DK463986A - (n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne - Google Patents

(n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne Download PDF

Info

Publication number
DK463986A
DK463986A DK463986A DK463986A DK463986A DK 463986 A DK463986 A DK 463986A DK 463986 A DK463986 A DK 463986A DK 463986 A DK463986 A DK 463986A DK 463986 A DK463986 A DK 463986A
Authority
DK
Denmark
Prior art keywords
hydroxy
substituted
oxo
benzenacetamides
benzamides
Prior art date
Application number
DK463986A
Other languages
English (en)
Other versions
DK463986D0 (da
Inventor
David T Connor
Daniel L Flynn
Wiaczeslaw A Cetenko
Jagadish C Sircar
Charles F Schwender
Elizabeth A Johnson
Roderick J Sorenson
Paul C Unangst
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK463986D0 publication Critical patent/DK463986D0/da
Publication of DK463986A publication Critical patent/DK463986A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK463986A 1985-10-01 1986-09-29 (n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne DK463986A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/782,763 US4939133A (en) 1985-10-01 1985-10-01 N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade

Publications (2)

Publication Number Publication Date
DK463986D0 DK463986D0 (da) 1986-09-29
DK463986A true DK463986A (da) 1987-04-02

Family

ID=25127108

Family Applications (1)

Application Number Title Priority Date Filing Date
DK463986A DK463986A (da) 1985-10-01 1986-09-29 (n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne

Country Status (10)

Country Link
US (1) US4939133A (da)
EP (1) EP0221346B1 (da)
JP (1) JPS6281359A (da)
AT (1) ATE60575T1 (da)
AU (1) AU606848B2 (da)
DE (1) DE3677320D1 (da)
DK (1) DK463986A (da)
ES (1) ES2005073A6 (da)
GR (1) GR3001880T3 (da)
ZA (1) ZA866940B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3643403A1 (de) * 1986-12-19 1988-06-30 Shell Agrar Gmbh & Co Kg Benzophenone und verfahren zu ihrer herstellung
JP2671059B2 (ja) * 1990-11-30 1997-10-29 富士レビオ株式会社 ナフトエ酸誘導体
US5972980A (en) * 1995-10-05 1999-10-26 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US6001866A (en) * 1995-10-05 1999-12-14 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US6369091B1 (en) 1998-05-22 2002-04-09 Avanir Pharmaceuticals Benzimidazole analogs as down-regulators of IgE
CZ20004350A3 (cs) * 1998-05-22 2002-02-13 Avanir Pharmaceuticals Benzimidazolové deriváty jako modulátory IgE
US6303645B1 (en) 1998-05-22 2001-10-16 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6919366B2 (en) 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
US6653309B1 (en) 1999-04-26 2003-11-25 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme technical field of the invention
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US20070208087A1 (en) * 2001-11-02 2007-09-06 Sanders Virginia J Compounds, compositions and methods for the treatment of inflammatory diseases
KR101088557B1 (ko) * 2000-12-18 2011-12-05 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 염증성 사이토카인 생산 유리 억제제
ATE369853T1 (de) 2001-03-12 2007-09-15 Avanir Pharmaceuticals Benzimidazolderivate zur ige-modulierung und zellproliferationshemmung
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
CA2487891A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the activation of ap-1 and nfat
EP1510207A4 (en) * 2002-06-05 2008-12-31 Inst Med Molecular Design Inc THERAPEUTIC MEDICAMENT AGAINST DIABETES
WO2003103658A1 (ja) * 2002-06-05 2003-12-18 株式会社医薬分子設計研究所 免疫関連プロテインキナーゼ阻害剤
TW200402291A (en) * 2002-06-06 2004-02-16 Inst Med Molecular Design Inc Antiallergic
CA2488363C (en) * 2002-06-06 2011-01-04 Institute Of Medicinal Molecular Design, Inc. O-substituted hydroxyaryl derivatives
US20060014811A1 (en) * 2002-06-10 2006-01-19 Susumu Muto Medicament for treatment of cancer
TW200410675A (en) * 2002-06-10 2004-07-01 Inst Med Molecular Design Inc An NF-κB activation inhibitor
JP4635130B2 (ja) * 2002-06-11 2011-02-16 株式会社医薬分子設計研究所 神経変性疾患治療剤
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
KR20050074949A (ko) * 2002-11-12 2005-07-19 엔오케이 가부시키가이샤 고무형상 탄성부품
AU2006218404A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N-phenyl benzamide derivatives as sirtuin modulators
US8088928B2 (en) * 2005-08-04 2012-01-03 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
US8093401B2 (en) * 2005-08-04 2012-01-10 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
US7855289B2 (en) 2005-08-04 2010-12-21 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
DK1910384T3 (da) * 2005-08-04 2012-12-17 Sirtris Pharmaceuticals Inc Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser
US7671058B2 (en) 2006-06-21 2010-03-02 Institute Of Medicinal Molecular Design, Inc. N-(3,4-disubstituted phenyl) salicylamide derivatives
TW200918542A (en) * 2007-06-20 2009-05-01 Sirtris Pharmaceuticals Inc Sirtuin modulating compounds
CL2008001822A1 (es) * 2007-06-20 2009-03-13 Sirtris Pharmaceuticals Inc Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras.
JP2011502984A (ja) * 2007-11-01 2011-01-27 サートリス ファーマシューティカルズ， インコーポレイテッド サーチュインモジュレーターとしてのアミド誘導体
US20110009381A1 (en) * 2007-11-08 2011-01-13 Sirtis Pharmaceuticals, Inc. Solubilized thiazolopyridines
EP2376502B1 (en) 2008-12-19 2015-06-17 GlaxoSmithKline LLC Thiazolopyridine sirtuin modulating compounds
JP5745501B2 (ja) * 2010-03-25 2015-07-08 国立大学法人 岡山大学 ベンズアニリド誘導体
JP6811196B2 (ja) * 2018-01-10 2021-01-13 日本碍子株式会社 焼成用セッター

