BG27901A3 - Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи - Google Patents

Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи

Info

Publication number
BG27901A3
BG27901A3 BG028036A BG2803674A BG27901A3 BG 27901 A3 BG27901 A3 BG 27901A3 BG 028036 A BG028036 A BG 028036A BG 2803674 A BG2803674 A BG 2803674A BG 27901 A3 BG27901 A3 BG 27901A3
Authority
BG
Bulgaria
Prior art keywords
methyl
benzomorphanes
benzomorphinapes
furyl
methoxy
Prior art date
Application number
BG028036A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG27901A3 publication Critical patent/BG27901A3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG028036A 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи BG27901A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27901A3 true BG27901A3 (bg) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028037A BG27902A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани
BG028038A BG27903A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурилметил)-6,7-бензоморфани и морфипани и техните присъединителни с киселина соли

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG028037A BG27902A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фуриметил)-6,7-бензоморфани и морфипани
BG028038A BG27903A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурилметил)-6,7-бензоморфани и морфипани и техните присъединителни с киселина соли

Country Status (27)

Country Link
US (1) US3981874A (en, 2012)
JP (1) JPS5738590B2 (en, 2012)
AT (6) AT335634B (en, 2012)
BE (1) BE821505A (en, 2012)
BG (3) BG27901A3 (en, 2012)
CA (1) CA1056377A (en, 2012)
CH (6) CH609340A5 (en, 2012)
CS (3) CS171195B2 (en, 2012)
DD (1) DD115909A5 (en, 2012)
DE (1) DE2354002A1 (en, 2012)
DK (1) DK138325C (en, 2012)
ES (6) ES431054A1 (en, 2012)
FI (1) FI62079C (en, 2012)
FR (1) FR2248838B1 (en, 2012)
GB (1) GB1482552A (en, 2012)
HU (1) HU176479B (en, 2012)
IE (1) IE41528B1 (en, 2012)
IL (1) IL45938A (en, 2012)
NL (1) NL7413980A (en, 2012)
NO (1) NO140859C (en, 2012)
PH (1) PH11894A (en, 2012)
PL (3) PL92053B1 (en, 2012)
RO (5) RO65656A (en, 2012)
SE (1) SE422791B (en, 2012)
SU (6) SU510999A3 (en, 2012)
YU (5) YU36949B (en, 2012)
ZA (1) ZA746790B (en, 2012)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
TW200911796A (en) 2007-07-26 2009-03-16 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2220048B1 (en) 2007-11-16 2017-01-25 Boehringer Ingelheim International GmbH Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
ATE531696T1 (de) * 2008-02-12 2011-11-15 Boehringer Ingelheim Int Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001059A1 (es) 2008-05-01 2010-11-12 Boehringer Ingelheim Int Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras.
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5711115B2 (ja) 2008-05-13 2015-04-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリサイクリックカルボン酸誘導体、そのような化合物を含有する医薬及びその使用
ES2432150T3 (es) 2008-07-25 2013-12-02 Boehringer Ingelheim International Gmbh Inhibidores cíclicos de la 11 beta-hidroxiesteroide deshidrogenasa 1
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166803B2 (en, 2012) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
YU36952B (en) 1984-08-31
YU285374A (en) 1982-06-18
RO65655A (ro) 1980-06-15
SU511005A3 (ru) 1976-04-15
PL92053B1 (en, 2012) 1977-03-31
RO65658A (fr) 1979-07-15
ES431055A1 (es) 1976-10-16
FI314174A7 (en, 2012) 1975-04-28
CS171195B2 (en, 2012) 1976-10-29
YU36951B (en) 1984-08-31
YU285674A (en) 1982-06-18
DE2354002A1 (de) 1975-05-07
ATA828574A (de) 1976-07-15
JPS5738590B2 (en, 2012) 1982-08-16
SU508193A3 (ru) 1976-03-25
PH11894A (en) 1978-08-29
AT335631B (de) 1977-03-25
PL92052B1 (en, 2012) 1977-03-31
DK138325C (da) 1979-01-22
HU176479B (en) 1981-03-28
SU578870A3 (ru) 1977-10-30
SU512707A3 (ru) 1976-04-30
IE41528L (en) 1975-04-27
GB1482552A (en) 1977-08-10
CH609048A5 (en, 2012) 1979-02-15
IL45938A0 (en) 1974-12-31
FI62079B (fi) 1982-07-30
YU36950B (en) 1984-08-31
IL45938A (en) 1977-12-30
AT335632B (de) 1977-03-25
YU285474A (en) 1982-06-18
YU36519B (en) 1984-02-29
ES431056A1 (es) 1976-10-16
AT336202B (de) 1977-04-25
ES431058A1 (es) 1976-10-16
FR2248838B1 (en, 2012) 1977-11-04
CS171194B2 (en, 2012) 1976-10-29
CH609686A5 (en, 2012) 1979-03-15
ES431054A1 (es) 1976-10-16
BG27903A3 (bg) 1980-01-15
AT335076B (de) 1977-02-25
US3981874A (en) 1976-09-21
ATA828874A (de) 1976-06-15
IE41528B1 (en) 1980-01-30
SU508192A3 (ru) 1976-03-25
BE821505A (fr) 1975-04-25
ATA828974A (de) 1976-08-15
DD115909A5 (en, 2012) 1975-10-20
YU285274A (en) 1982-02-25
RO65656A (ro) 1980-06-15
ATA828774A (de) 1976-07-15
BG27902A3 (bg) 1980-01-15
YU36949B (en) 1984-08-31
RO65657A (ro) 1980-06-15
ATA828674A (de) 1976-07-15
CH609046A5 (en, 2012) 1979-02-15
PL92086B1 (en, 2012) 1977-03-31
DK138325B (da) 1978-08-14
ES431057A1 (es) 1976-10-16
FR2248838A1 (en, 2012) 1975-05-23
JPS5071679A (en, 2012) 1975-06-13
DK559874A (en, 2012) 1975-06-23
CS171196B2 (en, 2012) 1976-10-29
ATA829074A (de) 1976-07-15
NO743845L (en, 2012) 1975-05-26
CH609340A5 (en, 2012) 1979-02-28
ES431059A1 (es) 1976-10-16
AT335634B (de) 1977-03-25
ZA746790B (en) 1976-06-30
CH609047A5 (en, 2012) 1979-02-15
AT335633B (de) 1977-03-25
NO140859C (no) 1979-11-28
SE7413485L (en, 2012) 1975-04-28
CA1056377A (en) 1979-06-12
SU510999A3 (ru) 1976-04-15
NL7413980A (nl) 1975-04-29
SE422791B (sv) 1982-03-29
NO140859B (no) 1979-08-20
YU285174A (en) 1982-06-18
RO65659A (ro) 1980-06-15
CH609685A5 (en, 2012) 1979-03-15
FI62079C (fi) 1982-11-10

