ATE82321T1 - Cdna-klone, kodierend fuer peptide mit der wirksamkeit eines menschlichen granulocyte-, makrophage- und eosinophilzellenwachstumsfaktors. - Google Patents

Cdna-klone, kodierend fuer peptide mit der wirksamkeit eines menschlichen granulocyte-, makrophage- und eosinophilzellenwachstumsfaktors.

Info

Publication number
ATE82321T1
ATE82321T1 AT85906001T AT85906001T ATE82321T1 AT E82321 T1 ATE82321 T1 AT E82321T1 AT 85906001 T AT85906001 T AT 85906001T AT 85906001 T AT85906001 T AT 85906001T AT E82321 T1 ATE82321 T1 AT E82321T1
Authority
AT
Austria
Prior art keywords
cdna
growth factor
macrophage
human granulocyte
cell growth
Prior art date
Application number
AT85906001T
Other languages
English (en)
Inventor
Takashi Yokota
Frank Don Lee
Donna Maye Rennick
Ken-Ichi Arai
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Application granted granted Critical
Publication of ATE82321T1 publication Critical patent/ATE82321T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
AT85906001T 1984-11-20 1985-11-18 Cdna-klone, kodierend fuer peptide mit der wirksamkeit eines menschlichen granulocyte-, makrophage- und eosinophilzellenwachstumsfaktors. ATE82321T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67389884A 1984-11-20 1984-11-20
EP85906001A EP0202300B1 (de) 1984-11-20 1985-11-18 Cdna-klone, kodierend für peptide mit der wirksamkeit eines menschlichen granulocyte-, makrophage- und eosinophilzellenwachstumsfaktors
PCT/US1985/002250 WO1986003225A1 (en) 1984-11-20 1985-11-18 cDNA CLONES CODING FOR POLYPEPTIDES EXHIBITING HUMAN GRANULOCYTE MACROPHAGE AND EOSINOPHIL CELLULAR GROWTH FACTOR ACTIVITY

Publications (1)

Publication Number Publication Date
ATE82321T1 true ATE82321T1 (de) 1992-11-15

Family

ID=24704538

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85906001T ATE82321T1 (de) 1984-11-20 1985-11-18 Cdna-klone, kodierend fuer peptide mit der wirksamkeit eines menschlichen granulocyte-, makrophage- und eosinophilzellenwachstumsfaktors.

Country Status (26)