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH477163A (de) * 1967-07-26 1969-10-15 Ciba Geigy Verwendung von Salicylsäure-o-hydroxyphenylamiden zum antimikrobiellen Ausrüsten bzw. zum Schützen von textilem Material gegen schädliche Mikroorganismen
DE2600513A1 (de) * 1976-01-08 1977-07-28 Hoechst Ag Acylamino(alkyl)benzolderivate und verfahren zu ihrer herstellung
SU623356A1 (ru) * 1977-03-02 1981-09-07 Пермский ордена Трудового Красного Знамени государственный университет им. А.М.Горького Фениламид @ -бромбензоилпировиноградной кислоты,про вл ющий противоспалительную активность
JPS55113751A (en) * 1979-02-27 1980-09-02 Grelan Pharmaceut Co Ltd 2-oxo-3-(4-aminophenyl)butaneamide and its preparation
IT1198351B (it) * 1981-09-21 1988-12-21 Montedison Spa Processo per la carbonilazione di alogenuri benzilici secondari
US4562201A (en) * 1982-07-26 1985-12-31 American Hospital Supply Corporation Aminomethyl benzanilides
US4742083A (en) * 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
FR2593499B1 (fr) * 1986-01-30 1988-08-12 Jouveinal Sa Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique

Also Published As

Publication number Publication date
DE3677320D1 (de) 1991-03-07
ZA866940B (en) 1988-04-27
GR3001880T3 (en) 1992-11-23
EP0221346A1 (en) 1987-05-13
EP0221346B1 (en) 1991-01-30
ATE60575T1 (de) 1991-02-15
AU6279186A (en) 1987-04-02
US4939133A (en) 1990-07-03
ES2005073A6 (es) 1989-03-01
AU606848B2 (en) 1991-02-21
JPS6281359A (ja) 1987-04-14
DK463986D0 (da) 1986-09-29

Similar Documents

Publication Publication Date Title
DK463986D0 (da) (n-substitueret-2-hydroxy)-benzamider og n-substitueret-2-hydroxy-alfa-oxo-benzenacetamider, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
DK586085A (da) Piperazinderivater og fremgangsmaade til deres fremstilling
NO843836L (no) Terapeutisk aktive sulfamatderivater
FR2371436A1 (fr) Nouveaux derives de morpholine ou de piperidine utiles comme medicaments et comme fongicides
DE3762618D1 (de) Amidderivate.
DE68914292D1 (de) Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
NO885096L (no) Substituerte benzazepiner, deres fremstilling og farmasoeytiske preparater inneholdende disse.
ES2036562T3 (es) Un procedimiento para produccion de un derivado de pirrolidinamida.
FR2800735B1 (fr) Nouvelles aralkyle-1,2-diamines possedant une activite calcimimetique et leur mode de preparation
FR2431505A1 (fr) Nouveaux n-(diaminophosphinyl)arylcarboxamides, utiles notamment comme inhibiteurs de l'urease
ATE109770T1 (de) Derivate der coffeinsäure und pharmazeutische zusammensetzungen, die sie enthalten.
DK161319C (da) Dihydroxyquinoxalinforbindelser, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK183789D0 (da) 2-alkyl-3-benzoylbenzofuraner og laegemidler indeholdende disse
DE3362504D1 (en) 1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use
ES470916A1 (es) Ÿun procedimiento para la preparacion de derivados de acidos4-hidroxi-2-quinolinon-3-carboxilicosŸ
DE3671012D1 (de) 5-alkylsulfonylsalicylanilide und mikrobizide zusammensetzungen fuer die regulierung des wachstums von mikroorganismen.
FR2377382A1 (fr) Nouveaux phenylazacycloalcanes utiles comme medicaments
ATE30152T1 (de) 1-methyl-5-nitro-imidazolin-derivate und diese enthaltende therapeutische zusammensetzungen.
DK601583D0 (da) Carbamyloxybenzhydrolderivater
FR2395995A1 (fr) Nouveaux derives d'a-vinylaminoacides, leur preparation et leur utilisation comme inhibiteurs de la decarboxylase des aminoacides aromatiques
BG46152A3 (en) Herbicide composition
NO881734L (no) Tiadiazolguanidiner og fremgangsmaate for deres fremstilling.
ES8605467A1 (es) Procedimiento para la preparacion de derivados de 1-(amino- fenil)-2-amino-etanona
FR2401133A1 (fr) Nouveaux derives d'aminoacides a-acetyleniques, leur preparation et leur utilisation comme inhibiteurs de la decarboxylase des aminoacides aromatiques
EA200100806A1 (ru) Производные алкинилсодержащих гидроксамовых кислот, способы их получения и применение указанных веществ в качестве ингибиторов матриксной металлопротеиназы (ммр) и фно-альфа-конвертирующего фермента (tace)

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment