HUP0200481A3 - Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines, process for their preparation and pharmaceutical compositions containing them - Google Patents

Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP0200481A3
HUP0200481A3 HU0200481A HUP0200481A HUP0200481A3 HU P0200481 A3 HUP0200481 A3 HU P0200481A3 HU 0200481 A HU0200481 A HU 0200481A HU P0200481 A HUP0200481 A HU P0200481A HU P0200481 A3 HUP0200481 A3 HU P0200481A3
Authority
HU
Hungary
Prior art keywords
tetrahydroquinoxalines
oxazines
benzo
dihydro
preparation
Prior art date
Application number
HU0200481A
Other languages
English (en)
Original Assignee
Aventis Pharma Ltd West Mallin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828417.7A external-priority patent/GB9828417D0/en
Application filed by Aventis Pharma Ltd West Mallin filed Critical Aventis Pharma Ltd West Mallin
Publication of HUP0200481A2 publication Critical patent/HUP0200481A2/hu
Publication of HUP0200481A3 publication Critical patent/HUP0200481A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU0200481A 1998-12-23 1999-12-23 Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines, process for their preparation and pharmaceutical compositions containing them HUP0200481A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828417.7A GB9828417D0 (en) 1998-12-23 1998-12-23 Chemical compounds
US12608499P 1999-03-25 1999-03-25

Publications (2)

Publication Number Publication Date
HUP0200481A2 HUP0200481A2 (en) 2002-06-29
HUP0200481A3 true HUP0200481A3 (en) 2002-12-28

Family

ID=26314897

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200481A HUP0200481A3 (en) 1998-12-23 1999-12-23 Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines, process for their preparation and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US6632814B1 (hu)
EP (1) EP1056728B1 (hu)
AP (1) AP2000001924A0 (hu)
AU (1) AU1881900A (hu)
BG (1) BG104786A (hu)
DE (1) DE69937603T2 (hu)
ES (1) ES2297943T3 (hu)
HU (1) HUP0200481A3 (hu)
SK (1) SK14192000A3 (hu)
WO (1) WO2000039103A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068223A1 (en) * 1999-05-05 2000-11-16 Aventis Pharma Limited Ureas and their use as cell adhesion modulators
US6794385B2 (en) 2001-08-08 2004-09-21 Pharmacia & Upjohn, S.P.A. Benzoxazine derivatives useful as integrin receptor antagonists
US6750215B2 (en) 2001-08-08 2004-06-15 Pharmacia & Upjohn, S.P.A. Substituted benzoxazines as integrin antagonists
US8349833B2 (en) 2010-10-18 2013-01-08 Cerenis Therapeutics Holding Sa Compounds, compositions and methods useful for cholesterol mobilisation
KR101656592B1 (ko) 2011-12-22 2016-09-23 노파르티스 아게 디히드로-벤조-옥사진 및 디히드로-피리도-옥사진 유도체
CN103275021B (zh) * 2013-05-24 2015-05-20 东北农业大学 N-二氯乙酰基-6,7-二氯-1,2,3,4-四氢喹喔啉及其制备方法
AU2014348191B2 (en) 2013-11-18 2019-03-28 Forma Therapeutics Inc. Tetrahydroquinoline compositions as BET bromodomain inhibitors
RU2720237C2 (ru) 2013-11-18 2020-04-28 Форма Терапеутикс, Инк. Композиции, содержащие бензопиперазин, в качестве ингибиторов бромодоменов вет

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588016A (ja) 1981-07-06 1983-01-18 Mitsubishi Chem Ind Ltd 強心剤
DE3338846A1 (de) 1982-10-29 1984-05-03 Toyama Chemical Co. Ltd., Tokyo Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben
US4582909A (en) 1984-02-02 1986-04-15 Warner-Lambert Company Benzobicyclic lactam acids and derivatives as cognition activators
AU626881B2 (en) 1988-07-14 1992-08-13 F. Hoffmann-La Roche Ag Benzofused heterocyclics used as pharmaceuticals
ES2014560A6 (es) 1988-12-30 1990-07-16 Marga Investigacion Proceso para la preparacion de un nuevo reactivo organo-sililpolifosforico y su aplicacion al proceso de sontesis de 3-carboxi-quinolonas o azaquinolonas y sus sales.
EP0407137B1 (en) * 1989-07-03 1996-05-01 Yoshitomi Pharmaceutical Industries, Ltd. Benzazine compounds and pharmaceutical uses thereof
GB9320277D0 (en) 1993-10-01 1993-11-17 Nycomed Salutar Inc Chelants
DE59209965D1 (de) 1991-04-15 2002-10-17 Aventis Pharma Gmbh Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung
AU1493092A (en) * 1991-04-18 1992-10-22 Ortho Pharmaceutical Corporation (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones
TW301607B (hu) * 1993-03-09 1997-04-01 Takeda Pharm Industry Co Ltd
WO1994020473A1 (en) 1993-03-11 1994-09-15 Yamanouchi Pharmaceutical Co., Ltd. Compound with vasopressin antagonism
US5334598A (en) 1993-03-19 1994-08-02 Merck & Co., Inc. Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives
AU693143B2 (en) * 1993-12-06 1998-06-25 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
WO1995029177A1 (en) 1994-04-23 1995-11-02 Smithkline Beecham P.L.C. Tricyclic derivatives as 5ht2c and 5ht2b antagonists
US6083961A (en) 1994-08-03 2000-07-04 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole compounds as bradykinin antagonists
CN1168667A (zh) 1994-10-27 1997-12-24 藤沢药品工业株式会社 用作缓激肽拮抗剂的吡啶并嘧啶酮，喹啉和稠合的n-杂环化合物
US5977125A (en) 1994-10-31 1999-11-02 Eisai Co., Ltd. Mono-or polyenic carboxylic acid derivatives
US6248713B1 (en) * 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
GB9605883D0 (en) 1996-03-20 1996-05-22 Smithkline Beecham Plc Novel compounds
AU2337097A (en) * 1996-03-29 1997-10-22 G.D. Searle & Co. Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors
JPH10158192A (ja) 1996-10-03 1998-06-16 Eisai Co Ltd 移植片対宿主疾患（ｇｖｈｄ）の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物
DE19647381A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
CA2307613A1 (en) 1997-10-22 1999-04-29 Eisai Co., Ltd. Retinoic acid agonist as a prophylactic and therapeutic agent for nephritis
CA2303848C (en) * 1997-10-31 2008-09-30 Rhone-Poulenc Rorer Limited Substituted anilides
JP4555469B2 (ja) * 1997-12-23 2010-09-29 アベンテイス・フアルマ・リミテツド 置換されたβ−アラニン
WO1999054321A1 (en) * 1998-04-21 1999-10-28 Aventis Pharma Limited Substituted diamines and their use as cell adhesion inhibitors

Also Published As

Publication number Publication date
EP1056728B1 (en) 2007-11-21
HUP0200481A2 (en) 2002-06-29
BG104786A (en) 2001-04-30
AU1881900A (en) 2000-07-31
ES2297943T3 (es) 2008-05-01
DE69937603T2 (de) 2008-10-23
SK14192000A3 (sk) 2001-07-10
DE69937603D1 (de) 2008-01-03
WO2000039103B1 (en) 2000-09-28
US6632814B1 (en) 2003-10-14
AP2000001924A0 (en) 2000-09-30
EP1056728A1 (en) 2000-12-06
WO2000039103A1 (en) 2000-07-06

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