BG103417A - Condensed pyrimidine bicyclic derivatives - Google Patents
Condensed pyrimidine bicyclic derivativesInfo
- Publication number
- BG103417A BG103417A BG103417A BG10341799A BG103417A BG 103417 A BG103417 A BG 103417A BG 103417 A BG103417 A BG 103417A BG 10341799 A BG10341799 A BG 10341799A BG 103417 A BG103417 A BG 103417A
- Authority
- BG
- Bulgaria
- Prior art keywords
- bicyclic derivatives
- condensed pyrimidine
- pyrimidine bicyclic
- compounds
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3186296P | 1996-11-27 | 1996-11-27 | |
US4184697P | 1997-04-09 | 1997-04-09 | |
PCT/IB1997/001393 WO1998023613A1 (fr) | 1996-11-27 | 1997-11-05 | Derives de pyrimidines bicycliques fusionnes |
Publications (1)
Publication Number | Publication Date |
---|---|
BG103417A true BG103417A (en) | 2000-06-30 |
Family
ID=26707706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG103417A BG103417A (en) | 1996-11-27 | 1999-05-20 | Condensed pyrimidine bicyclic derivatives |
Country Status (24)
Country | Link |
---|---|
US (1) | US6413971B1 (fr) |
EP (1) | EP0946554A1 (fr) |
JP (1) | JP2000505109A (fr) |
KR (1) | KR20000057228A (fr) |
CN (1) | CN1237177A (fr) |
AP (1) | AP9701146A0 (fr) |
AR (1) | AR010740A1 (fr) |
AU (1) | AU4718997A (fr) |
BG (1) | BG103417A (fr) |
BR (1) | BR9713552A (fr) |
CA (1) | CA2272705C (fr) |
CO (1) | CO4650037A1 (fr) |
HN (1) | HN1997000146A (fr) |
HR (1) | HRP970641A2 (fr) |
ID (1) | ID18958A (fr) |
IL (1) | IL129825A0 (fr) |
IS (1) | IS5041A (fr) |
MA (1) | MA26452A1 (fr) |
NO (1) | NO992524D0 (fr) |
OA (1) | OA11051A (fr) |
PA (1) | PA8442001A1 (fr) |
PE (1) | PE17299A1 (fr) |
TN (1) | TNSN97192A1 (fr) |
WO (1) | WO1998023613A1 (fr) |
Families Citing this family (91)
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JP4275733B2 (ja) * | 1996-01-23 | 2009-06-10 | ノバルティス アクチエンゲゼルシャフト | ピロロピリミジンおよびその製造法 |
BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
KR100489174B1 (ko) | 1996-03-05 | 2005-09-30 | 제네카-파마 소시에떼아노님 | 4-아닐리노퀴나졸린유도체 |
GB9707800D0 (en) | 1996-05-06 | 1997-06-04 | Zeneca Ltd | Chemical compounds |
HRP970371A2 (en) * | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
KR100567649B1 (ko) | 1996-09-25 | 2006-04-05 | 아스트라제네카 유케이 리미티드 | 혈관 내피 성장 인자와 같은 성장 인자의 효과를 억제하는 퀴놀린 유도체 |
GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
ZA986729B (en) * | 1997-07-29 | 1999-02-02 | Warner Lambert Co | Irreversible inhibitors of tyrosine kinases |
EP1005470B1 (fr) | 1997-08-22 | 2007-08-01 | AstraZeneca AB | Derives d'oxindolylquinazoline utiles comme inhibiteurs d'angiogenese |
AU3951899A (en) * | 1998-06-19 | 2000-01-05 | Pfizer Products Inc. | Pyrrolo(2,3-d)pyrimidine compounds |
PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
EP1226136B1 (fr) | 1999-10-19 | 2004-12-29 | Merck & Co., Inc. | Inhibiteurs de tyrosine kinases |
US6794393B1 (en) | 1999-10-19 | 2004-09-21 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
EP1676845B1 (fr) | 1999-11-05 | 2008-06-11 | AstraZeneca AB | Nouveaux dérivés de type quinazoline |
JP4078074B2 (ja) | 1999-12-10 | 2008-04-23 | ファイザー・プロダクツ・インク | ピロロ[2,3−d]ピリミジン化合物 |
ES2245955T3 (es) | 1999-12-21 | 2006-02-01 | Sugen, Inc. | 7-aza-indolin-2-onas 4-sustituidas y su utilizacion como inhibidores de proteina-quinasa. |
US6420382B2 (en) | 2000-02-25 | 2002-07-16 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
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US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
ES2223827T3 (es) | 2000-06-06 | 2005-03-01 | Pfizer Products Inc. | Derivados de tiofeno utiles como agentes anticancerigenos. |
CN100351253C (zh) | 2000-06-26 | 2007-11-28 | 辉瑞产品公司 | 作为免疫抑制剂的吡咯并[2,3-d]嘧啶化合物 |
