BG60949B1 - Антихипертензивно средство - Google Patents
Антихипертензивно средство Download PDFInfo
- Publication number
- BG60949B1 BG60949B1 BG96664A BG9666492A BG60949B1 BG 60949 B1 BG60949 B1 BG 60949B1 BG 96664 A BG96664 A BG 96664A BG 9666492 A BG9666492 A BG 9666492A BG 60949 B1 BG60949 B1 BG 60949B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- pyridazodiazepine
- alkyl
- formula
- benzimidazolyl
- agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- External Artificial Organs (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH219191 | 1991-07-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
BG96664A BG96664A (bg) | 1993-12-24 |
BG60949B1 true BG60949B1 (bg) | 1996-07-31 |
Family
ID=4228024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG96664A BG60949B1 (bg) | 1991-07-23 | 1992-07-21 | Антихипертензивно средство |
Country Status (31)
Country | Link |
---|---|
US (1) | US5620975A (pt) |
EP (1) | EP0524512B1 (pt) |
JP (1) | JPH0680009B2 (pt) |
KR (1) | KR100260479B1 (pt) |
CN (1) | CN1040505C (pt) |
AT (1) | ATE260661T1 (pt) |
AU (1) | AU656207B2 (pt) |
BG (1) | BG60949B1 (pt) |
BR (1) | BR9202830A (pt) |
CA (1) | CA2074039C (pt) |
CZ (1) | CZ281691B6 (pt) |
DE (1) | DE59209993D1 (pt) |
DK (1) | DK0524512T3 (pt) |
ES (1) | ES2215160T3 (pt) |
HR (1) | HRP930953B1 (pt) |
HU (1) | HU214029B (pt) |
IE (1) | IE922378A1 (pt) |
IL (1) | IL102541A (pt) |
IS (1) | IS3887A (pt) |
MX (1) | MX9204212A (pt) |
MY (1) | MY118064A (pt) |
NO (1) | NO301047B1 (pt) |
NZ (1) | NZ243577A (pt) |
PT (1) | PT524512E (pt) |
RO (1) | RO110905B (pt) |
RU (1) | RU2084225C1 (pt) |
SK (1) | SK278918B6 (pt) |
TW (1) | TW216770B (pt) |
UY (1) | UY23449A1 (pt) |
YU (2) | YU49198B (pt) |
ZA (1) | ZA925322B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0634175B1 (de) * | 1993-07-15 | 2001-01-10 | F. Hoffmann-La Roche Ag | Pharmazeutische Kombination, die einen Hemmer des Renin-Angiotensin-Systems und einen Endothelin-Antagonisten enthält |
IL131816A (en) | 1997-04-04 | 2003-06-24 | Exxon Res & Engineering Compan | Composite structures having high containment strength |
EP1438297A1 (en) | 2001-10-10 | 2004-07-21 | Aryx Therapeutics | Mibefradil-based compounds as calcium channel blockers useful in the treatment of hypertension and angina |
US7687086B1 (en) | 2003-02-28 | 2010-03-30 | University Of Portland | Method for obtaining taxanes |
EP2537534B1 (en) | 2011-06-22 | 2014-12-17 | Hexal AG | Esters of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their therapeutic use. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
DE3542794A1 (de) * | 1985-12-04 | 1987-06-11 | Bayer Ag | Antihypertensives kombinationspraeparat |
CA1319144C (en) * | 1986-11-14 | 1993-06-15 | Quirico Branca | Tetrahydronaphthalene derivatives |
FR2607004B1 (fr) * | 1986-11-20 | 1990-06-01 | Synthelabo | Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine |
US5110813A (en) * | 1987-09-15 | 1992-05-05 | Alcoholism And Drug Addiction Research Foundation | Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors |
US4871731A (en) * | 1987-10-07 | 1989-10-03 | Marion Laboratories, Inc. | Captopril and diltiazem composition and the like |
KR940005408B1 (ko) * | 1990-12-03 | 1994-06-18 | 만도기계 주식회사 | 파워 윈도우 모우터 회전자의 선단부 흔들림 측정장치 |
-
1992
- 1992-07-04 TW TW081105301A patent/TW216770B/zh active
- 1992-07-11 PT PT92111847T patent/PT524512E/pt unknown
- 1992-07-11 EP EP92111847A patent/EP0524512B1/de not_active Expired - Lifetime
- 1992-07-11 AT AT92111847T patent/ATE260661T1/de not_active IP Right Cessation
- 1992-07-11 DK DK92111847T patent/DK0524512T3/da active
- 1992-07-11 DE DE59209993T patent/DE59209993D1/de not_active Expired - Fee Related
- 1992-07-11 ES ES92111847T patent/ES2215160T3/es not_active Expired - Lifetime
