BG102779A - Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo[3.2.1] octane, method for their preparation and application in therapy - Google Patents

Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo[3.2.1] octane, method for their preparation and application in therapy

Info

Publication number
BG102779A
BG102779A BG102779A BG10277998A BG102779A BG 102779 A BG102779 A BG 102779A BG 102779 A BG102779 A BG 102779A BG 10277998 A BG10277998 A BG 10277998A BG 102779 A BG102779 A BG 102779A
Authority
BG
Bulgaria
Prior art keywords
type
receptors
compounds
hydrogen
thedopaminergic
Prior art date
Application number
BG102779A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mireille Sevrin
Benoit Marabout
Pascal George
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of BG102779A publication Critical patent/BG102779A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG102779A 1996-04-12 1998-09-18 Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo[3.2.1] octane, method for their preparation and application in therapy BG102779A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
BG102779A true BG102779A (en) 1999-09-30

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102779A BG102779A (en) 1996-04-12 1998-09-18 Derivatives of 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-8-azabicyclo[3.2.1] octane, method for their preparation and application in therapy

Country Status (22)

Country Link
EP (1) EP0892800A1 (hu)
JP (1) JP2000512620A (hu)
KR (1) KR20000005392A (hu)
CN (1) CN1216046A (hu)
AR (1) AR008587A1 (hu)
AU (1) AU2640997A (hu)
BG (1) BG102779A (hu)
BR (1) BR9708654A (hu)
CA (1) CA2251335A1 (hu)
CO (1) CO4900067A1 (hu)
CZ (1) CZ326898A3 (hu)
EE (1) EE9800396A (hu)
FR (1) FR2747386B1 (hu)
IL (1) IL126473A0 (hu)
NO (1) NO984736L (hu)
NZ (1) NZ332257A (hu)
PL (1) PL329243A1 (hu)
SK (1) SK141598A3 (hu)
TR (1) TR199801839T2 (hu)
TW (1) TW407158B (hu)
WO (1) WO1997038998A1 (hu)
ZA (1) ZA973124B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ
US10870660B2 (en) 2016-07-28 2020-12-22 Shionogi & Co., Ltd. Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
CN111801330B (zh) 2018-01-26 2024-04-05 盐野义制药株式会社 具有多巴胺d3受体拮抗作用的稠环化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
JP2000512620A (ja) 2000-09-26
TW407158B (en) 2000-10-01
AU2640997A (en) 1997-11-07
IL126473A0 (en) 1999-08-17
NO984736D0 (no) 1998-10-09
WO1997038998A1 (fr) 1997-10-23
EE9800396A (et) 1999-06-15
BR9708654A (pt) 1999-08-03
AR008587A1 (es) 2000-02-09
FR2747386A1 (fr) 1997-10-17
CA2251335A1 (en) 1997-10-23
CN1216046A (zh) 1999-05-05
ZA973124B (en) 1997-11-05
KR20000005392A (ko) 2000-01-25
FR2747386B1 (fr) 1998-05-15
CO4900067A1 (es) 2000-03-27
PL329243A1 (en) 1999-03-15
NO984736L (no) 1998-11-23
EP0892800A1 (fr) 1999-01-27
CZ326898A3 (cs) 1999-01-13
SK141598A3 (en) 1999-03-12
NZ332257A (en) 1999-03-29
TR199801839T2 (hu) 1998-12-21

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