BG62208B1 - 2,3,4,5-тетрахидро-1н-3-бензазепини, метод за получаванетоим, тяхното приложение и това на фармацевтично приемливите имприсъединителни с киселини соли - Google Patents

2,3,4,5-тетрахидро-1н-3-бензазепини, метод за получаванетоим, тяхното приложение и това на фармацевтично приемливите имприсъединителни с киселини соли Download PDF

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Publication number
BG62208B1
BG62208B1 BG98993A BG9899394A BG62208B1 BG 62208 B1 BG62208 B1 BG 62208B1 BG 98993 A BG98993 A BG 98993A BG 9899394 A BG9899394 A BG 9899394A BG 62208 B1 BG62208 B1 BG 62208B1
Authority
BG
Bulgaria
Prior art keywords
compound
chloro
tetrahydro
benzazepine
methyl
Prior art date
Application number
BG98993A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98993A (bg
Inventor
Christian Foged
Rolf Hohlweg
Erik B. Nielsen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of BG98993A publication Critical patent/BG98993A/bg
Publication of BG62208B1 publication Critical patent/BG62208B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BG98993A 1992-02-24 1994-08-22 2,3,4,5-тетрахидро-1н-3-бензазепини, метод за получаванетоим, тяхното приложение и това на фармацевтично приемливите имприсъединителни с киселини соли BG62208B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling
PCT/DK1993/000041 WO1993017012A1 (en) 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepines and pharmaceutically acceptable acid addition salts thereof

Publications (2)

Publication Number Publication Date
BG98993A BG98993A (bg) 1995-05-31
BG62208B1 true BG62208B1 (bg) 1999-05-31

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98993A BG62208B1 (bg) 1992-02-24 1994-08-22 2,3,4,5-тетрахидро-1н-3-бензазепини, метод за получаванетоим, тяхното приложение и това на фармацевтично приемливите имприсъединителни с киселини соли

Country Status (23)

Country Link
EP (1) EP0628039B1 (da)
JP (1) JPH07504172A (da)
KR (1) KR100255739B1 (da)
AT (1) ATE152450T1 (da)
AU (1) AU667878B2 (da)
BG (1) BG62208B1 (da)
CA (1) CA2130678C (da)
CZ (1) CZ288626B6 (da)
DE (1) DE69310353T2 (da)
DK (2) DK23392D0 (da)
ES (1) ES2102019T3 (da)
FI (1) FI113770B (da)
GR (1) GR3023896T3 (da)
HU (1) HU221314B1 (da)
IL (1) IL104657A (da)
NO (1) NO310193B1 (da)
NZ (1) NZ249465A (da)
RO (1) RO116088B1 (da)
RU (1) RU2114839C1 (da)
SK (1) SK281390B6 (da)
UA (1) UA34451C2 (da)
WO (1) WO1993017012A1 (da)
ZA (1) ZA931099B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1945495A (en) * 1994-03-16 1995-10-03 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
EP0850237A1 (en) * 1995-09-15 1998-07-01 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
MX368959B (es) 2012-10-25 2019-10-23 Tetra Discovery Partners Llc Inhibidores heteroarilo de pde4.
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
KR100255739B1 (ko) 2000-05-01
NZ249465A (en) 1996-02-27
EP0628039A1 (en) 1994-12-14
IL104657A0 (en) 1993-06-10
EP0628039B1 (en) 1997-05-02
FI943875A0 (fi) 1994-08-23
CZ288626B6 (cs) 2001-08-15
CZ198894A3 (en) 1995-10-18
FI943875A (fi) 1994-08-23
NO310193B1 (no) 2001-06-05
DK0628039T3 (da) 1997-12-08
CA2130678A1 (en) 1993-08-25
HU221314B1 (en) 2002-09-28
CA2130678C (en) 2004-04-20
ATE152450T1 (de) 1997-05-15
RU2114839C1 (ru) 1998-07-10
UA34451C2 (uk) 2001-03-15
HU9402434D0 (en) 1994-10-28
IL104657A (en) 1999-11-30
DK23392D0 (da) 1992-02-24
BG98993A (bg) 1995-05-31
DE69310353D1 (de) 1997-06-05
ZA931099B (en) 1994-08-17
DE69310353T2 (de) 1997-10-02
ES2102019T3 (es) 1997-07-16
FI113770B (fi) 2004-06-15
KR950700286A (ko) 1995-01-16
JPH07504172A (ja) 1995-05-11
SK100094A3 (en) 1995-04-12
RO116088B1 (ro) 2000-10-30
NO943123D0 (no) 1994-08-24
WO1993017012A1 (en) 1993-09-02
AU667878B2 (en) 1996-04-18
NO943123L (no) 1994-08-24
GR3023896T3 (en) 1997-09-30
SK281390B6 (sk) 2001-03-12
HUT71127A (en) 1995-11-28
AU3626593A (en) 1993-09-13
RU94040719A (ru) 1996-07-10

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