BG102238A - Нови имидазолин-2,4-диони с антиконвулсивно действие, съдържащи в 1-ва позиция един ортозаместен ар(алк)илов радикал, и метод за тяхното получаване - Google Patents

Нови имидазолин-2,4-диони с антиконвулсивно действие, съдържащи в 1-ва позиция един ортозаместен ар(алк)илов радикал, и метод за тяхното получаване

Info

Publication number
BG102238A
BG102238A BG102238A BG10223898A BG102238A BG 102238 A BG102238 A BG 102238A BG 102238 A BG102238 A BG 102238A BG 10223898 A BG10223898 A BG 10223898A BG 102238 A BG102238 A BG 102238A
Authority
BG
Bulgaria
Prior art keywords
orthosubstituted
dions
alk
radical
preparation
Prior art date
Application number
BG102238A
Other languages
English (en)
Inventor
Hans-Joachim Lankau
Manfred Menzer
Angelika Rostock
Klaus Unverferth
Original Assignee
Arzneimittelwerk Dresden Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden Gmbh filed Critical Arzneimittelwerk Dresden Gmbh
Publication of BG102238A publication Critical patent/BG102238A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Съединенията проявяват антиконвулсивно действие. Те имат обща формула в която Х означава С1-С4алкил, трифлуорметил и халоген, Y - водород и халоген, n има стойност 0 и 1, а m - 0, 1, 2, 3 и 4.
BG102238A 1995-08-10 1998-02-09 Нови имидазолин-2,4-диони с антиконвулсивно действие, съдържащи в 1-ва позиция един ортозаместен ар(алк)илов радикал, и метод за тяхното получаване BG102238A (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19529425A DE19529425A1 (de) 1995-08-10 1995-08-10 Neue, antikonvulsiv wirkende Imidazolin-2,4-dione, die in 1-Stellung einen orthosubstituierten Ar(alk)yl-Rest enthalten, und Verfahren zu deren Herstellung
PCT/EP1996/003296 WO1997006149A1 (de) 1995-08-10 1996-07-26 Neue, antikonvulsiv wirkende imidazolin-2,4-dione, die in 1-stellung einen orthosubstituierten ar(alk)yl-rest enthalten, und verfahren zu deren herstellung
US08/700,876 US5817685A (en) 1995-08-10 1996-08-21 Anticonvulsive imidazoline-2,4-diones and process for making
CA002183928A CA2183928A1 (en) 1995-08-10 1996-08-22 Anticonvulsive imidazoline-2,4-diones and process for making

Publications (1)

Publication Number Publication Date
BG102238A true BG102238A (bg) 1998-09-30

Family

ID=27170189

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102238A BG102238A (bg) 1995-08-10 1998-02-09 Нови имидазолин-2,4-диони с антиконвулсивно действие, съдържащи в 1-ва позиция един ортозаместен ар(алк)илов радикал, и метод за тяхното получаване

Country Status (14)

Country Link
US (1) US5817685A (bg)
EP (1) EP0850226A1 (bg)
CN (1) CN1192736A (bg)
AU (1) AU699802B2 (bg)
BG (1) BG102238A (bg)
CA (1) CA2183928A1 (bg)
CZ (1) CZ38298A3 (bg)
DE (1) DE19529425A1 (bg)
IL (1) IL123296A0 (bg)
LT (1) LT4457B (bg)
NO (1) NO980309D0 (bg)
NZ (1) NZ315625A (bg)
PL (1) PL327452A1 (bg)
WO (1) WO1997006149A1 (bg)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2443906A1 (en) * 2001-04-16 2002-10-24 University Of Virginia Patent Foundation Novel oral general anesthetics and metabolitically resistant anticonvulsants
CN101255136B (zh) * 2008-03-11 2011-08-17 武汉大学 5-环丙烷螺环乙内酰脲衍生物及其制备方法和应用
ATE525941T1 (de) * 2009-10-23 2011-10-15 Gruppo Cimbali Spa Kaffeemaschine mit abgabedruckregulierung und damit zusammenhängendes verfahren
CN101863839B (zh) * 2010-06-04 2012-02-15 武汉大学 N-3-芳酰胺-5-环丙烷螺环乙内酰脲衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB997037A (en) * 1962-03-19 1965-06-30 Ici Ltd New hydrantoin derivatives
JPH05178802A (ja) * 1991-12-27 1993-07-20 Sumitomo Seika Chem Co Ltd Ｎ−ベンジルグリシンおよびその誘導体の製造方法
TW297813B (bg) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
NO980309L (no) 1998-01-23
LT98030A (en) 1998-09-25
WO1997006149A1 (de) 1997-02-20
AU6737696A (en) 1997-03-05
CN1192736A (zh) 1998-09-09
AU699802B2 (en) 1998-12-17
PL327452A1 (en) 1998-12-07
DE19529425A1 (de) 1997-02-13
IL123296A0 (en) 1998-10-30
NO980309D0 (no) 1998-01-23
CZ38298A3 (cs) 1998-09-16
CA2183928A1 (en) 1998-02-23
US5817685A (en) 1998-10-06
EP0850226A1 (de) 1998-07-01
LT4457B (lt) 1999-02-25
NZ315625A (en) 1999-01-28

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