BG107101A - 2-фенилпиран-4-онови производни - Google Patents
2-фенилпиран-4-онови производни Download PDFInfo
- Publication number
- BG107101A BG107101A BG107101A BG10710102A BG107101A BG 107101 A BG107101 A BG 107101A BG 107101 A BG107101 A BG 107101A BG 10710102 A BG10710102 A BG 10710102A BG 107101 A BG107101 A BG 107101A
- Authority
- BG
- Bulgaria
- Prior art keywords
- group
- alkyl
- methanesulfonylphenyl
- formula
- pyran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200000637 | 2000-03-16 | ||
PCT/EP2001/003042 WO2001068633A1 (en) | 2000-03-16 | 2001-03-16 | 2-phenylpyran-4-one derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BG107101A true BG107101A (bg) | 2003-07-31 |
Family
ID=8492732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG107101A BG107101A (bg) | 2000-03-16 | 2002-09-13 | 2-фенилпиран-4-онови производни |
Country Status (27)
Country | Link |
---|---|
US (1) | US7354936B2 (cs) |
EP (1) | EP1263751B1 (cs) |
JP (1) | JP2003527389A (cs) |
KR (1) | KR20030005221A (cs) |
CN (1) | CN1429221A (cs) |
AR (1) | AR030410A1 (cs) |
AT (1) | ATE269316T1 (cs) |
AU (1) | AU2001254692A1 (cs) |
BG (1) | BG107101A (cs) |
BR (1) | BR0109252A (cs) |
CA (1) | CA2403149A1 (cs) |
CZ (1) | CZ20023058A3 (cs) |
DE (1) | DE60103859T2 (cs) |
EE (1) | EE200200528A (cs) |
ES (1) | ES2223830T3 (cs) |
HK (1) | HK1048117A1 (cs) |
HU (1) | HUP0301696A2 (cs) |
IL (1) | IL151598A0 (cs) |
MX (1) | MXPA02009016A (cs) |
NO (1) | NO20024393L (cs) |
NZ (1) | NZ521187A (cs) |
PE (1) | PE20011333A1 (cs) |
PL (1) | PL358062A1 (cs) |
RU (1) | RU2002127728A (cs) |
SK (1) | SK12832002A3 (cs) |
WO (1) | WO2001068633A1 (cs) |
ZA (1) | ZA200207184B (cs) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6465509B2 (en) * | 2000-06-30 | 2002-10-15 | Merck Frosst Canada & Co. | Pyrones as inhibitors of cyclooxygenase-2 |
ES2213485B1 (es) * | 2003-02-13 | 2005-12-16 | Almirall Prodesfarma, S.A. | Derivados de la 2-fenilpiran-4-ona. |
CN102731456B (zh) * | 2011-04-01 | 2014-07-09 | 华中科技大学 | 一种抗肿瘤化合物及其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH524614A (de) | 1969-12-31 | 1972-06-30 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Imidazolderivaten |
US3901908A (en) * | 1970-12-28 | 1975-08-26 | Ciba Geigy Corp | 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles |
US4304728A (en) * | 1979-04-05 | 1981-12-08 | Lilly Industries Limited | 6-Substituted pyranone compounds and their use as pharmaceuticals |
IL59748A (en) | 1979-04-05 | 1983-11-30 | Lilly Industries Ltd | 5-substituted pyranone derivatives,their production and pharmaceutical compositions containing them |
US6048850A (en) * | 1992-09-22 | 2000-04-11 | Young; Donald A. | Method of inhibiting prostaglandin synthesis in a human host |
EP0729466A1 (en) * | 1993-11-19 | 1996-09-04 | PARKE, DAVIS & COMPANY | Pyrone derivatives as protease inhibitors and antiviral agents |
US5521213A (en) | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
US5541204A (en) | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
CN1186492A (zh) | 1995-04-04 | 1998-07-01 | 葛兰素集团有限公司 | 咪唑并[1,2-α]吡啶衍生物 |
PT1043317E (pt) * | 1997-11-19 | 2009-05-11 | Kowa Co | Novos derivados de piridazina e fármacos que os contêm como ingrediente activo |
TW587079B (en) * | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
-
2001
- 2001-03-13 PE PE2001000241A patent/PE20011333A1/es not_active Application Discontinuation
- 2001-03-15 AR ARP010101221A patent/AR030410A1/es not_active Application Discontinuation
- 2001-03-16 IL IL15159801A patent/IL151598A0/xx unknown
- 2001-03-16 JP JP2001567725A patent/JP2003527389A/ja not_active Withdrawn
- 2001-03-16 AU AU2001254692A patent/AU2001254692A1/en not_active Abandoned
- 2001-03-16 EE EEP200200528A patent/EE200200528A/xx unknown
