BG27903A3 - Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid - Google Patents

Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Info

Publication number
BG27903A3
BG27903A3 BG7428038A BG2803874A BG27903A3 BG 27903 A3 BG27903 A3 BG 27903A3 BG 7428038 A BG7428038 A BG 7428038A BG 2803874 A BG2803874 A BG 2803874A BG 27903 A3 BG27903 A3 BG 27903A3
Authority
BG
Bulgaria
Prior art keywords
furilmethil
morphinanes
benzomorphanes
methoxy
methyl
Prior art date
Application number
BG7428038A
Other languages
English (en)
Inventor
Merz
Langbein
Walther
Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of BG27903A3 publication Critical patent/BG27903A3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG7428038A 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid BG27903A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27903A3 true BG27903A3 (en) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG7428038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid
BG7428036A BG27901A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6-7- benzomorphanes and benzomorphinanes
BG7428037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG7428036A BG27901A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6-7- benzomorphanes and benzomorphinanes
BG7428037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Country Status (27)

Country Link
US (1) US3981874A (ja)
JP (1) JPS5738590B2 (ja)
AT (6) AT335633B (ja)
BE (1) BE821505A (ja)
BG (3) BG27903A3 (ja)
CA (1) CA1056377A (ja)
CH (6) CH609048A5 (ja)
CS (3) CS171195B2 (ja)
DD (1) DD115909A5 (ja)
DE (1) DE2354002A1 (ja)
DK (1) DK138325C (ja)
ES (6) ES431058A1 (ja)
FI (1) FI62079C (ja)
FR (1) FR2248838B1 (ja)
GB (1) GB1482552A (ja)
HU (1) HU176479B (ja)
IE (1) IE41528B1 (ja)
IL (1) IL45938A (ja)
NL (1) NL7413980A (ja)
NO (1) NO140859C (ja)
PH (1) PH11894A (ja)
PL (3) PL92053B1 (ja)
RO (5) RO65656A (ja)
SE (1) SE422791B (ja)
SU (6) SU511005A3 (ja)
YU (5) YU36519B (ja)
ZA (1) ZA746790B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) * 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2711757C (en) * 2008-02-12 2016-07-26 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166801B2 (ja) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
FR2248838A1 (ja) 1975-05-23
SE7413485L (ja) 1975-04-28
ES431059A1 (es) 1976-10-16
YU36949B (en) 1984-08-31
GB1482552A (en) 1977-08-10
CH609047A5 (ja) 1979-02-15
US3981874A (en) 1976-09-21
ATA828774A (de) 1976-07-15
CH609048A5 (ja) 1979-02-15
ES431055A1 (es) 1976-10-16
PL92053B1 (ja) 1977-03-31
DE2354002A1 (de) 1975-05-07
CA1056377A (en) 1979-06-12
ATA829074A (de) 1976-07-15
AT336202B (de) 1977-04-25
YU36951B (en) 1984-08-31
CH609686A5 (ja) 1979-03-15
DD115909A5 (ja) 1975-10-20
YU36952B (en) 1984-08-31
FI314174A (ja) 1975-04-28
SU508193A3 (ru) 1976-03-25
SU511005A3 (ru) 1976-04-15
DK138325C (da) 1979-01-22
AT335633B (de) 1977-03-25
JPS5071679A (ja) 1975-06-13
SE422791B (sv) 1982-03-29
YU285274A (en) 1982-02-25
YU285174A (en) 1982-06-18
RO65656A (ro) 1980-06-15
PL92052B1 (ja) 1977-03-31
ES431057A1 (es) 1976-10-16
FR2248838B1 (ja) 1977-11-04
IL45938A0 (en) 1974-12-31
HU176479B (en) 1981-03-28
CS171196B2 (ja) 1976-10-29
BG27901A3 (en) 1980-01-15
CS171194B2 (ja) 1976-10-29
ATA828574A (de) 1976-07-15
SU578870A3 (ru) 1977-10-30
AT335631B (de) 1977-03-25
IL45938A (en) 1977-12-30
ES431058A1 (es) 1976-10-16
IE41528B1 (en) 1980-01-30
BG27902A3 (en) 1980-01-15
ATA828874A (de) 1976-06-15
CH609340A5 (ja) 1979-02-28
PL92086B1 (ja) 1977-03-31
AT335076B (de) 1977-02-25
CH609046A5 (ja) 1979-02-15
ZA746790B (en) 1976-06-30
ES431054A1 (es) 1976-10-16
RO65658A (fr) 1979-07-15
NO140859C (no) 1979-11-28
YU285674A (en) 1982-06-18
RO65659A (ro) 1980-06-15
SU512707A3 (ru) 1976-04-30
NO140859B (no) 1979-08-20
JPS5738590B2 (ja) 1982-08-16
RO65655A (ro) 1980-06-15
YU36519B (en) 1984-02-29
SU508192A3 (ru) 1976-03-25
ATA828974A (de) 1976-08-15
NO743845L (ja) 1975-05-26
AT335634B (de) 1977-03-25
YU285474A (en) 1982-06-18
IE41528L (en) 1975-04-27
NL7413980A (nl) 1975-04-29
RO65657A (ro) 1980-06-15
DK138325B (da) 1978-08-14
YU285374A (en) 1982-06-18
FI62079B (fi) 1982-07-30
CS171195B2 (ja) 1976-10-29
YU36950B (en) 1984-08-31
DK559874A (ja) 1975-06-23
FI62079C (fi) 1982-11-10
SU510999A3 (ru) 1976-04-15
ATA828674A (de) 1976-07-15
CH609685A5 (ja) 1979-03-15
PH11894A (en) 1978-08-29
ES431056A1 (es) 1976-10-16
AT335632B (de) 1977-03-25
BE821505A (fr) 1975-04-25

