BE900178A - Urees et thio-urees anti-atherosclerotiques. - Google Patents
Urees et thio-urees anti-atherosclerotiques.Info
- Publication number
- BE900178A BE900178A BE0/213345A BE213345A BE900178A BE 900178 A BE900178 A BE 900178A BE 0/213345 A BE0/213345 A BE 0/213345A BE 213345 A BE213345 A BE 213345A BE 900178 A BE900178 A BE 900178A
- Authority
- BE
- Belgium
- Prior art keywords
- urea
- atherosclerotic
- thio
- ureas
- hyperlipidemia
- Prior art date
Links
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 3
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title 2
- 230000000879 anti-atherosclerotic effect Effects 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 235000013877 carbamide Nutrition 0.000 abstract 2
- 150000003672 ureas Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51532183A | 1983-07-19 | 1983-07-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE900178A true BE900178A (fr) | 1985-01-18 |
Family
ID=24050874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/213345A BE900178A (fr) | 1983-07-19 | 1984-07-18 | Urees et thio-urees anti-atherosclerotiques. |
Country Status (7)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378728A (en) * | 1992-11-03 | 1995-01-03 | Sandoz Ltd. | Benzoic acid derivatives as antidiabetic agents |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH642342A5 (fr) * | 1979-09-13 | 1984-04-13 | Firmenich & Cie | Procede pour la preparation de muscone. |
US5003106A (en) * | 1983-07-19 | 1991-03-26 | American Cyanamid Company | Antiatherosclerotic ureas and thioureas |
US5248688A (en) * | 1986-09-10 | 1993-09-28 | Dudrick Medical Research Fund I, Ltd. | Method and substrate composition for treating atherosclerosis |
US5032608A (en) * | 1986-09-10 | 1991-07-16 | Dudrick Stanley J | Method and substrate composition for treating atherosclerosis |
US4994465A (en) * | 1989-02-17 | 1991-02-19 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds |
GB9020841D0 (en) * | 1990-09-25 | 1990-11-07 | Wellcome Found | Anti-atherosclerotic aryl compounds |
KR0169501B1 (ko) * | 1990-11-26 | 1999-03-20 | 우에하라 아키라 | 아닐리드 유도체 |
US5420164A (en) * | 1991-04-04 | 1995-05-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Cycloalkylurea compounds |
AU660346B2 (en) * | 1991-12-25 | 1995-06-22 | Taisho Pharmaceutical Co., Ltd. | Anilide derivative |
JPH05320143A (ja) * | 1992-03-18 | 1993-12-03 | Mochida Pharmaceut Co Ltd | 新規ピリミジン誘導体 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5224104B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-10-07 | 1977-06-29 | ||
JPS5461149A (en) * | 1977-10-20 | 1979-05-17 | Kumiai Chem Ind Co Ltd | 3-chloro-4-fluorophenyl urea derivative, its preparation and herbicide containing the same |
US4387105A (en) * | 1982-01-26 | 1983-06-07 | American Cyanamid Company | Methods of treating atherosclerosis with dialkylureas and dialkylthioureas |
IL67417A (en) * | 1982-01-26 | 1989-10-31 | American Cyanamid Co | Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them |
US4387106A (en) * | 1982-01-26 | 1983-06-07 | American Cyanamid Company | Method of treating atherosclerosis with di(aralkyl)ureas and di(aralkyl)thioureas |
-
1984
- 1984-07-05 GB GB08417126A patent/GB2149394B/en not_active Expired
- 1984-07-17 AT AT0231284A patent/AT394191B/de not_active IP Right Cessation
- 1984-07-17 CA CA000459032A patent/CA1239150A/en not_active Expired
- 1984-07-18 BE BE0/213345A patent/BE900178A/fr not_active IP Right Cessation
- 1984-07-18 NL NL8402272A patent/NL8402272A/nl not_active Application Discontinuation
- 1984-07-18 JP JP59147751A patent/JPS6041655A/ja active Granted
- 1984-07-19 FR FR8411471A patent/FR2549473B1/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378728A (en) * | 1992-11-03 | 1995-01-03 | Sandoz Ltd. | Benzoic acid derivatives as antidiabetic agents |
Also Published As
Publication number | Publication date |
---|---|
ATA231284A (de) | 1991-08-15 |
GB8417126D0 (en) | 1984-08-08 |
JPH0585543B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-12-07 |
FR2549473A1 (fr) | 1985-01-25 |
AT394191B (de) | 1992-02-10 |
JPS6041655A (ja) | 1985-03-05 |
GB2149394B (en) | 1986-09-24 |
GB2149394A (en) | 1985-06-12 |
NL8402272A (nl) | 1985-02-18 |
FR2549473B1 (fr) | 1988-07-22 |
CA1239150A (en) | 1988-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: AMERICAN CYANAMID CY Effective date: 19990731 |