BG104786A - Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines - Google Patents
Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalinesInfo
- Publication number
- BG104786A BG104786A BG104786A BG10478600A BG104786A BG 104786 A BG104786 A BG 104786A BG 104786 A BG104786 A BG 104786A BG 10478600 A BG10478600 A BG 10478600A BG 104786 A BG104786 A BG 104786A
- Authority
- BG
- Bulgaria
- Prior art keywords
- linkage
- ny4y5
- alkyl
- compounds
- ny1y2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9828417.7A GB9828417D0 (en) | 1998-12-23 | 1998-12-23 | Chemical compounds |
US12608499P | 1999-03-25 | 1999-03-25 | |
PCT/GB1999/004430 WO2000039103A1 (en) | 1998-12-23 | 1999-12-23 | Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines |
Publications (1)
Publication Number | Publication Date |
---|---|
BG104786A true BG104786A (en) | 2001-04-30 |
Family
ID=26314897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104786A BG104786A (en) | 1998-12-23 | 2000-09-20 | Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines |
Country Status (10)
Country | Link |
---|---|
US (1) | US6632814B1 (xx) |
EP (1) | EP1056728B1 (xx) |
AP (1) | AP2000001924A0 (xx) |
AU (1) | AU1881900A (xx) |
BG (1) | BG104786A (xx) |
DE (1) | DE69937603T2 (xx) |
ES (1) | ES2297943T3 (xx) |
HU (1) | HUP0200481A3 (xx) |
SK (1) | SK14192000A3 (xx) |
WO (1) | WO2000039103A1 (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2370805C (en) * | 1999-05-05 | 2012-07-03 | Aventis Pharma Limited | Ureas as cell adhesion modulators |
US6750215B2 (en) | 2001-08-08 | 2004-06-15 | Pharmacia & Upjohn, S.P.A. | Substituted benzoxazines as integrin antagonists |
US6794385B2 (en) | 2001-08-08 | 2004-09-21 | Pharmacia & Upjohn, S.P.A. | Benzoxazine derivatives useful as integrin receptor antagonists |
NZ607928A (en) * | 2010-10-18 | 2014-03-28 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
PL2794600T3 (pl) | 2011-12-22 | 2018-06-29 | Novartis Ag | Pochodne 2,3-dihydro-benzo[1,4]oksazyny i powiązane związki jako inhibitory kinazy fosfoinozytydu-3 (PI3K) do leczenia np. reumatoidalnego zapalenia stawów |
CN103275021B (zh) * | 2013-05-24 | 2015-05-20 | 东北农业大学 | N-二氯乙酰基-6,7-二氯-1,2,3,4-四氢喹喔啉及其制备方法 |
MX370535B (es) | 2013-11-18 | 2019-12-17 | Forma Therapeutics Inc | Compuestos de tetrahidroquinolina como inhibidores del bromodominio extra terminal y bromo (bet) y el uso de los mismos en el tratamiento de cáncer. |
CN106029076B (zh) | 2013-11-18 | 2019-06-07 | 福马疗法公司 | 作为bet溴域抑制剂的苯并哌嗪组合物 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS588016A (ja) | 1981-07-06 | 1983-01-18 | Mitsubishi Chem Ind Ltd | 強心剤 |
DE3338846A1 (de) | 1982-10-29 | 1984-05-03 | Toyama Chemical Co. Ltd., Tokyo | Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben |
US4582909A (en) | 1984-02-02 | 1986-04-15 | Warner-Lambert Company | Benzobicyclic lactam acids and derivatives as cognition activators |
AU626881B2 (en) | 1988-07-14 | 1992-08-13 | F. Hoffmann-La Roche Ag | Benzofused heterocyclics used as pharmaceuticals |
ES2014560A6 (es) | 1988-12-30 | 1990-07-16 | Marga Investigacion | Proceso para la preparacion de un nuevo reactivo organo-sililpolifosforico y su aplicacion al proceso de sontesis de 3-carboxi-quinolonas o azaquinolonas y sus sales. |
EP0407137B1 (en) * | 1989-07-03 | 1996-05-01 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzazine compounds and pharmaceutical uses thereof |
GB9320277D0 (en) | 1993-10-01 | 1993-11-17 | Nycomed Salutar Inc | Chelants |
