BG100525A - Хетероатомни бензоциклопентанови оксазолидинони с антибактерицидна активност - Google Patents

Хетероатомни бензоциклопентанови оксазолидинони с антибактерицидна активност

Info

Publication number
BG100525A
BG100525A BG100525A BG10052596A BG100525A BG 100525 A BG100525 A BG 100525A BG 100525 A BG100525 A BG 100525A BG 10052596 A BG10052596 A BG 10052596A BG 100525 A BG100525 A BG 100525A
Authority
BG
Bulgaria
Prior art keywords
oxazolidinons
benzocyclopantane
heteroatomic
formula
antibactericidal
Prior art date
Application number
BG100525A
Other languages
English (en)
Inventor
21>
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19544106A external-priority patent/DE19544106A1/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG100525A publication Critical patent/BG100525A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретението се отнася до бензоциклопентаноксазолидинони, съдържащи хетероатоми, до методи за получаването им и до приложенията им като лекарствени средства, по-специално като бактерицидни. Съединенията имат обща формула в която r1 означава азидо, хидрокси или група с формула -оr2, -о-sо2r3 или -nr4r5; а е специфичен остатък с формула или а g, l и м са еднакви или различни и означават водород, карбокси, халоген, циано, формил, трифлуорометил, нитрогрупа или алкил с1-с6, или -соnr17r18.
BG100525A 1995-04-21 1996-04-19 Хетероатомни бензоциклопентанови оксазолидинони с антибактерицидна активност BG100525A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19514769 1995-04-21
DE19544106A DE19544106A1 (de) 1995-04-21 1995-11-27 Heteroatomhaltige Benzocyclopentanoxazolidinone

Publications (1)

Publication Number Publication Date
BG100525A true BG100525A (bg) 1997-03-31

Family

ID=26014539

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100525A BG100525A (bg) 1995-04-21 1996-04-19 Хетероатомни бензоциклопентанови оксазолидинони с антибактерицидна активност

Country Status (21)

Country Link
US (1) US6069160A (bg)
EP (1) EP0738726B1 (bg)
JP (1) JP3967401B2 (bg)
CN (1) CN1138582A (bg)
AT (1) ATE206120T1 (bg)
AU (1) AU705071B2 (bg)
BG (1) BG100525A (bg)
CA (1) CA2174473A1 (bg)
CZ (1) CZ114296A3 (bg)
EE (1) EE9600043A (bg)
ES (1) ES2164182T3 (bg)
HR (1) HRP960159A2 (bg)
HU (1) HUP9601001A3 (bg)
IL (1) IL117954A0 (bg)
MA (1) MA23845A1 (bg)
MX (1) MX9601399A (bg)
NO (1) NO305909B1 (bg)
NZ (1) NZ286400A (bg)
SG (1) SG52774A1 (bg)
SK (1) SK50096A3 (bg)
TR (1) TR199600319A2 (bg)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114075439A (zh) * 2021-12-07 2022-02-22 西安瑞联新材料股份有限公司 一种苯并戊烷类液晶化合物及其组合物

