BG60840B2 - Сднк клонове кодиращи полипептиди,проявяващи активността на клетъчни растежни фактори за човешки гранулоцити,макрофаги и еозинофили - Google Patents

Сднк клонове кодиращи полипептиди,проявяващи активността на клетъчни растежни фактори за човешки гранулоцити,макрофаги и еозинофили Download PDF

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Publication number
BG60840B2
BG60840B2 BG98563A BG9856394A BG60840B2 BG 60840 B2 BG60840 B2 BG 60840B2 BG 98563 A BG98563 A BG 98563A BG 9856394 A BG9856394 A BG 9856394A BG 60840 B2 BG60840 B2 BG 60840B2
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BG
Bulgaria
Prior art keywords
cag
ctg
gag
acc
ccc
Prior art date
Application number
BG98563A
Other languages
Bulgarian (bg)
English (en)
Inventor
Takashi Yokota
Frank Lee
Donna Rennick
Ken-Ichi Arai
Original Assignee
Schering Biotech Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corporation filed Critical Schering Biotech Corporation
Publication of BG60840B2 publication Critical patent/BG60840B2/bg

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
BG98563A 1984-11-20 1994-02-24 Сднк клонове кодиращи полипептиди,проявяващи активността на клетъчни растежни фактори за човешки гранулоцити,макрофаги и еозинофили BG60840B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67389884A 1984-11-20 1984-11-20

Publications (1)

Publication Number Publication Date
BG60840B2 true BG60840B2 (bg) 1996-04-30

Family

ID=24704538

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98563A BG60840B2 (bg) 1984-11-20 1994-02-24 Сднк клонове кодиращи полипептиди,проявяващи активността на клетъчни растежни фактори за човешки гранулоцити,макрофаги и еозинофили

Country Status (26)

Country Link
EP (1) EP0202300B1 (hu)
JP (1) JP3038348B2 (hu)
KR (1) KR920003822B1 (hu)
CN (3) CN1031465C (hu)
AT (1) ATE82321T1 (hu)
AU (1) AU608741B2 (hu)
BG (1) BG60840B2 (hu)
DE (1) DE3586826T2 (hu)
DK (1) DK174598B1 (hu)
ES (1) ES8705470A1 (hu)
FI (1) FI103986B (hu)
GR (1) GR852786B (hu)
HK (1) HK6096A (hu)
HU (1) HU213226B (hu)
IE (1) IE59581B1 (hu)
IL (1) IL77080A (hu)
LU (1) LU88360I2 (hu)
MX (1) MX9203397A (hu)
MY (1) MY101971A (hu)
NL (1) NL930120I2 (hu)
NO (1) NO862903L (hu)
NZ (1) NZ214225A (hu)
OA (1) OA08671A (hu)
PT (1) PT81513B (hu)
WO (1) WO1986003225A1 (hu)
ZA (1) ZA858833B (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
UA29377C2 (uk) * 1984-09-19 2000-11-15 Новартіс Аг Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
US5078996A (en) * 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
JPS63502795A (ja) * 1985-10-03 1988-10-20 バイオジェン インコーポレイテッド 顆粒球‐マクロファージコロニー刺激因子‐様ポリペプチド、ｄｎａ配列、組換えｄｎａ分子並びに微生物細胞中でヒト顆粒球−マクロファ−ジコロニ−刺激因子−様ポリペプチドを高収量で生産する方法
JPH0618778B2 (ja) * 1985-10-04 1994-03-16 中外製薬株式会社 白血球減少症治療剤
US5298603A (en) * 1985-12-21 1994-03-29 Hoechst Aktiengesellschaft GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
EP0276846A3 (en) * 1987-01-29 1989-07-26 Zymogenetics, Inc. Colony-stimulating factor derivatives
JPS6420097A (en) * 1987-03-02 1989-01-24 Sumitomo Chemical Co Human granulocyte-macrophage colony stimulating factor
WO1988008428A1 (en) * 1987-04-28 1988-11-03 Amgen Inc. Method for purifying granulocyte/macrophage colony stimulating factor
AU626530B2 (en) * 1987-07-17 1992-08-06 Schering Biotech Corporation Human granulocyte-macrophage colony stimulating factor and muteins thereof
IE63514B1 (en) * 1987-07-17 1995-05-03 Schering Biotech Corp Expression vectors for the production of human granulocyte-macrophage colony stimulation factor in a mammalian cell host
GB2212159B (en) * 1987-11-13 1992-01-22 British Bio Technology Synthetic gene for human granulocyte/macrophage colony stimulating factor.
WO1989010403A1 (en) * 1988-04-21 1989-11-02 Medvet Science Pty. Ltd. Human gm-csf variants
US5109119A (en) * 1989-06-06 1992-04-28 Schering Corporation Crystalline r-h-gm-csf and method
KR100448021B1 (ko) * 2001-12-28 2004-09-08 크레아젠 주식회사 마우스 과립구 대식세포 콜로니 촉진인자 발현벡터 ｐＧＭ-ＣＳＦ로 형질전환된 대장균 및 상기 마우스 과립구 대식세포 콜로니 촉진인자의 대량생산방법
EP1540627A4 (en) * 2002-09-20 2006-08-16 Dendreon Corp IMMUNOTHERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING MODERATELY DIFFERENTIATED CANCERS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
WO1986000639A1 (en) * 1984-07-06 1986-01-30 Sandoz Ag Lymphokine production and purification
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene

Also Published As

Publication number Publication date
PT81513B (pt) 1988-03-03
HUT40464A (en) 1986-12-28
NZ214225A (en) 1991-05-28
NO862903D0 (no) 1986-07-18
ES548998A0 (es) 1987-05-01
CN85109132A (zh) 1986-12-03
MY101971A (en) 1992-02-29
KR920003822B1 (ko) 1992-05-15
AU5196386A (en) 1986-06-18
WO1986003225A1 (en) 1986-06-05
FI862674A0 (fi) 1986-06-24
PT81513A (en) 1985-12-01
AU608741B2 (en) 1991-04-18
ZA858833B (en) 1986-06-25
GR852786B (hu) 1986-03-20
CN1086543A (zh) 1994-05-11
NO862903L (no) 1986-09-18
IL77080A (en) 1998-02-08
LU88360I2 (fr) 1994-05-04
NL930120I1 (nl) 1993-11-01
DE3586826D1 (de) 1992-12-17
JP3038348B2 (ja) 2000-05-08
DK174598B1 (da) 2003-07-14
DK345286A (da) 1986-07-21
KR860700359A (ko) 1986-10-06
IL77080A0 (en) 1986-04-29
JPS62501259A (ja) 1987-05-21
CN1020473C (zh) 1993-05-05
DK345286D0 (da) 1986-07-21
CN1045539C (zh) 1999-10-13
ATE82321T1 (de) 1992-11-15
FI103986B1 (fi) 1999-10-29
FI862674A (fi) 1986-06-24
FI103986B (fi) 1999-10-29
DE3586826T2 (de) 1993-03-25
CN1031465C (zh) 1996-04-03
EP0202300A1 (en) 1986-11-26
IE852889L (en) 1986-05-20
IE59581B1 (en) 1994-03-09
HK6096A (en) 1996-01-19
EP0202300B1 (en) 1992-11-11
OA08671A (en) 1989-03-31
NL930120I2 (nl) 1994-07-01
MX9203397A (es) 1992-07-01
ES8705470A1 (es) 1987-05-01
HU213226B (en) 1997-03-28

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