BG27902A3 - Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes - Google Patents

Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Info

Publication number
BG27902A3
BG27902A3 BG7428037A BG2803774A BG27902A3 BG 27902 A3 BG27902 A3 BG 27902A3 BG 7428037 A BG7428037 A BG 7428037A BG 2803774 A BG2803774 A BG 2803774A BG 27902 A3 BG27902 A3 BG 27902A3
Authority
BG
Bulgaria
Prior art keywords
furilmethil
morphinanes
benzomorphanes
methoxy
methyl
Prior art date
Application number
BG7428037A
Other languages
Bulgarian (bg)
English (en)
Inventor
Merz
Longbein
Walther
Stockhaus
Original Assignee
C.H. Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn,De filed Critical C.H. Boehringer Sohn,De
Publication of BG27902A3 publication Critical patent/BG27902A3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG7428037A 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes BG27902A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27902A3 true BG27902A3 (en) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG7428037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes
BG7428036A BG27901A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6-7- benzomorphanes and benzomorphinanes
BG7428038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG7428036A BG27901A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6-7- benzomorphanes and benzomorphinanes
BG7428038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Country Status (27)

Country Link
US (1) US3981874A (ja)
JP (1) JPS5738590B2 (ja)
AT (6) AT336202B (ja)
BE (1) BE821505A (ja)
BG (3) BG27902A3 (ja)
CA (1) CA1056377A (ja)
CH (6) CH609048A5 (ja)
CS (3) CS171195B2 (ja)
DD (1) DD115909A5 (ja)
DE (1) DE2354002A1 (ja)
DK (1) DK138325C (ja)
ES (6) ES431056A1 (ja)
FI (1) FI62079C (ja)
FR (1) FR2248838B1 (ja)
GB (1) GB1482552A (ja)
HU (1) HU176479B (ja)
IE (1) IE41528B1 (ja)
IL (1) IL45938A (ja)
NL (1) NL7413980A (ja)
NO (1) NO140859C (ja)
PH (1) PH11894A (ja)
PL (3) PL92053B1 (ja)
RO (5) RO65656A (ja)
SE (1) SE422791B (ja)
SU (6) SU510999A3 (ja)
YU (5) YU36952B (ja)
ZA (1) ZA746790B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
AR067673A1 (es) 2007-07-26 2009-10-21 Vitae Pharmaceuticals Inc Derivados de 1,3 oxazinan - 2 - ona como inhibidores ciclicos de la 11 beta -hidroxiesteroide deshidrogenasa 1. composiciones farmaceuticas.
AR069545A1 (es) * 2007-11-16 2010-02-03 Boehringer Ingelheim Pharma Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US20110028445A1 (en) * 2008-02-12 2011-02-03 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
ES2421537T3 (es) 2008-05-01 2013-09-03 Vitae Pharmaceuticals Inc Inhibidores cíclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071719A1 (es) 2008-05-13 2010-07-07 Boehringer Ingelheim Int Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PL2324018T3 (pl) 2008-07-25 2014-02-28 Boehringer Ingelheim Int Cykliczne inhibitory dehydrogenazy 11 beta-hydroksysteroidowej typu 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
UY33001A (es) * 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en) 2011-08-17 2014-06-25 Boehringer Ingelheim International GmbH Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166804B2 (ja) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
FR2248838A1 (ja) 1975-05-23
BG27901A3 (en) 1980-01-15
ATA828774A (de) 1976-07-15
AT335631B (de) 1977-03-25
PH11894A (en) 1978-08-29
IE41528L (en) 1975-04-27
YU36952B (en) 1984-08-31
CH609047A5 (ja) 1979-02-15
SU578870A3 (ru) 1977-10-30
RO65659A (ro) 1980-06-15
ES431059A1 (es) 1976-10-16
FI314174A (ja) 1975-04-28
CA1056377A (en) 1979-06-12
YU285174A (en) 1982-06-18
CH609686A5 (ja) 1979-03-15
DD115909A5 (ja) 1975-10-20
YU285474A (en) 1982-06-18
SU508193A3 (ru) 1976-03-25
IE41528B1 (en) 1980-01-30
AT335634B (de) 1977-03-25
RO65658A (fr) 1979-07-15
ATA828874A (de) 1976-06-15
YU36949B (en) 1984-08-31
GB1482552A (en) 1977-08-10
RO65657A (ro) 1980-06-15
SU508192A3 (ru) 1976-03-25
RO65655A (ro) 1980-06-15
ATA828574A (de) 1976-07-15
JPS5738590B2 (ja) 1982-08-16
NO140859C (no) 1979-11-28
ES431054A1 (es) 1976-10-16
RO65656A (ro) 1980-06-15
ES431056A1 (es) 1976-10-16
AT335633B (de) 1977-03-25
FI62079C (fi) 1982-11-10
HU176479B (en) 1981-03-28
BE821505A (fr) 1975-04-25
ATA829074A (de) 1976-07-15
BG27903A3 (en) 1980-01-15
IL45938A (en) 1977-12-30
YU36519B (en) 1984-02-29
SU511005A3 (ru) 1976-04-15
CS171196B2 (ja) 1976-10-29
FI62079B (fi) 1982-07-30
NO743845L (ja) 1975-05-26
CH609340A5 (ja) 1979-02-28
SU510999A3 (ru) 1976-04-15
JPS5071679A (ja) 1975-06-13
NO140859B (no) 1979-08-20
AT335076B (de) 1977-02-25
ES431058A1 (es) 1976-10-16
SE7413485L (ja) 1975-04-28
DE2354002A1 (de) 1975-05-07
SE422791B (sv) 1982-03-29
FR2248838B1 (ja) 1977-11-04
PL92053B1 (ja) 1977-03-31
CS171195B2 (ja) 1976-10-29
YU285374A (en) 1982-06-18
CH609048A5 (ja) 1979-02-15
ES431055A1 (es) 1976-10-16
PL92086B1 (ja) 1977-03-31
DK138325B (da) 1978-08-14
DK559874A (ja) 1975-06-23
ATA828674A (de) 1976-07-15
YU36950B (en) 1984-08-31
YU36951B (en) 1984-08-31
CH609685A5 (ja) 1979-03-15
IL45938A0 (en) 1974-12-31
SU512707A3 (ru) 1976-04-30
US3981874A (en) 1976-09-21
CH609046A5 (ja) 1979-02-15
YU285674A (en) 1982-06-18
PL92052B1 (ja) 1977-03-31
AT335632B (de) 1977-03-25
ES431057A1 (es) 1976-10-16
NL7413980A (nl) 1975-04-29
DK138325C (da) 1979-01-22
AT336202B (de) 1977-04-25
ATA828974A (de) 1976-08-15
CS171194B2 (ja) 1976-10-29
ZA746790B (en) 1976-06-30
YU285274A (en) 1982-02-25

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