BE903168A - Nouveaux analogues 6-substitues de la mitomycine - Google Patents

Nouveaux analogues 6-substitues de la mitomycine

Info

Publication number
BE903168A
BE903168A BE0/215534A BE215534A BE903168A BE 903168 A BE903168 A BE 903168A BE 0/215534 A BE0/215534 A BE 0/215534A BE 215534 A BE215534 A BE 215534A BE 903168 A BE903168 A BE 903168A
Authority
BE
Belgium
Prior art keywords
new
mitomycin analogs
approximately
substituted mitomycin
substituted
Prior art date
Application number
BE0/215534A
Other languages
English (en)
Inventor
W A Remers
S Sami
Original Assignee
Univ Parents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Parents Inc filed Critical Univ Parents Inc
Publication of BE903168A publication Critical patent/BE903168A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Composition pharmaceutique pour le traitement d'une affection néoplasique chez un animal, qui comprend un solvant, diluant, adjuvant ou excipient pharmaceutiquement acceptable et, comme constituant actif, environ 0,4 mg à environ 12,8 mg d'un composé de formule I par exemple, le carbamate de 1,1a,2,8,8a,8b-hexahydro-8- (hydroxyméthyl) -8a-méthoxy-5-méthyl-6- (allyloxy) -azirino/2',3':3,4/pyrrolo/1,2-a/indole-4,7-dione.
BE0/215534A 1984-09-04 1985-09-03 Nouveaux analogues 6-substitues de la mitomycine BE903168A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/647,055 US4888341A (en) 1984-09-04 1984-09-04 6-substituted mitomycin analogs

Publications (1)

Publication Number Publication Date
BE903168A true BE903168A (fr) 1985-12-31

Family

ID=24595518

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215534A BE903168A (fr) 1984-09-04 1985-09-03 Nouveaux analogues 6-substitues de la mitomycine

Country Status (23)

Country Link
US (1) US4888341A (fr)
JP (1) JPS6168489A (fr)
KR (1) KR900006855B1 (fr)
AT (1) AT391318B (fr)
AU (1) AU593773B2 (fr)
BE (1) BE903168A (fr)
CA (1) CA1249278A (fr)
CH (1) CH666036A5 (fr)
DE (1) DE3531197A1 (fr)
DK (1) DK399985A (fr)
ES (2) ES8800225A1 (fr)
FI (1) FI81581C (fr)
FR (1) FR2569697B1 (fr)
GB (1) GB2164036B (fr)
GR (1) GR852066B (fr)
HU (1) HU194884B (fr)
IT (1) IT1203633B (fr)
LU (1) LU86059A1 (fr)
NL (1) NL8502203A (fr)
NO (1) NO162618C (fr)
PT (1) PT81084B (fr)
SE (1) SE468212B (fr)
ZA (1) ZA854452B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927943A (en) * 1984-09-04 1990-05-22 Bristol-Myers Company Substituted 7-oxomitosanes
US5097036A (en) * 1984-09-04 1992-03-17 Bristol-Myers Company Substituted 7-oxomitosanes
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
CA1282069C (fr) * 1985-09-12 1991-03-26 Damon L. Meyer Complexes d'anticorps comprenant des agents therapeutiques ou de diagnostic modifies par des haptenes
DE3871836T2 (de) * 1987-03-25 1993-01-14 Kyowa Hakko Kogyo Kk Mitomycin-derivate.
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
US5099016A (en) * 1988-11-07 1992-03-24 Bristol-Myers Company Substituted 7-oxomitosanes
EP0485904B1 (fr) * 1990-11-13 1997-08-20 Kyowa Hakko Kogyo Co., Ltd. Dérivés de la mitomycine
DE10212359B4 (de) * 2002-03-20 2005-10-06 Peter Lisec Verfahren und Vorrichtung zum maschinellen Applizieren eines Abstandhalterbandes auf eine Glasscheibe

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA770608A (en) * 1967-10-31 Matsui Masanao 1a-substituted mitomycin
CA770128A (en) * 1967-10-24 Matsui Masanao 7-HYDROXY-9.alpha.-METHOXY MITOSANE AND PROCESS FOR PREPARING THE SAME
US3306821A (en) * 1962-09-04 1967-02-28 Upjohn Co Porfiromycin derivatives and method of making same
NL132363C (fr) * 1964-07-10
DE1570030A1 (de) * 1964-07-11 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von in 1a-Stellung substituierten Mitomycinverbindungen
JPS5748985A (en) * 1980-09-09 1982-03-20 Kyowa Hakko Kogyo Co Ltd Novel mitomycin derivative
US4746746A (en) * 1983-02-07 1988-05-24 University Patents, Inc. Mitomycin analogs
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4814445A (en) * 1984-09-04 1989-03-21 Bristol-Myers Company Process for preparing mitomycin analogs
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes

Also Published As

Publication number Publication date
FI81581C (fi) 1990-11-12
SE8504113D0 (sv) 1985-09-04
JPS6168489A (ja) 1986-04-08
HUT39451A (en) 1986-09-29
SE468212B (sv) 1992-11-23
ES546690A0 (es) 1987-10-16
FI853181A0 (fi) 1985-08-19
NO853468L (no) 1986-03-05
KR860002506A (ko) 1986-04-26
GR852066B (fr) 1985-12-23
ES8800227A1 (es) 1987-10-16
PT81084B (pt) 1987-10-20
AU593773B2 (en) 1990-02-22
IT1203633B (it) 1989-02-15
LU86059A1 (fr) 1986-02-18
CH666036A5 (de) 1988-06-30
NO162618B (no) 1989-10-16
DE3531197A1 (de) 1986-03-06
GB8518099D0 (en) 1985-08-21
PT81084A (en) 1985-10-01
IT8567722A0 (it) 1985-08-09
AT391318B (de) 1990-09-25
FR2569697B1 (fr) 1990-01-05
GB2164036A (en) 1986-03-12
AU4588285A (en) 1986-03-13
SE8504113L (sv) 1986-03-05
ZA854452B (en) 1986-02-26
ES557566A0 (es) 1987-10-16
US4888341A (en) 1989-12-19
NL8502203A (nl) 1986-04-01
ES8800225A1 (es) 1987-10-16
DK399985D0 (da) 1985-09-02
GB2164036B (en) 1988-06-02
NO162618C (no) 1990-01-24
HU194884B (en) 1988-03-28
FI81581B (fi) 1990-07-31
DK399985A (da) 1986-03-05
KR900006855B1 (ko) 1990-09-22
FR2569697A1 (fr) 1986-03-07
FI853181L (fi) 1986-03-05
CA1249278A (fr) 1989-01-24
ATA218185A (de) 1990-03-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: UNIVERSITY PARENTS INC.

Effective date: 19960930