BG105781A - Piperidine, tetrahydropyridine and piperazine derivatives, their preparartion and use - Google Patents
Piperidine, tetrahydropyridine and piperazine derivatives, their preparartion and useInfo
- Publication number
- BG105781A BG105781A BG105781A BG10578101A BG105781A BG 105781 A BG105781 A BG 105781A BG 105781 A BG105781 A BG 105781A BG 10578101 A BG10578101 A BG 10578101A BG 105781 A BG105781 A BG 105781A
- Authority
- BG
- Bulgaria
- Prior art keywords
- cr6r7
- piperidine
- disorders
- preparartion
- tetrahydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199900084 | 1999-01-22 | ||
PCT/DK2000/000026 WO2000043382A1 (fr) | 1999-01-22 | 2000-01-21 | Derives de piperidine, de tetrahydropyridine et de piperazine, leur preparation et leur utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105781A true BG105781A (en) | 2002-05-31 |
Family
ID=8089560
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105781A BG105781A (en) | 1999-01-22 | 2001-08-03 | Piperidine, tetrahydropyridine and piperazine derivatives, their preparartion and use |
Country Status (26)
Country | Link |
---|---|
US (2) | US6596722B2 (fr) |
EP (1) | EP1149087B1 (fr) |
JP (1) | JP2002535322A (fr) |
KR (1) | KR20010101606A (fr) |
CN (1) | CN1344265A (fr) |
AR (1) | AR022303A1 (fr) |
AT (1) | ATE263763T1 (fr) |
AU (1) | AU767377B2 (fr) |
BG (1) | BG105781A (fr) |
BR (1) | BR0009007A (fr) |
CA (1) | CA2361059A1 (fr) |
CZ (1) | CZ20012657A3 (fr) |
DE (1) | DE60009663T2 (fr) |
EA (1) | EA200100798A1 (fr) |
HK (1) | HK1045505A1 (fr) |
HU (1) | HUP0105065A3 (fr) |
IL (1) | IL144113A0 (fr) |
IS (1) | IS5983A (fr) |
MX (1) | MXPA01007226A (fr) |
NO (1) | NO20013538L (fr) |
NZ (1) | NZ512732A (fr) |
PL (1) | PL349909A1 (fr) |
SK (1) | SK10302001A3 (fr) |
TR (1) | TR200102089T2 (fr) |
WO (1) | WO2000043382A1 (fr) |
ZA (1) | ZA200105548B (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU736596B2 (en) * | 1997-07-25 | 2001-08-02 | H. Lundbeck A/S | Indole and 2,3-dihydroindole derivatives, their preparation and use |
IL148218A0 (en) * | 1999-08-23 | 2002-09-12 | Solvay Pharm Bv | New phenylpiperazines |
AR027133A1 (es) * | 1999-12-30 | 2003-03-12 | Lundbeck & Co As H | Derivados de heteroarilo, su preparacion y uso. |
DE60231507D1 (de) | 2001-07-20 | 2010-07-01 | Psychogenics Inc | Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten |
US7718802B2 (en) | 2001-08-10 | 2010-05-18 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
AU2002331064B2 (en) * | 2001-08-10 | 2007-08-23 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
US7655658B2 (en) | 2001-08-10 | 2010-02-02 | Palatin Technologies, Inc. | Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
US7354923B2 (en) * | 2001-08-10 | 2008-04-08 | Palatin Technologies, Inc. | Piperazine melanocortin-specific compounds |
US7732451B2 (en) | 2001-08-10 | 2010-06-08 | Palatin Technologies, Inc. | Naphthalene-containing melanocortin receptor-specific small molecule |
US7456184B2 (en) * | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
US7226755B1 (en) * | 2002-09-25 | 2007-06-05 | The Procter & Gamble Company | HPTPbeta as a target in treatment of angiogenesis mediated disorders |
US7507568B2 (en) * | 2002-09-25 | 2009-03-24 | The Proctor & Gamble Company | Three dimensional coordinates of HPTPbeta |
US7153858B2 (en) * | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
US7968548B2 (en) | 2003-05-01 | 2011-06-28 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine compounds with diamine groups |
