BG101116A - Пиридилбисфосфонати и използването им като терапевтични средства - Google Patents

Пиридилбисфосфонати и използването им като терапевтични средства

Info

Publication number
BG101116A
BG101116A BG101116A BG10111697A BG101116A BG 101116 A BG101116 A BG 101116A BG 101116 A BG101116 A BG 101116A BG 10111697 A BG10111697 A BG 10111697A BG 101116 A BG101116 A BG 101116A
Authority
BG
Bulgaria
Prior art keywords
pyridylbisphosphonates
diseases
therapeutical means
therapeutical
tetraalkylesters
Prior art date
Application number
BG101116A
Other languages
English (en)
Other versions
BG63104B1 (bg
Inventor
Marjaana Heikkilae-Hoikka
Hannu Nikander
Ritva Hannuniemi
Leena Lauren
Terttu Kleimola
Sirpa Liukko-Sipi
Kalervo Vaeaenaenen
Raija Sellman
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of BG101116A publication Critical patent/BG101116A/bg
Publication of BG63104B1 publication Critical patent/BG63104B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Изобретението се отнася до заместени в пръстена тетраалкилови естери на пиридиниламинометилиден бисфосфонова киселина (I) и до използването им за лечение на костни заболявания като остеолитични заболявания, дължащи се на злокачествено развитие, болест на Paget и първични и вторични остеопорози.
BG101116A 1994-06-09 1997-01-06 Пиридилбисфосфонати и използването им като терапевтични средства BG63104B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402001A SE9402001D0 (sv) 1994-06-09 1994-06-09 Pyridylbisphosphonates for use as a therapeutical agent
PCT/FI1995/000315 WO1995033466A1 (en) 1994-06-09 1995-06-02 Pyridylbisphosphonates for use as a therapeutical agent

Publications (2)

Publication Number Publication Date
BG101116A true BG101116A (bg) 1998-03-31
BG63104B1 BG63104B1 (bg) 2001-04-30

Family

ID=20394303

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101116A BG63104B1 (bg) 1994-06-09 1997-01-06 Пиридилбисфосфонати и използването им като терапевтични средства

Country Status (27)

Country Link
US (2) US5866556A (bg)
EP (1) EP0762883B1 (bg)
JP (1) JP3883137B2 (bg)
KR (1) KR100363692B1 (bg)
CN (1) CN1077792C (bg)
AT (1) ATE208622T1 (bg)
AU (1) AU691616B2 (bg)
BG (1) BG63104B1 (bg)
BR (1) BR9508185A (bg)
CZ (1) CZ291477B6 (bg)
DE (1) DE69523914T2 (bg)
DK (1) DK0762883T3 (bg)
EE (1) EE03475B1 (bg)
ES (1) ES2162919T3 (bg)
HK (1) HK1012572A1 (bg)
HU (1) HU228618B1 (bg)
IS (1) IS1801B (bg)
NO (1) NO311069B1 (bg)
NZ (1) NZ287094A (bg)
PL (1) PL180705B1 (bg)
PT (1) PT762883E (bg)
RO (1) RO119433B1 (bg)
RU (1) RU2154482C2 (bg)
SE (1) SE9402001D0 (bg)
SK (1) SK282650B6 (bg)
UA (1) UA43918C2 (bg)
WO (1) WO1995033466A1 (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU775079B2 (en) * 1999-05-21 2004-07-15 Novartis Ag Pharmaceutical compositions and uses
US7115589B2 (en) 1999-12-17 2006-10-03 Ariad Pharmaceuticals, Inc. Purine derivatives
AU2583901A (en) * 1999-12-17 2001-06-25 Ariad Pharmaceuticals, Inc. Proton pump inhibitors
WO2001044258A1 (en) * 1999-12-17 2001-06-21 Ariad Pharmaceuticals, Inc. Novel heterocycles
ES2282306T3 (es) * 2000-10-27 2007-10-16 Bayer Schering Pharma Aktiengesellschaft Compuestos bisfosfonicos para fortalecer en hueso conrtical.
WO2003070169A2 (en) * 2002-02-19 2003-08-28 Ilex Products, Inc. Aminodiphosphonate apolipoprotein e modulators
TW200413381A (en) * 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
US20050010305A1 (en) * 2003-01-28 2005-01-13 Lee Francis Y. Novel bone graft composite
US20050065171A1 (en) * 2003-06-25 2005-03-24 Shakespeare William C. Substituted purine derivatives
JP2005060303A (ja) * 2003-08-12 2005-03-10 Sutaagen:Kk 不動性骨粗鬆の治療または予防剤
US7862552B2 (en) * 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US447256A (en) * 1891-02-24 Apparatus for flashing and exhausting incandescent electric lamps
US4447256A (en) * 1977-07-20 1984-05-08 Nissan Chemical Industries, Ltd. N-(Unsubstituted or substituted pyridyl)aminomethylene-diphosphonic acids, herbicidal compositions containing same, their use for herbicides, and process for preparing same
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US4973576A (en) * 1987-03-10 1990-11-27 Yamanouchi Pharmaceutical Co., Ltd. Bisphophonic acid derivatives and pharmaceutical compositions containing the same
KR880011136A (ko) * 1987-03-11 1988-10-26 모리오까 시게오 아졸- 아미노메틸렌 비스포스폰산 유도체

Also Published As

Publication number Publication date
DK0762883T3 (da) 2002-03-11
HU9603375D0 (en) 1997-01-28
WO1995033466A1 (en) 1995-12-14
CZ291477B6 (cs) 2003-03-12
SK282650B6 (sk) 2002-10-08
DE69523914T2 (de) 2002-06-27
KR100363692B1 (ko) 2003-02-07
BR9508185A (pt) 1997-08-12
BG63104B1 (bg) 2001-04-30
NO311069B1 (no) 2001-10-08
HU228618B1 (en) 2013-04-29
RU2154482C2 (ru) 2000-08-20
EE03475B1 (et) 2001-08-15
AU2569895A (en) 1996-01-04
US6083938A (en) 2000-07-04
IS1801B (is) 2002-01-22
ES2162919T3 (es) 2002-01-16
CN1149830A (zh) 1997-05-14
US5866556A (en) 1999-02-02
PT762883E (pt) 2002-05-31
NZ287094A (en) 1998-04-27
ATE208622T1 (de) 2001-11-15
JP3883137B2 (ja) 2007-02-21
HUT75525A (en) 1997-05-28
KR970703152A (ko) 1997-07-03
UA43918C2 (uk) 2002-01-15
SK157296A3 (en) 1997-06-04
NO965228L (no) 1996-12-06
IS4392A (is) 1996-12-02
EP0762883B1 (en) 2001-11-14
CN1077792C (zh) 2002-01-16
JPH10500977A (ja) 1998-01-27
PL180705B1 (pl) 2001-03-30
EP0762883A1 (en) 1997-03-19
DE69523914D1 (en) 2001-12-20
EE9600191A (et) 1997-06-16
SE9402001D0 (sv) 1994-06-09
PL317612A1 (en) 1997-04-14
AU691616B2 (en) 1998-05-21
HK1012572A1 (en) 1999-08-06
NO965228D0 (no) 1996-12-06
RO119433B1 (ro) 2004-11-30
CZ356196A3 (en) 1997-07-16

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