- 2001-03-16 CN CN01809447A patent/CN1429221A/zh active Pending
- 2001-03-16 NZ NZ521187A patent/NZ521187A/en unknown
- 2001-03-16 HU HU0301696A patent/HUP0301696A2/hu unknown
- 2001-03-16 DE DE60103859T patent/DE60103859T2/de not_active Expired - Lifetime
- 2001-03-16 KR KR1020027011875A patent/KR20030005221A/ko not_active Application Discontinuation
- 2001-03-16 RU RU2002127728/04A patent/RU2002127728A/ru not_active Application Discontinuation
- 2001-03-16 CZ CZ20023058A patent/CZ20023058A3/cs unknown
- 2001-03-16 EP EP01927742A patent/EP1263751B1/en not_active Expired - Lifetime
- 2001-03-16 SK SK1283-2002A patent/SK12832002A3/sk unknown
- 2001-03-16 WO PCT/EP2001/003042 patent/WO2001068633A1/en active IP Right Grant
- 2001-03-16 AT AT01927742T patent/ATE269316T1/de not_active IP Right Cessation
- 2001-03-16 PL PL01358062A patent/PL358062A1/xx not_active Application Discontinuation
- 2001-03-16 CA CA002403149A patent/CA2403149A1/en not_active Abandoned
- 2001-03-16 MX MXPA02009016A patent/MXPA02009016A/es unknown
- 2001-03-16 ES ES01927742T patent/ES2223830T3/es not_active Expired - Lifetime
- 2001-03-16 BR BR0109252-9A patent/BR0109252A/pt not_active IP Right Cessation
-
2002
- 2002-09-06 ZA ZA200207184A patent/ZA200207184B/en unknown
- 2002-09-13 BG BG107101A patent/BG107101A/bg unknown
- 2002-09-13 NO NO20024393A patent/NO20024393L/no not_active Application Discontinuation
- 2002-09-16 US US10/245,873 patent/US7354936B2/en not_active Expired - Fee Related
-
2003
- 2003-01-11 HK HK03100285.1A patent/HK1048117A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US7354936B2 (en) | 2008-04-08 |
BR0109252A (pt) | 2002-12-24 |
SK12832002A3 (sk) | 2003-11-04 |
ZA200207184B (en) | 2003-12-08 |
EP1263751B1 (en) | 2004-06-16 |
ATE269316T1 (de) | 2004-07-15 |
CZ20023058A3 (cs) | 2004-01-14 |
WO2001068633A1 (en) | 2001-09-20 |
KR20030005221A (ko) | 2003-01-17 |
PL358062A1 (en) | 2004-08-09 |
DE60103859T2 (de) | 2005-07-21 |
HK1048117A1 (zh) | 2003-03-21 |
JP2003527389A (ja) | 2003-09-16 |
IL151598A0 (en) | 2003-04-10 |
US20030232880A1 (en) | 2003-12-18 |
RU2002127728A (ru) | 2004-03-20 |
NO20024393D0 (no) | 2002-09-13 |
AU2001254692A1 (en) | 2001-09-24 |
NZ521187A (en) | 2004-03-26 |
NO20024393L (no) | 2002-11-13 |
EE200200528A (et) | 2004-04-15 |
EP1263751A1 (en) | 2002-12-11 |
CA2403149A1 (en) | 2001-09-20 |
AR030410A1 (es) | 2003-08-20 |
CN1429221A (zh) | 2003-07-09 |
HUP0301696A2 (hu) | 2003-09-29 |
PE20011333A1 (es) | 2002-01-16 |
DE60103859D1 (de) | 2004-07-22 |
MXPA02009016A (es) | 2004-10-15 |
ES2223830T3 (es) | 2005-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SU1650009A3 (ru) | Способ получени 5-арилалкил-4-алкокси-2(5Н)фуранонов | |
JP2001199954A (ja) | Cox−2インヒビターとしての(メチルスルホニル)フェニル−2−(5h)−フラノン類 | |
KR100378892B1 (ko) | 류코트리엔-길항활성을갖는벤조피란유도체 | |
KR100806684B1 (ko) | 2-페닐피란-4-온 유도체 | |
JPH09509159A (ja) | 炎症の治療のための置換スピロ化合物 | |
EP1263751B1 (en) | 2-phenylpyran-4-one derivatives | |
KR20000005146A (ko) | 퓨란 디아릴메틸리덴 유도체, 이의 제조방법 및이를 함유하는약제학적 조성물 | |
US20060189684A1 (en) | 3-Phenylfuran-2-one derivatives as cox-2 inhibitor | |
US5149834A (en) | 4-hydroxytetrahydropyran-2-one derivatives | |
PT87927B (pt) | Processo para a preparacao de acidos 3,5-dihidroxi-hepta-6-enoicos substituidos por 7-(1h-pirrol-3-ilo), das suas correspondentes delta-lactonas e sais, e de composicoes farmaceuticas que os contem | |
JPS606653A (ja) | 抗高コレステロ−ル血症活性を有する5−チアアルカン酸誘導体 | |
EP1592680B1 (en) | 2-phenylpyran-4-one derivatives as selective cox-2 inhibitors | |
US5843999A (en) | 2-phenylazulene derivatives and a manufacturing method of these compounds | |
KR101916106B1 (ko) | 2,5-다이아릴옥사졸 화합물 합성방법 및 이 화합물을 함유하는 항염증 약학 조성물 | |
EP1048649A1 (en) | 5-arylpyrrole derivatives |