BG46004A3 - Метод за получаване на оптично активни 2-хлор-12-/3-диметиламин-2- метилпропил/12н-дибензо-/d,g//1,3,6/-диоксазоцини - Google Patents

Метод за получаване на оптично активни 2-хлор-12-/3-диметиламин-2- метилпропил/12н-дибензо-/d,g//1,3,6/-диоксазоцини

Info

Publication number
BG46004A3
BG46004A3 BG077613A BG7761386A BG46004A3 BG 46004 A3 BG46004 A3 BG 46004A3 BG 077613 A BG077613 A BG 077613A BG 7761386 A BG7761386 A BG 7761386A BG 46004 A3 BG46004 A3 BG 46004A3
Authority
BG
Bulgaria
Prior art keywords
dibenzo
methylpropyl
dioxazocini
dimethylamin
chlor
Prior art date
Application number
BG077613A
Other languages
English (en)
Inventor
Laszlo Rozsa
Lujza Petoecz
Enikoe Szirt
Peter Toempe
Gabor Gigler
Original Assignee
Egis Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.
Publication of BG46004A3 publication Critical patent/BG46004A3/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02T—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO TRANSPORTATION
    • Y02T50/00—Aeronautics or air transport
    • Y02T50/10—Drag reduction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)

Abstract

Методът намира приложение във фармацевтичната промишленост за получаване на невролептици, използвани за лечение болестта на паркинсон. Оптично активните 2-хлор-12(3-диметил-2-метилпропил)-12н-дибензо-(d,g) (1, 3, 6)-диоксазоцини типт по-висока активност спрямо болестта на паркинсон от рацемичното съединение. 3 претенции
BG077613A 1985-12-20 1986-12-19 Метод за получаване на оптично активни 2-хлор-12-/3-диметиламин-2- метилпропил/12н-дибензо-/d,g//1,3,6/-диоксазоцини BG46004A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU854881A HU195491B (en) 1985-12-20 1985-12-20 Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds

Publications (1)

Publication Number Publication Date
BG46004A3 true BG46004A3 (bg) 1989-09-15

Family

ID=10969129

Family Applications (1)

Application Number Title Priority Date Filing Date
BG077613A BG46004A3 (bg) 1985-12-20 1986-12-19 Метод за получаване на оптично активни 2-хлор-12-/3-диметиламин-2- метилпропил/12н-дибензо-/d,g//1,3,6/-диоксазоцини

Country Status (27)

Country Link
US (1) US4906622A (bg)
JP (1) JPS62158265A (bg)
CN (1) CN86108260A (bg)
AT (1) AT394366B (bg)
AU (1) AU589725B2 (bg)
BE (1) BE905907A (bg)
BG (1) BG46004A3 (bg)
CA (1) CA1291133C (bg)
CH (1) CH670638A5 (bg)
CS (1) CS262681B2 (bg)
DD (1) DD256695A5 (bg)
DE (1) DE3643991A1 (bg)
DK (1) DK616886A (bg)
ES (1) ES2003994A6 (bg)
FI (1) FI83644C (bg)
FR (1) FR2592043B1 (bg)
GB (1) GB2184445B (bg)
HU (1) HU195491B (bg)
IT (1) IT1199821B (bg)
NL (1) NL8603236A (bg)
NO (1) NO865179L (bg)
PH (1) PH24385A (bg)
PL (1) PL263134A1 (bg)
PT (1) PT83979B (bg)
SE (1) SE466399B (bg)
SU (1) SU1470187A3 (bg)
YU (1) YU45814B (bg)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198194B (en) * 1986-12-30 1989-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of new derivatives of dioxazocin and medical compositions containing them
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same
ES2058761T3 (es) * 1989-10-20 1994-11-01 Akzo Nv Proceso para la preparacion de derivados de dibenzodioxazecina y dibenzodioxaazacicloundecina.
EP0851865B1 (en) * 1995-09-19 2002-07-17 Novo Nordisk A/S 12H-Dibenzo[d,g][1,3]dioxocine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2705M (fr) * 1963-04-18 1964-08-03 Rhone Poulenc Sa Nouvelles compositions anti-émétiques.
NL7202963A (bg) * 1972-03-07 1973-09-11
NL176458C (nl) * 1972-09-23 1985-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.
HU174126B (hu) * 1977-08-02 1979-11-28 Egyt Gyogyszervegyeszeti Gyar Sposob poluchenija novykh proizvodnykh dibenzo-kvadratnaja skobka-d,g-kvadratnaja skobka zakryta-kvadratnaja skobka-1,3,6-kvadratnaja skobka zakryta-dioksazocina
DE3426720A1 (de) * 1984-07-20 1986-01-23 Hoechst Ag, 6230 Frankfurt Benzthiazepinon- und benzthiazocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung

Also Published As

Publication number Publication date
AT394366B (de) 1992-03-25
DE3643991C2 (bg) 1990-08-09
CA1291133C (en) 1991-10-22
DD256695A5 (de) 1988-05-18
US4906622A (en) 1990-03-06
FI865244A (fi) 1987-06-21
ATA326986A (de) 1991-09-15
FR2592043A1 (fr) 1987-06-26
FI865244A0 (fi) 1986-12-19
BE905907A (fr) 1987-06-12
YU218886A (en) 1988-04-30
SE466399B (sv) 1992-02-10
HUT44247A (en) 1988-02-29
CS262681B2 (en) 1989-03-14
ES2003994A6 (es) 1988-12-01
IT8622780A0 (it) 1986-12-19
SU1470187A3 (ru) 1989-03-30
PL263134A1 (en) 1988-06-23
YU45814B (sh) 1992-07-20
PT83979B (pt) 1989-01-17
NO865179D0 (no) 1986-12-19
DK616886D0 (da) 1986-12-19
FI83644B (fi) 1991-04-30
GB2184445A (en) 1987-06-24
GB2184445B (en) 1989-10-18
HU195491B (en) 1988-05-30
FR2592043B1 (fr) 1991-10-11
SE8605457D0 (sv) 1986-12-18
NL8603236A (nl) 1987-07-16
DE3643991A1 (de) 1987-06-25
CN86108260A (zh) 1987-09-09
PH24385A (en) 1990-06-13
PT83979A (en) 1987-01-01
SE8605457L (sv) 1987-06-21
GB8630431D0 (en) 1987-01-28
IT1199821B (it) 1989-01-05
AU589725B2 (en) 1989-10-19
CH670638A5 (bg) 1989-06-30
JPS62158265A (ja) 1987-07-14
CS960686A2 (en) 1988-08-16
NO865179L (no) 1987-06-22
FI83644C (fi) 1991-08-12
AU6676586A (en) 1987-06-25
DK616886A (da) 1987-06-21

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