Similar Documents

Publication Publication Date Title
BG28065A4 (en) Method of obtaining of 2-phenyl-3-aroylbenzothiophenes
BG27901A3 (bg) Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG31497A3 (bg) Метод за получаване на 4-амино-5-алкил-сулфонил ортонизамиди
BG35189A3 (en) Method for preparing derivatives of 6- beta- hydroxyalkylpenicillanic acid
BG34338A3 (bg) Метод за получаване на тиадиазолилцефалоспорини
BG32717A3 (en) Method for obtaining of n- organo- n- phosphonomethylglicine- n- oxides
BG38333A3 (bg) Метод за получаване на заместени фенилкарбоксиоксими
BG31949A3 (en) Method for obtaining derivatives of phenyl- 2- indol
BG34453A3 (en) Method for obtaining penicilines and cephalosporines
BG27898A3 (en) Method of obtaining of 2-filamine-2-imidazoline derivatives and their salts
BG29573A3 (en) Method of obtaining of benzodiazepin derivatives
BG28072A4 (bg) Метод за получаване на 1 n заместени канамицинови производни
BG34036A3 (bg) Метод за получаване на пропаргил -2- фениламино- имидазолини-(2) и техните присъединителни с киселина соли
BG33275A3 (bg) Метод за получаване на бензофенони и техни производни
BG31070A3 (bg) Метод за получаване на 11-дезокси-16-арил-сигма- тетранорпростагландини
BG30778A3 (en) Method for obtaining of eburnamenine derivatives
BG34038A3 (bg) Метод за получаване на 7-заместени амино-ацетамидо оксадетиа-цефалоспорини
BG29572A3 (en) Method for obtaining of pyrazol salts
BG31073A3 (bg) Метод за получаване на 1,5-заместени-2-пиролидони
BG31503A3 (en) Method for obtaining the derivatives of octahjdroindolhinolzine
BG35466A3 (bg) Метод за получаване на производни на клавулановата киселина
BG28565A3 (bg) Метод за получаване на пиролхиноксалинони и пиролбензодиазепинони
BG30776A3 (en) Method for obtaining of eburnamenine derivatives
BG31229A3 (bg) Метод за получаване на n-(5-тетразолил)-1-оксо-1н-6-алкоксипиримидо(1,2-а)- хинолин-2-карбоксамиди
BG31947A3 (bg) Метод за получаване на ацетидинови производни