BG33886A3 - Method for heterocyclic compounds producing - Google Patents

Method for heterocyclic compounds producing

Info

Publication number
BG33886A3
BG33886A3 BG8151119A BG5111981A BG33886A3 BG 33886 A3 BG33886 A3 BG 33886A3 BG 8151119 A BG8151119 A BG 8151119A BG 5111981 A BG5111981 A BG 5111981A BG 33886 A3 BG33886 A3 BG 33886A3
Authority
BG
Bulgaria
Prior art keywords
heterocyclic compounds
compounds producing
producing
heterocyclic
compounds
Prior art date
Application number
BG8151119A
Other languages
Bulgarian (bg)
English (en)
Inventor
Walther
Schneider
Weber
Fuegner
Original Assignee
C. H. Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C. H. Boehringer Sohn,De filed Critical C. H. Boehringer Sohn,De
Publication of BG33886A3 publication Critical patent/BG33886A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20—[b, f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG8151119A 1980-03-08 1981-03-06 Method for heterocyclic compounds producing BG33886A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803008944 DE3008944A1 (de) 1980-03-08 1980-03-08 Dibenzimidazoazepine, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
BG33886A3 true BG33886A3 (en) 1983-05-16

Family

ID=6096617

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8151119A BG33886A3 (en) 1980-03-08 1981-03-06 Method for heterocyclic compounds producing

Country Status (29)

Country Link
US (1) US4313931A (fr)
EP (1) EP0035749B1 (fr)
JP (1) JPS56139484A (fr)
AU (1) AU535359B2 (fr)
BG (1) BG33886A3 (fr)
CA (1) CA1150253A (fr)
CS (2) CS221288B2 (fr)
DD (1) DD156708A5 (fr)
DE (2) DE3008944A1 (fr)
DK (1) DK154299C (fr)
ES (1) ES500150A0 (fr)
FI (1) FI70898C (fr)
GB (1) GB2071095B (fr)
GR (1) GR74805B (fr)
HK (1) HK63186A (fr)
HU (1) HU180628B (fr)
IE (1) IE51015B1 (fr)
IL (1) IL62309A (fr)
MX (1) MX6869E (fr)
NO (1) NO162073C (fr)
NZ (1) NZ196446A (fr)
PH (1) PH15839A (fr)
PL (1) PL132141B1 (fr)
PT (1) PT72631B (fr)
RO (1) RO81652B (fr)
SU (1) SU1015829A3 (fr)
UA (1) UA8041A1 (fr)
YU (1) YU42557B (fr)
ZA (1) ZA811500B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134672A1 (de) * 1981-09-02 1983-03-17 Boehringer Ingelheim KG, 6507 Ingelheim Heterocyclische verbindungen, ihre herstellung und verwendung
EP0130202A1 (fr) * 1982-12-30 1985-01-09 Beecham Group Plc Composes tetracycliques
DE4102148A1 (de) * 1991-01-25 1992-07-30 Boehringer Ingelheim Kg Verfahren zur herstellung von 3-amino-9,13b-dihydro-1h-dibenz-(c,f)imidazol(1,5-a)azepin-hydrochlorid
DE19542281C2 (de) * 1995-11-14 1997-12-04 Boehringer Ingelheim Kg Verwendung von Epinastin für die Behandlung der Migräne
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
DE19958460A1 (de) * 1999-12-03 2001-06-07 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Epinastine-Hydrochlorid in der hochschmelzenden Kristallmodifikation
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
DE10152973A1 (de) * 2001-10-26 2003-05-08 Boehringer Ingelheim Int Neue trockene und wässrige Epinastin-Sirup-Formulierung
JP4298212B2 (ja) * 2002-03-29 2009-07-15 大日本印刷株式会社 塩酸エピナスチン高融点型結晶の製造法
WO2003084932A1 (fr) * 2002-04-11 2003-10-16 Konica Minolta Chemical Co., Ltd. Procede de preparation de 6-aminomethyl-6,11-dihydro-5h-dibenz[b,e]azepine
JP4514017B2 (ja) * 2003-03-27 2010-07-28 大日本印刷株式会社 塩酸エピナスチンの製造方法
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
DK2522365T3 (en) 2004-11-24 2017-02-06 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods for its use
CN101217948A (zh) * 2005-07-08 2008-07-09 千寿制药株式会社 包含依匹那丁的透皮吸收眼科制剂
US7247623B2 (en) * 2005-08-19 2007-07-24 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with non-drying antihistamines
KR101386530B1 (ko) 2006-12-29 2014-04-18 케이피엑스 라이프사이언스 주식회사 순도 및 수율이 향상된3-아미노-9,13ｂ디하이드로-1Ｈ-디벤즈-[ｃ,ｆ]이미다조[1,5-ａ]-아제핀 염산염의 제조방법
WO2009063504A2 (fr) * 2007-09-24 2009-05-22 Usv Limited Nouvelle modification de cristaux d'épinastine ou de sels de ce composé et processus de préparation de ceux-ci
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
JP2010120960A (ja) * 2010-02-17 2010-06-03 Dainippon Printing Co Ltd 塩酸エピナスチンの製造方法
JP6006634B2 (ja) * 2011-12-28 2016-10-12 東和薬品株式会社 イソウレア化合物を用いるエピナスチンの製造方法
CN103172638B (zh) * 2013-03-13 2015-09-16 北京朗依制药有限公司 一种盐酸依匹斯汀的制备方法
CN104098575B (zh) * 2013-04-15 2016-06-01 四川科瑞德凯华制药有限公司 一种盐酸依匹斯汀晶型及其制备方法和用途
KR102041389B1 (ko) * 2017-12-12 2019-11-27 (주)프론트바이오 N-(9,13b-디하이드로-1H-디벤조[c,f]이미다조[1,5-a]아제핀-3-일)-2-하이드록시벤즈아미드 및 2-((9,13b-디하이드로-1H-디벤조[c,f]이미다조[1,5-a]아제핀-3-일) 카바모일)페닐 아세테이트의 화합물, 이의 제조방법 및 이를 포함하는 항염증 및 진통제 조성물
KR102080239B1 (ko) 2019-08-06 2020-02-21 한양대학교 에리카산학협력단 에피나스틴의 신규 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789410A (fr) * 1971-10-05 1973-01-15 Akzo Nv Nieuwe imidazolidine derivaten
NL7202963A (fr) * 1972-03-07 1973-09-11
NL7414038A (nl) * 1974-10-28 1976-05-03 Akzo Nv Nieuwe tetracyclische pyrrolidino derivaten.

