BE901958A - Derives de 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2h, 4h-(1,3)-oxazino - ou - thiazino (4,3,a) isoquinoleine, procede pour leur preparation et compo - Google Patents

Derives de 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2h, 4h-(1,3)-oxazino - ou - thiazino (4,3,a) isoquinoleine, procede pour leur preparation et compo

Info

Publication number
BE901958A
BE901958A BE1/11214A BE1011214A BE901958A BE 901958 A BE901958 A BE 901958A BE 1/11214 A BE1/11214 A BE 1/11214A BE 1011214 A BE1011214 A BE 1011214A BE 901958 A BE901958 A BE 901958A
Authority
BE
Belgium
Prior art keywords
derivatives
thiazino
oxazino
tetrahydro
hydroxymethyl
Prior art date
Application number
BE1/11214A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of BE901958A publication Critical patent/BE901958A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Dérivés de 1-(hydroxyméthyul)-1.6.7.11b-tétrahydro-2H, 4H(1,3) oxazino- ou -thiazino (4,3-a) isoquinoléine représentés par la formule (I), dans laquelle, R1 et R2 sont des groupes alcoxy ayant 1 à 6 atomes de carbone, X est un atome d'oxygène ou de soufre, Y est =0, =S ou un groupe =NR3. Les dérivés de formule I présentenet une action vasodilatatrice antispasmodique et antidiamerhéique.
BE1/11214A 1984-03-23 1985-03-18 Derives de 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2h, 4h-(1,3)-oxazino - ou - thiazino (4,3,a) isoquinoleine, procede pour leur preparation et compo BE901958A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU841162A HU191301B (en) 1984-03-23 1984-03-23 Process for preparing 1-/hydroxy-methyl/-1,6,7,11b-tetrahydro-2h,4h-/1,3/-oxazino- or -thiazino/4,3-a/isoquinoline -derivatives

Publications (1)

Publication Number Publication Date
BE901958A true BE901958A (fr) 1985-09-18

Family

ID=10953111

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/11214A BE901958A (fr) 1984-03-23 1985-03-18 Derives de 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2h, 4h-(1,3)-oxazino - ou - thiazino (4,3,a) isoquinoleine, procede pour leur preparation et compo

Country Status (16)

Country Link
US (1) US4605653A (fr)
JP (1) JPS60260581A (fr)
AR (2) AR240644A1 (fr)
AT (1) AT385756B (fr)
BE (1) BE901958A (fr)
CA (1) CA1288100C (fr)
CH (1) CH665419A5 (fr)
DE (1) DE3510526A1 (fr)
DK (1) DK163061C (fr)
FI (1) FI79321C (fr)
FR (1) FR2561647B1 (fr)
GB (1) GB2157289B (fr)
HU (1) HU191301B (fr)
IT (1) IT1187643B (fr)
NL (1) NL8500839A (fr)
SE (1) SE462850B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3722827A1 (de) * 1987-07-07 1989-01-19 Schering Ag Anellierte imino-azole und imino-azine, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider wirkung
HU209393B (en) * 1991-12-12 1994-05-30 Richter Gedeon Vegyeszet Process for producing new, substituted oxazinoisoquinoline derivates
US8412377B2 (en) 2000-01-24 2013-04-02 Irobot Corporation Obstacle following sensor scheme for a mobile robot
US6956348B2 (en) 2004-01-28 2005-10-18 Irobot Corporation Debris sensor for cleaning apparatus
US6690134B1 (en) 2001-01-24 2004-02-10 Irobot Corporation Method and system for robot localization and confinement
KR100429356B1 (ko) * 2001-04-23 2004-05-31 조수동 다약제 내성 극복 이소퀴놀린계 화합물 및 그 제조방법
US8396592B2 (en) 2001-06-12 2013-03-12 Irobot Corporation Method and system for multi-mode coverage for an autonomous robot
US8428778B2 (en) 2002-09-13 2013-04-23 Irobot Corporation Navigational control system for a robotic device
US8386081B2 (en) 2002-09-13 2013-02-26 Irobot Corporation Navigational control system for a robotic device
US7332890B2 (en) 2004-01-21 2008-02-19 Irobot Corporation Autonomous robot auto-docking and energy management systems and methods
US8392021B2 (en) 2005-02-18 2013-03-05 Irobot Corporation Autonomous surface cleaning robot for wet cleaning
ES2346343T3 (es) 2005-02-18 2010-10-14 Irobot Corporation Robot autonomo de limpieza de superficies para una limpieza en seco y en mojado.
ES2718831T3 (es) 2005-12-02 2019-07-04 Irobot Corp Sistema de robots
EP2466411B1 (fr) 2005-12-02 2018-10-17 iRobot Corporation Système de robot
EP2548492B1 (fr) 2006-05-19 2016-04-20 iRobot Corporation Élimination de débris de robots de nettoyage
US8417383B2 (en) 2006-05-31 2013-04-09 Irobot Corporation Detecting robot stasis
KR101301834B1 (ko) 2007-05-09 2013-08-29 아이로보트 코퍼레이션 소형 자율 커버리지 로봇
EP3192419B1 (fr) 2010-02-16 2021-04-07 iRobot Corporation Brosse d'aspirateur