US7727991B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific single acyl piperazine compounds |
US7727990B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine and keto-piperazine compounds |
US7235569B2 (en) | 2003-05-02 | 2007-06-26 | Wyeth | Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use |
US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
US7709484B1 (en) | 2004-04-19 | 2010-05-04 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
US7371769B2 (en) | 2004-12-07 | 2008-05-13 | Solvay Pharmaceuticals B.V. | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
US20060122175A1 (en) * | 2004-12-07 | 2006-06-08 | Solvay Pharmaceuticals B.V. | Benzdioxane piperazine derivatives with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
CA2587357A1 (fr) * | 2004-12-08 | 2006-06-15 | Solvay Pharmaceuticals B.V. | Derives de phenylpiperazine avec combinaison d'agonisme partiel de recepteurs de dopamine-d2 et inhibition de reabsorption de serotonine |
US20060122247A1 (en) | 2004-12-08 | 2006-06-08 | Solvay Pharmaceuticals B.V. | Aryloxyethylamine and phenylpiperazine derivatives with a combination of partial dopamine-D2 receptor agonism and serotonin reuptake inhibition |
DE102004063797A1 (de) * | 2004-12-30 | 2006-07-13 | Schwarz Pharma Ag | Sauerstoffhaltige annelierte Phenylpiperazin- und Phenyldiazepancarboxamide |
TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
KR100589877B1 (ko) * | 2005-12-20 | 2006-06-19 | 주식회사 픽슨이앤씨 | 파형강판 구조물의 보강라이너 설치용 거푸집 |
BRPI0710645A2 (pt) | 2006-04-07 | 2012-03-20 | The Procter & Gamble Company | Anticorpos que se ligam à proteína humana tirosina fosfatase beta (hptpbeta) e usos dos mesmos |
US8846685B2 (en) | 2006-06-27 | 2014-09-30 | Aerpio Therapeutics Inc. | Human protein tyrosine phosphatase inhibitors and methods of use |
US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
US7589212B2 (en) * | 2006-06-27 | 2009-09-15 | Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
US7795444B2 (en) * | 2006-06-27 | 2010-09-14 | Warner Chilcott Company | Human protein tyrosine phosphatase inhibitors and methods of use |
US7834017B2 (en) | 2006-08-11 | 2010-11-16 | Palatin Technologies, Inc. | Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents |
US9096555B2 (en) | 2009-01-12 | 2015-08-04 | Aerpio Therapeutics, Inc. | Methods for treating vascular leak syndrome |
US8367676B2 (en) | 2009-06-30 | 2013-02-05 | Astrazeneca Ab | 2-carboxamide-7-piperazinyl-benzofuran derivatives 774 |
MY160399A (en) | 2009-07-06 | 2017-03-15 | Aerpio Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
RU2013131161A (ru) | 2010-12-20 | 2015-01-27 | Астразенека Аб | Производное 2-карбоксамид-4-пиперазинил-бензофурана |
WO2013056240A1 (fr) | 2011-10-13 | 2013-04-18 | Aerpio Therapeutics, Inc. | Méthodes de traitement du syndrome de fuite vasculaire et du cancer |
EP3027607B1 (fr) | 2013-07-29 | 2020-08-26 | Sunshine Lake Pharma Co., Ltd. | Composés hétéroaryliques substitués et procédés d'utilisation |
CN104725363B (zh) * | 2013-12-20 | 2019-03-01 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
CN106243088B (zh) * | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
US10934279B2 (en) | 2018-06-13 | 2021-03-02 | Pfizer Inc. | GLP-1 receptor agonists and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
FR2670491B1 (fr) * | 1990-12-14 | 1993-02-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
IT1251144B (it) * | 1991-07-30 | 1995-05-04 | Boehringer Ingelheim Italia | Derivati del benzimidazolone |