Also Published As

Publication number Publication date
DD156708A5 (de) 1982-09-15
CS221288B2 (en) 1983-04-29
ES8301481A1 (es) 1982-12-01
ZA811500B (en) 1982-11-24
PT72631B (fr) 1982-12-30
FI810712L (fi) 1981-09-09
US4313931A (en) 1982-02-02
EP0035749B1 (fr) 1984-06-06
AU535359B2 (en) 1984-03-15
DK103581A (da) 1981-09-09
PL132141B1 (en) 1985-02-28
RO81652A (fr) 1983-04-29
IE810485L (en) 1981-09-08
IL62309A (en) 1984-06-29
DK154299C (da) 1989-03-28
HU180628B (en) 1983-03-28
SU1015829A3 (ru) 1983-04-30
PT72631A (fr) 1981-04-01
NO162073C (no) 1989-11-01
CA1150253A (fr) 1983-07-19
FI70898B (fi) 1986-07-18
GB2071095B (en) 1983-06-02
JPS56139484A (en) 1981-10-30
YU56881A (en) 1983-10-31
IL62309A0 (en) 1981-05-20
NO162073B (no) 1989-07-24
ES500150A0 (es) 1982-12-01
FI70898C (fi) 1986-10-27
JPH0366311B2 (fr) 1991-10-16
AU6815881A (en) 1981-09-17
HK63186A (en) 1986-09-05
DE3008944A1 (de) 1981-09-24
YU42557B (en) 1988-10-31
GR74805B (fr) 1984-07-12
IE51015B1 (en) 1986-09-03
UA8041A1 (uk) 1995-12-26
DE3163938D1 (en) 1984-07-12
EP0035749A1 (fr) 1981-09-16
CS410491A3 (en) 1992-05-13
PH15839A (en) 1983-04-08
NZ196446A (en) 1984-07-06
GB2071095A (en) 1981-09-16
RO81652B (ro) 1983-04-30
MX6869E (es) 1986-09-11
NO810762L (no) 1981-09-09
PL230036A1 (fr) 1982-05-24
DK154299B (da) 1988-10-31

Similar Documents

Publication Publication Date Title
BG33886A3 (en) Method for heterocyclic compounds producing
YU139281A (en) Process for preparing heterocyclic compounds
PT73503A (en) Process for preparing heterocyclic compounds
PT73913A (en) Method for producing chemical compounds
YU221681A (en) Process for obtaining n-arylbenzamide derivatives
YU43836B (en) Process for obtaining new pyridine compounds
YU144288A (en) Process for obtaining new substituted pyrimidins
YU227181A (en) Process for obtaining 3-aryl-5-isothiazole derivatives
BG37528A3 (en) Method for preparing 4- aminophenyl- aminophenyl- ammonium- tridecylphosphonate
BG35328A3 (en) Method for preparing imidodisulphamidic derivatives
BG35330A3 (en) Method for preparing 3- iodine- methylcephalosporines
DE3061645D1 (en) Method for preparing azolyl-vinyl-ketones
BG36348A3 (en) Method for preparing thienopyridinon derivatives
YU43720B (en) Process for producing substituted iminodiacids
YU171481A (en) Process for producing aryl-e-(heterocyclic)aryl sulfamates
KR850002011A (ko) 헤테로사이클릭 화합물의 제조방법
BG36935A3 (en) Method for preparing benzodiazepine compounds
YU81181A (en) Process for obtaining substituted derivatives
BG35897A3 (en) Method for preparing 5- (dihydroxy- phenoxy)- 1h- tetrazoles
BG36495A3 (en) Method for preparing 4- quinolic derivatives
BG35045A3 (en) Method for preparing substituted triarylthiazolic compounds
DE3160358D1 (en) Process for preparing aryl-phosphonyl compounds
BG36347A3 (en) Method for preparing thienopyridinon derivatives
BG35037A3 (en) Method for preparing phenylaminic derivatives
YU252981A (en) Process for obtaining 11-dodecene-1-yl derivatives