Country Link
EP (1) EP0202300B1 (de)
JP (1) JP3038348B2 (de)
KR (1) KR920003822B1 (de)
CN (3) CN1020473C (de)
AT (1) ATE82321T1 (de)
AU (1) AU608741B2 (de)
BG (1) BG60840B2 (de)
DE (1) DE3586826T2 (de)
DK (1) DK174598B1 (de)
ES (1) ES8705470A1 (de)
FI (1) FI103986B1 (de)
GR (1) GR852786B (de)
HK (1) HK6096A (de)
HU (1) HU213226B (de)
IE (1) IE59581B1 (de)
IL (1) IL77080A (de)
LU (1) LU88360I2 (de)
MX (1) MX9203397A (de)
MY (1) MY101971A (de)
NL (1) NL930120I2 (de)
NO (1) NO862903L (de)
NZ (1) NZ214225A (de)
OA (1) OA08671A (de)
PT (1) PT81513B (de)
WO (1) WO1986003225A1 (de)
ZA (1) ZA858833B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
UA29377C2 (uk) * 1984-09-19 2000-11-15 Новартіс Аг Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
US5078996A (en) * 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
JPS63502795A (ja) * 1985-10-03 1988-10-20 バイオジェン インコーポレイテッド 顆粒球‐マクロファージコロニー刺激因子‐様ポリペプチド、ｄｎａ配列、組換えｄｎａ分子並びに微生物細胞中でヒト顆粒球−マクロファ−ジコロニ−刺激因子−様ポリペプチドを高収量で生産する方法
JPH0618778B2 (ja) * 1985-10-04 1994-03-16 中外製薬株式会社 白血球減少症治療剤
US5298603A (en) * 1985-12-21 1994-03-29 Hoechst Aktiengesellschaft GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
EP0276846A3 (de) * 1987-01-29 1989-07-26 Zymogenetics, Inc. Derivate des koloniestimulierenden Faktors
JPS6420097A (en) * 1987-03-02 1989-01-24 Sumitomo Chemical Co Human granulocyte-macrophage colony stimulating factor
AU621051B2 (en) * 1987-04-28 1992-03-05 Amgen, Inc. Method for purifying granulocyte-macrophage colony stimulating factor
ZA885101B (en) * 1987-07-17 1989-03-29 Schering Biotech Corp Human granulocyte macrophage colony stimulating factor and muteins thereof
AU626530B2 (en) * 1987-07-17 1992-08-06 Schering Biotech Corporation Human granulocyte-macrophage colony stimulating factor and muteins thereof
GB2212159B (en) * 1987-11-13 1992-01-22 British Bio Technology Synthetic gene for human granulocyte/macrophage colony stimulating factor.
JPH03503897A (ja) * 1988-04-21 1991-08-29 メドベット・サイエンス・プロプライアテリー・リミテッド ひとｇｍ‐ｃｓｆ変異形類
US5109119A (en) * 1989-06-06 1992-04-28 Schering Corporation Crystalline r-h-gm-csf and method
KR100448021B1 (ko) * 2001-12-28 2004-09-08 크레아젠 주식회사 마우스 과립구 대식세포 콜로니 촉진인자 발현벡터 ｐＧＭ-ＣＳＦ로 형질전환된 대장균 및 상기 마우스 과립구 대식세포 콜로니 촉진인자의 대량생산방법
CA2497554A1 (en) * 2002-09-20 2004-04-01 Dendreon Corporation Immunotherapeutic compositions and methods for the treatment of moderately to well-differentiated cancers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
IE60819B1 (en) * 1984-07-06 1994-08-10 Sandoz Ltd Lymphokine production and purification
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene

Also Published As

Publication number Publication date
JPS62501259A (ja) 1987-05-21
DE3586826T2 (de) 1993-03-25
NO862903D0 (no) 1986-07-18
KR920003822B1 (ko) 1992-05-15
NL930120I2 (nl) 1994-07-01
IE852889L (en) 1986-05-20
NO862903L (no) 1986-09-18
FI862674A0 (fi) 1986-06-24
DE3586826D1 (de) 1992-12-17
ES8705470A1 (es) 1987-05-01
ES548998A0 (es) 1987-05-01
NZ214225A (en) 1991-05-28
HK6096A (en) 1996-01-19
IE59581B1 (en) 1994-03-09
EP0202300B1 (de) 1992-11-11
HUT40464A (en) 1986-12-28
KR860700359A (ko) 1986-10-06
CN85109132A (zh) 1986-12-03
JP3038348B2 (ja) 2000-05-08
FI862674A (fi) 1986-06-24
CN1086543A (zh) 1994-05-11
WO1986003225A1 (en) 1986-06-05
DK345286A (da) 1986-07-21
CN1031465C (zh) 1996-04-03
CN1020473C (zh) 1993-05-05
MY101971A (en) 1992-02-29
DK345286D0 (da) 1986-07-21
AU608741B2 (en) 1991-04-18
LU88360I2 (fr) 1994-05-04
HU213226B (en) 1997-03-28
GR852786B (de) 1986-03-20
CN1045539C (zh) 1999-10-13
IL77080A (en) 1998-02-08
BG60840B2 (bg) 1996-04-30
DK174598B1 (da) 2003-07-14
FI103986B (fi) 1999-10-29
EP0202300A1 (de) 1986-11-26
ZA858833B (en) 1986-06-25
FI103986B1 (fi) 1999-10-29
IL77080A0 (en) 1986-04-29
PT81513B (pt) 1988-03-03
OA08671A (en) 1989-03-31
NL930120I1 (nl) 1993-11-01
PT81513A (en) 1985-12-01
AU5196386A (en) 1986-06-18
MX9203397A (es) 1992-07-01

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