FR2692264B1 (fr) * | 1992-06-12 | 1994-08-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant. |
DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
RU2124511C1 (ru) * | 1993-05-14 | 1999-01-10 | Фармасьютикал Ко., Лтд | Производные пиперазина |
RU2118322C1 (ru) * | 1993-07-05 | 1998-08-27 | Дюфар Интернэшнл Рисерч Б.В. | 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли |
-
2000
- 2000-01-17 AR ARP000100197A patent/AR022303A1/es not_active Application Discontinuation
- 2000-01-21 MX MXPA01007226A patent/MXPA01007226A/es not_active Application Discontinuation
- 2000-01-21 WO PCT/DK2000/000026 patent/WO2000043382A1/fr not_active Application Discontinuation
- 2000-01-21 CA CA002361059A patent/CA2361059A1/fr not_active Abandoned
- 2000-01-21 SK SK1030-2001A patent/SK10302001A3/sk unknown
- 2000-01-21 AU AU22781/00A patent/AU767377B2/en not_active Ceased
- 2000-01-21 EA EA200100798A patent/EA200100798A1/ru unknown
- 2000-01-21 EP EP00901481A patent/EP1149087B1/fr not_active Expired - Lifetime
- 2000-01-21 AT AT00901481T patent/ATE263763T1/de not_active IP Right Cessation
- 2000-01-21 JP JP2000594798A patent/JP2002535322A/ja not_active Withdrawn
- 2000-01-21 IL IL14411300A patent/IL144113A0/xx unknown
- 2000-01-21 NZ NZ512732A patent/NZ512732A/en unknown
- 2000-01-21 CZ CZ20012657A patent/CZ20012657A3/cs unknown
- 2000-01-21 BR BR0009007-7A patent/BR0009007A/pt not_active IP Right Cessation
- 2000-01-21 CN CN00805148A patent/CN1344265A/zh active Pending
- 2000-01-21 DE DE60009663T patent/DE60009663T2/de not_active Expired - Fee Related
- 2000-01-21 HU HU0105065A patent/HUP0105065A3/hu unknown
- 2000-01-21 KR KR1020017009122A patent/KR20010101606A/ko not_active Application Discontinuation
- 2000-01-21 TR TR2001/02089T patent/TR200102089T2/xx unknown
- 2000-01-21 PL PL00349909A patent/PL349909A1/xx not_active Application Discontinuation
-
2001
- 2001-06-28 IS IS5983A patent/IS5983A/is unknown
- 2001-07-05 ZA ZA200105548A patent/ZA200105548B/en unknown
- 2001-07-09 US US09/901,585 patent/US6596722B2/en not_active Expired - Fee Related
- 2001-07-17 NO NO20013538A patent/NO20013538L/no not_active Application Discontinuation
- 2001-08-03 BG BG105781A patent/BG105781A/xx unknown
-
2002
- 2002-05-16 US US10/147,950 patent/US20020173512A1/en not_active Abandoned
- 2002-09-20 HK HK02106884.4A patent/HK1045505A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU2278100A (en) | 2000-08-07 |
ATE263763T1 (de) | 2004-04-15 |
ZA200105548B (en) | 2002-07-05 |
AR022303A1 (es) | 2002-09-04 |
CN1344265A (zh) | 2002-04-10 |
MXPA01007226A (es) | 2002-04-24 |
BR0009007A (pt) | 2001-11-27 |
DE60009663T2 (de) | 2005-04-14 |
WO2000043382A1 (fr) | 2000-07-27 |
NZ512732A (en) | 2003-10-31 |
DE60009663D1 (de) | 2004-05-13 |
US20020173512A1 (en) | 2002-11-21 |
IS5983A (is) | 2001-06-28 |
US20020035113A1 (en) | 2002-03-21 |
AU767377B2 (en) | 2003-11-06 |
EP1149087A1 (fr) | 2001-10-31 |
SK10302001A3 (sk) | 2002-01-07 |
JP2002535322A (ja) | 2002-10-22 |
HUP0105065A2 (hu) | 2002-07-29 |
HUP0105065A3 (en) | 2003-06-30 |
EP1149087B1 (fr) | 2004-04-07 |
CZ20012657A3 (cs) | 2002-02-13 |
NO20013538L (no) | 2001-09-17 |
TR200102089T2 (tr) | 2002-07-22 |
KR20010101606A (ko) | 2001-11-14 |
US6596722B2 (en) | 2003-07-22 |
EA200100798A1 (ru) | 2001-12-24 |
HK1045505A1 (zh) | 2002-11-29 |
NO20013538D0 (no) | 2001-07-17 |
PL349909A1 (en) | 2002-10-07 |
IL144113A0 (en) | 2002-05-23 |
CA2361059A1 (fr) | 2000-07-27 |
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