物
US6416779B1 (en) * 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
ES2185238T3 (es) 1997-12-31 2003-04-16 Choongwae Pharma Corp Preparado oral de itraconazol y su procedimiento de preparacion.
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
NZ330726A (en) * 1998-06-18 2000-10-27 Dec Res Intra-vaginal delivery unit or composition containing a cyclodextrin which improves absorbtion of 17-beta oestradiol or oestradiol benzoate
GB9920167D0 (en) * 1999-08-25 1999-10-27 Avery Dennison Corp Pressure sensitive adhesive compositions
AU1911400A (en) * 1999-11-09 2001-06-06 Procter & Gamble Company, The Cyclodextrin compositions for odor, insect and dust mite contol
US6835717B2 (en) * 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
KR100388605B1 (ko) * 2000-06-13 2003-06-25 코오롱제약주식회사 용해도 및 용해속도가 향상된 이트라코나졸의 액상 조성물 및 이를 이용한 이트라코나졸 제제와 그 제조방법
US20020013331A1 (en) 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
EP1997478B1 (en) 2001-02-15 2013-09-04 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US7544348B2 (en) 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
CA2789114C (en) * 2001-11-01 2014-03-25 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
CN101259289B (zh) * 2001-11-02 2012-05-30 嵌入治疗公司 用于rna干扰的治疗用途的方法及组合物
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US20030144362A1 (en) * 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
US6824763B2 (en) 2002-05-30 2004-11-30 Kimberly-Clark Worldwide, Inc. Anti-fungal powder having enhanced excipient properties
US7977532B2 (en) 2002-09-05 2011-07-12 The Procter & Gamble Company Tampon with clean appearance post use
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
SG146638A1 (en) 2003-09-19 2008-10-30 Drugtech Corp Pharmaceutical delivery system
US20060024372A1 (en) * 2004-07-29 2006-02-02 Utterberg David S High viscosity antibacterials
US9028852B2 (en) * 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
AU2005314426A1 (en) 2004-12-10 2006-06-15 Talima Therapeutics, Inc. Compositions and methods for treating conditions of the nail unit
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
MX2007013631A (es) * 2005-05-09 2008-01-24 Drugtech Corp Composiciones farmaceuticas de liberacion modificada.
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CA2635986A1 (en) * 2006-01-05 2007-07-12 Drugtech Corporation Composition and method of use thereof
BRPI0620907A2 (pt) * 2006-01-05 2011-11-29 Drugtech Corp composição farmacêutica, sistema de distribuição de droga vaginal e uso da composição farmacêutica
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US20090123390A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Compositions for the treatment of gastrointestinal inflammation
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
CA2704946C (en) 2007-11-13 2013-09-24 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
RU2499592C2 (ru) 2008-04-21 2013-11-27 Отономи, Инк. Фармацевтическая композиция для лечения ушных заболеваний
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
US8784870B2 (en) * 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
WO2010011605A2 (en) 2008-07-21 2010-01-28 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
HUE051538T2 (hu) 2008-08-20 2021-03-01 Univ California Kortikoszteroidok a gyomor-bél traktus gyulladásos betegségeinek kezelésére
AU2014241396A1 (en) 2013-03-14 2015-09-17 Hallux, Inc. Method of treating infections, diseases or disorders of nail unit
AU2016298307A1 (en) 2015-07-28 2018-02-15 Otonomy, Inc. TrkB or TrkC agonist compositions and methods for the treatment of OTIC conditions
JP7033789B2 (ja) 2016-06-29 2022-03-11 オトノミー,インク. トリグリセリド耳用製剤とその使用
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
EP0335545B2 (en) * 1988-03-29 1998-09-23 University Of Florida Pharmaceutical formulations for parenteral use
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
IT1250421B (it) * 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
AU661754B2 (en) * 1992-02-12 1995-08-03 Janssen - Cilag - S.p.a. Liposomal itraconazole formulations
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
FR2719999B1 (fr) * 1994-05-17 1996-08-02 Georges Serge Grimberg Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques.

Also Published As

Publication number Publication date
ES2127529T3 (es) 1999-04-16
CZ285606B6 (cs) 1999-09-15
SK146996A3 (en) 1997-05-07
HU218082B (hu) 2000-05-28
NO309507B1 (no) 2001-02-12
NO964853L (no) 1996-11-15
NZ285761A (en) 1997-05-26
DE69506857T2 (de) 1999-08-05
JPH10500121A (ja) 1998-01-06
NO964853D0 (no) 1996-11-15
US5814330A (en) 1998-09-29
IL113742A0 (en) 1995-08-31
FI964589A (fi) 1996-11-15
AP9600873A0 (en) 1996-10-31
EP0759741B1 (en) 1998-12-23
PL179619B1 (pl) 2000-10-31
HK1010688A1 (en) 1999-06-25
EE03304B1 (et) 2000-12-15
RO117145B1 (ro) 2001-11-30
HU9603188D0 (en) 1997-01-28
TW438601B (en) 2001-06-07
CN1091590C (zh) 2002-10-02
JP3862748B2 (ja) 2006-12-27
BG100955A (en) 1998-04-30
EP0759741A1 (en) 1997-03-05
KR100369703B1 (ko) 2003-04-16
FI964589A0 (fi) 1996-11-15
PL317257A1 (en) 1997-04-01
OA10321A (en) 1997-10-07
AU680767B2 (en) 1997-08-07
DK0759741T3 (da) 1999-08-23
CN1148335A (zh) 1997-04-23
CZ336996A3 (en) 1997-02-12
KR970702719A (ko) 1997-06-10
DE69506857D1 (de) 1999-02-04
IL113742A (en) 1999-09-22
ATE174790T1 (de) 1999-01-15
MY113846A (en) 2002-06-29
AU2526495A (en) 1995-12-05
HUT76326A (en) 1997-08-28
ZA954023B (en) 1996-11-18
BR9507873A (pt) 1997-09-23
SK282623B6 (sk) 2002-10-08
RU2164418C2 (ru) 2001-03-27
AP731A (en) 1999-02-08
WO1995031178A1 (en) 1995-11-23

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