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985649A (en) * 1959-09-17 1961-05-23 Pfizer & Co C Derivatives of thiabenzopyrrocoline, thiabenzopyridocoline and thiazepine
US3042671A (en) * 1959-10-07 1962-07-03 Pfizer & Co C Benzopyridocolines
US3157573A (en) * 1962-12-18 1964-11-17 Hoffmann La Roche Antihypertensive 3, 4-dihydro-2(1h)-isoquinolinecarboxamidine
US3389141A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-aryloxyethyltetrahydro-isoquinolines
SE343586B (fr) * 1967-05-01 1972-03-13 Ciba Geigy Ag
IE37234B1 (en) * 1972-02-14 1977-06-08 Ayerst Mckenna & Harrison Fused-ring indole derivatives
HU190458B (en) * 1983-10-25 1986-09-29 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing /1,3/ oxazino /4,3-a/ isoquinoline-derivatives

Also Published As

Publication number Publication date
AT385756B (de) 1988-05-10
US4605653A (en) 1986-08-12
HU191301B (en) 1987-02-27
JPS60260581A (ja) 1985-12-23
SE8501421L (sv) 1985-09-24
AR240644A1 (es) 1990-07-31
CH665419A5 (de) 1988-05-13
CA1288100C (fr) 1991-08-27
GB8507526D0 (en) 1985-05-01
JPH0523269B2 (fr) 1993-04-02
GB2157289A (en) 1985-10-23
DK163061B (da) 1992-01-13
SE462850B (sv) 1990-09-10
DK129885D0 (da) 1985-03-22
IT8520023A0 (it) 1985-03-22
FI79321C (fi) 1989-12-11
ATA86585A (de) 1987-10-15
DK163061C (da) 1992-06-09
FI851155A0 (fi) 1985-03-22
AR240325A1 (es) 1990-03-30
NL8500839A (nl) 1985-10-16
HUT37941A (en) 1986-03-28
GB2157289B (en) 1987-07-29
IT1187643B (it) 1987-12-23
FI851155L (fi) 1985-09-24
DE3510526A1 (de) 1985-10-03
FR2561647A1 (fr) 1985-09-27
FI79321B (fi) 1989-08-31
SE8501421D0 (sv) 1985-03-22
FR2561647B1 (fr) 1987-04-24
DK129885A (da) 1985-09-24

Similar Documents

Publication Publication Date Title
BE901958A (fr) Derives de 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2h, 4h-(1,3)-oxazino - ou - thiazino (4,3,a) isoquinoleine, procede pour leur preparation et compo
TNSN86111A1 (fr) Procede de preparation d'hydroxyalkylxanthines tertiaires
DK463986A (da) (n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
BE902953A (fr) Derives de 5h-2,3-benzodiazepine procede pour les preparer et compositions pharmaceutiques les contenant
BE1002211A4 (fr) (pentamethyl-1,2,2,6,6 piperidyl-4-amino)-triazines, leur application comme stabilisants de matieres organiques, et compositions qui en contiennent.
FR2457300A1 (fr) Nouveaux derives d'alkyl-cetohexopyranosides, leurs procedes de preparation et leur application en therapeutique
DE68917357D1 (de) Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten.
BE902876A (fr) Derives d'aminophenol
TNSN86144A1 (fr) Procede pour la preparation de derives de la flavone
BE901239A (fr) Nouveaux derives d'aminoguanidine et procede pour leur preparation.
ATE41772T1 (de) Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
FR2452483A1 (fr) Derives d'alcenylphenylmaleimides, leurs dimeres lineaires et leur procede de preparation
FR2636946A1 (fr) ((diarylmethoxy)alcoyl)-1 pyrrolidines et piperidines, procedes de preparation et medicaments les contenant
ES8704153A1 (es) Un procedimiento para preparar derivados de pirimidina
FR2506313A1 (fr) Derives de l'acide n-acetylneuraminique et leur preparation
ES481551A1 (es) Procedimiento de preparacion de nuevos compuestos bis (ari- loxicarboxilicos).
FR2447375A1 (fr) Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
FR2411173A1 (fr) Anthranilates de n-hydroxyalkyl-carboxamides et leur application comme reticulants
BE902249A (fr) Derives d'iminothiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2436134A1 (fr) Derives d'acide hydroxamique, leur procede de preparation et medicament les contenant
KR910006310A (ko) 신규한 나프탈렌 및 테트라히드로 나프탈렌 치환된 겜-디포스포네이트 유도체
EP0335758A3 (fr) Dérivés de la 1-arylsulfonyl 2-pyrrolidinone, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant
OA09139A (fr) Nouveaux dérivés de la carbonyl-2 N, N'-di-(triméthoxy-benzoyle) pipérazine, un procédé pour leur préparation et compositions thérapeutiques en contenant.
FR2603589A1 (fr) Compose (phenyldimethylcarbinyl)-silane et son procede de preparation
FR2506767A1 (fr) Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T.

Effective date: 19940331