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DE60134679D1 (de) | 2000-10-20 | 2008-08-14 | Eisai R&D Man Co Ltd | Stickstoff enthaltende aromatische Heterozyklen |
ES2372028T3 (es) | 2000-10-23 | 2012-01-13 | Glaxosmithkline Llc | Nuevo compuesto de 8h-pirido[2,3-d]pirimidin-7-ona trisustituida para el tratamiento de enfermedades mediadas por la csbp/p38 quinasa. |
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US7541367B2 (en) * | 2005-05-31 | 2009-06-02 | Janssen Pharmaceutica, N.V. | 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders |
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US9139590B2 (en) | 2011-02-04 | 2015-09-22 | Duquesne University Of The Holy Spirit | Bicyclic and tricyclic pyrimidine tyrosine kinase inhibitors with antitubulin activity and methods of treating a patient |
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KR102204279B1 (ko) | 2013-05-14 | 2021-01-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 자궁내막암 대상의 렌바티닙 화합물에 대한 반응성을 예측 및 평가하기 위한 생체표지 |
JP6487921B2 (ja) | 2013-12-17 | 2019-03-20 | ファイザー・インク | LRRK2阻害薬としての新規の3,4−二置換−1H−ピロロ[2,3−b]ピリジンおよび4,5−二置換−7H−ピロロ[2,3−c]ピリダジン |
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1997
- 1997-11-05 CA CA002272705A patent/CA2272705C/fr not_active Expired - Fee Related
- 1997-11-05 KR KR1019990704587A patent/KR20000057228A/ko not_active Application Discontinuation
- 1997-11-05 EP EP97909525A patent/EP0946554A1/fr not_active Ceased
- 1997-11-05 CN CN97199662A patent/CN1237177A/zh active Pending
- 1997-11-05 BR BR9713552-6A patent/BR9713552A/pt unknown
- 1997-11-05 WO PCT/IB1997/001393 patent/WO1998023613A1/fr not_active Application Discontinuation
- 1997-11-05 AU AU47189/97A patent/AU4718997A/en not_active Abandoned
- 1997-11-05 IL IL12982597A patent/IL129825A0/xx unknown
- 1997-11-05 US US09/308,602 patent/US6413971B1/en not_active Expired - Fee Related
- 1997-11-05 JP JP10524465A patent/JP2000505109A/ja active Pending
- 1997-11-07 HN HN1997000146A patent/HN1997000146A/es unknown
- 1997-11-20 PE PE1997001057A patent/PE17299A1/es not_active Application Discontinuation
- 1997-11-20 AP APAP/P/1997/001146A patent/AP9701146A0/en unknown
- 1997-11-25 AR ARP970105506A patent/AR010740A1/es unknown
- 1997-11-25 CO CO97068959A patent/CO4650037A1/es unknown
- 1997-11-26 PA PA19978442001A patent/PA8442001A1/es unknown
- 1997-11-26 ID IDP973768A patent/ID18958A/id unknown
- 1997-11-26 TN TNTNSN97192A patent/TNSN97192A1/fr unknown
- 1997-11-26 HR HR60/041,846A patent/HRP970641A2/hr not_active Application Discontinuation
- 1997-11-26 MA MA24878A patent/MA26452A1/fr unknown
-
1999
- 1999-04-30 IS IS5041A patent/IS5041A/is unknown
- 1999-05-20 BG BG103417A patent/BG103417A/xx unknown
- 1999-05-24 OA OA9900107A patent/OA11051A/en unknown
- 1999-05-26 NO NO992524A patent/NO992524D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
TNSN97192A1 (fr) | 2005-03-15 |
AP9701146A0 (en) | 1998-01-31 |
IS5041A (is) | 1999-04-30 |
PA8442001A1 (es) | 2000-05-24 |
ID18958A (id) | 1998-05-28 |
JP2000505109A (ja) | 2000-04-25 |
OA11051A (en) | 2003-03-07 |
US6413971B1 (en) | 2002-07-02 |
AU4718997A (en) | 1998-06-22 |
PE17299A1 (es) | 1999-02-19 |
NO992524L (no) | 1999-05-26 |
CN1237177A (zh) | 1999-12-01 |
CO4650037A1 (es) | 1998-09-03 |
NO992524D0 (no) | 1999-05-26 |
IL129825A0 (en) | 2000-02-29 |
US20020045630A1 (en) | 2002-04-18 |
EP0946554A1 (fr) | 1999-10-06 |
HRP970641A2 (en) | 1998-10-31 |
HN1997000146A (es) | 1998-02-26 |
CA2272705C (fr) | 2003-03-18 |
KR20000057228A (ko) | 2000-09-15 |
CA2272705A1 (fr) | 1998-06-04 |
BR9713552A (pt) | 2000-01-25 |
MA26452A1 (fr) | 2004-12-20 |
WO1998023613A1 (fr) | 1998-06-04 |
AR010740A1 (es) | 2000-07-12 |
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