- 1992-07-16 ZA ZA925322A patent/ZA925322B/xx unknown
- 1992-07-16 NZ NZ243577A patent/NZ243577A/en unknown
- 1992-07-16 CA CA002074039A patent/CA2074039C/en not_active Expired - Fee Related
- 1992-07-17 MX MX9204212A patent/MX9204212A/es active IP Right Grant
- 1992-07-17 IL IL10254192A patent/IL102541A/en not_active IP Right Cessation
- 1992-07-20 RU SU925052378A patent/RU2084225C1/ru not_active IP Right Cessation
- 1992-07-20 HU HU9202367A patent/HU214029B/hu not_active IP Right Cessation
- 1992-07-20 AU AU20416/92A patent/AU656207B2/en not_active Ceased
- 1992-07-21 MY MYPI92001289A patent/MY118064A/en unknown
- 1992-07-21 KR KR1019920012932A patent/KR100260479B1/ko not_active IP Right Cessation
- 1992-07-21 RO RO92-0990A patent/RO110905B/ro unknown
- 1992-07-21 SK SK2270-92A patent/SK278918B6/sk unknown
- 1992-07-21 BG BG96664A patent/BG60949B1/bg unknown
- 1992-07-21 CZ CS922270A patent/CZ281691B6/cs not_active IP Right Cessation
- 1992-07-22 UY UY23449A patent/UY23449A1/es not_active IP Right Cessation
- 1992-07-22 IE IE237892A patent/IE922378A1/en not_active Application Discontinuation
- 1992-07-22 CN CN92108668A patent/CN1040505C/zh not_active Expired - Fee Related
- 1992-07-22 NO NO922903A patent/NO301047B1/no not_active IP Right Cessation
- 1992-07-23 YU YU72392A patent/YU49198B/sh unknown
- 1992-07-23 JP JP4216629A patent/JPH0680009B2/ja not_active Expired - Fee Related
- 1992-07-23 BR BR929202830A patent/BR9202830A/pt not_active Application Discontinuation
- 1992-07-23 IS IS3887A patent/IS3887A/is unknown
- 1992-07-23 YU YU72392A patent/YU72392A/sh unknown
-
1993
- 1993-06-07 HR HR930953A patent/HRP930953B1/xx not_active IP Right Cessation
-
1994
- 1994-11-02 US US08/333,171 patent/US5620975A/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8980832B2 (en) | Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma | |
US7834056B2 (en) | Pharmaceutical composition for gout | |
EP0786991B1 (en) | Polyamine compounds for treating vascular proliferative disorders | |
US5624945A (en) | Use of riluzole for the treatment of neuro-aids | |
EA002525B1 (ru) | Сочетание ингибитора тирозинкиназы и химической стерилизации для лечения рака предстательной железы | |
US5028628A (en) | Methods of treating pulmonary hypertension | |
BG60949B1 (bg) | Антихипертензивно средство | |
US6844361B2 (en) | Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor | |
RU2432948C2 (ru) | Применение активаторов растворимой гуанилатциклазы для лечения нарушений кровоснабжения | |
WO1997048396A1 (en) | A method of treating liver disease and like indications with vasodilating agents | |
JP4733348B2 (ja) | 心不全、他の加齢関連臓器機能不全および加齢関連障害の予防のための、ならびに寿命を延長するための、ナトリウム−水素交換阻害剤であるカリポライドとace阻害剤との組み合わせ製剤 | |
US3622671A (en) | Substituted 3-hydrazino pyridazines as hypotensives | |
JPWO2003047591A1 (ja) | 肺高血圧症予防治療剤 | |
JPS6396124A (ja) | アニパミル含有医薬 | |
JPH01283224A (ja) | 抗高血圧の組み合わせ調合物 | |
NZ273242A (en) | Treatment of liver disease by administration of a vasodilator which increases the oxygen supply to the liver; pharmaceutical compositions | |
IE43955B1 (en) | Pharmaceutical composition and dosage units thereof | |
JPWO2018034351A1 (ja) | 生薬成分を含む肺高血圧症の予防又は治療剤 | |
Salzmann et al. | Effects of the vasodilator endralazine given with the antihypertensive agent guanfacine on heart rate and blood pressure of spontaneously hypertensive rats and normotensive dogs | |
HU197214B (en) | Process for producing pharmaceutical compositions containing 3-etoxycarbonyl-1,6-dimetil-4-oxo-6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidinium-methosulfate as active component for preventing and treating gastrointestinal damages | |
JPH0761939B2 (ja) | 脳への酸素供給を増進させる薬剤組成物および該薬剤組成物の製造方法 |