Similar Documents

Publication Publication Date Title
BG27903A3 (en) Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid
BG24814A4 (en) Method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and salts thereof
CS222177B2 (en) Method of making the r-amino acids
BG27898A3 (en) Method of obtaining of 2-filamine-2-imidazoline derivatives and their salts
IL45294A (en) 7-acylamido-3-cephem-4-carboxylic acid derivatives and process for their preparation
GB1484606A (en) Substituted amino-benzoic acid derivatives and process for their manufacture
CH612926A5 (en) Process for the preparation of substituted alpha-aminooxy-carbohydrazide derivatives and their acid addition salts
IL38788A (en) N-(furylmethyl)-morphinanes,acid addition salts thereof and processes for their production
CS179371B2 (en) Method for preparation of new derivatives of dihydrolysergic acid and dihydroisolysergic acid.
IL45603A0 (en) 7-trichloroacetamido-3-desacetoxy-cephalosporanic acid derivatives and processes for their preparation
IL40197A0 (en) New derivatives of 17-hydroxy-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid and the corresponding gamma-lactones and their preparation
BG23745A3 (en) Method of obtaining n-(2-amino-3,5-dibrombenzyl)-n-methylcyclohexylamine
BG24663A3 (en) Method of preparing succinylsuccinic acid dieste s
IL43137A0 (en) Derivatives of glycyrhetinic acid and processes for the preparation thereof
PH11571A (en) P-gui-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2,its non-toxic salts and method of use thereof
EG11957A (en) Process for the preparation of otaconic acid and derivatives thereof
IL45602A0 (en) 6-trichloroacetamido-penicillanic acid derivatives and processes for their preparation
IL42820A0 (en) Novel derivatives of 6-amino-penicillanic acid and their preparation
ZA743116B (en) Method of preparing d1 tetramisole and acid addition salts thereof
ZA731818B (en) Derivatives of pyrazole-5-acetic acid and methods of preparing same
IL39097A0 (en) Pyrazolydinyl-phenylphosphoric acid derivatives,their salts and their preparation
ZA745657B (en) 7-monochloroacetamido-3-desacetoxycephalosporanic acid derivatives, their preparation and use
CS181169B2 (en) Method of preparing anilide of 2-methyl-5,6-dihydropyrane-3-carboxylic acid
CS182825B2 (en) Method for the production of novel derivatives of phenoxypropylamine and their salts
AU6947374A (en) METHOD OF PREPARING dl-TETRAMISOLE AND ACID ADDITION SALTS THEREOF