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
US6617453B1 (en) 1997-10-24 2003-09-09 Clariant Finance (Bvi) Limited Triphendioxazine compounds
DE19747175A1 (de) * 1997-10-24 1999-04-29 Clariant Int Ltd Chlorhaltige Triphendioxazin-Verbindungen
IL135176A0 (en) 1997-11-10 2001-05-20 Bristol Myers Squibb Co Benzothiazole derivatives and pharmaceutical compositions containing the same
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
WO1999037630A1 (en) 1998-01-23 1999-07-29 Versicor, Inc. Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
WO2000029409A1 (de) * 1998-11-17 2000-05-25 Bayer Aktiengesellschaft Neue heterocyclyl-substituierte oxazolidon-derivate
DE19905278A1 (de) * 1999-02-09 2000-08-10 Bayer Ag Oxazolidinone und ihre Verwendung als antibakterielle Mittel
DE19913401A1 (de) 1999-03-25 2000-09-28 Clariant Gmbh Verfahren zur Herstellung von Dioxazin-Verbindungen
BR0012742A (pt) * 1999-07-28 2002-06-11 Upjohn Co Oxazolidinonas e seus usos como antibiótico
GB9928568D0 (en) * 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) * 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
PE20011124A1 (es) 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6833453B2 (en) * 2000-10-17 2004-12-21 Pharmacia & Upjohn Company Methods of producing oxazolidinone compounds
EP1341769B1 (en) * 2000-12-15 2007-10-17 Vertex Pharmaceuticals Incorporated Bacterial gyrase inhibitors and uses thereof
DE60206154T2 (de) * 2001-04-17 2006-06-29 Merck & Co., Inc. Bicyclo[3,1,0]hexan als strukturelement enthaltende oxazolidinon-antibiotika und deren derivate
EP1598340B1 (en) 2001-04-18 2009-03-04 Euro-Celtique S.A. 1-(4-piperidinyl)-1,3-dihydro-2h-benzoxazole-2-one derivatives and related compounds as nociceptin analogs and orl1 ligands for the treatment of pain
DE10129725A1 (de) * 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
US6686363B2 (en) 2001-11-29 2004-02-03 Kyorin Pharmaceutical Co., Ltd. Cyclopropyl containing oxazolidinone antibiotics and derivatives thereof
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
MXPA04009356A (es) * 2002-03-29 2005-01-25 Pharmacia & Upjohn Co Llc Administracion parenteral, intravenosa y oral de oxazolidinonas para tratar infecciones de pie diabetico.
CA2491287A1 (en) * 2002-08-12 2004-02-19 Pharmacia & Upjohn Company N-aryl-2-oxazolidinones and their derivatives
WO2004026848A1 (en) * 2002-09-20 2004-04-01 Lupin Limited Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents
ATE344036T1 (de) * 2002-11-21 2006-11-15 Pharmacia & Upjohn Co Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
US7569591B2 (en) 2003-01-31 2009-08-04 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US8404852B2 (en) 2003-01-31 2013-03-26 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7618974B2 (en) 2003-01-31 2009-11-17 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7582641B2 (en) 2003-01-31 2009-09-01 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8193352B2 (en) 2003-01-31 2012-06-05 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
WO2004069832A2 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
CA2529293A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
CA2529292A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
WO2005005422A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
KR20060113625A (ko) * 2003-07-02 2006-11-02 머크 앤드 캄파니 인코포레이티드 시클로프로필기 치환된 옥사졸리디논 항생제 및 그의유도체
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
WO2005082897A1 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
CA2575702A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxindole oxazolidinones as antibacterial agents
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
BRPI0607873A2 (pt) * 2005-04-06 2009-10-20 Pharmacia & Upjohn Co Llc oxazolidinona de oxindol como agente antibacteriano
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
EP1934208B1 (de) 2005-10-04 2011-03-23 Bayer Schering Pharma Aktiengesellschaft Neue polymorphe form von 5-chlor-n-({ ( 5s )-2-0x0-3-[4-( 3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl} -methyl)-2-thiophencarboxamid
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE102005048824A1 (de) * 2005-10-10 2007-04-12 Bayer Healthcare Ag Behandlung und Prophylaxe von Mikroangiopathien
DE102006051625A1 (de) * 2006-11-02 2008-05-08 Bayer Materialscience Ag Kombinationstherapie substituierter Oxazolidinone
JP6120775B2 (ja) 2011-01-14 2017-04-26 スペロ トリネム， インコーポレイテッド ジャイレース阻害剤である（ｒ）−１−エチル−３−［６−フルオロ−５−［２−（１−ヒドロキシ−１−メチル−エチル）ピリミジン−５−イル］−７−（テトラヒドロフラン−２−イル）−１ｈ−ベンゾイミダゾール−２−イル］尿素の固体形態
EP2663556B1 (en) 2011-01-14 2014-10-15 Vertex Pharmaceuticals Incorporated Process of making gyrase and topoisomerase iv inhibitors
EP2663557B1 (en) 2011-01-14 2015-05-27 Vertex Pharmaceuticals Incorporated Pyrimidine gyrase and topoisomerase iv inhibitors
JP2014507413A (ja) 2011-01-14 2014-03-27 バーテックス ファーマシューティカルズ インコーポレイテッド ジャイレース阻害剤である（ｒ）−１−エチル−３−［５−［２−（１−ヒドロキシ−１−メチル−エチル）ピリミジン−５−イル］−７−（テトラヒドロフラン−２−イル）−１ｈ−ベンゾイミダゾール−２−イル］尿素の固体形態
TWI554515B (zh) 2011-06-20 2016-10-21 維泰克斯製藥公司 旋轉酶（ｇｙｒａｓｅ）及拓樸異構酶抑制劑之磷酸酯
AR093226A1 (es) 2012-07-18 2015-05-27 Vertex Pharma Formas solidas de dihidrogeno fosfato de (r)-2-(5-(2-(3-etilureido)-6-fluoro-7-(tetrahidrofuran-2-il)-1h-benzo[d]imidazol-5-il)pirimidin-2-il)propan-2-ilo y sus sales
US9572809B2 (en) 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases
KR102161867B1 (ko) * 2013-01-30 2020-10-05 스미또모 가가꾸 가부시끼가이샤 유해 절족동물의 방제 방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
DE3723797A1 (de) * 1987-07-18 1989-01-26 Merck Patent Gmbh Oxazolidinone
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) * 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
ATE112773T1 (de) * 1988-09-15 1994-10-15 Upjohn Co 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
JP2669579B2 (ja) * 1991-10-23 1997-10-29 エーザイ株式会社 オキサゾリドン誘導体
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114075439A (zh) * 2021-12-07 2022-02-22 西安瑞联新材料股份有限公司 一种苯并戊烷类液晶化合物及其组合物
CN114075439B (zh) * 2021-12-07 2023-07-28 西安瑞联新材料股份有限公司 一种苯并戊烷类液晶化合物及其组合物

Also Published As

Publication number Publication date
JP3967401B2 (ja) 2007-08-29
IL117954A0 (en) 1996-08-04
NZ286400A (en) 1998-04-27
CA2174473A1 (en) 1996-10-22
SG52774A1 (en) 1998-09-28
EE9600043A (et) 1996-12-16
NO305909B1 (no) 1999-08-16
NO961559D0 (no) 1996-04-19
CZ114296A3 (en) 1997-07-16
ES2164182T3 (es) 2002-02-16
MA23845A1 (fr) 1996-12-31
AU705071B2 (en) 1999-05-13
EP0738726B1 (de) 2001-09-26
MX9601399A (es) 1997-04-30
JPH08301869A (ja) 1996-11-19
US6069160A (en) 2000-05-30
NO961559L (no) 1996-10-22
TR199600319A2 (tr) 1996-11-21
HRP960159A2 (en) 1997-08-31
CN1138582A (zh) 1996-12-25
ATE206120T1 (de) 2001-10-15
AU5073596A (en) 1996-10-31
SK50096A3 (en) 1997-05-07
HUP9601001A2 (hu) 1998-04-28
EP0738726A1 (de) 1996-10-23
HU9601001D0 (en) 1996-06-28
HUP9601001A3 (en) 1999-03-01

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