NZ332257A - 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3. 2.1]octane derivativess, their preparation and use thereof - Google Patents

3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3. 2.1]octane derivativess, their preparation and use thereof

Info

Publication number
NZ332257A
NZ332257A NZ332257A NZ33225797A NZ332257A NZ 332257 A NZ332257 A NZ 332257A NZ 332257 A NZ332257 A NZ 332257A NZ 33225797 A NZ33225797 A NZ 33225797A NZ 332257 A NZ332257 A NZ 332257A
Authority
NZ
New Zealand
Prior art keywords
derivativess
tetrahydroisoquinoline
azabicyclo
octane
methyl
Prior art date
Application number
NZ332257A
Other languages
English (en)
Inventor
Mireille Sevrin
Benoit Marabout
Pascal George
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NZ332257A publication Critical patent/NZ332257A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ332257A 1996-04-12 1997-04-10 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3. 2.1]octane derivativess, their preparation and use thereof NZ332257A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
NZ332257A true NZ332257A (en) 1999-03-29

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ332257A NZ332257A (en) 1996-04-12 1997-04-10 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3. 2.1]octane derivativess, their preparation and use thereof

Country Status (22)

Country Link
EP (1) EP0892800A1 (xx)
JP (1) JP2000512620A (xx)
KR (1) KR20000005392A (xx)
CN (1) CN1216046A (xx)
AR (1) AR008587A1 (xx)
AU (1) AU2640997A (xx)
BG (1) BG102779A (xx)
BR (1) BR9708654A (xx)
CA (1) CA2251335A1 (xx)
CO (1) CO4900067A1 (xx)
CZ (1) CZ326898A3 (xx)
EE (1) EE9800396A (xx)
FR (1) FR2747386B1 (xx)
IL (1) IL126473A0 (xx)
NO (1) NO984736L (xx)
NZ (1) NZ332257A (xx)
PL (1) PL329243A1 (xx)
SK (1) SK141598A3 (xx)
TR (1) TR199801839T2 (xx)
TW (1) TW407158B (xx)
WO (1) WO1997038998A1 (xx)
ZA (1) ZA973124B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102131790A (zh) * 2008-06-27 2011-07-20 H.隆德贝克有限公司 新型苯酚型和儿茶酚型胺及其前药
EP3495363B1 (en) 2016-07-28 2023-08-23 Shionogi & Co., Ltd Nitrogen-containing condensed ring compounds having dopamine d3 receptor antagonistic effect
MX2020007849A (es) 2018-01-26 2020-09-25 Shionogi & Co Compuesto ciclico condensado que tiene efecto antagonista del receptor de dopamina d3.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202108B (en) * 1986-07-30 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
KR20000005392A (ko) 2000-01-25
NO984736L (no) 1998-11-23
IL126473A0 (en) 1999-08-17
NO984736D0 (no) 1998-10-09
JP2000512620A (ja) 2000-09-26
AU2640997A (en) 1997-11-07
CA2251335A1 (en) 1997-10-23
SK141598A3 (en) 1999-03-12
EP0892800A1 (fr) 1999-01-27
PL329243A1 (en) 1999-03-15
BR9708654A (pt) 1999-08-03
ZA973124B (en) 1997-11-05
CN1216046A (zh) 1999-05-05
CZ326898A3 (cs) 1999-01-13
FR2747386A1 (fr) 1997-10-17
FR2747386B1 (fr) 1998-05-15
WO1997038998A1 (fr) 1997-10-23
TR199801839T2 (xx) 1998-12-21
CO4900067A1 (es) 2000-03-27
EE9800396A (et) 1999-06-15
TW407158B (en) 2000-10-01
AR008587A1 (es) 2000-02-09
BG102779A (en) 1999-09-30

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