GB8417126D0 - Antiatherosclerotic ureas and thioureas - Google Patents

Antiatherosclerotic ureas and thioureas

Info

Publication number
GB8417126D0
GB8417126D0 GB848417126A GB8417126A GB8417126D0 GB 8417126 D0 GB8417126 D0 GB 8417126D0 GB 848417126 A GB848417126 A GB 848417126A GB 8417126 A GB8417126 A GB 8417126A GB 8417126 D0 GB8417126 D0 GB 8417126D0
Authority
GB
United Kingdom
Prior art keywords
antiatherosclerotic
thioureas
ureas
antiatherosclerotic ureas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB848417126A
Other versions
GB2149394B (en
GB2149394A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB8417126D0 publication Critical patent/GB8417126D0/en
Publication of GB2149394A publication Critical patent/GB2149394A/en
Application granted granted Critical
Publication of GB2149394B publication Critical patent/GB2149394B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB08417126A 1983-07-19 1984-07-05 Ureas Expired GB2149394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51532183A 1983-07-19 1983-07-19

Publications (3)

Publication Number Publication Date
GB8417126D0 true GB8417126D0 (en) 1984-08-08
GB2149394A GB2149394A (en) 1985-06-12
GB2149394B GB2149394B (en) 1986-09-24

Family

ID=24050874

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08417126A Expired GB2149394B (en) 1983-07-19 1984-07-05 Ureas

Country Status (7)

Country Link
JP (1) JPS6041655A (en)
AT (1) AT394191B (en)
BE (1) BE900178A (en)
CA (1) CA1239150A (en)
FR (1) FR2549473B1 (en)
GB (1) GB2149394B (en)
NL (1) NL8402272A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH642342A5 (en) * 1979-09-13 1984-04-13 Firmenich & Cie PROCESS FOR THE PREPARATION OF MUSCON.
US5003106A (en) * 1983-07-19 1991-03-26 American Cyanamid Company Antiatherosclerotic ureas and thioureas
US5248688A (en) * 1986-09-10 1993-09-28 Dudrick Medical Research Fund I, Ltd. Method and substrate composition for treating atherosclerosis
US5032608A (en) * 1986-09-10 1991-07-16 Dudrick Stanley J Method and substrate composition for treating atherosclerosis
US4994465A (en) * 1989-02-17 1991-02-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds
GB9020841D0 (en) * 1990-09-25 1990-11-07 Wellcome Found Anti-atherosclerotic aryl compounds
CA2096970C (en) * 1990-11-26 1998-07-14 Masakazu Sato Anilide derivative
US5420164A (en) * 1991-04-04 1995-05-30 Yoshitomi Pharmaceutical Industries, Ltd. Cycloalkylurea compounds
US5416212A (en) * 1991-12-25 1995-05-16 Taisho Pharmaceutical Co., Ltd. Anilide derivatives
JPH05320143A (en) * 1992-03-18 1993-12-03 Mochida Pharmaceut Co Ltd New pyrimidine derivative
US5378728A (en) * 1992-11-03 1995-01-03 Sandoz Ltd. Benzoic acid derivatives as antidiabetic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5224104B2 (en) * 1974-10-07 1977-06-29
JPS5461149A (en) * 1977-10-20 1979-05-17 Kumiai Chem Ind Co Ltd 3-chloro-4-fluorophenyl urea derivative, its preparation and herbicide containing the same
US4387105A (en) * 1982-01-26 1983-06-07 American Cyanamid Company Methods of treating atherosclerosis with dialkylureas and dialkylthioureas
US4387106A (en) * 1982-01-26 1983-06-07 American Cyanamid Company Method of treating atherosclerosis with di(aralkyl)ureas and di(aralkyl)thioureas
IL67417A (en) * 1982-01-26 1989-10-31 American Cyanamid Co Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2549473A1 (en) 1985-01-25
GB2149394B (en) 1986-09-24
FR2549473B1 (en) 1988-07-22
ATA231284A (en) 1991-08-15
JPS6041655A (en) 1985-03-05
CA1239150A (en) 1988-07-12
NL8402272A (en) 1985-02-18
AT394191B (en) 1992-02-10
BE900178A (en) 1985-01-18
JPH0585543B2 (en) 1993-12-07
GB2149394A (en) 1985-06-12

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19990705