DK0509398T3 (da) | 1991-04-15 | 2002-01-14 | Aventis Pharma Gmbh | Quinoxaliner, fremgangsmåder til deres fremstilling samt deres anvendelse |
AU1493092A (en) * | 1991-04-18 | 1992-10-22 | Ortho Pharmaceutical Corporation | (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones |
TW301607B (xx) * | 1993-03-09 | 1997-04-01 | Takeda Pharm Industry Co Ltd | |
WO1994020473A1 (en) | 1993-03-11 | 1994-09-15 | Yamanouchi Pharmaceutical Co., Ltd. | Compound with vasopressin antagonism |
US5334598A (en) | 1993-03-19 | 1994-08-02 | Merck & Co., Inc. | Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives |
WO1995015973A1 (en) * | 1993-12-06 | 1995-06-15 | Cytel Corporation | Cs-1 peptidomimetics, compositions and methods of using the same |
EP0757687A1 (en) | 1994-04-23 | 1997-02-12 | Smithkline Beecham Plc | Tricyclic derivatives as 5ht 2c? and 5ht 2b? antagonists |
EP0774462A4 (en) | 1994-08-03 | 1997-10-29 | Fujisawa Pharmaceutical Co | HETEROCYCLIC COMPOUND |
CA2203659A1 (en) | 1994-10-27 | 1996-05-09 | Teruo Oku | Pyridopyrimidones, quinolines and fused n-heterocycles as bradykinin antagonists |
US5977125A (en) | 1994-10-31 | 1999-11-02 | Eisai Co., Ltd. | Mono-or polyenic carboxylic acid derivatives |
US6248713B1 (en) * | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
GB9605883D0 (en) | 1996-03-20 | 1996-05-22 | Smithkline Beecham Plc | Novel compounds |
ATE204857T1 (de) * | 1996-03-29 | 2001-09-15 | Searle & Co | Meta-substituierte phenylenderivate und ihre verwendung als alphavbeta3 intergrin-antagonisten oder inhibitoren |
JPH10158192A (ja) | 1996-10-03 | 1998-06-16 | Eisai Co Ltd | 移植片対宿主疾患(gvhd)の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物 |
DE19647381A1 (de) * | 1996-11-15 | 1998-05-20 | Hoechst Ag | Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten |
WO1999020309A1 (fr) | 1997-10-22 | 1999-04-29 | Eisai Co., Ltd. | Agonistes de l'acide retinoique, agents preventifs et therapeutiques des nephrites |
EP1027328B1 (en) * | 1997-10-31 | 2006-08-23 | Aventis Pharma Limited | Substituted anilides |
EP1042279B1 (en) * | 1997-12-23 | 2005-03-02 | Aventis Pharma Limited | Substituted beta-alanines |
WO1999054321A1 (en) * | 1998-04-21 | 1999-10-28 | Aventis Pharma Limited | Substituted diamines and their use as cell adhesion inhibitors |
-
1999
- 1999-12-23 AU AU18819/00A patent/AU1881900A/en not_active Abandoned
- 1999-12-23 SK SK1419-2000A patent/SK14192000A3/sk unknown
- 1999-12-23 DE DE69937603T patent/DE69937603T2/de not_active Expired - Lifetime
- 1999-12-23 AP APAP/P/2000/001924A patent/AP2000001924A0/en unknown
- 1999-12-23 ES ES99962463T patent/ES2297943T3/es not_active Expired - Lifetime
- 1999-12-23 WO PCT/GB1999/004430 patent/WO2000039103A1/en active IP Right Grant
- 1999-12-23 HU HU0200481A patent/HUP0200481A3/hu unknown
- 1999-12-23 EP EP99962463A patent/EP1056728B1/en not_active Expired - Lifetime
-
2000
- 2000-08-23 US US09/644,308 patent/US6632814B1/en not_active Expired - Fee Related
- 2000-09-20 BG BG104786A patent/BG104786A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ES2297943T3 (es) | 2008-05-01 |
HUP0200481A3 (en) | 2002-12-28 |
WO2000039103B1 (en) | 2000-09-28 |
HUP0200481A2 (en) | 2002-06-29 |
WO2000039103A1 (en) | 2000-07-06 |
SK14192000A3 (sk) | 2001-07-10 |
DE69937603D1 (de) | 2008-01-03 |
AU1881900A (en) | 2000-07-31 |
DE69937603T2 (de) | 2008-10-23 |
AP2000001924A0 (en) | 2000-09-30 |
EP1056728B1 (en) | 2007-11-21 |
US6632814B1 (en) | 2003-10-14 |
EP1056728A1 (en) | 2000-12-06 |
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